<i>Musa paradisiaca</i> L. Inflorescence Abrogates Neutrophil Activation by Downregulating TLR4/NF-KB Signaling Pathway in LPS-Induced Acute Lung Injury Model by Francisco Allysson Assis Ferreira Gadelha, Raquel Fragoso Pereira Cavalcanti, Cosmo Isaias Duvirgens Vieira, Joao Batista De Oliveira, Louíse Mangueira De Lima, Adriano Francisco Alves, Matheus Marley Bezerra Pessoa, Leônia Maria Batista, Naiara Naiana Dejani, Marcia Regina Piuvezam

“…<i>Musa paradisiaca</i> L. (banana) is a cosmopolitan plant, and homemade syrup from its inflorescence is used in many countries to treat pulmonary inflammation. …”
Get full text

Dentin-Derived Inorganic Minerals Promote the Osteogenesis of Bone Marrow-Derived Mesenchymal Stem Cells: Potential Applications for Bone Regeneration by Gang Lei, Yanqiu Wang, Yan Yu, Zehan Li, Jiamin Lu, Xingyun Ge, Na Li, Ana Gloria Cuba Manduca, Jinhua Yu

“…BMMSCs cultured with DIM presented a higher level of osteogenic differentiation ability than those in the control group. …”
Get full text

Oxaliplatin-Loaded Chitosan Nanoparticles Decorated with Cetuximab Single-Chain Variable Fragment for Human Colorectal Cancer Treatment by Khadijeh Falahzadeh, Fariba Esmaeili, Leila Nematollahi, Elham Bayat, Mehdi Khoobi, Mohammadali Mazloomi, Masumeh Jalalvand, Reza Faridi Majidi, Babak Negahdari

“…Engineeredbiomolecules can be used as a targeted tool to deliver drugs directly to tumors that reduce the adverse effects of conventionaltreatments. …”
Get full text

Sepsis in Internal Medicine: blood culture-based subtypes, hospital outcomes, and predictive biomarkers by Gaetano Zizzo, Gabriele Guazzardi, Daniela Bompane, Francesco Di Terlizzi, Giorgio Rotola, Ilario Stefani, Michela Medugno, Mario Bucalo, Antonino Mazzone

“…BackgroundSepsis is a challenging condition increasingly managed in medical wards, however literature and clinical evidence in this hospital setting are lacking.MethodsUsing the computational i2b2 framework, we retrospectively analyzed data from patients admitted to internal medicine units of four hospitals in Lombardy (Italy) between January 2012 and December 2023, with a discharge diagnosis of sepsis, septic shock, or septicemia.ResultsA total of 4,375 patients were recruited. …”
Get full text

Impact of religious fasting on ocular dryness: objective and subjective assessment by Amal F. Alomari, Sara Issa, Asma Musleh, Mohammad Abusamak, Mohammad Abusamak, Omar Bdair, Omar Bdair, Saif Aldeen AlRyalat, Saif Aldeen AlRyalat, Alanoud Al-Wakfi, Mohammed Jaber, Ahmad Alloubani, Haitham Sahawneh, Haitham Sahawneh, Muhannd El-Faouri, Ayman Abdul Aziz, Muawyah Al Bdour

“…Ocular Surface Disease Index (OSDI) was evaluated at each timepoint to assess dryness symptoms subjectively.ResultsThis study included a total of 40 patients. NIKBUT values during the fasting times were higher than during the non-fasting times; however, the difference was statistically non-significant. …”
Get full text

Composite coatings of S-HA nanoparticles and Schiff base on ZE21B alloy for stronger corrosion resistance and biological performance by Zhonghua Xue, Xiaojing Sun, Hang Li, Mujahid Iqbal, Liujie Qi, Fei Wang, Yachen Hou, Jingan Li, Shaokang Guan

“…In order to prolong the service time and enhance the biocompatibility of magnesium (Mg) alloys used for cardiovascular scaffolds, the composite coatings of Schiff base (corrosion inhibitor) and sulfonated hyaluronic acid (S-HA) nanoparticles (NP@S-HA) with different sulfur content (10.02 wt% and 11.55wt%) were prepared on ZE21B alloy by means of electrostatic spraying with spraying time of 0.5 min, 1.0 min and 1.5 min in this paper. Through a series of representations including corrosion experiments and biological characterization, the composite coatings with a sulfur content of 11.55wt% and a spray time of 1.0 min were finally picked due to its better comprehensive performances, which provides a new possibility for the surface modification of degradable Mg alloy cardiovascular scaffolds.…”
Get full text

Six-Gene Signature Associated with Immune Cells in the Progression of Atherosclerosis Discovered by Comprehensive Bioinformatics Analyses by Bin Zhao, Dan Wang, Yanling Liu, Xiaohong Zhang, Zheng Wan, Jinling Wang, Ting Su, Linshan Duan, Yan Wang, Yuehua Zhang, Yilin Zhao

“…Background. As a multifaceted disease, atherosclerosis is often characterized by the formation and accumulation of plaque anchored to the inner wall of the arteries and causes some cardiovascular diseases and vascular embolism. …”
Get full text

Comparing clinical only and combined clinical laboratory models for ECPR outcomes in refractory cardiac arrest by Chun-Chieh Chiu, Yu-Jun Chang, Chun-Wen Chiu, Ying-Chen Chen, Yung-Kun Hsieh, Shun-Wen Hsiao, Hsu-Heng Yen, Fu-Yuan Siao

“…This study aims to compare a simpler clinical-only model with a model that includes both clinical and pre-ECMO laboratory parameters, to refine patient selection and improve ECPR outcomes. …”
Get full text

Peningkatan Performa Ensemble Learning pada Segmentasi Semantik Gambar dengan Teknik Oversampling untuk Class Imbalance by Arie Nugroho, M. Arief Soeleman, Ricardus Anggi Pramunendar, Affandy Affandy, Aris Nurhindarto

“…Image segmentation is one of the fields in computer vision that discusses how computers learn and recognize segments of an image according to specified labels. In reality, a lot of data has unbalanced classes or labels, of course, it will affect the accuracy of a prediction. …”
Get full text

The association between serum fructosamine and random spot urine fructose levels with the severity of non-alcoholic fatty liver disease – an analytical cross-sectional study by H Kamuzinzi, M Kgomo, P Rheeder, N Dada, P Bester

“…Our setting requires a reasonable approach to screen for and aid the diagnosis of NAFLD. …”
Get full text

Exendin-4 Exacerbates Burn-Induced Morbidity in Mice by Activation of the Sympathetic Nervous System by Xiao-Jing Ji, Ji-Wei Hao, Guang-Lei Li, Ning Dong, Xin-Qi Wang, Min Zhou, Qing-Hong Zhang, Yong-Ming Yao

“…We hypothesize that exendin-4, a GLP-1 analogue, might affect the immune response via the activation of the sympathetic nervous system in burn injury. …”
Get full text

Fundamentals of bio-based technologies for selective metal recovery from bio-leachates and liquid waste streams by Anna Sieber, Sabine Spiess, Wadih Y. Rassy, Wadih Y. Rassy, Dominik Schild, Thomas Rieß, Shalini Singh, Rohan Jain, Nora Schönberger, Franziska Lederer, Klemens Kremser, Klemens Kremser, Georg M. Guebitz, Georg M. Guebitz

“…Single metal solutions or mixtures with a low complexity have been the focus of previous studies and reviews, but this does not reflect the nature of complex industrial effluents. …”
Get full text

Integrating transcriptomics, metabolomics, and network pharmacology to investigate multi-target effects of sporoderm-broken spores of Ganoderma lucidum on improving HFD-induced dia... by Lidan Hu, Lili Yu, Zhongkai Cao, Yue Wang, Caifeng Zhu, Yayu Li, Jiazhen Yin, Zhichao Ma, Xuelin He, Ying Zhang, Wunan Huang, Yuelin Guan, Yue Chen, Xue Li, Xiangjun Chen

“…Diabetes mellitus (DM) is a major metabolic disease endangering global health, with diabetic nephropathy (DN) as a primary complication lacking curative therapy. …”
Get full text

The use and subjective experience of sleep apps and their relationship with personality characteristics among young adults by Ståle Pallesen, Ståle Pallesen, Øystein Vedaa, Øystein Vedaa, Erlend Sunde, Erlend Sunde, Anette Harris, Siri Waage, Siri Waage, Ingvild West Saxvig, Jiewen Zhang, Bjørn Bjorvatn, Bjørn Bjorvatn

“…Still, understanding of characteristics of users and the impact of sleep app usage remains limited.MethodsA sample of 940 young adults (18–30 years) living in the UK were recruited from Prolific (online research platform offering researchers access to survey panels) and invited to participate in a survey on the use and experience with sleep apps. …”
Get full text

Estimation Model for Cotton Canopy Structure Parameters Based on Spectral Vegetation Index by Yaqin Qi, Xi Chen, Zhengchao Chen, Xin Zhang, Congju Shen, Yan Chen, Yuanying Peng, Bing Chen, Qiong Wang, Taijie Liu, Hao Zhang

“…The spectral vegetation indices derived from remote sensing data provide a detailed spectral analysis for assessing vegetation characteristics. …”
Get full text

An exploratory study on the differential diagnostic indicators between adult systemic EBV-positive T-cell lymphoproliferative disorders and angioimmunoblastic T-cell lymphoma with... by Xiaodan Zheng, Yuanyuan Zheng, Yanlin Zhang, Jianlan Xie, Xiaojing Teng, Kuo Bi, Lan Sun, Xiaowen Huang, Mulan Jin, Xiaoge Zhou

“…Abstract Background The differential diagnosis between adult systemic EBV-positive T-cell lymphoproliferative disorders (EBV+ T-LPD) and angioimmunoblastic T-cell lymphoma (AITL) with multiple EBV infections is difficult, and distinguishing between the two has become a diagnostic challenge for pathologists. Given that the clinical treatment plans are different, an accurate diagnosis is a prerequisite to ensure effective treatment, therefore, it is extremely necessary and meaningful to find effective pathological indicators for distinguishing between two diseases. …”
Get full text

Prognostic Prediction Value of qSOFA, SOFA, and Admission Lactate in Septic Patients with Community-Acquired Pneumonia in Emergency Department by Haijiang Zhou, Tianfei Lan, Shubin Guo

“…Community-acquired pneumonia (CAP) is a leading cause of sepsis and common presentation to emergency department (ED) with a high mortality rate. …”
Get full text

Targeting adipocyte ESRRA promotes osteogenesis and vascular formation in adipocyte-rich bone marrow by Tongling Huang, Zhaocheng Lu, Zihui Wang, Lixin Cheng, Lu Gao, Jun Gao, Ning Zhang, Chang-An Geng, Xiaoli Zhao, Huaiyu Wang, Chi-Wai Wong, Kelvin W. K. Yeung, Haobo Pan, William Weijia Lu, Min Guan

“…Estrogen-related receptor α (ESRRA) is a key regulator responding to metabolic stress. …”
Get full text

Comportamiento de la mortalidad según necropsia en Servicios de Medicina Interna y Geriatría de Cienfuegos by Ana Laura Navarro Baldellot, Laidamy Rodríguez Amador, Roine Alberto Pena Olivera, Héctor Javier Cruz de los Santos, Lisanka Fumero Roldán, Samuel Sánchez Sánchez

“…<strong><br />Métodos:</strong> se realizó un estudio descriptivo-retrospectivo de serie de casos, de los 730 pacientes fallecidos a los que se les practicó necropsia entre enero de 2017 y diciembre de 2019. …”
Get full text

妊娠期糖尿病孕妇产后糖尿病发生的高危因子分析 by 李璐, 徐安平, 夏勇, 纪玲

“…临床上应对这类孕妇的血糖进行动态的监 控，及时发现并纠正2 h血糖和HbA1c值的异常。…”
Get full text