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In Vitro Antiplasmodial, Cytotoxicity, and Antioxidant Activities of Lophira lanceolata (Ochnaceae): A Cameroonian Plant Commonly Used to Treat Malaria
Published 2023-01-01“…It tested in vitro the extracts against Plasmodium falciparum 3D7 and multiresistance Dd2. Macrophage cell lines (RAW 264.7 cells) and red blood cells were used for cytotoxicity tests. …”
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Identifying Primary Spontaneous Pneumothorax from Administrative Databases: A Validation Study
Published 2016-01-01Get full text
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THE ROLE OF ANTI-VEGF THERAPY IN IMPROVING THE EFFICACY OF SURGICAL TREATMENT OF SECONDARY NEOVASCULAR GLAUCOMA
Published 2024-10-01“…Patients underwent trabeculectomy (TE) according to our modification in 18 cases or implantation of the Ex-PRESS mini-shunt in 7 cases. Lucentis was injected intravitreally at a dose of 0.5 mg 5-7 days before surgery. …”
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Chemical Composition of Royal Jelly and Effects of Synbiotic with Two Different Locally Isolated Probiotic Strains on Antioxidant Activities
Published 2014-09-01“…IC50 values were estimated at 226.7 μg/mL for B. bifidum supplemented with 7.5% royal jelly and at 210.2 μg/ml for L. acidophilus supplemented with 2.5% royal jelly. …”
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Impact of Early versus Late Referral to Nephrologists on Outcomes of Chronic Kidney Disease Patients in Northern India
Published 2022-01-01“…A total of 91 (9.2%) patients died, 17 (1.7% ER and 74 (7.5%) patients in the LR group patients. …”
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A Systematic Review and Meta-Analysis of Outcomes for Type 1 Diabetes after Bariatric Surgery
Published 2016-01-01“…An improvement in HbA1c was also seen from 8.46±0.78% preoperatively to 7.95±0.55% (P=0.01) and 8.13±0.86% (P=0.03) at 12 months and at study endpoint, respectively. …”
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Ellagic Acid Alleviates Rheumatoid Arthritis in Rats through Inhibiting MTA1/HDAC1-Mediated Nur77 Deacetylation
Published 2021-01-01“…EA downregulated the MTA1/HDAC1 complex in MH7A cells. MTA1 knockdown inhibited proliferation, inflammation, and oxidative stress and promoted apoptosis in MH7A cells, while HDAC1 overexpression reversed these effects. …”
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Hepatocellular Carcinoma with Both Fibrolamellar and Classical Components: An Unusual Morphological Pattern
Published 2015-01-01Get full text
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XCL1-secreting CEA CAR-T cells enhance endogenous CD8+ T cell responses to tumor neoantigens to confer a long-term antitumor immunity
Published 2025-01-01“…We modified CEA-specific CAR-T cells, aiming to stimulate endogenous CD8+ T cell responses against neoantigens that were derived from CEA-positive tumors destroyed by the CAR T cells.Methods In a conventional CEA CAR (reg-CAR), we modified it to express lymphotactin XCL1 and interleukin (IL)-7 genes, constructing a modified 7XCL1-CAR. By generating the CEA-specific 7XCL1-CAR T cells, we assessed their antitumor efficacy against CRC cells with varying levels of CEA expression, both in cell-cultures and in two strains of tumor-bearing syngeneic mice.Results Following retroviral transduction, 7XCL1-CAR T cells and reg-CAR T cells exhibited similar positive proportions of CEA-CAR and CD4:CD8 ratios. …”
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Evaluation of treadmill cardiopulmonary exercise testing and field measurement results in women’s youth and adult national team water polo players
Published 2025-01-01“…No significant differences were found between CPET and swimming tests for resting heart rate (75[IQR:65–85] vs. 71[IQR:63–81] BPM, p = 0.33) and lactate levels (1.5[IQR:1.1–1.7] vs. 1.5[IQR:1.3–1.7] mM, p = 0.33). Maximal heart rates were higher during CPET than swimming (196.3 ± 9.7vs.191.0 ± 12.5 BPM, p < 0.001), while maximal lactate levels were lower (8.4 ± 2.4vs.9.6 ± 2.7 mM, p < 0.05).Lactate levels remained elevated after routine cool-down swimming ordered by the trainers, but decreased after suggested further training (6.6 ± 2.7vs.3.7 ± 1.6 mM, p < 0.001). …”
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تنقيب البيانات فى مجال المکتبات والمعلومات : مراجعة علمية
Published 2020-10-01Get full text
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