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Cellular senescence induced by cholesterol accumulation is mediated by lysosomal ABCA1 in APOE4 and AD
Published 2025-02-01Subjects: Get full text
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Propofol Suppresses Proinflammatory Cytokine Production by Increasing ABCA1 Expression via Mediation by the Long Noncoding RNA LOC286367
Published 2018-01-01“…Here, we provide evidence that in addition to inducing ABCA1 expression, propofol represses proinflammatory cytokine production by increasing ABCA1 expression in a LOC286367-dependent manner. …”
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Role of high-density lipoprotein cholesterol in health and diseases
Published 2021-01-01Subjects: “…abca1…”
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Genetic Polymorphisms in RNF138, ABCA1 and ESRRG-GPATCH2 Genes and their Role in Insulin Resistance Risk among Normal BMI Individuals in Indian Population: A Case-control Study
Published 2025-01-01“…Aim: To fill the knowledge gap by investigating the association of specific gene variants (RNF138, ABCA1, and Oestrogen-Related Receptor γ (ESRRG)-GPATCH2) with IR risk in this demographic. …”
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Single‐cell RNA‐sequencing and spatial transcriptomic analysis reveal a distinct population of APOE− cells yielding pathological lymph node metastasis in papillary thyroid cancer...
Published 2025-01-01Subjects: “…APOE‐ABCA1‐LXR axis…”
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Association of ATP-Binding Cassette Transporter A1 Gene Polymorphisms in Type 2 Diabetes Mellitus among Malaysians
Published 2015-01-01“…R219K polymorphism of ABCA1 gene can be considered as a genetic risk factor for T2DM subjects among Malaysians.…”
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Reverse Cholesterol Transport Pathway and Cholesterol Efflux in Diabetic Retinopathy
Published 2021-01-01“…Particular attention has been paid to the key regulators of the RCT pathway: LXR, ABCA1, and ABCG1 genes and their potential therapeutic targets in the management of DR.…”
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Laboratory Restructuring and Service Support for Infection Control Programs
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Construction of the bromodomain-containing protein-associated prognostic model in triple-negative breast cancer
Published 2025-01-01“…The expression of KRT6A, ABCA1, EDNRB, and CTSD went decreased progressively in pseudotime. …”
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The Efficient Method for Calculating the Physical Optics Scattered Fields from the Concave Surfaces
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The genetic architecture of resistance to flubendiamide insecticide in Helicoverpa armigera (Hübner).
Published 2025-01-01“…Other loci identified by GWAS in field populations contained known insecticide detoxification genes from the ATP-binding cassette family, ABCA1, ABCA3, ABCF2 and MDR1. Our findings revealed an oligogenic genetic architecture, contrasting previous reports of monogenic resistance associated with the ryanodine receptor. …”
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β Common Receptor Mediates Erythropoietin-Conferred Protection on OxLDL-Induced Lipid Accumulation and Inflammation in Macrophages
Published 2015-01-01“…Furthermore, EPO-promoted cholesterol efflux and upregulation of ATP-binding cassette (ABC) transporters ABCA1 and ABCG1 were prevented by pretreatment with βCR neutralizing antibody or βCR siRNA. …”
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Inhibition of miR-652-3p Regulates Lipid Metabolism and Inflammatory Cytokine Secretion of Macrophages to Alleviate Atherosclerosis by Improving TP53 Expression
Published 2022-01-01“…The protein levels of ABCA1, ABCG1, PPARα, CRT1, ADRP, and ALBP were detected by western blot assay. …”
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Revisiting ABC Transporters and Their Clinical Significance in Glioblastoma
Published 2025-01-01“…Using the datasets in The Cancer Genome Atlas and Gene Expression Omnibus, we found upregulated ABC transporters that either negatively impacted survival in univariate analyses (ABCA1, ABCA13, ABCB9, ABCD4) or were independent negative prognosis factors for patients with GBM (ABCA13, ABCB9). …”
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Transcriptome analysis of early pregnancy vitamin D status and spontaneous preterm birth.
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Functions of thyroid hormone signaling in regulating melanophore, iridophore, erythrophore, and pigment pattern formation in spotted scat (Scatophagus argus)
Published 2025-01-01“…Besides, the expression of genes associated with carotenoids and pteridine metabolism (apod, pnpla2, rdh12, stard10, xdh, abca1, retsat, scarb1, rgs2, and gch1) and carotenoids accumulation were stimulated, when thyroid hormone signaling was disrupted by TU. …”
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