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72081
GPX3 as a Novel and Potential Therapeutic Target in the Shared Molecular Mechanisms of Traumatic Brain Injury and Parkinson’s Disease
Published 2025-02-01“…The glutathione peroxidase 3 (GPX3) gene emerged as a pivotal hub gene, with its expression significantly altered in both TBI and PD datasets.Conclusion: This study underscores the critical role of GPX3 in the molecular intersection of TBI and PD, suggesting it as a novel and potential therapeutic target, offering new insights into potential therapeutic strategies.Keywords: traumatic brain injury, Parkinson’s disease, bioinformatics, oxidative stress, mitochondrial dysfunction, neurodegenerative diseases…”
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72082
Efficacy and safety of fluorescence navigation combined with 3D imaging in precise liver resection: A systematic review and meta-analysis
Published 2025-02-01“…Objective: This study aimed to evaluate the effectiveness and safety of fluorescence navigation combined with three-dimensional imaging (FN&3DI) technology in precise liver resection. Methods: A systematic search was conducted in the PubMed, Web of Science, Embase, and Cochrane Library databases for all English-language publications on fluorescence-guided navigation combined with three-dimensional (3D) imaging technology–assisted precise liver resection, with a cutoff date of July 2024. …”
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72083
Determinants of adherence to the Mediterranean diet among individuals with type 2 diabetes mellitus living in Mediterranean countries: a systematic review
Published 2025-02-01“…BackgroundPatients with type 2 diabetes mellitus (T2DM) are often encouraged to adopt a healthy diet, such as the Mediterranean Diet (MD) yet limited evidence exists about adherence. …”
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72084
A Société Royale de Médecine e as dificuldades na centralização da administração das águas minerais na França
Published 2025-02-01“…O artigo sugere novas leituras sobre o que a histografia tem visto como o fracasso da Société Royale de Médecine na sua tarefa, explicitando a necessidade de uma abordagem que leve em consideração as múltiplas variáveis que moldavam o comércio de águas minerais na França durante as últimas décadas do século XVIII. …”
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72085
Prevalence of Salmonella and Shigella species and their multidrug resistance patterns among pediatric populations in Ethiopia: a systematic review and meta-analysis
Published 2025-01-01“…Result Of a total of 742 identified studies, 89 studies were eligible for full-text analysis. …”
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72086
Transcriptional Targeting of Mature Dendritic Cells with Adenoviral Vectors via a Modular Promoter System for Antigen Expression and Functional Manipulation
Published 2016-01-01“…We selected a 216 bp short Hsp70B′ core promoter induced by a mutated, constitutively active heat shock factor (mHSF) 1 to drive strong gene expression of therapeutic transgenes MelanA, BclxL, and IL-12p70 in HeLa cells, as well as in mature DCs (mDCs). …”
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72087
Impact of Admixtures on Segregation in Self-compacting concrete: A Comparative Study Between Standardized and Ultrasonic Pulse Velocity (UPV) Methods
Published 2024-09-01“… Mastering the rheology of self-compacting concrete (SCC) remains a major challenge for researchers. One of the main obstacles is segregation, an undesirable phenomenon where aggregates separate from the matrix, thus compromising the quality and homogeneity of the material. …”
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72088
Research on failure mechanism of final drive gears of a passenger car based on multi-condition varying-speed accelerated test
Published 2025-02-01“…With this test criteria, a real-vehicle test is conducted to evaluate a trial-manufacture car equipped with a newly developed transmission. …”
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72089
Application of Daftardar Jafari Method to First Grade MHD Squeezing Fluid Flow in a Porous Medium with Slip Boundary Condition
Published 2014-01-01“…In the present work, in the presence of magnetic field and with slip boundary condition, squeezing flow of a Newtonian fluid in a porous medium between two large parallel plates is investigated. …”
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72090
Electroanalytical Performance of a Carbon Paste Electrode Modified by Coffee Husks for the Quantification of Acetaminophen in Quality Control of Commercialized Pharmaceutical Tablets
Published 2016-01-01“…Electrochemical determination of acetaminophen (APAP) was successfully performed using a carbon paste electrode (CPE) modified with coffee husks (CH-CPE). …”
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72091
Genetic and biochemical characterization of a radical SAM enzyme required for post-translational glutamine methylation of methyl-coenzyme M reductase
Published 2025-02-01“…In vitro data show that a B12-dependent radical SAM (rSAM) enzyme, designated MgmA, is responsible for this post-translational modification (PTM). …”
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72092
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72093
Thromboelastography for rapid diagnosis of heparin-like anticoagulant release during anaphylaxis-induced coagulopathy in systemic mastocytosis: a case report
Published 2025-01-01“…Diagnosis and management of anaphylaxis-induced coagulopathy remain challenging. We report a unique case of a 44-year-old man with undiagnosed systemic mastocytosis who developed peanut-induced anaphylactic shock, resulting in cardiac arrest. …”
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72094
Development of Renal Failure without Proteinuria in a Patient with Monoclonal Gammopathy of Undetermined Significance: An Unusual Presentation of AL Kappa Amyloidosis
Published 2012-01-01“…Heavy proteinuria is one of its cardinal manifestations. A 78-year-old man with a 9-year history of IgG kappa light-chain-MGUS and normal urine protein excretion developed severe renal failure. …”
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72095
Šlechta podunajské monarchie a bavorský Řád rytířů sv. Jiří. Případ Eduarda III. Collalto e San Salvatore
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72096
An Experimental Investigation on the Mechanical Properties of Gangue Concrete as a Roadside Support Body Material for Backfilling Gob-Side Entry Retaining
Published 2018-01-01“…Development of a safe and economical roadside support body (RSB) material is the key to successful backfilling gob-side entry retaining (GER). …”
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72097
Evaluating patient outcomes and quality of life following laparoscopic extended totally extraperitoneal repair for ventral hernia: A prospective study
Published 2024-01-01“…Abstract BACKGROUND: Various laparoscopic techniques have been developed for the repair of ventral and incisional hernias. There is a never-ending debate regarding the best procedure for hernia repair. …”
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72098
A Scoping Review of Preferences of Men Who Experienced Sexual Assault: Implications for Adaptation of Trauma-Focused Cognitive Behavioral Therapies
Published 2025-02-01“…Data from included articles were extracted using a systematic extraction grid. A thematic content analysis was conducted to synthesize and present the results from the 37 studies. …”
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72099
Early warning systems (EWSs) for chikungunya, dengue, malaria, yellow fever, and Zika outbreaks: What is the evidence? A scoping review.
Published 2021-09-01“…Included were studies reporting on (a) experiences with existing EWS, including implemented tools; and (b) the development or implementation of EWS in a particular setting. …”
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72100
It is harder for me: A thematic analysis of lived experience of self-care, and its relationship with self-injurious behaviors in psychiatric patients
Published 2025-01-01“…Recognizing the dual role of self-injury—as both a barrier to and a risky form of self-care—may enhance treatment approaches for this population. …”
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