Novel histone deacetylase-5 inhibitor T2943 exerts an anti-depressive effect in mice by enhancing GRID1 expression by Juan Du, Ruyun Liu, Lin Ma, Yue Liu, Wei Wei, Ning Liu, Qiuhua Cao, Jianqiang Yu

“…We previously identified a novel HDAC5 inhibitor, T2943, with antidepressant properties that promote histone 3 lysine-14 acetylation (H3K14ac) by inhibiting HDAC5 activity. …”
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Dipeptidyl-Peptidase 4 Inhibitor Sitagliptin Ameliorates Hepatic Insulin Resistance by Modulating Inflammation and Autophagy in ob/ob Mice by Wenbin Zheng, Jing Zhou, Shasha Song, Wen Kong, Wenfang Xia, Lulu Chen, Tianshu Zeng

“…In the current study, ob/ob mice, a mouse model of genetic obesity and diabetes, were administered via gavage with sitagliptin 50 mg/kg daily for 4 weeks. …”
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Relationships of dermatologic symptoms and quality of life in patients with psoriatic arthritis: analysis of two tofacitinib phase III studies by Peter C. Taylor, Andrew G. Bushmakin, Joseph C. Cappelleri, Pamela Young, Rebecca Germino, Joseph F. Merola, Gil Yosipovitch

“…Rheumatologists should be aware of dermatologic manifestations and QoL impacts in patients with PsA.ClinicalTrials.gov NCT01877668; NCT01882439…”
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Enhancing Disaster Situation Awareness Through Multimodal Social Media Data: Evidence from Typhoon Haikui by Songfeng Gao, Tengfei Yang, Yuning Xu, Naixia Mou, Xiaodong Wang, Hao Huang

“…However, social media platforms, as a vital source of social sensing, offer significant potential to supplement disaster situational awareness. …”
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Prefrontal cortex neuronal ensembles dynamically encode task features during associative memory and virtual navigation by Mohamad Abbass, Benjamin Corrigan, Renée Johnston, Roberto Gulli, Adam Sachs, Jonathan C. Lau, Julio Martinez-Trujillo

“…Here, we show that, during a virtual reality task with naturalistic elements that requires associative memory, individual neurons and neuronal ensembles in the primate LPFC dynamically mix unconstrained features of the task, such as eye movements, with task-related visual features. …”
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In Vitro Study on the Antioxidant Potentials of the Leaves and Fruits of Nauclea latifolia by Ademola O. Ayeleso, Oluwafemi O. Oguntibeju, Nicole L. Brooks

“…This study was carried out to investigate the in vitro antioxidant potentials of the leaves and fruits of Nauclea latifolia, a straggling shrub or small tree, native to tropical Africa and Asia. …”
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The influence of gender and waist circumference in the association of body fat with cardiometabolic diseases by Milad Bagheri, Mehran Nouri, Ali Kohanmoo, Reza Homayounfar, Masoumeh Akhlaghi

“…Results Cardiometabolic risk factors (body mass index, waist circumference, blood pressure, blood glucose and lipids) had an inverse association with BF% tertiles in both sexes. Women had a higher BF% and prevalence of metabolic diseases than men, but men demonstrated stronger associations between BF% and cardiometabolic diseases. …”
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The impact of drinking on smoking cessation outcomes among Hong Kong Chinese youth smokers by Ka Yan Ho, Katherine Ka Wai Lam, Qi Liu, Ting Mao, Funa Yang, Mulualem Getaneh Belay, Cynthia Sau Ting Wu, Mak Yim Wah

“…Drinking is a common unhealthy behaviour among youth smokers aged 25 or below. …”
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Novel cycloviruses identified by mining human blood metagenomic data show close relationship to those from animals by Yuanqing Wang, Yuanqing Wang, Xiaojie Jiang, Yuan Xi, Siqi Wei, Songyi Ning, Wen Zhang, Wen Zhang

“…These proteins are crucial for viral replication and host-cell interaction: the Rep protein is involved in initiating viral genome replication, while the Capsid protein plays a key role in the assembly of new virions and the virus's ability to interact with host immune systems. …”
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An In-Vitro Comparison of Effects of Passive Ultrasonic Irrigation with Various Concentrations of Peracetic Acid, Citric Acid, Sodium Hypochlorite, and Ethylene Diamine Tetra Aceti... by Manjula Srinivas Pandurangan, Bandlapally Sreenivasa Guptha Anila, Roopadevi Garlapati, Niharika Halder, Mayana Aameena Banu, Lavanya Modala

“…Introduction: Bacteria play a key role in pulp and periapical disease, making their complete removal essential in endodontic treatment. …”
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Statistical analysis of heat waves in the southern slopes of Alborz by Zienab Hosinpoor, AliAkbar Shamsipour, Mostafa Karimi, Faramarz khoshakhlagh

“…Heat waves are important phenomena in Iran, And its upsurge in recent years seems to have a high upside trend.This climate has a negative impact on agriculture, forest fire and forestry, water resources, energy use and human health.The purpose of the research is to explain the frequency, time distribution, continuity of thermal waves, and the identification of its occurrence in the southern foothills of central Alborz.Therefore, using the statistical methods and maximum daily temperature data of Tehran (Mehrabad), Qazvin and Semnan stations for the statistical period of 30 years (1966-2016), the mentioned characteristics were extracted.In the first step, the nonparametric method of Kendal was used to understand the variability and awareness of the monthly trend of maximum temperatures in the study period.In order to determine the severity, duration and frequency of heat wave events, the percentiles (95.98) and normalized temperature deviation (NTD) were used.The results of the study showed that the frequency of short-wave heat waves was higher.Most frequencies are related to 2-day waves, respectively, and Tehran (Mehrabad), Semnan and Qazvin stations are more frequent.The highest frequency of annual events was detected at stations in Tehran (11 waves in 2010), in Semnan (9 waves in 2015) and Qazvin (7 waves in 2015), respectively.The highest frequency of monthly heat wave events was recorded in June and September.The highest continuation (15 days) was obtained in March 2008 with the percentile method at Mehrabad station.In the normalized deviation method, the temperature was calculated as a warm wave (12 days) in 2008.The highest annual frequency of heat loss occurred in all three stations in 2015.The evolution of the process indicated an increase in the incidence of thermal waves in the cold period of the year But in other chapters, no meaningful changes were made.As it says, the decline in cold winter temperatures is on the southern slopes of Alborz.The results of the two methods showed that in the normalized deviation of the temperature, the number of thermal waves more than the percentile method was recorded, but in the percentile method, the thermal wave was more prominent in the cold period of the year.…”
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Comparative Analysis of Spontaneous and Stimulus-Evoked Calcium Transients in Proliferating and Differentiating Human Midbrain-Derived Stem Cells by Torben Johansen, Christina Krabbe, Sissel Ida Schmidt, Alberto Martínez Serrano, Morten Meyer

“…Spontaneous calcium transients were detected in a large fraction of both proliferating (>50%) and differentiating (>55%) cells. …”
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СИНТЕЗ И ИССЛЕДОВАНИЕ ОПТИЧЕСКИХ СВОЙСТВ ГАЛЛАТА ЕВРОПИЯ ПЕРОВСКИТНОЙ СТРУКТУРЫ by Владимир Антонович Новоженов, Владимир Петрович Смагин, Анастасия Борисовна Рошколаева, Наталья Егоровна Стручева, Лина Викторовна Затонская

“…Pbnm, параметры кристаллической решетки: a = 0,5000 нм, b = 0,7565 нм, c = 0,5213 нм). В спектре люминесценции EuGaO3 зарегистрирована серия характеристичных для ионов Eu3+ узких полос, связанных с 5D0 → 7Fj переходами 4f-электронов. …”
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Challenging Gender Norms: Male Physicians' Perspectives on Family Planning in Rural Islamabad by Junaid Jamshed, Rida Shakil, Muhammad Hassan Laique

“…The interviews explored their experiences and perceptions of engaging in FP service provision, a field predominantly led by female healthcare providers due to cultural norms and gendered divisions in healthcare roles. …”
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Effect Of Zinc And Ingredients Of Protein Supplement On Sperm Parameters And Male Reproductive Hormones- An RCT Study by Saira Safdar, Irfan Afzal Mughal, Noor Ul Ain, Sidra Jabeen, Muhammad Hassaan Farooq, Asma Irfan

“…Mean ± SEM of serum level of testosterone Hormone, Follicle Stimulating Hormone(FSH), and Luteinizing Hormone(LH) of Group 2 rats showed a significant (P<0.05) decrease when compared with Group 1 rats. …”
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INTELLIGENT TECHNOLOGY FOR SEMANTIC COMPLETENESS ASSESSMENT OF BUSINESS PROCESS MODELS by Oleksandr Rudskyi, Andrii Kopp, Tetiana Goncharenko, Igor Gamayun

“…In this paper, we present a method for comparing business process models with their textual descriptions, using a semantic-based approach based on the SBERT (Sentence-Bidirectional Encoder Representations from Transformers) model. …”
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Caracterización de la salud bucodental en gestantes del Área II del municipio Cienfuegos by Darai Bárbara Sánchez Montero, Zoraida Montero Padrón, Yahima Pons López

“…Los datos se obtuvieron a partir de la entrevista personal y análisis de documentos como historia clínica individual y encuestas de salud bucodental. …”
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Nuevo sistema robótico social de rehabilitación de pacientes pediátricos con parálisis cerebral by Mauro Tassinari-Lagos, Pablo Romero-Sorozábal, Carlos Martín, Dolores Blanco, María Malfaz, Eduardo Rocon

“…Este estudio se enfoca en las terapias de rehabilitación robóticas, llevadas a cabo con la plataforma CPWalker, para la realización de ejercicios funcionales mediante movimientos precisos. …”
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Dynamics of Land Use, Land Cover Changes and Their Impacts on Land Surface Temperature Using Satellite Imagery by Temesghen E. Sereke, Tumuzghi Tesfay, Vitaly V. Bratkov, Elsayed S. Mohamed, Dinh T. Quyen

“…Two Landsat-7 ETM and One Landsat OLI_TRI-8 images from 2002, 2012 and 2022 were utilized. A supervised vector machine algorithm was used to classify LULC. …”
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Optimal integration of photovoltaic sources and capacitor banks considering irradiance, temperature, and load changes in electric distribution system by Khaled Fettah, Ahmed Salhi, Talal Guia, Abdelaziz Salah Saidi, Abir Betka, Madjid Teguar, Hisham Alharbi, Sherif S. M. Ghoneim, Takele Ferede Agajie, Ramy N. R. Ghaly

“…By effectively combining PVRES and CBs, this research highlights a robust approach to enhancing both technical performance and operational reliability in distribution systems. …”
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