Infection‐Related Hospitalization and Incident Heart Failure: The Atherosclerosis Risk in Communities Study by Rebecca L. Molinsky, Amil Shah, Melana Yuzefpolskaya, Bing Yu, Jeffrey R. Misialek, Bruno Bohn, David Vock, Richard MacLehose, Barry A. Borlaug, Paolo C. Colombo, Chiadi E. Ndumele, Junichi Ishigami, Kunihiro Matsushita, Pamela L. Lutsey, Ryan T. Demmer

“…IRH was identified using select International Classification of Diseases (ICD) codes in hospital discharge records and was treated as a time‐varying exposure. HF incidence was defined as the first occurrence of either a hospitalization that included an ICD, Ninth Revision (ICD‐9) discharge code of 428 (428.0–428.9) among the primary or secondary diagnoses or a death certificate with an ICD‐9 code of 428 or an ICD, Tenth Revision (ICD‐10) code of I50 among any of the listed diagnoses or underlying causes of death. …”
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Non-thermal plasma as promising anti-cancer therapy against bladder cancer by inducing DNA damage and cell cycle arrest by Jojanneke Stoof, Zakaria Kalmoua, Ana Sobota, Ruud H. Brakenhoff, Marijke Stigter, Thang V. Pham, Sander R. Piersma, Alex Henneman, Tonny Lagerweij, Richard de Goeij-de Haas, R. Jeroen A. van Moorselaar, Connie R. Jimenez, Irene V. Bijnsdorp

“…We investigated non-thermal plasma’s potential as a novel anti-cancer therapy, focusing on plasma-activated solution (PAS), created by exposing saline to non-thermal plasma. …”
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Endothelial cell Piezo1 promotes vascular smooth muscle cell differentiation on large arteries by Javier Abello, Ying Yin, Yonghui Zhao, Josh Maurer, Jihui Lee, Cherokee Bodell, Jahmiera Richee, Abigail J. Clevenger, Zarek Burton, Megan E. Goeckel, Michelle Lin, Stephanie Grainger, Carmen M. Halabi, Shreya A. Raghavan, Rajan Sah, Amber N. Stratman

“…Vascular stabilization is a mechanosensitive process, in part driven by blood flow. …”
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The impact of HPV/HIV co-infection on immunosuppression, HPV genotype, and cervical cancer biomarkers by Terkimbi Dominic Swase, Ilemobayo Victor Fasogbon, Ifie Josiah Eseoghene, Ekom Monday Etukudo, Solomon Adomi Mbina, Chebet Joan, Reuben Samson Dangana, Chinyere Anyanwu, Comfort Danchal Vandu, A. B Agbaje, Tijjani Salihu Shinkafi, Ibrahim Babangida Abubarkar, Patrick Maduabuchi Aja

“…Abstract Background Human papillomavirus (HPV) and human immunodeficiency virus (HIV) co-infection present a significant impact on women's health globally, especially in immunocompromised individuals. …”
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Unique North American isolates of severe metastatic hypervirulent Klebsiella pneumoniae strain infections with hepatic abscesses seen in young patients within Texas. by Junaid M Alam, Eric N Riha, Haris Ahmed, Hong M Thai, Kevin Garnepudi, Ramesh B Kesavan, Gnananandh Jayaraman, Anna Sangster, Dylan Curry, Heidi A Butz, Lori Smith, Maureen Vowles, Kelly F Oakeson, Erin L Young, Siva T Sarva

“…<h4>Rationale</h4>Hypervirulent Klebsiella pneumoniae (hvKp) infections have principally been identified in Asia. Within a two-month period, two patients between the ages of 30 to 50 years old presented to a tertiary referral hospital in Texas with septic shock, hepatic abscess, and septic thrombophlebitis. …”
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NLRX1 limits inflammatory neurodegeneration in the anterior visual pathway by Alexander J. Gill, Matthew D. Smith, Danny Galleguillos, Thomas Garton, Jackson W. Mace, Sachin P. Gadani, Swati Kumar, Aayush Pokharel, Krista Solem, Saahith Potluri, Omar Hussein, Giuliana Sardi Rogines, Arihant Singh, Annatje Clark, Peter A. Calabresi, Marjan Gharagozloo

“…This study highlights that NLRX1 could serve as a promising target for neuroprotection in progressive MS and other neurodegenerative diseases. …”
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Employing the concept of stacking ensemble learning to generate deep dream images using multiple CNN variants by Lafta Alkhazraji, Ayad R. Abbas, Abeer S. Jamil, Zahraa Saddi Kadhim, Wissam Alkhazraji, Sabah Abdulazeez Jebur, Bassam Noori Shaker, Mohammed Abdallazez Mohammed, Mohanad A. Mohammed, Basim Mohammed Al-Araji, Abdulkareem Z. Mohmmed, Wasiq Khan, Bilal Khan, Abir Jaafar Hussain

“…Final Deep Dream image showed a loss of 47.5821, while still retaining some features from the base image.…”
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Metagenomic insights into the development of microbial communities of straw and leaf composts by Anastasiia K. Kimeklis, Anastasiia K. Kimeklis, Grigory V. Gladkov, Olga V. Orlova, Tatiana O. Lisina, Alexey M. Afonin, Alexey M. Afonin, Tatiana S. Aksenova, Arina A. Kichko, Alla L. Lapidus, Evgeny V. Abakumov, Evgeny V. Abakumov, Evgeny E. Andronov

“…IntroductionSoil microbiome is a major source of physiologically active microorganisms, which can be potentially mobilized by adding various nutrients. …”
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The matricellular protein Fibulin-5 regulates β-cell proliferation in an autocrine/paracrine manner by Tomoko Okuyama, Takahiro Tsuno, Ryota Inoue, Setsuko Fukushima, Mayu Kyohara, Anzu Matsumura, Daisuke Miyashita, Kuniyuki Nishiyama, Yusuke Takano, Yu Togashi, Makiko Meguro-Horike, Shin-ichi Horike, Tatsuya Kin, A.M. James Shapiro, Hiromi Yanagisawa, Yasuo Terauchi, Jun Shirakawa

“…Summary: The matricellular protein Fibulin-5 (Fbln5) is a secreted protein that is essential for elastic fiber formation, and pancreatic islets are usually surrounded by the extracellular matrix (ECM), which includes elastic fibers. …”
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Aux sources de la spécialisation hémisphérique cérébrale du langage : l'intérêt de l'IRM anatomique chez le babouin by Adrien Meguerditchian, Damien Marie, Muriel Roth, Romain Lacoste, Bruno Nazarian, Ivan Balansard, Jean-Luc Anton, Olivier Coulon, Alice Bertello, Jean-Noël Benoit, Scott A. Love, Thomas Brochier, Martine Meunier, Sandrine Melot‑Dusseau, Jean‑Christophe Marin, William D Hopkins

“…Dans cette présentation, nous introduirons nos travaux en neuroimagerie non invasive IRM (Imagerie par résonance magnétique) menés sur des babouins Papio anubis  anesthésiés puis remis dans leur groupe social. Ces recherches visent à constituer une base de données la plus large possible d'images cérébrales anatomiques auprès de sujets hébergés et observés à la station de primatologie de Rousset. …”
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New Record of <i>Encarsia protransvena</i> and Confirmed Occurrence of <i>Encarsia hispida</i> (Hymenoptera: Aphelinidae) as Parasitoids of <i>Singhiella simplex</i> (Hemiptera: Al... by Giuliano Cerasa, Luigi Tomasello, Gianluca Melone, Elia Russo, Gaetano Siscaro, Carmelo Cavallaro, Annamaria Ienco, Francesca Laudani, Vincenzo Palmeri, Orlando Campolo, Francesca Garganese, Francesco Porcelli, Paolo A. Pedata, Vittorio Farina, Giovanni Gugliuzza, Roberto Rizzo, Stefania Laudonia, Gabriella Lo Verde

“…<i>Encarsia protransvena</i> (Hymenoptera: Aphelinidae) is recorded here for the first time in Italy as a parasitoid of the whitefly <i>Singhiella simplex</i> (Hemiptera: Aleyrodidae), one of the most invasive alien pests of exotic <i>Ficus</i> species. …”
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The ArcB kinase sensor participates in the phagocyte-mediated stress response in Salmonella Typhimurium by Coral Pardo-Esté, Coral Pardo-Esté, Francisca Urbina, Nicolas Aviles, Nicolas Pacheco, Alan Briones, Carolina Cabezas, Vicente Rojas, Valentina Pavez, Yoelvis Sulbaran-Bracho, Yoelvis Sulbaran-Bracho, Alejandro A. Hidalgo, Juan Castro-Severyn, Juan Castro-Severyn, Claudia P. Saavedra

“…The ArcAB two-component system includes a histidine kinase sensor (ArcB) and a regulator (ArcA) that respond to changes in cell oxygen availability. …”
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Ultra high density imaging arrays in diffuse optical tomography for human brain mapping improve image quality and decoding performance by Zachary E. Markow, Jason W. Trobaugh, Edward J. Richter, Kalyan Tripathy, Sean M. Rafferty, Alexandra M. Svoboda, Mariel L. Schroeder, Tracy M. Burns-Yocum, Karla M. Bergonzi, Mark A. Chevillet, Emily M. Mugler, Adam T. Eggebrecht, Joseph P. Culver

“…Herein, simulations indicated reducing inter-optode spacing to 6.5 mm, creating a higher-density grid with more source-detector distances, would further improve image quality and noise-resolution tradeoff, with diminishing returns below 6.5 mm. …”
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Investigating the impact of microbiome-changing interventions on food decision-making: MIFOOD study protocol by Meghedi Vartanian, Konrad Jakob Endres, Yee Teng Lee, Silke Friedrich, Marie-Theres Meemken, Imke Schamarek, Kerstin Rohde-Zimmermann, Robin Schürfeld, Lina Eisenberg, Anja Hilbert, Frauke Beyer, Michael Stumvoll, Julia Sacher, Arno Villringer, Julia F. Christensen, A. Veronica Witte

“…We therefore aim to examine the effects of prebiotic and neurocognitive behavioral interventions on food decision-making and to assay the underlying mechanisms in a Randomized Controlled Trial (RCT). Method This study uses a parallel arm RCT design with a 26-week intervention period. …”
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The Research Agenda for Perinatal Innovation and Digital Health Project: Human-Centered Approach to Multipartner Research Agenda Codevelopment by Haneen Amhaz, Sally Xuanping Chen, Amanee Elchehimi, Kylin Jialin Han, Jade Morales Gil, Lu Yao, Marianne Vidler, Kathryn Berry-Einarson, Kathryn Dewar, May Tuason, Nicole Prestley, Quynh Doan, Tibor van Rooij, Tina Costa, Gina Ogilvie, Beth A Payne

“… BackgroundDigital health innovations provide an opportunity to improve access to care, information, and quality of care during the perinatal period, a critical period of health for mothers and infants. …”
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Treatment time and learning curve analysis of 1.5 T MR-Linac workflows led by radiation oncologists or therapists by J.M. Westerhoff, F.J. Raaijmakers, L.A. Daamen, E.N. de Groot-van Breugel, L.T.C. Meijers, J.R.N. van der Voort van Zyp, J.J.C. Verhoeff, S. Mook, H.M. Verkooijen, M.P.W. Intven

“…Adapt-to-Position, ATP) magnetic resonance guided radiotherapy (MRgRT) on a 1.5 Tesla MR-Linac. Additionally, the transition from a radiation oncologists (RO)-led to a radiation therapist (RTT)-led workflow, and the presence of a learning curve were assessed. …”
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Paving the Way for Integrated Advanced Heart Failure and Adult Congenital Heart Disease Training by William H. Marshall V., MD, Ryan D. Byrne, MD, Andrew Civitello, MD, William J. Dreyer, MD, Peter R. Ermis, MD, Brent C. Lampert, DO, Lauren T. Lastinger, MD, Deipanjan Nandi, MD, Joseph A. Spinner, MD, Curt J. Daniels, MD

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Author Correction: Prospective de novo drug design with deep interactome learning by Kenneth Atz, Leandro Cotos, Clemens Isert, Maria Håkansson, Dorota Focht, Mattis Hilleke, David F. Nippa, Michael Iff, Jann Ledergerber, Carl C. G. Schiebroek, Valentina Romeo, Jan A. Hiss, Daniel Merk, Petra Schneider, Bernd Kuhn, Uwe Grether, Gisbert Schneider

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Use of supervised and unsupervised approaches to make zonal application maps for variable-rate application of crop growth regulators in commercial cotton fields by Maria C. da S. Andrea, Cristiano F. de Oliveira, Fabrícia C. M. Mota, Rafael C. dos Santos, Edilson F. Rodrigues Junior, Lucas M. Bianchi, Rodrigo S. de Oliveira, Caio M. de Gouveia, Victor G. S. Barbosa, Marco A. Bispo E Silva

“…These include the availability of specialized machinery required for this type of applications, as well as the inherent operational costs associated with applying a single CGR product which differs from the typical uniform rate applications that often integrate multiple inputs. …”
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Elevated Urinary Connective Tissue Growth Factor in Diabetic Nephropathy Is Caused by Local Production and Tubular Dysfunction by Karin G. F. Gerritsen, Jan Willem Leeuwis, Maarten P. Koeners, Stephan J. L. Bakker, Willem van Oeveren, Jan Aten, Lise Tarnow, Peter Rossing, Jack F. M. Wetzels, Jaap A. Joles, Robbert Jan Kok, Roel Goldschmeding, Tri Q. Nguyen

“…Connective tissue growth factor (CTGF; CCN2) plays a role in the development of diabetic nephropathy (DN). …”
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