Staphylococcus aureus nt5 gene mutation through CRISPR RNA-guided base editing weakens bacterial virulence and immune evasion by Xinpeng Liu, Lan Huang, Yang Ye, Haiyi Wang, Min Tang, Fuqiang He, Zijing Xia, Shi Deng, Peng Zhang, Ruiwu Dai, Shufang Liang

“…In summary, nt5 gene mutation confers tolerance to DAP and a lower bacterial capacity to form kidney abscesses through phagocytosis of host immune cells, which indicates the targeted inhibition of NT5 protein would offer a potential new therapeutic strategy against S. aureus infection.…”
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Insulin Sensitivity and Beta-Cell Function Are Associated with Arterial Stiffness in Individuals without Hypertension by Chuchen Meng, Min Sun, Zhixiao Wang, Qi Fu, Mengdie Cao, Zhenxin Zhu, Jia Mao, Yun Shi, Wei Tang, Xiaoping Huang, Yu Duan, Tao Yang

“…We recruited 3137 nondiabetic individuals whose age, body mass index (BMI), glucose levels, blood pressure (BP), lipids, hemoglobin A1C (HbA1c), baPWV, and insulin levels were measured. …”
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Implementasi Algoritme Morus V2 untuk Pengamanan Data Pada Perangkat Bluetooth Low Energy by Diah Ratih Destyorini, Ari Kusyanti, Reza Andria Siregar

“…Data transmission will be insecure without a data security process. Cryptography is one of the options for securing data.  …”
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Case report: PD-L1-targeted high-affinity natural killer cells and IL-15 superagonist N-803-based therapy extend overall survival of advanced metastatic pancreatic cancer patients by Tara Seery, Lennie Sender, Omid Jafari, Frank Jones, Patricia Spilman, Sandeep B. Reddy, Patrick Soon-Shiong

“…BackgroundMetastatic pancreatic cancer (mPC) is an aggressive form of cancer with a poor prognosis and few therapeutic options after failure of the second-line treatment. …”
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پهنه‌بندی حساسیت خطر سیل در حوضه آبخیز رودخانه کشکان با استفاده از دو مدل WOE و EBF by فهیمه آزادی, سید حسن صدوق, منیژه قهرودی, هیمن شهابی

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Comparative Results of “Epi-Off” Conventional versus “Epi-Off” Accelerated Cross-Linking Procedure at 5-year Follow-Up by Cristina Ariadna Nicula, Dorin Nicula, Anca Maria Rednik, Adriana Elena Bulboacă

“…In both groups, Ksteep presented a similar decrease at 1 year (p=0.709), at 2 years (p=0.455), at 3 years (p=0.43), at 4 years (p=0.57), and at 5 years (p=0.494), with no statistically significant difference. …”
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Characteristics of Soil Active Carbon Fractions and Carbon Pool Stability in Major Forest Types in Northern Daxing’an Mountains by LIU Beibei, CAI Tijiu

“…Studying the pattern of change of soil active carbon fractions and carbon pool stability in different forest types is of great significance to the understanding of the biogeochemical processes of the carbon cycle, and can provide a basis for the management of ecosystem carbon pools oriented to carbon sequestration and emission reduction. …”
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Canine distemper outbreak and laryngeal paralysis in captive tigers (Panthera tigris) by Sarin Suwanpakdee, Anuwat Wiratsudakul, Nattarun Chaisilp, Luxsana Prasittichai, Anurux Skulpong, Patarapol Maneeorn, Benjaporn Bhusri, Chalisa Mongkolpan, Ruangrat Buddhirongawatr, Jarupa Taowan, Peerawat Wongluechai, Nlin Arya, Parin Suwannaprapha, Natharin Ngamwongsatit, Witthawat Wiriyarat, Nareerat Sangkachai

“…This study aimed to understand better the burden of CDV outbreaks in captive tiger populations in Thailand and a novel discovery of their clinical signs with a history of CDV exposure. …”
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Influence of catheter ablation for atrial fibrillation on atrial and ventricular functional mitral regurgitation by Masaharu Masuda, Kimiko Sekiya, Mitsutoshi Asai, Osamu Iida, Shin Okamoto, Takayuki Ishihara, Kiyonori Nanto, Takashi Kanda, Takuya Tsujimura, Yasuhiro Matsuda, Yosuke Hata, Hiroyuki Uematsu, Taku Toyoshima, Naoko Higashino, Toshiaki Mano

“…Patients with VFMR improvement showed a greater increase in LV ejection fraction than those without (amount of change: 28.5 ± 13.6% vs. 9.0 ± 14.8%, P = 0.001). …”
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Low-Dose Decitabine Assists Human Umbilical Cord-Derived Mesenchymal Stem Cells in Protecting β Cells via the Modulation of the Macrophage Phenotype in Type 2 Diabetic Mice by Jing Xue, Yu Cheng, Haojie Hao, Jieqing Gao, Yaqi Yin, Songyan Yu, Junyan Zou, Jiejie Liu, Qi Zhang, Yiming Mu

“…Progressive β-cell dysfunction, a major characteristic of type 2 diabetes (T2D), is closely related to the infiltration of inflammatory macrophages within islets. …”
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Functional and structural connectivity of the subregions of the amygdala in ADHD children with or without ODD by Zhao-Min Wu, Peng Wang, Xue-Chun Liu, Qing-Chao Zhou, Xiao-Lan Cao, Li Sun, Lu Liu, Qing-Jiu Cao, Li Yang, Yu-Feng Wang, Ying Qian, Bin-Rang Yang

“…Analysis of covariance (ANCOVA) was performed to test group-wise differences in these behavioral measures. A subsample comprising 209 participants underwent a resting-state functional MRI scan and a diffusion-weighted imaging (DWI) scan. …”
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Comparison of Individualized Rescue Luteal Phase Support Strategies with Vaginal and Combined Vaginal & Subcutaneous Progesterone Administration in Artificial Frozen-Thawed Blastoc... by Secil Irem Arik Alpcetin, Onur Ince, Bengisu Akcay, Munire Funda Cevher Akdulum, Erhan Demirdag, Ahmet Erdem, Ahmet Erdem, Mehmet Erdem, Mehmet Erdem

“…Regression analysis with a mixed model revealed that age, endometrial thickness, and estradiol levels were confounding factors as well as independent predictors of ongoing pregnancy rates (p<0.05). …”
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The Impact of Hyperoxia on Outcome of Patients Treated with Noninvasive Respiratory Support by Seyhan Pala Cifci, Yasemin Urcan Tapan, Bengu Turemis Erkul, Yusuf Savran, Bilgin Comert

“…Therefore, iatrogenic hyperoxia is a very common situation. The results from the recent clinical researches about hyperoxia indicate that hyperoxia can be related to worse outcomes than expected in some critically ill patients. …”
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The microbial communities and metabolic profiles of follicular fluid in patients with premature ovarian insufficiency by Wei Wang, Wei Wang, Mingming Shu, Jianhua Li, Qihang Wang, Wendan Zhang, Ye Wang, Yiming Guo, Yanbin Cheng, Honghong Jiang, Chunlan Song, Yuan Liu, Wei Shang, Wei Shang

“…IntroductionPremature ovarian insufficiency (POI) is a condition characterized by ovarian dysfunction occurring before the age of 40, and its etiology is multifactorial, including genetic, immunological, infectious, environmental, and iatrogenic factors, with over half of the cases remaining unexplained. …”
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Identification of core genes related to exosomes and screening of potential targets in periodontitis using transcriptome profiling at the single-cell level by Wufanbieke Baheti, Diwen Dong, Congcong Li, Xiaotao Chen

“…To pinpoint key cell types influencing the progression of periodontal at the single-cell level, a series of single-cell analyses covering pseudo-time series analysis were accomplished. …”
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Comparative Analysis of Meat Quality and Hindgut Microbiota of Cultured and Wild Bighead Carp (<i>Hypophthalmichthys nobilis</i>, Richardson 1845) from the Yangtze River Area by Abdullateef Mukhtar Muhammad, Chang Yang, Bo Liu, Cunxin Sun, Linghong Miao, Xiaochuan Zheng, Liangkun Pan, Dong Xia, Qun-Lan Zhou

“…Regarding the relationship between the hindgut microbiota and meat quality, <i>Mycobacterium</i> exhibited a positive correlation with the muscle n-6 PUFA content and a negative correlation with muscle n − 3 PUFAs, while <i>Clostridium_T</i> exhibited the opposite pattern. …”
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Nursing of four patients with acute pancreatitis after lower extremity endovascular intervention (4例下肢血管腔内治疗术后并发急性胰腺炎的护理体会) by FANG Xiaomei (方晓梅), LIU Huanping (刘焕萍), WANG Ting (王婷)

“…This paper summarized the nursing measures for four patients with acute pancreatitis after lower extremity endovascular intervention, and provided a reference for the postoperative nursing of vascular intervention surgery. …”
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Biological Behavior of Bioactive Glasses SinGlass (45S5) and SinGlass High (F18) in the Repair of Critical Bone Defects by Dayane Maria Braz Nogueira, Marcelie Priscila de Oliveira Rosso, Paulo Sérgio da Silva Santos, Manoel Damião Sousa-Neto, Alice Corrêa Silva-Sousa, Cleverson Teixeira Soares, Carlos Henrique Bertoni Reis, Jéssica de Oliveira Rossi, Cleuber Rodrigo de Souza Bueno, Daniela Vieira Buchaim, Rogério Leone Buchaim, Mariana Schutzer Ragghianti Zangrando

“…SinGlass High (F18) appears to be a viable alternative to autografts in bone repair, with potential to improve tissue integration and accelerate recovery.…”
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Förändringsrummet i fyra dimensioner: Att navigera osäkerhet och möjliggöra transformativt samskapande by Pia Andersson, Henrietta Palmer

“…This article is a contribution to the transdisciplinary research literature as well as to the practice and theory of interdisciplinary collaboration.  …”
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Removal of Matrix Interferences by Nano-MgO and Co-Adsorbents for Accurate Multi-Pesticide Residue Analysis in the Chinese Medicinal Herb, Paeoniae Radix Alba by Chunyu Wang, Xinquan Wang, Jiao Wang, Shanshan Di, Zhiwei Wang, Hao Xu, Huiyu Zhao, Changshan Zhao, Peipei Qi

“…A simple, accurate, and high-throughput analytical method was developed to detect 123 pesticide residues in Chinese medicinal herb Paeoniae Radix Alba (PRA) by introducing nano-MgO as a highly efficient purification material based on quick, easy, cheap, effective, rugged, and safe (QuEChERS) design concept. …”
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