Gender-Specific Hippocampal Dysrhythmia and Aberrant Hippocampal and Cortical Excitability in the APPswePS1dE9 Model of Alzheimer’s Disease by Anna Papazoglou, Julien Soos, Andreas Lundt, Carola Wormuth, Varun Raj Ginde, Ralf Müller, Christina Henseler, Karl Broich, Kan Xie, Dan Ehninger, Britta Haenisch, Marco Weiergräber

“…Alzheimer’s disease (AD) is a multifactorial disorder leading to progressive memory loss and eventually death. …”
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Randomized Clinical Trial of Intraocular Pressure-Lowering Medications on Preventing Spikes in Intraocular Pressure Following Intravitreal Anti-Vascular Endothelial Growth Factor I... by Piriya Soomsawasdi, Kulawan Rojananuangnit, Eakkachai Arayangkoon, Ratchada Chantiwas, Sureeporn Pengrungreungwong, Nontakorn Preawsampran, Natnaree Tinpowong, Rujira Samakhararaksakul, Kanokwan Katkingkaew, Natthapuch Seekhum, Wanwisa Sathim

“…Abstract Introduction Intravitreal injections of anti-vascular endothelial growth factor (anti-VEGF) agents are a primary management option for retinal diseases. …”
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靶向调控非小细胞肺癌的作用机制 by 谢传华, 陈海龙, 黄萍, 郭守俊, 邱伊连, 王硕, 潘宜云, 胡志苹

“…【目的】探究miR-204-3p 靶向EphB2 基因对非小细胞肺癌增殖、凋亡、侵袭的调控机制。【方法】培养将非小细胞肺癌A549 细胞系分为 5 组 NC mimic 组（miR-204-3p 过表达阴性对照组）、miR-204-3p mimic 组（miR-204-3p 过表达组）、oe-NC 组（EphB2 过表达阴性对照组）、oe-EphB2 组（EphB2 过表达组）、miR-204-3p mimic+oe-EphB2 组（miR-204-3p 与EphB2 均过表达组）。…”
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Deciphering Immunometabolic Landscape in Rheumatoid Arthritis: Integrative Multiomics, Explainable Machine Learning and Experimental Validation by Dong Q, Wu J, Zhang H, Chen X, Xu X, Chen J, Shi C, Luo L, Zhang D

“…Explainable machine learning, PPI network analysis, and qPCR jointly identified four hub genes (PFN1, SRP14, S100A11, and SAP18). CMAP, molecular docking, and PheWAS analysis further highlighted vismodegib as a promising therapeutic candidate.Conclusion: This study clarifies the key immunometabolic mechanisms in RA, pinpointing promising paths for better prevention, diagnosis, and treatment.Keywords: rheumatoid arthritis, dendritic cells, single-cell sequencing, bulk transcriptome, explainable machine learning, drug repositioning…”
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Molecular mechanisms of cis-oxygen bridge neonicotinoids to Apis mellifera Linnaeus chemosensory protein: Surface plasmon resonance, multiple spectroscopy techniques, and molecular... by Xiangshuai Li, Shiyu Li, Yang Liu, Li Cui, Daibin Yang, Shuning Chen, Xusheng Shao, Huizhu Yuan, Xiaojing Yan

“…Honeybees, essential pollinators for maintaining biodiversity, are experiencing a sharp population decline, which has become a pressing environmental concern. …”
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Functionality of bacterial communities in constructed wetlands used for water purification: influence of root components and seasonality by Yao Huang, Yao Huang, Weili An, Weili An, Tianzhu Ning, Zhiguang Ma, Yuelin Li, Ke Liu, Lingbo Ji, Lingbo Ji, Hongxiao Liu, Dafeng Hui, Hai Ren

“…The abundance and diversity of bacterial communities exhibited a decline from the rhizosphere to the endosphere, accompanied by an increase in the number of distinctive biomarkers from the rhizosphere to the endosphere. …”
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Circular RNA RHOT1 Regulates miR-142-5p/CCND1 to Participate in Chondrocyte Autophagy and Proliferation in Osteoarthritis by Gu Man, Haiwen Yang, Kai Shen, Donghong Zhang, Julin Zhang, Hao Wu, Hongyu Zhang, Jinhuan Wang

“…Meanwhile, cyclinD1 (CCND1) is a key cell cycle regulatory protein and plays a crucial role in OA progression. …”
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Mitochondrial Gene Expression of Three Different Dragonflies Under the Stress of Chlorpyrifos by Yuxin Chen, Ziwen Yang, Zhiqiang Guo, Lemei Zhan, Kenneth B. Storey, Danna Yu, Jiayong Zhang

“…The present study quantified the transcript levels of mitochondria protein-coding genes (mtPCGs) using quantitative real-time polymerase chain reaction (<i>RT-qPCR</i>) in samples of larvae of three dragonfly species (<i>A. parthenope</i>, <i>E. elegans</i>, and <i>G. confluens</i>) under different levels of CPF stress. …”
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Reverse Osmosis Coupled with Ozonation for Clean Water Recovery from an Industrial Effluent: Technical and Economic Analyses by Ivette Montero-Guadarrama, Claudia Muro Urista, Gabriela Roa-Morales, Edith Erialia Gutiérrez Segura, Vianney Díaz-Blancas, Germán Eduardo Dévora-Isiordia, Jesús Álvarez-Sánchez

“…According to the effluent conditions, a coupled process, integrated with ozonation and reverse osmosis, was indicated to be a treatment for water recovery. …”
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Clinical efficacy and hemodynamic effects of levosimendan in cardiac surgery patients after surgery by Meiling Zhao, Yunfeng Hou, Meng Yuan, Shuang Ma, Yifeng Yue

“…Eighty cases each were assigned to the research and control groups using a random number table. Document the general patient data for each of the two groups; compare the clinical outcomes of the two groups. …”
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Dosimetry of automatic non-coplanar volumetric-modulated arc therapy for nasopharyngeal carcinoma by Kaiqiang Chen, Jihong Chen, Yanming Cheng, Danni Hong, Cairong Hu, Penggang Bai, Jinyong Lin, Yang Yang, Xiuchun Zhang

“…Compared with the TOMO plans, the HA plans exhibited a steeper dose fall-off for PTV69.75Gy (P ​< ​0.05). …”
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Epidemiological survey on tick borne diseases of pet dogs in korla, northwestern china by Jianhui CHEN, Shen SHI 2, Nannan CUI, Lixin SU, Ziqi WANG, Fang LI, Shang ZHAN, Guoyu ZHAO, Yuanzhi WANG, Xijiang WANG

“…Pet dogs pose a potential risk to transmitting zoonotic pathogens by ticks. …”
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Heat Tolerance Differences Between Hu Sheep and Hu Crossbred Sheep in Microbial Community Structure and Metabolism by Jing-Da Yuan, Li-Wei Wang, Shao-Yin Fu, Ri-Ge-Li-Tu E, Xiao-Qi Ren, Hua Sun, Fang Liu, Biao Wang, Jiang-Hong An, Meng-Ran Zhao, Jiang-Feng He, Xiao-Long He

“…Metabolomic results showed that, compared to Hu sheep, Xinggao sheep exhibited higher cortisol (COR) and dopamine (DA) levels under heat stress conditions, a stronger lipid mobilization capacity, and elevated levels of tricarboxylic acid (TCA) cycle-related metabolites. …”
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Application of optical coherence tomography angiography to study retinal and choroidal vascular changes in patients with first-time coronary artery stenosis by Rongrong Guan, Shuyan Qin, Yezhu Chi, Zhen Tang, Haiyang Liu

“…FAZ perimeter is a risk factor for predicting the occurrence of coronary artery stenosis.…”
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On-chip integrated plasmon-induced high-performance self-powered Pt/GaN ultraviolet photodetector by Tong Xu, Shulin Sha, Kai Tang, Xuefeng Fan, Jinguo Liu, Caixia Kan, Gangyi Zhu, Feifei Qin, Daning Shi, Mingming Jiang

“…When illuminated upon ultraviolet light at 0 V bias, the Pt/GaN device exhibits significant photovoltaic performances, including a peak responsivity of 200.1 mA W−1, external quantum efficiency of 65%, and other figures-of-merit. …”
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Genotype-Phenotype Correlation of G6PD Mutations among Central Thai Children with G6PD Deficiency by Boonchai Boonyawat, Tim Phetthong, Nithipun Suksumek, Chanchai Traivaree

“…A total of 102 children including 73 males (71.6%) and 29 females (28.4%) were included in our study. …”
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Exploring Health Educational Interventions for Children With Congenital Heart Disease: Scoping Review by Neda Barbazi, Ji Youn Shin, Gurumurthy Hiremath, Carlye Anne Lauff

“…Despite advances in medical care, CHD is often a chronic condition requiring continuous management and education. …”
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Comparison of the effect of ranibizumab in retinal vein occlusion and macular edema with different optical coherence tomographic patterns by Yue Xu, Yue-Cong Yin, Ze-Yu Song, Xiao-Yu Zhou, Jia-Ju Zhang, Juan Liang

“…Additionally, DRT patients with a longer clinical course, higher CMT and central retinal vein occlusion (CRVO) tend to exhibit worse BCVA after treatment. …”
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Perspectives on Swedish Regulations for Online Record Access Among Adolescents With Serious Health Issues and Their Parents: Mixed Methods Study by Josefin Hagström, Charlotte Blease, Arja Harila, Päivi Lähteenmäki, Isabella Scandurra, Maria Hägglund

“…ConclusionsIn Sweden, ORA regulations and a lack of available information cause significant inconvenience for adolescents with serious health issues and their parents. …”
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Coexisting patterns and significance of serum HBV RNA and HBV DNA in patients with treatment-naïve chronic hepatitis B virus infection by Kun-yan Hao, Kun-yan Hao, Ye Fan, Yi-qing Zhang, Yue-cheng Yu

“…The HBV RNA (+) rates showed a significant difference (p &lt; 0.001) among the different HBsAg levels (10.00, 65.00, 84.21%, p &lt; 0.001), while the HBV DNA (+) rate showed no significant difference (p &gt; 0.05). …”
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