iPSC-hepatocyte organoids as a novel platform to predict AAV gene therapy efficacy by Estelle Berreur, Giacomo Lazzaroni, Cyrill Roth, Marco Zihlmann, Martina Stirn, Ramona Matheis, Rebecca Xicluna, Ekaterina Breous-Nystrom, Adrian B. Roth

Subjects: “…AAV vectors…”
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Long-term inhibition of Hepatitis B virus gene expression by a primary microrna expressing ancestral adeno-associated viral vector by Njabulo Ziphezinhle Mnyandu, Shonisani Wendy Limani, Abdullah Ely, Reubina Wadee, Patrick Arbuthnot, Mohube Betty Maepa

Subjects: “…AAV…”
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Development of cell-based assay for detecting replication-competent adeno-associated virus by qPCR by Aishwarya Shevade, John S. Reeves, Hanne Bak, Andrew D. Tustian

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Evaluation of the loading capacity and patterns of packaged DNA in AAV genomes of different sizes using long-read sequencing by Mitsuki Kosaka, Ai Fujita Sajiki, Kosuke Fujita, Kazuhisa Yamada, Kenichi Kawano, Kiichi Hirazawa, Tsuyoshi Matsuno, Masahiko Takada, Nobuhiro Shimozawa, Ken-ichi Inoue, Kenya Yuki, Koji M. Nishiguchi

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A comprehensive study of AAV tropism across C57BL/6 mice, BALB/c mice, and crab-eating macaques by Kailun Fang, Xiali Yang, Yuanhua Liu, Junhui Xia, Ruoxi Wu, Fan Yang, Canbin Feng, Xinyu Liu, Linyu Shi, Guannan Geng, Hui Yang

Subjects: “…AAV tropism…”
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Common AAV gene therapy vectors show nonselective transduction of ex vivo human brain tissue by JP McGinnis, Joshua Ortiz-Guzman, Maria Camila Guevara, Sai Mallannagari, Benjamin D.W. Belfort, Suyang Bao, Snigdha Srivastava, Maria Morkas, Emily Ji, Angela Addison, Evelyne K. Tantry, Sarah Chen, Ying Wang, Zihong Chen, Kalman A. Katlowitz, Jeffrey J. Lange, Melissa M. Blessing, Carrie A. Mohila, M. Cecilia Ljungberg, Guillermo Aldave, Ali Jalali, Akash Patel, Sameer A. Sheth, Howard L. Weiner, Shankar Gopinath, Ganesh Rao, Akdes Serin Harmanci, Daniel J. Curry, Benjamin R. Arenkiel

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Reversing Pathology in an Aggravated Fabry Mouse Model Using Low-Dose Engineered Human Alpha-Galactosidase A AAV Gene Therapy by Wanida Ruangsiriluk, Mugdha Deshpande, Natalia Boukharov, Girija Rajarshi, Shreya Mukherji, Shipeng Yuan, Jennifer Wiseman, Nancy Chen, Eric Park, Hyelim Cho, Rizwana Islam

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Mass photometry as a robust method for characterizing adeno-associated virus critical quality attributes in gene therapy vector by Guangyu Wang, Lei Yu, Xi Qin, Zexin Zhou, Yong Zhou, Chenggang Liang

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Fusion of Visual Attention and Scene Descriptions With Deep Reinforcement Learning for AAV Indoor Autonomous Navigation by Hussein Samma, Ahmed Abubaker, Mubarak Badamasi Aremu, Mohammed Abdel-Nasser, Sami El-Ferik

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AAV‐mediated Gene Therapy for Hereditary Deafness: Progress and Perspectives by Liyan Zhang, Fangzhi Tan, Jieyu Qi, Yicheng Lu, Xiaohan Wang, Xuehan Yang, Xiangyan Chen, Xinru Zhang, Jinyi Fan, Yinyi Zhou, Li Peng, Nianci Li, Lei Xu, Shiming Yang, Renjie Chai

Subjects: “…AAV…”
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AAV-2 VECTOR INTEGRATE INTO THE OVINE MYOBLAST GENOME RANDOMLY AND PROMOTE DIFFERENTIATION AND PROLIFERATION VIA FOLLISTATIN OVER-EXPRESSION OF ERK1/2 AND AKT SIGNALING PATHWAYS by Mahmood Nazari, Fatemeh Salabi, Lixin Du

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αFAP-specific nanobodies mediate a highly precise retargeting of modified AAV2 capsids thereby enabling specific transduction of tumor tissues by Olaniyi Olarewaju, Franziska Held, Pamela Curtis, Cynthia Hess Kenny, Udo Maier, Tadas Panavas, Francois du Plessis

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Intention Recognition of AAV Swarm Based on GAT-EPool-BiGRU Model by Jiajun Yuan, Xiang Jia, Yu An, Liang Geng, Lei Shu

Subjects: “…AAV swarm…”
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AAV induces hepatic necroptosis and carcinoma in diabetic and obese mice dependent on Pebp1 pathway by Yalan Cheng, Zhentong Zhang, Peidong Gao, Hejin Lai, Wuling Zhong, Ning Feng, Yale Yang, Huimin Yu, Yali Zhang, Yumo Han, Jieya Dong, Zhishui He, Rui Huang, Qiwei Zhai

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GDNF overexpression in astrocytes enhances branching and partially preserves hippocampal function in an Alzheimer’s rat model by Ana Abril Vidal Escobedo, Facundo Peralta, Gustavo Ramón Morel, Martino Avallone, Tomas Björklund, Paula Cecilia Reggiani, Joaquín Pardo

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Novel AAV capsids for intravitreal gene therapy of photoreceptor disorders by Marina Pavlou, Christian Schön, Laurence M Occelli, Axel Rossi, Nadja Meumann, Ryan F Boyd, Joshua T Bartoe, Jakob Siedlecki, Maximilian J Gerhardt, Sabrina Babutzka, Jacqueline Bogedein, Johanna E Wagner, Siegfried G Priglinger, Martin Biel, Simon M Petersen‐Jones, Hildegard Büning, Stylianos Michalakis

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Secreted PD-L1 alleviates inflammatory arthritis in mice through local and systemic AAV gene therapy by Wenjun Li, Wenjun Li, Junjiang Sun, Susi Feng, Ariana La Rosa, Panli Zhang, Eveline Y. Wu, Richard Loeser, Chengwen Li, Chengwen Li, Chengwen Li

Subjects: “…AAV…”
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AAV‐mediated delivery of an anti‐BACE1 VHH alleviates pathology in an Alzheimer's disease model by Marika Marino, Lujia Zhou, Melvin Y Rincon, Zsuzsanna Callaerts‐Vegh, Jens Verhaert, Jérôme Wahis, Eline Creemers, Lidia Yshii, Keimpe Wierda, Takashi Saito, Catherine Marneffe, Iryna Voytyuk, Yessica Wouters, Maarten Dewilde, Sandra I Duqué, Cécile Vincke, Yona Levites, Todd E Golde, Takaomi C Saido, Serge Muyldermans, Adrian Liston, Bart De Strooper, Matthew G Holt

Subjects: “…AAV…”
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Nonclinical strategies and considerations to enable the redosing of gene therapies by Jeffrey S. Moffit, Kathila R. Alatsis, Diann L. Blanset, Nicholas Buss, Payal Rana

Subjects: “…AAV…”
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Development of circular AAV cargos for targeted seamless insertion with large serine integrases by Brett J.G. Estes, Nisha Gandhi, Jessica R. Von Stetina, Dev Paudel, Angela X. Nan, Parth Amin, Joshua Rose, Shuai Wu, Kangni Zheng, Yijun Zhang, Jesse C. Cochrane, Jonathan D. Finn, Jenny Xie

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