Outcomes of Late-Onset Bleb-Related Endophthalmitis Treated with Pars Plana Vitrectomy by Kazuyoshi Ohtomo, Chihiro Mayama, Takashi Ueta, Miyuki Nagahara

“…Bleb leakages were observed in 7 eyes (64%). On culture examinations, highly pathogenic bacteria (HPB) were identified in 6 cases (55%). …”
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Genotypes, Antibiotic Resistance, and ST-8 Genetic Clone in Campylobacter Isolates from Sheep and Goats in Grenada by Diana M. Stone, Yogesh Chander, Aschalew Z. Bekele, Sagar M. Goyal, Harry Hariharan, Keshaw Tiwari, Alfred Chikweto, Ravindra Sharma

“…Fifteen Campylobacter isolates were obtained (14 C. jejuni and 1 C. coli). The prevalence (3.7%) did not differ significantly between sheep (4.5%) and goats (3.2%). …”
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From botany to bedside: a review of the health benefits of Lycium barbarum as a functional food by Alois Berisha, Elena-Alexandra Alexa, Robbie Kelleher, Tao Zhang

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Serum Vascular Endothelial Growth Factor Levels before and after Intravitreous Ranibizumab Injection for Retinopathy of Prematurity by Xuting Chen, Lin Zhou, Qi Zhang, Yu Xu, Peiquan Zhao, Hongping Xia

“…The serum concentrations of VEGF 1 day before and 1 day, 3 days, and 7 days after a total of 0.5 mg intravitreal injections of ranibizumab were 226.9 (198.4, 272.4), 12.8 (7.0, 22.4), 16 (12.0, 20.8), and 33.7 (24.0, 48.0) pg/ml, respectively. …”
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Alginate Hydrogel Beads with a Leakproof Gold Shell for Ultrasound-Triggered Release by Marcus Flowers, Alex Paulsen, Claire R. W. Kaiser, Adam B. Tuma, Hubert H. Lim, Brenda M. Ogle, Chun Wang

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Microradiography of Microcalcifications in Breast Specimen: A New Histological Correlation Procedure and the Effect of Improved Resolution on Diagnostic Validity by H.-J. Langen, S. Koehler, J. Bielmeier, R. Jocher, D. Kranzfelder, N. Jagusch, G. Treutlein, Th. Wetzler, J. Müller, G. Ott

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Generation of iPSCs by Nonintegrative RNA-Based Reprogramming Techniques: Benefits of Self-Replicating RNA versus Synthetic mRNA by Heidrun Steinle, Marbod Weber, Andreas Behring, Ulrike Mau-Holzmann, Christian Schlensak, Hans Peter Wendel, Meltem Avci-Adali

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Comparative efficacy of uterine artery embolization versus laparoscopic myomectomy in treating uterine fibroids: a propensity score matched analysis by Cunbao Wei, Xingwei Sun, Shenzhi Li, Xuming Bai, Yong Jin

“…However, UAE patients faced higher hospitalization costs (P < 0.001). Adverse event rates (7.6% vs. 9.1%) and postoperative reintervention rates (7.6% vs. 7.6%) were relatively low and not significantly different between groups (P > 0.05). …”
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Sphingosine-1-Phosphate Signaling in Immune Cells and Inflammation: Roles and Therapeutic Potential by Masayo Aoki, Hiroaki Aoki, Rajesh Ramanathan, Nitai C. Hait, Kazuaki Takabe

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3′ Splice Site Sequences of Spinal Muscular Atrophy Related SMN2 Pre-mRNA Include Enhancers for Nearby Exons by Sunghee Cho, Heegyum Moon, Tiing Jen Loh, Hyun Kyung Oh, Hey-Ran Kim, Myung-Geun Shin, D. Joshua Liao, Jianhua Zhou, Xuexiu Zheng, Haihong Shen

“…Although human patients contain SMN2, a duplicate of SMN1, splicing of SMN2 produces predominantly exon 7 skipped isoform. In order to understand the functions of splice site sequences on exon 7 and 8, we analyzed the effects of conserved splice site sequences on exon 7 skipping of SMN2 and SMN1 pre-mRNA. …”
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Brillouin–Mandelstam scattering in telecommunications optical fiber at millikelvin temperatures by E. A. Cryer-Jenkins, A. C. Leung, H. Rathee, A. K. C. Tan, K. D. Major, M. R. Vanner

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Aβ 不同片段肽疫苗免疫鼠后血清对 Aβ42诱导细胞毒性作用的影响

“…【目的】探讨Aβ42及其亚单位疫苗免疫鼠后其血清对Aβ42诱导的细胞毒性作用的影响,为其体内应用提供依据。【方法】①用间接ELISA法测定Aβ42和K7Aβ36-42疫苗接种鼠后的血清中抗体滴度;②将不同浓度的Aβ42和K7Aβ36-42加入培养有PC12细胞的96孔培养板中,检测其对PC12细胞的毒性作用;③用不同浓度的Aβ42及K7Aβ36-42疫苗免疫鼠血清加入含Aβ42的培养基中,与PC12一起孵育培养,7d后用MTT法和酶标仪测定存活细胞的A值。…”
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Rheumatoid factor isotypes in rheumatoid arthritis diagnosis and prognosis: a systematic review and meta-analysis by Nicola Bizzaro, Franco Franceschini, Maria Infantino, Carlo Selmi, Gian Domenico Sebastiani, Francesca Motta, Davide Giavarina, Boaz Palterer

“…Testing all RF isotypes with latex test or nephelometry allows for the highest sensitivity (68.6%, 95% CI 66.2% to 71.0%); nonetheless, the determination of IgA isotype provides the highest specificity (91.4%, 95% CI 90.8% to 92.0%) and the highest positive likelihood ratio (7.7, 95% CI 5.7 to 10.4). When testing IgM isotype the highest diagnostic OR (21.7, 95% CI 16.1 to 29.3) is reached. …”
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Clinical Characteristics and Outcome of Kidney Transplant Recipients Infected with COVID-19: A Retrospective Observational Study by Manzoor Ahmad Parry, Rayees Yousuf Sheikh, Raja Kaamil Qadri, Muzafar Maqsood Wani, Imtiyaz Wani, Mohammad Ashraf Bhat

“…Results: The mean age in patients with mild COVID-19 disease was 37.1 ± 9.1 years, whereas those with moderate and severe disease were 44.7 ± 13.7 and 48.1 ± 11.2 years, respectively (P = 0.02). …”
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Prognostic Utility of Prechemoradiotherapy Albumin-to-Alkaline Phosphatase Ratio in Unresectable Locally Advanced Pancreatic Carcinoma Patients by Veysel Haksoyler, Erkan Topkan

“…At a median follow-up of 14.8 months (range: 3.2-85.7), the median PFS and OS times were 7.5 (95% confidence interval (CI): 6.0-9.0) and 14.9 months (95% CI: 11.9-17.9), respectively. …”
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Cytotoxic Phenolic Compounds from Fruit Glandular Trichomes of Macaranga tanarius by Thi Mai Huong Doan, Thuy Linh Nguyen, Thi Thanh Van Trinh, Van Nam Vu, Thi Dao Phi, Marc Litaudon, Fanny Roussi, Van Minh Chau, Van Cuong Pham

“…Compounds 1 and 6 showed weak cytotoxic activities against KB cell line with IC50 values of 29.3 and 24.7 μM, respectively.…”
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Submucosal Tunnel Endoscopic Resection for Esophageal Submucosal Tumors: A Multicenter Study by Sufang Tu, Silin Huang, Guohua Li, Xiaowei Tang, Haitao Qing, Qiaoping Gao, Jingwen Fu, Guoping Du, Wei Gong

“…Regarding complications, there were 9 (7.8%) cases of perforation, 2 (1.7%) cases of pneumothorax, and 9 (7.8%) cases of subcutaneous emphysema. …”
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Altered Viral Replication and Cell Responses by Inserting MicroRNA Recognition Element into PB1 in Pandemic Influenza A Virus (H1N1) 2009 by Xiaoyue Shen, Wenkui Sun, Yi Shi, Zheng Xing, Xin Su

“…We inserted an MRE of microRNA-let-7b (miR-let-7b) into the open reading frame of PB1 to test the feasibility of creating a cell-restricted H1N1pdm virus since let-7b is abundant in human bronchial epithelial cells. …”
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Effectiveness of Ascophyllum nodosum and Fucus vesiculosus on Metabolic Syndrome Components: A Real-World, Observational Study by Antonio Nicolucci, Maria Chiara Rossi, Massimiliano Petrelli

“…After 6 months of treatment with Gdue, body weight was reduced on average by 7.3 kg (-8.0; -6.6), waist circumference by 7.5 cm (-8.2; -6.8), fasting blood glucose by 16.3 mg/dL (-17.8; -14.7), HbA1c by 0.55% (-0.62; -0.49), systolic and diastolic blood pressure by 7.1 mmHg (-8.3; -6.0) and 4.2 mmHg (-5.0; -3.5), respectively, LDL cholesterol by 18.2 mg/dL (-21.2; -15.3), and triglycerides by 39 mg/dL (-45; -32). …”
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Perinatal consequences of a category 1 caesarean section at term by Sailesh Kumar, Leah Grace, Ristan M Greer

“…Significantly higher (p&lt;0.001) perinatal complications were seen in the category 1 CS cohort—Apgar scores &lt;7 at 1 min (20.4%, 241/1179 vs 10.7%, 377/3527) and 5 min (5.8%, 68/1179 vs 1.9%, 67/3527), umbilical arterial pH&lt;7.2 (23.7%, 279/1179 vs 9.1%, 321/3527), neonatal resuscitation (59.9%, 706/1179 vs 51.8%, 1828/3527), neonatal intensive care unit admission (9.8%, 116/1179 vs 2.5%, 87/3527) and seizures (0.8%, 10/1179 vs 0.3%, 9/3527), respectively.Conclusions These results demonstrate significantly poorer outcomes associated with term category 1 CS compared with non-category 1 emergency CS.…”
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