Downregulation of LncRNA SNHG7 Sensitizes Colorectal Cancer Cells to Resist Anlotinib by Regulating miR-181a-5p/GATA6 by Deng Pan, Kehe Chen, Ping Chen, Yu Liu, Yingying Wu, Jingning Huang

“…It has been reported that small nucleolar RNA hostgene 7 (SNHG7) can sponge microRNAs to regulate colorectal cancer (CRC) progression. …”
Get full text

Suppression of Proinflammatory Cytokines and Mediators in LPS-Induced RAW 264.7 Macrophages by Stem Extract of Alternanthera sessilis via the Inhibition of the NF-κB Pathway by Katyakyini Muniandy, Sivapragasam Gothai, Khaleel M. H. Badran, S. Suresh Kumar, Norhaizan Mohd Esa, Palanisamy Arulselvan

“…In line with that, in this present study, we attempted to study the suppression activity of the proinflammatory cytokines and mediators as a characteristic of anti-inflammatory action, by using stem extract of A. sessilis in the lipopolysaccharide- (LPS-) stimulated RAW 264.7 macrophage cell line. The results showed that the extract has significantly inhibited the production of the proinflammatory mediators including NO and PGE2; cytokines comprising IL-6, IL-1β, and TNFα; and enzymes covering the iNOS and COX-2 by preventing the IκBα from being degraded, to inhibit the nuclear translocation of NF-κB subunit p65 in order to hinder the inflammatory pathway activation. …”
Get full text

Immunomodulatory Effect of Flavonoids of Blueberry (Vaccinium corymbosum L.) Leaves via the NF-κB Signal Pathway in LPS-Stimulated RAW 264.7 Cells by Dazhi Shi, Mengyi Xu, Mengyue Ren, Enshan Pan, Chaohua Luo, Wei Zhang, Qingfa Tang

“…FBL showed a significant reduction in the production of TNF-α in LPS-stimulated RAW 264.7 cells. FBL significantly decreased the expression of NF-κB p65 and P-NF-κB p65 in LPS-induced RAW 264.7 cells in a dose-dependent manner. …”
Get full text

Cloud-Based License Plate Recognition: A Comparative Approach Using You Only Look Once Versions 5, 7, 8, and 9 Object Detection by Christine Bukola Asaju, Pius Adewale Owolawi, Chuling Tu, Etienne Van Wyk

“…Using live video, we performed experiments on YOLOv5, YOLOv7, YOLOv8, and YOLOv9 models to detect number plates in real time. …”
Get full text

Gastric cancer-derived exosomal let-7 g-5p mediated by SERPINE1 promotes macrophage M2 polarization and gastric cancer progression by Zhenzhen Ye, Jianfeng Yi, Xiangyan Jiang, Wengui Shi, Hao Xu, Hongtai Cao, Long Qin, Lixin Liu, Tianming Wang, Zhijian Ma, Zuoyi Jiao

Subjects: Get full text

Role of gp91phox Homolog Nox1 in Induction of Premalignant Spindle Phenotypes of HPV 16 E6/E7—Immortalized Human Keratinocytes by Walee Chamulitrat

Get full text

Electroacupuncture attenuates ferroptosis by promoting Nrf2 nuclear translocation and activating Nrf2/SLC7A11/GPX4 pathway in ischemic stroke by Xi-chen Yang, Ya-ju Jin, Rong Ning, Qiu-yue Mao, Peng-yue Zhang, Li Zhou, Cheng-cai Zhang, Yi-chen Peng, Na Chen

“…The immunofluorescence and Western blotting were used to detect the expression of Total Nrf2, p-Nrf2, Nuclear Nrf2, and Cytoplasmic Nrf2, and the essential ferroptosis proteins, including glutathione peroxidase 4 (GPX4), solute carrier family 7 member 11 (SLC7A11) and ferritin heavy chain 1 (FTH1). …”
Get full text

Real world efficacy and safety of the advanced hybrid closed-loop system MiniMed 780G (SmartGuard) in children under 7 years of age by Sara López-López, Cristina Díaz-Martín, Inés García-de Pablo, María Teresa Ovejero-Garcia, María Beatriz Garnier-Rodríguez, Ruth Molina-Suárez, Cristina Ontoria-Betancort, Blanca Sáez-Gallego, Ángela Domínguez-García, Sofía Quinteiro-González, Lourdes Travieso-Suárez, María Fátima Cabrera-Guedes, Yeray Nóvoa-Medina, Yeray Nóvoa-Medina, Yeray Nóvoa-Medina

“…ObjectiveTo evaluate the safety and efficacy of the Medtronic 780G SmartGuard™ AID system in children under 7 years of age with type 1 diabetes (T1D).MethodsRetrospective analysis of data from children living with T1D under 7 years of age using the MiniMed 780G™ across three pediatric endocrinology units in the Canary Islands. …”
Get full text

TECHNIQUE AND TECHNOLOGY OF PRODUCTION OF TWO-LAYER ROLLED WIRE SPIRAL CONSTRUCTIONS 2+7 AND 3+9 WITH DIFFERENT STEPS OF DISCHARGING BY LAYS IN ONE TECHNOLOGICAL OPERATION by Ju. L. Hudolej

Get full text

Anisodamine ameliorates crystalline silica-exposed pulmonary inflammation and fibrosis via the α7nAChR/JAK2/STAT3 signaling pathway by Meng Liu, Hui Liu, Hong Kang, Juan Wu, Puhua Xing, Xiaorui Ding, Yangyang Wei, Xiaomei Kong

Subjects: Get full text

Temperature Dependence of the Tilt Angle for the Smectic A-Smectic Transition in a Mixture of C7-70PDOB Ferroelectric Liquid Crystals near the Tricritical Point by Mustafa Kurt, Hamit Yurtseven

“…Our results show that the mean-field theory explains adequately the observed behaviour of the C7-70PD0B mixture near the tricritical point.…”
Get full text

Nicorandil Ameliorates Depression‐Like Behaviors After Traumatic Brain Injury by Suppressing Ferroptosis Through the SLC7A11/GPX4 Axis in the Hippocampus by Yao‐Ran Tu, Ming Tan, Yao Li, De‐Quan Hong, Fan Niu

Subjects: Get full text

Human papillomavirus type 16 E7 promotes cell viability and migration in cervical cancer by regulating the miR-23a/HOXC8 axis by Yahang Chen, Lei Sun, Lin Li

Subjects: “…human papillomavirus type 16 E7…”
Get full text

Mechanism of Inflammation Regulation of α7nAChR in Spleen and Spinal Dorsal Horn of Mice with Paclitaxel-induced Neuropathic Pain by Electroacupuncture on Zusanli Acupoint by PANG Lina, LAN Yanyan, WANG Zhifu, CHEN Xiaomei, YU Xiangmei

Subjects: Get full text

The immune checkpoint molecule B7-H4 regulates β-cell mass and insulin secretion by modulating cholesterol metabolism through Stat5 signalling by Fangzhen Xia, Ziteng Zhang, Zhen Qian, Xiaoyu Fang, Junxue Wang, Yan Wang, Guoting Sun, Yuefeng Yu, Ninjian Wang, Junke Zhen, Yan Liu, Yingli Lu

Subjects: “…B7-H4…”
Get full text

Gardenoside attenuates Staphylococcus aureus-induced mastitis by inhibiting inflammation and ferroptosis through Nrf2/SLC7A11/GPX4 signaling pathway by Guoqing Sui, Wei Jiang, Lianyue Guan

“…Meanwhile, GSH level and GPX4, SLC7A11, and ferritin expressions were increased by GAD treatment. …”
Get full text

Targeting EGFR-binding protein SLC7A11 enhancing antitumor immunity of T cells via inducing MHC-I antigen presentation in nasopharyngeal carcinoma by Haihua Wang, Songqing Fan, Yuting Zhan, Yue Xu, Yao Du, Jiadi Luo, Hongjing Zang, Shuping Peng, Weiyuan Wang

“…We discovered that EGFR, operating in a kinase-independent manner, played a role in stabilizing the expression of SLC7A11, which subsequently inhibited MHC-I antigen presentation. …”
Get full text

7 Can we take a MEASURED (MRI-Enabled Active Surveillance Using Risk adaptEd decisions)approach to active surveillance for prostate cancer? by C. Moore, B. Adebusoye, D. Maffei, C. Englman, F. Giganti, S. Mallet

Get full text

Crystal structure of 3,5–di-O-benzoyl-1,2-O-isopropylidene-α–D-ribose, C22H22O7 by Wu Binbin, Chen Guangying, Ding Haixin

“…C22H22O7, orthorhombic, C2221 (no. 20), a = 8.891(2) Å, b = 17.938(5) Å, c = 25.996(6) Å, V = 4146.0(18) Å3, Z = 8, R gt(F) = 0.0461, wR ref(F 2) = 0.1189, T = 296 K.…”
Get full text

Modifications of the Glycosaminoglycan-Linkage Region of Proteoglycans: Phosphorylation and Sulfation Determine the Activity of the Human ß1,4-Galactosyltransferase 7 and ß1,3-Glucuronosyltransferase I by Sandrine Gulberti, Virginie Lattard, Magali Fondeur, Jean-Claude Jacquinet, Guillermo Mulliert, Patrick Netter, Jacques Magdalou, Mohamed Ouzzine, Sylvie Fournel-Gigleux

Get full text