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  1. 3181

    Benchmarking COMSOL Multiphysics Single-Subchannel Thermal-Hydraulic Analysis of a TRIGA Reactor with RELAP5 Results and Experimental Data by Ahmed K. Alkaabi, Jeffrey C. King

    Published 2019-01-01
    “…The aim of this study is to benchmark the prediction accuracy of COMSOL Multiphysics in performing thermal-hydraulic analysis of TRIGA (Training, Research, Isotopes, General Atomics) reactors such as the Geological Survey TRIGA Reactor (GSTR) by comparing its predictions with RELAP5 (a widely used code in nuclear thermal-hydraulic analysis) results and experimental data. …”
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  3. 3183

    RNase P cleavage of pseudoknot substrates reveals differences in active site architecture that depend on residue N-1 in the 5’ leader by David M. Kosek, J. Luis Leal, Ema Kikovska-Stojanovska, Guanzhong Mao, Shiying Wu, Samuel C. Flores, Leif A. Kirsebom

    Published 2025-12-01
    “…We show that a small biotin-binding RNA aptamer that folds into a pseudoknot structure acts as a substrate for bacterial RNase P RNA (RPR) with and without the RNase P C5 protein. Cleavage in the single-stranded region in loop 1 was shown to depend on the presence of a RCCA-motif at the 3’ end of the substrate. …”
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  4. 3184

    Comparative evaluation of cell-based assay technologies for scoring drug-induced condensation of SARS-CoV-2 nucleocapsid protein by Rui Tong Quek, Cyna R. Shirazinejad, Christina L. Young, Kierra S. Hardy, Samuel Lim, Phillip J. Elms, David T. McSwiggen, Timothy J. Mitchison, Pamela A. Silver

    Published 2025-03-01
    “…We applied these methods to evaluate condensation of the SARS-CoV-2 nucleocapsid (N) protein under GSK3 inhibitor treatment, which we had previously identified in our HCS campaign to induce condensation with well-defined structure-activity relationships (SAR). …”
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