LINC00941 affects the proliferation, apoptosis and differentiation of osteoblasts by regulating the miR-335-5p/KAT7 axis by Longjin Liu, Ye Yang, Pengxiao Sun

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Antileishmanial Effect of 5,3′-Hydroxy-7,4′-dimethoxyflavanone of Picramnia gracilis Tul. (Picramniaceae) Fruit: In Vitro and In Vivo Studies by Sara M. Robledo, Wilson Cardona, Karen Ligardo, Jéssica Henao, Natalia Arbeláez, Andrés Montoya, Fernando Alzate, Juan M. Pérez, Victor Arango, Iván D. Vélez, Jairo Sáez

“…The majoritarian metabolite was 5,3′-hydroxy-7,4′-dimethoxyflavanone ether that exhibited high activity against L. …”
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Evaluation of cytotoxic, antimicrobial, and antioxidant activi-ties of Echium italicum L. in MCF-7 and HepG2 cell lines by Dilek Arslan Atessahin, Semih Dalkilic, Lütfiye Kadioglu Dalkilic, Dudu Bayindir, Elif Cetinkaya

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Uptake of CCR7 by KIR2DS4+ NK Cells Is Induced upon Recognition of Certain HLA-C Alleles by Silvia Pesce, Simona Carlomagno, Alessandro Moretta, Simona Sivori, Emanuela Marcenaro

“…We demonstrate that KIR2DS4 can induce the uptake of CCR7 by KIR2DS4+ NKG2A+ NK cell clones after interacting with CCR7+ target cells expressing HLA-Cw4 and HLA-Cw6 alleles. …”
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FBXW7 Reduces the Cancer Stem Cell-Like Properties of Hepatocellular Carcinoma by Regulating the Ubiquitination and Degradation of ACTL6A by Xing Wang, Ying Li, Yongning Li, Peng Liu, Songbai Liu, Yaozhen Pan

“…We confirmed ACTL6A as a novel downstream target for FBXW7. The in vivo ubiquitination assay showed that FBXW7 repressed HCC malignancy by regulating the oncogenic activity of ACTL6A in a ubiquitin-dependent manner. …”
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Kinematic Rupture Process of Manyas (Mw=4.7) and Gemlik (Mw=4.8) Earthquakes Occurred in The Southern Marmara Region by Feyza Nur Bekler, Nurcan Meral Özel, Gülüm Tanırcan

“…Source characterization and slip history were estimated for two moderate-sized earthquakes which occurred on the southern branch of the North Anatolian Fault zone (NAFz): October 20, 2006 (Mw 4.7) Manyas Earthquake and October 24, 2006 (Mw 4.8) Gulf of Gemlik Earthquake. …”
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Discovery of Novel Nav1.7-Selective Inhibitors with the 1H-Indole-3-Propionamide Scaffold for Effective Pain Relief by Gaoang Wang, Hang Wu, Yingying Wang, Xiangying Liu, Shuijiao Peng, Wenxing Wang, Meijing Wu, Yifei Liu, Ercheng Wang, Zhe Wang, Lei Xu, Xiaojian Wang, Wei Yang, Haiyi Chen, Xi Zhou, Tingjun Hou

“…Nav1.7 is considered a promising target for developing next-generation analgesic drugs, given its critical role in human pain pathologies. …”
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Perfil do desenvolvimento dos escolares de 7 a 14 anos do município de Marechal Cândido Rondon by Herton Xavier Corseuil

“… Objetivo: O estudo objetivou analisar o perfil de crescimento físico e o estado nutricional de escolares de 7 a 14 anos do município de Marechal Cândido Rondon, Paraná. …”
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Effect of phosphorus and gallium on oxidation resistance of Sn-0.7Cu brazing metal: First-principle calculation and experimental verification by Lingyue Wang, He Wei, Chen Liu, Shiyu Yang, Zulai Li, Min Zha

“…In this paper, the mechanism of the effect of phosphorus and gallium on the oxidation resistance of Sn-0.7Cu brazing alloy was studied based on the calculation of first principles. …”
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Functional connectivity-based compensation in the brains of non-demented older adults and the influence of lifestyle: A longitudinal 7-year study by Pascal Frédéric Deschwanden, Isabel Hotz, Susan Mérillat, Lutz Jäncke

“…Methods: Using longitudinal data from 228 cognitively healthy older adults, we analyzed five measurement points over 7 years. Network-based statistics and latent growth modeling were employed to examine changes in structural and functional connectivity, as well as potential functional compensation for declines in processing speed and memory. …”
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Isolation and Physiomorphological Characterization of Escherichia coli O157:H7-Infecting Bacteriophages Recovered from Beef Cattle Operations by Pushpinder Kaur Litt, Divya Jaroni

“…Bacteriophages, recovered from beef cattle environment and specifically targeting Escherichia coli O157:H7, were examined for their physiological and morphological characteristics. …”
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Topographical mapping of metabolic abnormalities in multiple sclerosis using rapid echo-less 3D-MR spectroscopic imaging at 7T by Eva Niess, Assunta Dal-Bianco, Bernhard Strasser, Fabian Niess, Lukas Hingerl, Beata Bachrata, Stanislav Motyka, Paulus Rommer, Siegfried Trattnig, Wolfgang Bogner

“…Objectives: To assess topographical patterns of metabolic abnormalities in the cerebrum of multiple sclerosis (MS) patients and their relationship to clinical disability using rapid echo-less 3D-MR spectroscopic imaging (MRSI) at 7T. Materials and Methods: This study included 26 MS patients (13 women; median age 34) and 13 age- and sex-matched healthy controls (7 women; median age 33). …”
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CCR7 and CD48 as Predicted Targets in Acute Rejection Related to M1 Macrophage after Pediatric Kidney Transplantation by Jie Zhang, Jun Pei, Chengjun Yu, Jin Luo, Yifan Hong, Yi Hua, Guanghui Wei

“…Two Hub genes, namely CCR7 and CD48, were identified by PPI and Cytoscape analysis. …”
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A Case Report of Aicardi-Goutières Syndrome Type 7 Caused by IFIH1 Gene Mutation and a Literature Review by ZHAO Min, SHU Zhou, HAN Tongxin, FU Yanhua, GAO Tianji, MAO Huawei

“…ObjectiveTo explore the clinical and genetic features of Aicardi-Goutières syndrome (AGS) caused by IFIH1 gene mutation.MethodsWe analyzed the clinical features and genetic mutation results of a boy with AGS type 7 and conducted a retrospective review of the literature of the characteristics and clinical features of IFIH1 gene mutations in AGS type 7.ResultsIn the case of this report, the patient, 13-year-old boy, exhibited gait abnormalities at age 3. …”
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Meeting Report: International Magnetosphere Coupling IV (IMC‐IV) Workshop GFZ‐Potsdam, Germany, 2–7 June 2024 by Julia Himmelsbach, Yuri Y. Shprits

“…Abstract The International Magnetospheric Coupling (IMC‐IV) Workshop was held from 2–7 June 2024, at GFZ‐Potsdam, Germany and convened over 140 scientists to explore the solar wind and magnetosphere‐ionosphere‐thermosphere coupling. …”
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Expression of Toll-Like Receptors 3, 7, and 9 in Peripheral Blood Mononuclear Cells from Patients with Systemic Lupus Erythematosus by Agnieszka Klonowska-Szymczyk, Anna Wolska, Tadeusz Robak, Barbara Cebula-Obrzut, Piotr Smolewski, Ewa Robak

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Influenza A Virus H7 nanobody recognizes a conserved immunodominant epitope on hemagglutinin head and confers heterosubtypic protection by Zhao-Shan Chen, Hsiang-Chi Huang, Xiangkun Wang, Karin Schön, Yane Jia, Michael Lebens, Danica F. Besavilla, Janarthan R. Murti, Yanhong Ji, Aishe A. Sarshad, Guohua Deng, Qiyun Zhu, Davide Angeletti

“…Here, we isolate and purify a hemagglutinin (HA)-specific nanobody that recognizes an H7 subtype of influenza A virus. The nanobody, named E10, exhibits broad-spectrum binding, cross-group neutralization and in vivo protection across various influenza A subtypes. …”
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HBsAg及 B7-1 双表达重组逆转录病毒载体的构建 by 周　智, 姚集鲁, 杨　林, 邓练贤, 卢建溪

“…【目的】为探索共刺激分子 B7-1 增强 HBsAg 真核表达载体基因免疫的效果,并用于消除乙肝免疫耐受。【方法】 用高保真 PCR 法扩增目的基因片段 B7-1 及带接头和启动子的 IRES-HBs 基因片段,亚克隆到 pBluescript KS+载体中测序,再 克隆到逆转录病毒载体 PLXSN 中。…”
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CpG Oligodeoxynucleotides Inhibit RANKL-Induced Osteoclast Formation by Upregulating A20 Deubiquitinase in RAW 264.7 Cells by Seong-Kyu Kim, Jung-Yoon Choe, Ki-Yeun Park

“…This study showed that CpG-ODN suppressed RANKL-induced osteoclast formation through regulation of the A20-TRAF6 axis in RAW 264.7 cells.…”
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TSG-6 Downregulates IFN-Alpha and TNF-Alpha Expression by Suppressing IRF7 Phosphorylation in Human Plasmacytoid Dendritic Cells by L. Kui, G. C. Chan, P. P. W. Lee

“…By CD44 blocking assay, we deduced that the suppressive effect of TSG-6 is mediated by CD44, by reducing IRF-7 phosphorylation. Our findings suggest that TSG-6 and its downstream signalling pathway could potentially be targeted to modulate proinflammatory cytokine expression in pDCs.…”
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