Sequential Kinase Inhibition (Idelalisib/Ibrutinib) Induces Clinical Remission in B-Cell Prolymphocytic Leukemia Harboring a 17p Deletion by H. Coelho, M. Badior, T. Melo

“…B-cell prolymphocytic leukemia (B-PLL) is a rare lymphoid neoplasm with an aggressive clinical course. …”
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Perfil dos atendimentos antirrábicos pós-exposição a mamíferos silvestres em região de saúde, Pernambuco, Brasil, 2014-2020 by Laysa Lindaura Lau Rocha Cordeiro, Maria Olívia Soares Rodrigues, Louisiana Regadas de Macedo Quinino, Francisco Duarte Farias Bezerra, Raylene Medeiros Ferreira Costa, Emília Carolle Azevedo de Oliveira

“…Justificativa e Objetivos: desde 2016, o Brasil não registra casos de raiva humana transmitida por cães, com a doença agora associada principalmente a mamíferos silvestres. …”
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Anaerobic digestion bacteria algae (ADBA): A mathematical model of mixotrophic algal growth with indigenous bacterial inhibition in anaerobic digestion effluent by S M Hasan Shahriar Rahat, Oluwatunmise Israel Dada, Liang Yu, Helmut Kirchhoff, Shulin Chen

“…A comprehensive kinetic model called anaerobic digestion bacteria algae (ADBA) was developed to describe and predict the complex algae-bacterial system in anaerobic digestion (AD) wastewater under mixotrophic growth conditions. …”
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The Effect of Diacerein on Type 2 Diabetic Mellitus: A Systematic Review and Meta-Analysis of Randomized Controlled Trials with Trial Sequential Analysis by Shizhe Guo, Xianshan Guo, Hongya Zhang, Xuan’e Zhang, Zhen Li

“…Secondary outcomes were glycosylated hemoglobin A1c (HbA1c), body mass index (BMI), lipid profiles, hematological indexes including hematocrit and platelet count, and systematic inflammatory level expressed as a C-reactive protein (CRP) level. …”
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Accuracy of screening tests for cervical precancer in women living with HIV in low-resource settings: a paired prospective study in Lusaka, Zambia by Nicola Low, Partha Basu, Andreas Limacher, Katayoun Taghavi, Misinzo Moono, Mulindi Mwanahamuntu, Herbert Kapesa, Albert Manasyan, Julia Bohlius, Marie Roumet, Thamsanqa Madliwa, Anne Rutjes

“…We assessed the accuracy of screening tests that can be used in low-resource settings and give results at the same visit.Methods and analysis We conducted a paired, prospective study among consecutive eligible WLHIV, aged 18–65 years, receiving cervical cancer screening at one hospital in Lusaka, Zambia. …”
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Innovative Strategy to Improve Precision and to Save Power of a Real-Time Control Process Using an Online Adaptive Fuzzy Logic Controller by R. Lasri, I. Rojas, H. Pomares, O. Valenzuela

“…The main objective of this paper is to prove the great advantage that brings our novel approach to the intelligent control area. A set of various types of intelligent controllers have been designed to control the temperature of a room in a real-time control process in order to compare the obtained results with each other. …”
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Binaural auditory beats vs music of choice as audio distraction behaviour guidance technique among children: A randomized controlled trial by Bhuvanesh N. Bhusari, Shivayogi M. Hugar, Niraj Gokhale, Shweta Kajjari, Sanika Karmarkar, Varunika Sahai

“…Background: Binaural beat is created by presenting two different pure-tone sine waves with less than a 30Hz difference dichotically. In dental settings, children listening to familiar music during treatments gain control over the anxiety caused by tools like the airotor or syringe, creating a comforting, familiar environment. …”
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Association between non-high-density lipoprotein cholesterol and type 2 diabetes: a systematic review and meta-analysis of cohort studies by Mengqi Han, Yue Shen, Xin Guo, Cheng Hong, Xincan Ji, Haoyang Guo, Yuelong Jin, Hui Yuan

“…Non-high-density lipoprotein cholesterol (non-HDL), a more readily available and reliable lipid parameter, is unclear in its association with type 2 diabetes (T2D). …”
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La Unión Europea frente a las emergencias de salud pública mundial. La crisis de la COVID-19 by María Teresa Ponte Iglesias

“…Finalmente, se brinda un reflexión final sobre como la actual pandemia exige a la UE estar preparada para futuras crisis sanitarias.…”
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Characterizing Sparse Spectral Diversity Within a Homogenous Background: Hydrocarbon Production Infrastructure in Arctic Tundra near Prudhoe Bay, Alaska by Daniel Sousa, Latha Baskaran, Kimberley Miner, Elizabeth Josephine Bushnell

“…We explore a new approach for the parsimonious, generalizable, efficient, and potentially automatable characterization of spectral diversity of sparse targets in spectroscopic imagery. …”
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Development of a Portable Rapid Detection Method for Porcine Epidemic Diarrhea Virus Using Reverse Transcription-Recombinase-Aided Amplification Technology by Yiran Zhao, Weijie Yi, Qicheng Yang, Jiahao Li, Yanke Shan, Fei Liu

“…This method enables results to be obtained within 20 min of amplification at a constant temperature of 42 °C. It demonstrates high sensitivity, with a detection limit as low as 1 copy/μL, and shows strong specificity, with no cross-reactivity observed with seven other common swine pathogens. …”
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Real-world safety of linaclotide in Chinese patients with irritable bowel syndrome with constipation: a multicenter, single-arm, prospective observational study by Yinglian Xiao, Xianmei Meng, Qingfeng Luo, Xiaohua Hou, Jie Jin, Xianfei Zhong, Wei Gong, Xiuling Li, Minhu Chen

“…Background: Linaclotide, a guanylate cyclase-C agonist, is indicated for irritable bowel syndrome with constipation (IBS-C). …”
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Causal associations of ambient particulate matter 10 and Alzheimer’s disease: result from a two-sample multivariable Mendelian randomization study by Zehan Huang, Guodong He, Shuo Sun, Yingqing Feng, Yuqing Huang

“…In the univariate MR, pooled meta-analysis of genetically predicted PM10 was associated with a 99% increased risk of AD (95% CI: 1.25, 3.15, p = 0.004) per 1 standard deviation (SD) increment of PM10 by IVW, and in the multivariable MR with pooled meta-analysis, we found that each SD increase in PM10 was associated with a 127% increase in the risk of AD (95% CI: 1.33, 3.86, p = 0.002) after accounting for education levels. …”
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Rancang Bangun Sistem Monitoring Kelembaban Tanah dan Suhu Udara Berbasis GSM SIM900A DAN ARDUINO UNO by Wulantika Sintia, Dedy Hamdani, Eko Risdianto

“… Penelitian ini bertujuan untuk merancang dan membuat alat monitoring kelembaban tanah dan suhu udara pada tanaman berbasis GSM SIM900A dan Arduino Uno, serta mengukur kelembaban tanah dan suhu udara pada tanaman berbasis GSM SIM900A dan Arduino Uno. …”
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RESULTS OF EXPERIMENTAL INFECTION OF TURKEYS WITH A/DUCK/ALTAI/469/14 H5N1 STRAIN OF AVIAN INFLUENZA VIRUS by V. Yu. Sosipatorova, D. A. Altunin, I. A. Chvala, N. S. Mudrak, D. B. Andreychuk

“…The data on experimental infection of 6-week-old Big-6 cross turkeys with an epidemic A/duck/Altai/469/14 H5N1 clade 2.3.2.1c strain of avian influenza virus are presented. …”
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Updates on Prevalence and Trend Status of Visceral Leishmaniasis at Two Health Facilities in Amhara Regional State, Northwest Ethiopia: A Retrospective Study by Mulat Yimer, Endalkachew Nibret, Gizachew Yismaw

“…Data on Sex, age, occupation, residence, month, year, and rK39 test results were collected using a questionnaire and were analyzed using Statistical Package for Social Sciences (SPSS) version 20. …”
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Impact of COVID-19 restrictions on behavioural and psychological symptoms in home-dwelling people with dementia: a prospective cohort study (PAN.DEM) by Maarja Vislapuu, Mala Naik, Bettina S Husebø, Marie H Gedde, Ipsit V Vahia, Janne Mannseth, Line I Berge

“…Mini-Mental Status Examination score 15–26 or Functional Assessment Staging score 3–7 covered dementia severity.Main outcome measures Neuropsychiatric Inventory (NPI-12) total (range 0–144), psychosis (range 0–24), hyperactive behaviour (range 0–60) and mood subsyndrome (range 0–48) scores; Cornell Scale for Depression in Dementia (CSDD) total score (range 0–38).Results We found an overall increase in BPSD by NPI-12 total score comparing prepandemic to pandemic levels (median 16 IQR (4.5–29) to 20 (7–32.5), p=0.03) over a mean of 86 days (SD 19). NPI-12 total score worsened in 57 (55%) of people with dementia and was associated with postponed or averted contacts with healthcare professionals (logistic regression, OR 3.96, 95% CI 1.05 to 14.95). …”
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Improving cognitive impairment through chronic consumption of natural compounds/extracts: a systematic review and meta-analysis of randomized controlled trials by Long Ngo Hoang, Haesung Lee, Sook Jeong Lee

“…Of these, 37 studies demonstrated improvements or positive trends in cognitive outcomes with natural compound or extract supplementation. A total of 35 studies met the criteria for meta-analysis. …”
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Des objets en bois remarquables issus d’un puits de la place d’Assas à Nîmes (Gard) by Pierre Mille, Éric Bayen, Frédéric Conche, Martial Monteil

“…Fifteen rare and remarkable wooden objects were found in this humid environment, such as various boxes, including two boxes with mirrors and two signet boxes, fragments of writing tablets, a hinge from a piece of furniture, three spindle fragments, the base of a wicker basket, etc. …”
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Beyond averages: dissecting urban-rural disparities in skilled antenatal care utilization in Bangladesh - a conway-maxwell-poisson regression analysis by Md. Muddasir Hossain Akib, Farzana Afroz, Bikash Pal

“…Abstract Background Taking a sufficient number of skilled antenatal care (SANC) visits is incontrovertibly connected to safe motherhood. …”
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