Human-based complex in vitro models: their promise and potential for rare disease therapeutics by Surat Parvatam, Francesca Pistollato, Lindsay J. Marshall, Fabia Furtmann, Devashree Jahagirdar, Mohua Chakraborty Choudhury, Sujata Mohanty, Harshita Mittal, Saveetha Meganathan, Rakesh Mishra

“…Rare diseases affect a small percentage of an individual country’s population; however, with over 7,000 in total, rare diseases represent a significant disease burden impacting up to 10% of the world’s population. …”
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Tumour necrosis factor inhibitors in Ulcerative colitis: real-world data on Therapeutic drug monitoring and evaluation of current treatment targets (STRIDE II) by Jonas Andre Lundekvam, Marte Lie Høivik, Karoline Anisdahl, Milada Cvancarova Småstuen, David J. Warren, Nils Bolstad, Asle Wilhelm Medhus

“…A majority of dosage adjustments were made proactively. …”
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Nutritional Indices, Phytochemistry, and the In Vitro Antioxidant Activity of Carrot Fortified Tomato Concentrate by Olabisi Theresa Ademosun, Abiodun Humphrey Adebayo, Kolawole Oluseyi Ajanaku

“…The plant materials were sourced locally, dried to a uniform weight, and milled using a mechanical blender. …”
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Long-Term Followup Comparing Two Treatment Dosing Strategies of 125I Plaque Radiotherapy in the Management of Small/Medium Posterior Uveal Melanoma by Timothy G. Murray, Arnold M. Markoe, Aaron S. Gold, Fiona Ehlies, Ernesto Bermudez, Andrea Wildner, Azeema Latiff

“…Patients were treated with one of the following two treatment dosing strategies: (1) 85 Gy to the apical height of the tumor (group 1) or (2) 85 Gy to a prescription point of 5.0 mm (group 2). Results. …”
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ارزیابی مصرف انرژی در تولید گندم در گرگان by افشین سلطانی, محمدحسین رجبی, ابراهیم زینلی, الیاس سلطانی

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Instability Mode and Control Technology of Surrounding Rock in Composite Roof Coal Roadway under Multiple Dynamic Pressure Disturbances by Peng Wang, Nong Zhang, Jiaguang Kan, Xingliang Xu, Guangzhen Cui

“…According to the result, it is difficult to form a stable bearing rock beam due to the occurrence characteristics of the weak interlayer of the composite roof. …”
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LPCAT3 regulates the proliferation and metastasis of serous ovarian cancer by modulating arachidonic acid by Fang Wen, Hongjian Ling, Rui Ran, Xinya Li, Houmei Wang, Qianfen Liu, Min Li, Tinghe Yu

“…Results: The expression level of LPCAT3 in serous ovarian cancer tissues was lower than that in other types of ovarian cancer, and high expression was associated with a longer survival time. Overexpressing LPCAT3 reduced cell proliferation, migration and invasion via enhancing ferroptosis and decreasing the survival signaling; these behaviors were enhanced in LPCAT3-downknocked cells, where a higher abundance of arachidonic acid was observed followed by up-regulation of the downstream survival signaling. …”
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La invención del turismo popular: Gran Bretaña, s. XVIII y XIX by John K. Walton

“…Prestamos atención especial al tema de los baños de mar y el desarrollo de las redes de balnearios populares, especialmente cerca de Londres y de los distritos dinámicos industriales, y a los entretenimientos comerciales distintivos que abrían sus puertas en tales sitios. …”
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LIMD1-AS1 promotes the progression of prostate cancer and affects the function of prostate cancer cells by down-regulating miR-29c-3p by Yongsheng Yu, Nan He, Zhaolu Song, Chang Wang, Jinhuang Xu

“…Abstract Purpose Prostate cancer (PCa) is a prevalent and lethal malignancy affecting males, with a considerable proportion of patients experiencing poor survival outcomes. …”
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PMEDM process parameter optimization for machining superalloy MONEL 400 by Abhishek Kumar, Manoj Nikam, T Jagadeesha, Ateekh Ur Rehman, Ajay S Bhongade, Teli Shivagond

“…This research explores powder-mixed electrical discharge machining (PMEDM), a modern technique incorporating conductive metal powders, specifically graphite and silicon, combined with dielectric fluid to improve machining performance. …”
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Sequential Process of Diffusion Bonding and Annealing on Dissimilar Welding of Mg/Al Alloys by Yunlong Ding, Shixue Zhang, Bi Wu, Jinshuang Hao, Yan Chen, Dongying Ju

“…Elemental analysis and structural observation/compound identification were conducted using an electron probe microanalyzer and a scanning electron microscope, respectively. For further assessment of the diffusion zone, microstructural examination was carried out using a transmission electron microscope. …”
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Immunocompatibility of Bacteriophages as Nanomedicines by Tranum Kaur, Nafiseh Nafissi, Olla Wasfi, Katlyn Sheldon, Shawn Wettig, Roderick Slavcev

“…Recently, phages have been employed as gene-delivery vectors (phage nanomedicine), for nearly half a century as tools in genetic research, for about two decades as tools for the discovery of specific target-binding proteins and peptides, and for almost a decade as tools for vaccine development. …”
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Hemşirelik Öğrencilerinde E-Sağlık Okuryazarlığı ve Siberkondri İlişkisi by Türkmen Kübra İnanlı, Ahsen Taştan Gürkan, Afitap Özdelikara

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Dysregulation of Kisspeptin and Leptin, as Anorexigenic Agents, Plays Role in the Development of Obesity in Postmenopausal Women by Andon Hestiantoro, Brilliant P. K. Astuti, Raden Muharam, Gita Pratama, Fiastuti Witjaksono, Budi Wiweko

“…During the menopausal period, women have a higher tendency to develop obesity and any other metabolic syndromes. …”
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GAMBARAN STATUS HIDRASI DAN JENIS MINUMAN SAAT BEROLAHRAGA PADA ATLET BASKET REMAJA by Nurul Ichsania, Nurussyariah Hammado, Andi Febi Irawati

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Numerical simulation with hyperelastic constitutive model for high-performance multifilaments used in offshore mooring ropes by Daniel Magalhães da Cruz, Tales Luiz Popiolek Júnior, Marcelo de Ávila Barreto, Stephane Pires de Souza, Larissa Basei Zangalli, Aleones José da Cruz Júnior, Taline Carvalho Martins, Ana Lúcia Nazareth da Silva, Ivan Napoleão Bastos, Carlos Eduardo Marcos Guilherme

“…There was a certain difficulty in representing the behavior when many inelastic components were present in the fibers. …”
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Evaluating the therapeutic communication skills of nursing students in the clinical setting: The experiences of students, patients and patients’ relatives by Neşe Mercan, Sevinç Mersin

“…The mean score for non-Therapeutic Communication Skills (warning, downplaying emotions, advising, vague reassurance/cliché response, changing the subject, defending, and judging) was 18.59 ± 7.60. As a result of the analysis of the qualitative data, three main themes emerged: “challenges in mastering and applying therapeutic communication”, “the positive impact of therapeutic communication”, and the “patients' and relatives’ views of the nursing students' communication skills”. …”
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Physics Informed Neural Networks for Modeling Large-Scale Wind Driven Ocean Circulation by Boohyun An, Mohammad Z. Shanti, Chan Yeob Yeun, Ernesto Damiani, Sungmun Lee, Tae-Yeon Kim

“…This study investigates the application of the physics informed neural network as a meshfree collocation method for approximating solutions to large-scale wind driven ocean circulation models. …”
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Innovative fertilization strategies for in-situ pollution control and carbon negativity enhancement in agriculture by Ya-Zhen Huang, You-Yi Lee, Chihhao Fan

“…The washed-away phosphate demonstrated a different trend because adding microbial agents, including phosphorus-solubilizing bacteria, converted fixed inorganic phosphorus in the soil into water-soluble phosphorus. …”
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Controls of lithology and climate over chemical weathering trends: new insights from the precipitation-dominated Dokriani glacier, central Himalaya, India by Shipika Sundriyal, Tanuj Shukla, Shichang Kang, Yulan Zhang, Dwarika Prasad Dobhal, Rajesh Singh

“…The chemical composition of meltwater-draining Himalayan glacierized basins reflects the dominance of carbonic acid in weathering of silicate and carbonate minerals, yet the role of sulfuric acid-mediated reactions in the mineral weathering and ionic release is still unclear. Here, we present a long-term study (1992–2018) of chemical weathering characteristics of a precipitation-dominated glacierized basin (Dokriani glacier) of central Himalaya. …”
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