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  1. 66781

    Soil polluted system shapes endophytic fungi communities associated with Arundo donax: a field experiment by Xiaohui Wang, Yao Wang, Yingqiang Sun, Keyi Wang, Junbo Yang, Danjuan Zeng, Ling Mo, Jianxiong Liao, Qianshu Peng, Yu Yao, Gaozhong Pu

    Published 2025-01-01
    “…With the expansion of the mining industry, environmental pollution from microelements (MP) and red mud (RM) has become a pressing issue. While bioremediation offers a cost-effective and sustainable solution, plant growth in these polluted environments remains difficult. …”
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  2. 66782

    Immunogenicity and protective efficacy of a multi-antigenic adenovirus-based vaccine candidate against Mycobacterium tuberculosis by Jin-Seung Yun, Jin-Seung Yun, Eunkyung Shin, Young-Ran Lee, Jung-Ah Lee, Hyeokjin Lee, Jong-Seok Kim, Sung Jae Shin, Sang-Jun Ha, Sang-Won Lee, Dokeun Kim, Jung-Sik Yoo, Hye-Sook Jeong

    Published 2025-01-01
    “…Human adenovirus serotype 5 (Ad5), which induces T-cell response, is a widely used viral vector. In this study, we aimed to evaluate the efficacy of a multi-antigenic recombinant Ad5 vectored vaccine and determine the optimal immunization route for enhanced immune response against Mycobacterium tuberculosis.MethodsWe constructed a multi-antigenic recombinant Ad5 vectored vaccine expressing four antigens (Ag85B-ESAT6-MPT64-Rv2660c) of M. tuberculosis (rAd-TB4), immunized with rAd-TB4 (5 × 107 infectious virus units/mouse) twice at an interval of 4 weeks starting at 10 weeks after BCG priming, and evaluated its boosting efficacy in a BCG-primed mouse model, and determined the optimal immunization route.ResultsCompared with the BCG-only (2 × 105 colony forming units/mouse), subcutaneous injection of rAd-TB4 (1 × 107 infectious virus units/mL; two doses) elicited a T-cell response and cytokine production in lung lymphocytes and splenocytes. rAd-TB4 immunization significantly reduced bacterial loads and inflamed lung areas compared to BCG immunization (p < 0.01) and protected against the H37Rv challenge performed at 17 weeks of BCG priming. …”
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  3. 66783

    From fangs to antidotes: A scoping review on snakebite burden, species, and antivenoms in the Eastern Mediterranean Region. by Ali Alshalah, David J Williams, Alessandra Ferrario

    Published 2024-07-01
    “…Without reliable data, it is difficult to make the case for greater visibility and investment to address the snakebite burden in this Region. A scoping review was therefore conducted to summarize evidence on snake bites in countries of the Eastern Mediterranean.…”
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  4. 66784

    Future Precipitation Projection Based on Multiple Statistical Downscaling Methods — A Case Study of Tibetan Plateau by DONG Qianjin, YUAN Xin

    Published 2024-01-01
    “…Although the Coupled Model Intercomparison Project 6 (CMIP6) can well predict large-scale climatic factors,its effect on projecting watershed scales is still different from the measured data.The error of climate models is even bigger over the Tibetan Plateau,which is a high-altitude region with complicated terrain.Based on the historical scenario of the latest generation of high-resolution CMIP6 model and a variety of future climate emission scenarios such as SSP126,SSP245,SSP370,and SSP585,this paper conducts downscaling analysis and evaluates the projection performance of various statistical downscaling methods such as bias correction,KNN,and SDSM.On this basis,the best statistical downscaling method is used to project future precipitation over the Tibetan Plateau, and the spatial-temporal evolution characteristics of the projected precipitation are analyzed and compared with the historical precipitation over the Tibetan Plateau.The results reveal that the applicability amongst the three statistical downscaling methods in the Tibetan Plateau is large,with the linear regression downscaling method performing the best,followed by the bias correction method and the KNN analogy method.According to the analysis of future precipitation projections,the average precipitation and extreme precipitation over the Tibetan Plateau in the next 80 years will exhibit an overall upward trend,although the rise will be slight,and the spatial distribution will not change much.The results can provide a scientific foundation for the evaluation,planning,and management of water resources on the Tibetan Plateau.…”
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  5. 66785
  6. 66786

    Comparative Analysis of CBCT vs Intraoral Radiography for Interproximal Caries Detection: A Prospective Diagnostic Study by S. Ganesan, Kavitha Ramachandran, Nagaland Tirupati, Arishah Gulzar, H. Cyril Benedict, P. Sai Archana

    Published 2024-12-01
    “…Results: The mean ages of participants in the CBCT and intraoral radiography groups were 35.4 and 34.8 years, respectively, with a balanced gender distribution. High agreement percentages between radiologists and consensus resolutions were observed. …”
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  7. 66787

    Exploring Clec9a in dendritic cell-based tumor immunotherapy for molecular insights and therapeutic potentials by Zubair Hussain, Yueteng Zhang, Lu Qiu, Shanshan Gou, Kangdong Liu

    Published 2025-02-01
    “…This review specifically highlights the C-type lectin receptor family 9 member A (Clec9a or DNGR-1), which is exclusively expressed on cDC1s and plays a pivotal role in augmenting antigen cross-presentation and cytotoxic T lymphocyte (CTL) responses while simultaneously mitigating off-target effects. …”
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  8. 66788

    Metrics used in quality improvement publications addressing environmental sustainability in healthcare: A scoping review protocol. by Colin Sue-Chue-Lam, Sezgi Yanikomeroglu, Doulia Hamad, Brian Wong, Karen Born

    Published 2024-01-01
    “…We propose a scoping review to summarize approaches for selecting and quantifying ecological impacts in the published quality improvement literature. …”
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  9. 66789

    A meta-analysis of risk factors for cardiovascular adverse events with anthracycline based chemotherapy in lymphoma patients by Bo Dai, Jingjing Xu, Baiyan Wang

    Published 2025-01-01
    “…Anthracyclines, hypertension, radiation therapy, diabetes, smoking, age, gender, hyperlipidemia, and obesity were meta-analyzed using a fixed or random effects model. Result Sixteen studies were included in this meta-analysis. …”
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  10. 66790

    City Through the Eyes Of Students' Youth: Assessment and Regional Practices (A Case Study of Nizhny Novgorod) by O. R. Chepyuk, O. Yu. Angelova, S. D. Makarova, N. G. Bryandinskaya, O. V. Petrova

    Published 2024-07-01
    “…The issue of immersing a university in the problems of a city (region) becomes especially relevant in light of global challenges, such as demographic changes, economic instability, and a lack of qualified personnel. …”
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  11. 66791
  12. 66792

    Mycobiota and Natural Incidence of Aflatoxins, Ochratoxin A, and Citrinin in Indian Spices Confirmed by LC-MS/MS by Punam Jeswal, Dhiraj Kumar

    Published 2015-01-01
    “…Nine different Indian spices (red chilli, black pepper, turmeric, coriander, cumin, fennel, caraway, fenugreek, and dry ginger) commonly cultivated and highly used in India were analysed for natural occurrence of toxigenic mycoflora and aflatoxins (AFs), ochratoxin A (OTA), and citrinin (CTN) contamination. Aspergillus flavus and Aspergillus niger were the most dominant species isolated from all types of spices. …”
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  13. 66793

    Género, Ideología, Experiencia y Actitud del profesorado andaluz frente a la formación permanente by Javier Barquín Ruiz, Juan Fernández Sierra

    Published 2002-01-01
    “…La formación permanente del profesorado está sometida en los últimos años a un continuo debate académico, político y social, sin que parezcan encontrarse alternativas efectivas ni suficiente voluntad política para adecuar la preparación y compromiso de los docentes en activo a las nuevas necesidades socioeducativas. …”
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  14. 66794

    Du futur à aujourd’hui, mettre la gestion de l’eau sous tension by Marie-Hélène Vergote, Sandrine Petit

    Published 2020-07-01
    “…This is the case of Tille’s watershed in which a planification of withdrawable volumes has been engaged, to avoid drought’s water restrictions. …”
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  15. 66795

    Developing a Travel Time Estimation Method of Freeway Based on Floating Car Using Random Forests by Juan Cheng, Gen Li, Xianhua Chen

    Published 2019-01-01
    “…To improve the estimation accuracy, a travel time estimation model based on Random Forests is proposed. 7 influence variables are viewed as candidates in this paper. …”
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  16. 66796

    Associations of PM2.5 and its components with term preterm rupture of membranes: a retrospective study by Jiangxia Qin, Weiling Liu, Haidong Zou, Chong Zeng, Cifeng Gao, Weiqi Liu

    Published 2025-01-01
    “…Specifically, the interquartile range (IQR) 3 (IQR3) and IQR4 of ${\mathrm{SO}}_{4}^{2-}$ SO 4 2 − exposure during the third trimester increased the risk of TPROM by 18% (95% CIs [1.01–1.39]) and 18% (95% CIs [1.01–1.39]), respectively. A nonlinear relationship was observed between exposure to PM2.5, ${\mathrm{SO}}_{4}^{2-}$ SO 4 2 − , ${\mathrm{NH}}_{4}^{+}$ NH 4 + , and OM during the second trimester and the risk of TPROM. …”
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  17. 66797
  18. 66798

    Nelson Rodrigues e a censura: o caso Boca de ouro no Arquivo Miroel Silveira by Adriano de Paula Rabelo

    Published 2018-01-01
    “…Este artículo analiza las relaciones entre el dramaturgo Nelson Rodrigues y la censura del estado de São Paulo al inicio de los años 1960, a través de la pieza Boca de oro, tal como estas relaciones están documentadas en el dossier n° 4.906 del Archivo Miroel Silveira, en la Escuela de Comunicaciones y Artes de la Universidad de São Paulo. …”
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  19. 66799
  20. 66800