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101541
Multi-modal comparison of molecular programs driving nurse cell death and clearance in Drosophila melanogaster oogenesis.
Published 2025-01-01“…The death and clearance of nurse cells is a consequential milestone in Drosophila melanogaster oogenesis. …”
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101542
History and Habitability of the LP 890-9 Planetary System
Published 2025-01-01“…However, if the planet forms with a hydrogen envelope as small as 0.1 Earth masses, no water will be lost during the star's pre-main-sequence phase from thermal escape processes. …”
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101544
Theoretical Study of Sphingomyelinases from <i>Entamoeba histolytica</i> and <i>Trichomonas vaginalis</i> Sheds Light on the Evolution of Enzymes Needed for Survival and Colonizati...
Published 2025-01-01“…The path to survival for pathogenic organisms is not straightforward. Pathogens require a set of enzymes for tissue damage generation and to obtain nourishment, as well as a toolbox full of alternatives to bypass host defense mechanisms. …”
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101545
Life-Threatening Rupture of an Idiopathic Left Hepatic Artery Pseudoaneurysm Successfully Treated with Endovascular Coil Embolization
Published 2020-01-01“…Hepatic artery pseudoaneurysm is a rare condition; they are multifactorial, most of them locating in the extrahepatic vasculature and the mortality associated to its rupture may reach up to 70%. …”
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101546
Experimental study and gyrokinetic simulations of isotope effects on core heat transport in JET tokamak deuterium and tritium plasmas
Published 2025-01-01“…This paper presents a study on the dependence of the ion temperature stiffness on the plasma main ion isotope mass in JET ITER-like wall and C wall discharges. …”
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101547
Epigallocatechin gallate (EGCG) modulates senescent endothelial cell-monocyte communication in age-related vascular inflammation
Published 2025-01-01“…Human umbilical vein endothelial cells (HUVECs) were treated with Etoposide (10 µM, 24 h) to induce senescence, followed by EGCG (100 µM, 24 h) treatment to evaluate its potential as a senotherapeutic agent. The interaction between ECs and monocytes was analyzed using a co-culture system and direct treatment of monocytes with EC-derived EVs. …”
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101548
Malian field isolates provide insight into Plasmodium malariae intra-erythrocytic development and invasion.
Published 2025-01-01“…Nevertheless, our comprehension of this parasite's biology remains limited, primarily due to its frequent co-infections with other species and the lack of a continuous in vitro culture system. To effectively combat and eliminate this overlooked parasite, it is imperative to acquire a better understanding of this species. …”
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GrB-Fc-KS49, an anti-EMP2 granzyme B fusion protein therapeutic alters immune cell infiltration and suppresses breast cancer growth
Published 2024-12-01“…Background Granzyme B (GrB) is a key effector molecule, delivered by cytotoxic T lymphocytes and natural killer cells during immune surveillance to induce cell death. …”
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101550
Bioassays for the evaluation of the attractiveness of attractive targeted sugar bait (ATSB) against Anopheles mosquitoes in controlled semi-field systems
Published 2025-02-01“…The findings indicate that future bioassays to evaluate ATSBs should use mosquitoes of both sexes, aged 3–5 days, include multiple species in the same cage or chamber, and utilize both non-choice and choice tests with a standard comparator.…”
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101551
Fast 3D printing of fine, continuous, and soft fibers via embedded solvent exchange
Published 2025-01-01“…Here, we demonstrate multi-nozzle printing of 3D hair arrays having freeform trajectories at a very high rate, with fiber diameters as fine as 1.5 µm, continuous lengths reaching tens of centimeters, and a wide range of materials with elastic moduli from 5 MPa to 3500 MPa. …”
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101552
Thioredoxin 1 in Prostate Tissue Is Associated with Gleason Score, Erythrocyte Antioxidant Enzyme Activity, and Dietary Antioxidants
Published 2015-01-01“…Greater Gleason score of malignant tissue corresponds to a greater difference in Trx 1 levels between malignant and benign tissue (P=0.04). …”
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Rimegepant for the treatment of migraine
Published 2022-10-01“…Migraine is a common form of primary headache, affecting up to 1 in every 6 Americans. …”
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101554
Differential Signature of the Centrosomal MARK4 Isoforms in Glioma
Published 2011-01-01“…Background: MAP/microtubule affinity-regulating kinase 4 (MARK4) is a serine-threonine kinase expressed in two spliced isoforms, MARK4L and MARK4S, of which MARK4L is a candidate for a role in neoplastic transformation. …”
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The transcription factor combination MEF2 and KLF7 promotes axonal sprouting in the injured spinal cord with functional improvement and regeneration-associated gene expression
Published 2025-02-01“…Next, adeno-associated viral vectors were used to express these TF combinations in vivo in L4/L5 dorsal root ganglia to test whether they would promote regeneration in a spinal cord injury model (dorsal column lesion) in female rats. …”
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Multicentre, 26-week, open-label phase 2 trial of the JAK inhibitor filgotinib in Behçet’s disease, idiopathic inflammatory myopathies and IgG4-related disease: DRIMID study protoc...
Published 2025-02-01“…The trial consists of two stages, each involving a consecutively treated cohort of up to 20 patients per disease. …”
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An automated platform for simultaneous, longitudinal analysis of engineered neuromuscular tissues for applications in neurotoxin potency testing
Published 2025-01-01“…Dose-response studies using botulinum neurotoxin showed loss of function in a dose- and time-dependent manner (EC50 − 0.11 ± 0.015 µg). …”
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Genomic insights into multidrug-resistant Acinetobacter baumannii strains isolated from Dhaka, Bangladesh
Published 2025-03-01“…Multidrug-resistant (MDR) A. baumannii is a growing concern to the healthcare system in Bangladesh, necessitating the elucidation of the genetic characteristics of this species. …”
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