Reinvestigation into the role of lipopolysaccharide Glycosyltransferases in Helicobacter pylori protein glycosylation by Hong Li, Xiaoqiong Tang, Tiandi Yang, Tingting Liao, Aleksandra W. Debowski, Tiankuo Yang, Yalin Shen, Hans-Olof Nilsson, Stuart M. Haslam, Barbara Mulloy, Anne Dell, Keith A. Stubbs, Wolfgang Fischer, Rainer Haas, Hong Tang, Barry J. Marshall, Mohammed Benghezal

“…Protein glycosylation has been considered as a fundamental phenomenon shared by all domains of life. …”
Get full text

Neural markers of error processing relate to task performance, but not to substance-related risks and problems and externalizing problems in adolescence and emerging adulthood by Olga D. Boer, Thea Wiker, Shervin H. Bukhari, Rikka Kjelkenes, Clara M.F. Timpe, Irene Voldsbekk, Knut Skaug, Rune Boen, Valerie Karl, Torgeir Moberget, Lars T. Westlye, Ingmar H.A. Franken, Hanan El Marroun, Rene J. Huster, Christian K. Tamnes

“…This might indicate that the Pe, which is thought to reflect conscious error processing, reflects task performance on a response inhibition task better than the ERN, which reflects subconscious error processing. …”
Get full text

Profile of Egyptian pediatrics with COVID-19: insights from healthcare providers in Egypt by Salma ZEl Houchi, Hanaa I. Rady, Iman Iskander, Tamer Abdel Hamid, Salma Abdelrehim Seddik, Amira Aly Hegazy, Ahmed Taha Aboushady, Mohamed Eissa, Sherine Khamis Hussein, Dina Hanoura, Miriam Magdy Aziz, Remon Magdy, Heba Ahmed ElAwady, Esraa A. Elmazzahy

“…This study aims to explore the epidemiological patterns, clinical features, laboratory and radiological characteristics, and outcomes of COVID-19 infection in a group of Egyptian children (≤ 18 years). Methods This observational, cross-sectional study is based on a multicenter questionnaire sent to pediatricians managing COVID-19-infected children, through a convenient sampling approach. …”
Get full text

Physicochemical and Sensory Evaluation of Gummy Candies Fortified with Microcapsules of Guinea Pig (<i>Cavia porcellus</i>) Blood Erythrocytes and Tumbo (<i>Passiflora tarminiana</... by Carlos A. Ligarda-Samanez, Eliana Villano-Limache, Williams Pichihua-Oscco, David Choque-Quispe, Reynaldo Sucari-León, Dante Fermín Calderón Huamaní, Germán De la Cruz, Rober Luciano-Alipio, Wilber Cesar Calsina Ponce, Yolanda Aroquipa-Durán, María José Victoria Campos-Huamaní

“…This approach represents a significant advance in the development of innovative functional foods.…”
Get full text

Qualitative application of the diffusion of innovation theory to maternity waiting homes in rural Zambia by Jeanette L. Kaiser, Rachel M. Fiorillo, Taryn Vian, Thandiwe Ngoma, Kayla J. Kuhfeldt, Michelle L. Munro-Kramer, Davidson H. Hamer, Misheck Bwalya, Viviane R. Sakanga, Jody R. Lori, Eden Ahmed Mdluli, Peter C. Rockers, Godfrey Biemba, Nancy A. Scott

“…Women at intervention sites received sensitization about MWHs from a wider range of sources, including traditional leaders. …”
Get full text

Phase Ib study of pembrolizumab in combination with trastuzumab emtansine for metastatic HER2-positive breast cancer by Sara M Tolaney, Tianyu Li, Edward T Richardson, Judith Agudo, Elizabeth A Mittendorf, Beth Overmoyer, Eric P Winer, Adrienne G Waks, Tanya E Keenan, Nabihah Tayob, Gerburg M Wulf, Victoria Attaya, Leilani Anderson, Ian E Krop, Eliezer M Van Allen

“…Eligible patients had HER2-positive, metastatic breast cancer previously treated with taxane, trastuzumab, and pertuzumab, and were T-DM1-naïve. A dose de-escalation design was used, with a dose-finding cohort followed by an expansion cohort at the recommended phase 2 dose (RP2D), with mandatory baseline biopsies. …”
Get full text

Results from the Population-Based Gutenberg Health Study Revealing Four Altered Autoantibodies in Retinal Vein Occlusion Patients by Katharina Bell, Vanessa M. Beutgen, Stefan Nickels, Katrin Lorenz, Yvonne Scheller, Hisham Elbaz, Tunde Peto, Katharina A. Ponto, Andreas Schulz, Philipp S. Wild, Thomas Münzel, Karl J. Lackner, Irene Schmidtmann, Manfred Beutel, Norbert Pfeiffer, Franz H. Grus, Alexander K. Schuster

“…Retinal vein occlusion (RVO) is the second most common retinal vascular disease and a major cause of visual impairment. In this study, we aimed to observe whether RVO cases have different antibody profiles as a new potential risk factor and whether a conversion of retinal vein occlusion (RVO) to neovascular glaucoma (NVG), one of the major complications, is occurring within a 5-year timeframe. …”
Get full text

Cellular senescence induced by cholesterol accumulation is mediated by lysosomal ABCA1 in APOE4 and AD by Shaowei Wang, Boyang Li, Jie Li, Zhiheng Cai, Cristelle Hugo, Yi Sun, Lu Qian, Julia TCW, Helena C. Chui, Dante Dikeman, Isaac Asante, Stan G. Louie, David A. Bennett, Zoe Arvanitakis, Alan T. Remaley, Bilal E. Kerman, Hussein N. Yassine

“…Abstract Background Cellular senescence, a hallmark of aging, has been implicated in Alzheimer’s disease (AD) pathogenesis. …”
Get full text

Macadamia Oil Supplementation Attenuates Inflammation and Adipocyte Hypertrophy in Obese Mice by Edson A. Lima, Loreana S. Silveira, Laureane N. Masi, Amanda R. Crisma, Mariana R. Davanso, Gabriel I. G. Souza, Aline B. Santamarina, Renata G. Moreira, Amanda Roque Martins, Luis Gustavo O. de Sousa, Sandro M. Hirabara, Jose C. Rosa Neto

Get full text

Registro SBR-AF: Preditores de Recorrência de Taquiarritmia Atrial após Primeira Ablação por Cateter na Fibrilação Atrial by Caique M. P. Ternes, Luis E. Rohde, Alexander Dal Forno, Andrei Lewandowski, Helcio Garcia Nascimento, Gabriel Odozynski, Claudio Ferreira, Enrico G. Ferro, Carisi A. Polanczyk, André Zimerman, Lucas S. Faganello, Eric Pasqualotto, Grazyelle Damasceno, Leandro I. Zimerman, Andre d’Avila

“…Métodos O desfecho primário foi a recorrência de qualquer taquiarritmia atrial (TAA). …”
Get full text

FOTODEGRADAÇÃO NO CLIMA SEMIÁRIDO EM FILMES DE POLI(BUTILENO ADIPATO-CO-TEREFTALATO) PUROS E ADITIVADOS COM ÓLEO ESSENCIAL DE CRAVO DA ÍNDIA (Syzygium aromaticum (L.) Merr.) by Karlos D. E. da Silva, Gabriel B. de L. Vitorino, Chaianne K. da S. Nascimento, Carlos A. de Souza, Amanda C. de O. D. Barros, Ivo D. de L. Silva, Glória M. Vinhas, José F. Q. Pereira, Andréa M. S. S. Brito

“…The mass loss exhibits an increasing trend, reaching a maximum average value of 13%. A decreasing trend was observed for the carbonyl index and a slight increase in the hydroxyl index. …”
Get full text

Dynamic 19F-MRI of pulmonary ventilation in lung transplant recipients with and without chronic lung allograft dysfunction by Mary A. Neal, PhD, Saskia Bos, MD, PhD, Charlotte W. Holland, MRCP, Kieren G. Hollingsworth, Gerard Meachery, FRCP, Arun Nair, MD, FRCP, James L. Lordan, FRCP, Andrew J. Fisher, FRCP, PhD, Peter E. Thelwall, PhD

“…Dynamic 19F-MRI of inhaled perfluoropropane may detect subtle changes in regional lung ventilation and provides a quantitative measure of regional lung function. …”
Get full text

Talking with pregnant women exposed to cannabis use after cannabis legalization: Experiences of professionals working in Québec's social and healthcare system by Karen A. Dominguez-Cancino, Rose Chabot, Yolaine Frossard de Saugy, Kristelle Alunni-Menichini, Lysiane Robidoux-Léonard, Genève Guilbert-Gauthier, Karine Bertrand, Christophe Huỳnh, Pablo Martínez, Helen-Maria Vasiliadis, Nadia L'Espérance, Victoria Massamba, Julie Loslier, José Ignacio Nazif-Munoz

“…Results: We identified three themes: a) how professionals talk about cannabis, b) what they talk about, and c) what practices they follow. …”
Get full text

Diagnostic disparities in inborn errors of immunity: From clinical suspicion to diagnosis by Karen M. Gilbert, PhD, Robert F. LeCates, MA, Alison A. Galbraith, MD, MPH, Paul J. Maglione, MD, PhD, Stephanie Argetsinger, MPH, Nicholas L. Rider, DO, Jocelyn R. Farmer, MD, PhD, Mei-Sing Ong, PhD

“…However, there remains a lack of national studies evaluating diagnostic disparities in IEI. …”
Get full text

Artificial intelligence conversational agents in mental health: Patients see potential, but prefer humans in the loop by Hyein S. Lee, Hyein S. Lee, Colton Wright, Julia Ferranto, Jessica Buttimer, Clare E. Palmer, Andrew Welchman, Kathleen M. Mazor, Kimberly A. Fisher, David Smelson, Laurel O’Connor, Laurel O’Connor, Nisha Fahey, Nisha Fahey, Apurv Soni, Apurv Soni, Apurv Soni

“…Data were collected from December 2022 to February 2023, and three researchers conducted rapid qualitative analysis to identify and synthesize themes.ResultsThe sample included 29 adults (ages 19-66), predominantly under age 35, non-Hispanic, White, and female. Participants reported a range of positive and negative experiences with AI conversational agents. …”
Get full text

Extracellular matrix turnover in severe COVID-19 is reduced by corticosteroids by Janesh Pillay, Antine W. Flikweert, Matijs van Meurs, Marco J. Grootenboers, Simone van der Sar-van der Brugge, Peter H. J. van der Voort, Morten A. Karsdal, Jannie M. B. Sand, Diana J. Leeming, Janette K. Burgess, Jill Moser

“…This study investigated the association between circulating extracellular matrix (ECM) remodeling neo-epitopes and COVID-19 severity, their relationship with mortality, and the effect of DEX on these markers. Methods We conducted a multi-center prospective cohort study involving 226 COVID-19 patients: 157 with severe disease admitted to the ward and 69 with critical disease admitted to the ICU. …”
Get full text

Classification, Diagnosis and Treatment of Sinusitis: Evidence-Based Clinical Practice Guidelines by Arnold Noyek, David Brodovsky, Stephen Coyle, Martin Desrosiers, Saul Frenkiel, Michael Hawke, James D Kellner, David A Kirkpatrick, Sigmund Krajden, Donald E Low, Lionel Mandell, Bernard Marlow, Gerald F Martin, Richard Rival, Lalitha Shankar, David Vaughan, Ian J Witterick

Get full text

Global burden of metabolic dysfunction-associated steatotic liver disease, 2010 to 2021 by Gong Feng, Giovanni Targher, Christopher D. Byrne, Yusuf Yilmaz, Vincent Wai-Sun Wong, Cosmas Rinaldi Adithya Lesmana, Leon A. Adams, Jerome Boursier, George Papatheodoridis, Mohamed El-Kassas, Nahum Méndez-Sánchez, Silvia Sookoian, Laurent Castera, Wah-Kheong Chan, Feng Ye, Sombat Treeprasertsuk, Helena Cortez-Pinto, Hon Ho Yu, Won Kim, Manuel Romero-Gómez, Atsushi Nakajima, Khin Maung Win, Seung Up Kim, Adriaan G. Holleboom, Giada Sebastiani, Ponsiano Ocama, John D. Ryan, Monica Lupșor-Platon, Hasmik Ghazinyan, Mamun Al-Mahtab, Saeed Hamid, Nilanka Perera, Khalid A. Alswat, Qiuwei Pan, Michelle T. Long, Vasily Isakov, Man Mi, Marco Arrese, Arun J. Sanyal, Shiv Kumar Sarin, Nathalie Carvalho Leite, Luca Valenti, Philip N. Newsome, Hannes Hagström, Salvatore Petta, Hannele Yki-Järvinen, Jörn M. Schattenberg, Marlen I. Castellanos Fernández, Isabelle A. Leclercq, Gulnara Aghayeva, Abdel-Naser Elzouki, Ali Tumi, Ala I. Sharara, Asma Labidi, Faisal M. Sanai, Khaled Matar, Maen Al-Mattooq, Maisam Waid Akroush, Mustapha Benazzouz, Nabil Debzi, Maryam Alkhatry, Salma Barakat, Said A. Al-Busafi, John Rwegasha, Wah Yang, Agyei Adwoa, Christopher Kenneth Opio, Mohammadjavad Sotoudeheian, Yu Jun Wong, Jacob George, Ming-Hua Zheng

“…MASLD incidence varied with SDI, peaking at moderate SDI levels. Conclusions: MASLD is a global health concern, with the highest prevalence reported in Kuwait, Egypt, and Qatar. …”
Get full text

Dynamic Challenges of Active Tuberculosis: Prevalence and Risk Factors of Co-Infection in Clinical and Microbiological Characteristics at King Abdulaziz University Hospital, Jeddah... by Mokhtar JA, Attallah DM, Jiman-Fatani AA, Al-Rabia MW, Alqarni MA, Saleh BH, Amboon MM, Altorki TA, Alkuwaity KK, Abujamel T, Kaki R, Albarakati TN, Daghistani H, Ismail MA, Alharbi O, Abu ITM, Alfadil A, Ibrahem K, Mufrrih M, Sait AM

“…This group also showed a higher mortality rate due to comorbidities such as renal failure, human immunodeficiency virus (HIV), and autoimmune disease. …”
Get full text

NIRS-BIDS: Brain Imaging Data Structure Extended to Near-Infrared Spectroscopy by Robert Luke, Robert Oostenveld, Helena Cockx, Guiomar Niso, Maureen J Shader, Felipe Orihuela-Espina, Hamish Innes-Brown, Stephen Tucker, David Boas, Meryem A. Yücel, Remi Gau, Taylor Salo, Stefan Appelhoff, Christopher J. Markiewicz, David McAlpine, The BIDS Maintainers, Luca Pollonini

“…Abstract Functional near-infrared spectroscopy (fNIRS) is an increasingly popular neuroimaging technique that measures cortical hemodynamic activity in a non-invasive and portable fashion. Although the fNIRS community has been successful in disseminating open-source processing tools and a standard file format (SNIRF), reproducible research and sharing of fNIRS data amongst researchers has been hindered by a lack of standards and clarity over how study data should be organized and stored. …”
Get full text