Straw return combined with water-saving irrigation increases microbial necromass accumulation by accelerating microbial growth-turnover in Mollisols of paddy fields by Peng Chen, Junzeng Xu, Kechun Wang, Zhongxue Zhang, Zhaoqiang Zhou, Yawei Li, Tiecheng Li, Tangzhe Nie, Qi Wei, Linxian Liao

“…Microbial physiology was determined by a substrate-independent H218O labeling method. …”
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Analisis Model Mental Mahasiswa dalam Pengembangan E-Learning Pemrograman Berbasis Gamifikasi Menggunakan Metode Agile UX by Retno Indah Rokhmawati, Fitra Abdurrachman Bachtiar, Fajar Pradana, Kharis Alfian

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Multi-metal mixture exposure and cognitive function in urban older adults: The mediation effects of thyroid hormones by Zhuoqi Zhu, Juanhua Li, Yang Peng, Ning Qin, Jiemei Li, Ying Wei, Biwen Wang, Yunfei Liao, Huaicai Zeng, Lu Cheng, Han Li

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Associations between Children’s Exposure to PM2.5 and their Serum Inflammatory Responses in Taiwan by Wei-Jung Tseng, Jian-He Lu, How-Ran Chao, Ming-Hsien Tsai, Yu-Ting Chang, Liang-Jen Wang, Chih-Cheng Chen, Wan-Nurdiyana-Wan Mansor, Juliana Jalaludin, Chih-Lung Wang, Ying-I Tsai

“…Principal component (PC) analyses revealed a close association between serum MCP-1 and outdoor PM2.5 (Rotated PC2 (RPC2) and percentage of variance = 10.5%), whereas serum IFN-γ, IFN-α2, IL-1b, IL-2, IL-6, IL-10, IL-13, IL-17, and TNF-α were highly correlated (RPC1 and percentage of variance = 45.5%). …”
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Changes in cancer incidence and stage during the COVID-19 pandemic in 2020–2021 in the Nordic countries by Anna Johansson, Anna Skog, Tom Børge Johannesen, Tor Åge Myklebust, Simon M. Kønig, Charlotte Wessel Skovlund, Lina Steinrud Mørch, Søren Friis, Marnar Fríðheim Kristiansen, David Pettersson, Eva María Gudmundsdóttir, Nanna Margrét Kristinsdóttir, Helgi Birgisson, Sandra Irenaeus, Johan Ahlgren, Mats Lambe, Elli Hirvonen, Janne Pitkäniemi, Giske Ursin

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Психоэмоциональное состояние среднего медицинского персонала отделений реанимации и интенсивной терапии при работе с пациентами, инфицированными COVID-19: сравнительное поперечное... by А. Д. Каштанов, Е. В. Карташова, А. А. Галата, В. А. Алиев, Андрей Георгиевич Яворовский, Б. А. Волель, Ю. Л. Васильев, С. С. Ибрахим

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Модуляция метаболизма микробиоты у кардиохирургических пациентов: рандомизированное контролируемое исследование... by М. С. Грекова, Н. В. Белобородова, А. К. Паутова, О. О. Гринь, Т. А. Кабанова, О. В. Дымова, А. А. Еременко, Максим Александрович Бабаев

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Metabolic Risk Factors and Their Impact on Quality of Life in Patients with Pancreatic Cancer, Acute or Exacerbated Chronic Pancreatitis by I. N. Grigor’eva, O. V. Efimova, N. L. Tov, T. S. Suvorova, D. L. Nepomnyashchikh

“…Logistic regression analysis revealed a direct relationship with PC HDL hypocholesterolemia (Exp B = 4.976; p < 0.001) and arterial hypertension (Exp B = 2.742; p = 0.027) and an inverse relationship — with hypercholesterolemia (Exp B = 0.204; p = 0.002). …”
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Editorial by Thomas Duve

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Systematic bias between blinded independent central review and local assessment: literature review and analyses of 76 phase III randomised controlled trials in 45 688 patients with... by Jianrong Zhang, Yu Huang, Hengrui Liang, Wenhua Liang, Jianxing He, Yiyin Zhang, Jiaxi He, Jieyu Wu, Long Jiang, Shiyan Tang, Qihua He, Lindsey Tristine Hamblin, Zhiheng Xu, Yaoqi Chen, Difei Chen, Xinyu Wang, Kexin Deng, Shuhan Jiang, Jiaqing Zhou, Jiaxuan Xu, Xuanzuo Chen

“…Blinded independent central review is usually used as a supplemental or monitor to local assessment but is costly. …”
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Biogenic silver nanoparticles produced by Trichoderma reesei inhibit SARS-CoV-2 infection, reduce lung viral load and ameliorate acute pulmonary inflammation by Marcus V.M.V. Amaral, Cláudia B. Carraro, Amanda C.C. Antoniêto, Mariana N. Costa, Thais F.C. Fraga-Silva, Ualter G. Cipriano, Rodrigo P.F. Abuná, Tamara S. Rodrigues, Ronaldo B. Martins, Andreia M. Luzenti, Glaucia R. Caruso, Priscyla D. Marcato, Vania L.D. Bonato, Dario S. Zamboni, Bergman M. Ribeiro, Sônia N. Báo, Joao S. da Silva, Flávio P. Veras, Roberto N. Silva

“…The COVID-19 pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), posed a significant global health challenge and still demands efforts to develop new therapies. …”
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Potential impact and mechanism of aged polyethylene microplastics on nitrogen assimilation of Lactuca sativa L. by Xiaoli Mou, Hedong Zhu, Renrui Dai, Li Lu, Shengqi Qi, Min Zhu, Yuyang Long, Nan Ma, Chao Chen, Jiali Shentu

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HINT1 suppression protects against age-related cardiac dysfunction by enhancing mitochondrial biogenesis by Michio Sato, Tsuyoshi Kadomatsu, Jun Morinaga, Yuya Kinoshita, Daisuke Torigoe, Haruki Horiguchi, Sumio Ohtsuki, Shuji Yamamura, Ryoko Kusaba, Takanori Yamaguchi, Goro Yoshioka, Kimi Araki, Tomohiko Wakayama, Keishi Miyata, Koichi Node, Yuichi Oike

“…Conclusion: Our findings suggest that mitochondrial biogenesis in cardiomyocytes decreases with age and could underlie cardiac dysfunction, and that the Caren-HINT1-mitochondrial biogenesis axis may constitute a mechanism linking CR to resistance to cardiac aging. …”
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Solid Predominant Histology and High Podoplanin Expression in Cancer-Associated Fibroblast Predict Primary Resistance to Osimertinib in EGFR-Mutated Lung Adenocarcinoma by Yuji Uehara, MD, Hiroki Izumi, MD, PhD, Tetsuro Taki, MD, PhD, Tetsuya Sakai, MD, PhD, Hibiki Udagawa, MD, PhD, Eri Sugiyama, MD, PhD, Shigeki Umemura, MD, PhD, Yoshitaka Zenke, MD, PhD, Shingo Matsumoto, MD, PhD, Kiyotaka Yoh, MD, PhD, Shoko Kubota, MD, PhD, Keiju Aokage, MD, PhD, Naoya Sakamoto, MD, PhD, Shingo Sakashita, MD, PhD, Motohiro Kojima, MD, PhD, Michiko Nagamine, MD, PhD, Yukio Hosomi, MD, PhD, Masahiro Tsuboi, MD, PhD, Koichi Goto, MD, PhD, Genichiro Ishii, MD, PhD

“…Similarly, high-podoplanin (n = 31) versus low-podoplanin (n = 62) expression in CAFs was not associated with worse disease-free survival after surgery (p = 0.65), but was significantly associated with worse PFS and showed a trend towards worse overall survival following osimertinib treatment (p < 0.001, p = 0.11). …”
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Effects of pyrazosulfuron-ethyl on caudal fin regeneration in zebrafish larvae by Chenkai Ge, Zhijun Ye, Weitao Hu, Jingrong Tang, Huimin Li, Fasheng Liu, Xinjun Liao, Jianjun Chen, Shouhua Zhang, Zigang Cao

“…Therefore, we used zebrafish as a model animal to evaluate the effect of the pesticide pyrazosulfuron-ethyl on caudal fin regeneration in zebrafish larvae. …”
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Editorial by Stefan Vogenauer

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تهیه فیلترسلولزی هوا از الیاف بامبو by زهرا کاظمی کرچنگی, نورالدین نظرنژاد, حسن شریفی

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Effects of water flow treatment on muscle quality, nutrient composition and volatile compounds in common carp (Cyprinus carpio) by Lei Wang, Lingran Wang, Chang Liu, Di Feng, Jintai Huang, Zhan Jin, Fangran Ma, Jiaxin Xu, Yuyue Xu, Meng Zhang, Miao Yu, Hongxia Jiang, Zhigang Qiao

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Clinical Utility of Combined Tissue and Plasma Next-Generation Sequencing in Patients With Advanced, Treatment-Naïve NSCLC by Helena Bote-de Cabo, MD, Marco Siringo, MD, Esther Conde, MD, PhD, Susana Hernández, PhD, Fernando López-Ríos, MD, PhD, Alicia Castelo-Loureiro, MD, Esther García-Lorenzo, MD, Javier Baena, MD-PhD, Mercedes Herrera, MD, Ana Belén Enguita, MD, Yolanda Ruano, PhD, Jon Zugazagoitia, MD, PhD, Luis Paz-Ares, MD, PhD

“…We analyzed patient data in two separate cohorts, each assessed with a different plasma-based NGS method: cohort 1 (n = 127, Guardant360), and cohort 2 (n = 148, FoundationACT/FoundationOne Liquid CDx). …”
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