Synthesis and Microbiological Activity of Some Newly Synthesized Derivatives of 2-Oxo-2H-chromen-2-one by Majlinda Daci-Ajvazi, Sevdije Govori, Shuhreta Omeragiq

“…By the action of 2-amino-5-methylthio-1,3,4-thiadiazole, 3-amino-5-methylisoxazole, 2-amino-6-fluorobenzothiazole, 2-amino-5-chloropyridine, respectively, on 4-chloro-2-oxo-2H-chromene-3-sulfonyl chloride, the corresponding 9-methylthio-7,7-dioxo-7,7a-dihydro-5-oxo-7λ6,10-dithia-8,11-diaza-cyclopenta[b] phenantren-6-one, 9-methyl-7,7-dioxo-7H-5,8-dioxa-7λ6-thia-7a,11-diaza-cyclopenta[b] phenantren-6-one, 9-fluoro-7,7-dioxo-7H-5-oxa-7λ6,12-dithia-7a,13-diaza-indeno[1,2-b] phenantren-6-one and 9-Chloro-7,7-dioxo-7H-5-oxa-7λ6-thia-7a,12-diaza-benzo[α]anthracen -6-one were formed and they have been isolated in satisfying yields. …”
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Comparison of different GnRH compounds on fertility outcomes in ovulation synchronized and presynchronized beef cows by Nicola Oosthuizen, Lucas M. Goncalves, Samir Burato, Molly S. Smith, Kelsey M. Harvey, Graham Cliff Lamb, Graham Cliff Lamb, Pedro L. P. Fontes

“…Within each location, cows were randomly assigned to one of four treatments: (1 and 2) cows were estrus synchronized using the 7-day CO-Synch + CIDR protocol (7D) wherein they received an injection of one of two GnRH compounds [gonadorelin hydrochloride (GH) or gonadorelin diacetate tetrahydrate (GDT)] and a controlled internal drug release (CIDR) device on day 0, an injection of prostaglandin F2α (PG) at CIDR removal on day 7, and a second injection of their respective GnRH compound at fixed-time artificial insemination (TAI) on day 10 (7D-GH and 7D-GHT); (3 and 4) cows were treated with the 7&7 Synch (7&7) protocol, wherein they were treated the same as treatments 1 and 2 but received their CIDR inserts on day -7 in conjunction with an injection of PG (7&7-GH and 7&7-GDT). …”
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Investigating the reassortment potential and pathogenicity of the S segment in Akabane virus using a reverse genetics system by Eun-Jee Na, Chang-Gi Jeong, Su-Beom Chae, Jae-Ku Oem

“…Results The rAKAV-7ΔNSs virus, with a deletion in the NSs protein of the wild-type AKAV-7 virus (wtAKAV-7), and the rAKAV-7(S-K0505) virus, where the S segment of wtAKAV-7 was reassorted with that from the wild type K0505 strain (wtK0505), were successfully rescued. …”
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Targeted Antibiotic Prophylaxis for Lung Transplantation in Cystic Fibrosis Patients Colonised with Pseudomonas aeruginosa Using Multiple Combination Bactericidal Testing by Helmy Haja Mydin, Paul A. Corris, Audrey Nicholson, John D. Perry, Gerard Meachery, Emma C. L. Marrs, Steven Peart, Christine Fagan, James L. Lordan, Andrew J. Fisher, Frances K. Gould

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Truths and Lies from the Polysomnography ECG Recording: An Electrophysiologist Perspective by Adrian Baranchuk, Christina Quinlan, Kevin Michael, Christopher S. Simpson, Damian P. Redfearn, Michael Fitzpatrick

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Therapeutic Efficacy of Intranasal <i>N</i>-Acetyl-L-Cysteine with Cell-Penetrating Peptide-Modified Polymer Micelles on Neuropathic Pain in Partial Sciatic Nerve Ligation Mice by Hiroshi Nango, Ai Takahashi, Naoto Suzuki, Takumi Kurano, Saia Sakamoto, Taiki Nagatomo, Toyofumi Suzuki, Takanori Kanazawa, Yasuhiro Kosuge, Hiroko Miyagishi

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No effects of ozonated autohemotherapy on inflammation response in hemodialyzed patients by Leszek Tylicki, Bogdan Biedunkiewicz, Dominik Rachon, Tomasz Nieweglowski, Lukasz Hak, Andrzej Chamienia, Alicja Debska-Slizien, Ewa Aleksandrowicz, Jolanta Mysliwska, Boleslaw Rutkowski

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刘晓平 　区庆嘉 　黄洪莲　王小宁

“…目的: 研究小鼠 B7 基因转染对小鼠肝癌细胞 Hepal-6 细胞株细胞形态、生长速度及致瘤性的影响。方法: 用逆转录病毒载体,将 小鼠B7 基因导入小鼠肝癌细胞 Hepal-6 细胞株中,经G418 筛选,获得高表达 B7分子的阳性细胞克隆,采用CTLA-4Ig 的间接免疫荧光法检测 B7 分子的表达情况,并观察了B7 基因转染对细胞形态、生长速度及致瘤性的影响。…”
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Intrascrotal Dedifferentiated Leiomyosarcoma Originating from Dartos Muscle by Taro Teshima, Sayuri Takahashi, Shoichi Nagamoto, Hideyo Miyazaki, Tohru Nakagawa, Tetsuya Fujimura, Hiroshi Fukuhara, Haruki Kume, Yukio Homma

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Ahmed Glaucoma Valve Implantation in Vitrectomized Eyes by Nimet Yeşim Erçalık, Serhat İmamoğlu

“…Postoperative complications were bleb encapsulation (69.2%), early hypotony (38.5%), hyphema (23.1%), decompression retinopathy (23.1%), choroidal detachment (15.4%), intraocular hemorrhage (7.7%), and late endophthalmitis (7.7%). One eye (7.7%) was enucleated because of late endophthalmitis. …”
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The Inflammatory Response to Ruptured Abdominal Aortic Aneurysm Is Altered by Endovascular Repair by R. R. Makar, S. A. Badger, M. E. O'Donnell, C. V. Soong, L. L. Lau, I. S. Young, R. J. Hannon, B. Lee

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Probabilistic Short‐Term Solar Driver Forecasting With Neural Network Ensembles by Joshua D. Daniell, Piyush M. Mehta

“…A set of proxies and indices (drivers), F10.7, S10.7, M10.7, and Y10.7 are used as inputs by the JB2008, (https://doi.org/10.2514/6.2008‐6438) thermosphere density model. …”
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Early and Midterm Outcome of Surgical Repair of Total Anomalous Pulmonary Venous Connection by Sandy Adel, Karam Mosallam Eisa, Mohamed Adel Elgamal, Asmaa Gaber Rizk

“…Postoperative complications were pneumothorax in 2 (7.41%) patients, pulmonary edema in 1 (3.7%) patient, re-intubation in 2 (7.41%) patients, pneumonia in 1 (3.7%) patient, fits in 2 (7.41%) patients, thrombocytopenia in 1 (3.7%) patient, bleeding from ETT in 1 (3.7%) patient, LCOP in 5 (18.52%) patients, pulmonary hypertensive crisis in 3 (11.11%) patients, cardiac arrest in 1 (3.7%) patient, renal failure in 1 (3.7%) patient and no complication in 14 (51.85%) patients. …”
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Efficient Scheme for Implementing Large Size Signed Multipliers Using Multigranular Embedded DSP Blocks in FPGAs by Shuli Gao, Dhamin Al-Khalili, Noureddine Chabini

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A Scoping Review of Educational and Training Interventions on Parkinson’s Disease for Staff in Care Home Settings by Stacey Finlay, Tara Anderson, Elizabeth Henderson, Christine Brown Wilson, Patrick Stark, Gillian Carter, Matthew Rodger, Mihalis Doumas, Emma O’Shea, Laura Creighton, Stephanie Craig, Sophie Crooks, Arnelle Gillis, Gary Mitchell

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Target-specific peptides for BK virus agnoprotein identified through phage display screening: advancing antiviral therapeutics by Xiaofei Xing, Jingxian Han, Keke Wang, Fuyun Tian, CuiXia Jiang, Wei Liang, Lin Qi, Xin Yue, Yinhang Wen, Yuwei Hu, Hui Qiao

“…Subsequent analysis identified one 7-peptide and six 12-peptides within the binding peptides. …”
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The usefulness of presepsin in the early detection of anastomotic leakage after esophagectomy by Yoshiro Imai, Ryo Tanaka, Kentaro Matsuo, Hidero Yoshimoto, Mitsuhiro Asakuma, Hideki Tomiyama, Sang-Woong Lee

“…The area under the curve values for presepsin were highest on PODs 5 and 7 (0.89 and 0.83). Optimal cut-off values for presepsin were 400 pg/mL (sensitivity 100 %; specificity 81.9 %) on POD 5 and similar on POD 7. …”
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Helicobacter pylori Infection Elicits Type I Interferon Response in Human Monocytes via Toll-Like Receptor 8 Signaling by Chalystha Yie Qin Lee, Yee Teng Chan, Yi Ying Cheok, Grace Min Yi Tan, Ting Fang Tang, Heng Choon Cheong, Jamuna Vadivelu, Suhailah Abdullah, Chung Yeng Looi, Won Fen Wong

“…H. pylori infection-mediated IFN-α and IFN-β transactivation was significantly abrogated by the TLR7/8 (but not TLR7) antagonist. Additionally, TLR7/8 antagonist treatment reduced H. pylori infection-mediated phosphorylation of interferon regulatory factor 7 (IRF7). …”
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Development of Automatic Visceral Fat Volume Calculation Software for CT Volume Data by Mitsutaka Nemoto, Tusufuhan Yeernuer, Yoshitaka Masutani, Yukihiro Nomura, Shouhei Hanaoka, Soichiro Miki, Takeharu Yoshikawa, Naoto Hayashi, Kuni Ohtomo

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