Challenges and strategies in the soluble expression of CTA1-(S14P5)4-DD and CTA1-(S21P2)4-DD fusion proteins as candidates for COVID-19 intranasal vaccines. by Simson Tarigan, Gita Sekarmila, Apas, Sumarningsih, Ronald Tarigan, Riyandini Putri, Damai Ria Setyawati

“…Inducing expression with IPTG at the early log phase significantly increased soluble CTA1-(S21P2)4-DD but not CTA1-(S14P5)4-DD. Adding non-denaturing detergents (Nonidet P40, Triton X100, or Tween 20) to the extraction buffer significantly enhanced solubility. …”
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Study of solid state interactions in the systems ZnFe2O4 - CaO, ZnFe2O4 - MgO and zinc cake with CaO and MgO by Peltekov A.B., Boyanov B.S.

Subjects: “…ZnFe2O4…”
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Synthesis and Anti-inflammatory Activity of Some Novel 3-(6-Substituted-1, 3-benzothiazole-2-yl)-2-[{(4-substituted phenyl) amino} methyl] quinazolines-4 (3H)-ones by Manish Srivastav, MD. Salahuddin, S. M. Shantakumar

“…A series of novel 3-(6-substituted-1, 3-benzothiazole-2-yl)-2-[{(4-substituted phenyl) amino} methyl] quinazolines-4(3H)-ones were synthesized by treating 2-(chloromethyl)-3-(6-substituted-1, 3-benzothiazole-2-yl) quinazoline-4-(3H)-one (IIa-d) with various substituted amine. …”
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Significant Depletion of CD4+ T Cells Occurs in the Oral Mucosa during Simian Immunodeficiency Virus Infection with the Infected CD4+ T Cell Reservoir Continuing to Persist in the Oral Mucosa during Antiretroviral Therapy by Jeffy George, Wendeline Wagner, Mark G. Lewis, Joseph J. Mattapallil

“…Repopulating CD4+ T cells harbored a large fraction of Th17 cells suggesting that ART potentially reconstitutes oral mucosal immunity. …”
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Crystal structure of 2-[(4-bromobenzyl)thio]-5-(5-bromothiophen-2-yl)-1,3,4-oxadiazole, C13H8Br2N2OS2 by Al-Omary Fatmah A. M., Blacque Olivier, Alanazi Fahdah S., Tiekink Edward R. T., El-Emam Ali A.

“…C13H8Br2N2OS2, monoclinic, Pc (no. 7), a = 13.4050(4) Å, b = 4.7716(1) Å, c = 11.7303(4) Å, β = 105.885(3)∘$105.885{(3)}^{\circ }$, V = 721.66(4) Å3, Z = 2, Rgt${R}_{gt}$(F) = 0.0294, wRref$w{R}_{ref}$(F2 = 0.0808, T = 160 K.…”
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Directed Flow of Λ, Λ3H and Λ4H in Au+Au collisions at √sNN = 3.2, 3.5, 3.9 and 4.5 GeV at RHIC by Han Junyi

“…In these proceedings, we present a systematic study on energy dependence of the directed flow (v1) for Λ and hyper-nuclei (3ΛH and 4ΛH) from mid-central Au+Au collisions at √sNN = 3.2, 3.5, 3.9 and 4.5 GeV, collected by the STAR experiment with the fixed-target mode during BES-II. …”
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Evaluation of Therapeutic Efficacy and Safety of Tranexamic Acid Local Infiltration in Combination with Topical 4% Hydroquinone Cream Compared to Topical 4% Hydroquinone Cream Alone in Patients with Melasma: A Split-Face Study by Zohreh Tehranchinia, Bita Saghi, Hoda Rahimi

“…Thus, we conducted this study to evaluate the efficacy and safety of tranexamic acid local infiltration in combination with topical 4% hydroquinone cream compared to topical 4% hydroquinone cream alone in patients with melasma. …”
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Crystal structure of 1-isopropyl-3-(prop-1-en-2-yl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine, C11H15N5 by Wang Yanjiao, Tang Xiaoqin, Liu Bin

“…C11H15N5, monoclinic, P21/c (no. 14), a = 9.5677(16) Å, b = 8.1755(15) Å, c = 14.846(3) Å, β = 93.783(4)°, V = 1158.7(4) Å3, Z = 4, Rgt(F) = 0.0473, wRref(F2) = 0.1425, T = 173 K.…”
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Design, synthesis, and anti-inflammatory activity of 2H-1,4-benzoxazin-3(4H)-one derivatives modified with 1,2,3-triazole in LPS-induced BV-2 cells by Xixi Hou, Xixi Hou, Longfei Mao, Huibin Zhang, Lan Wang, Baoyu He, Jingjing Guo, Jianji Wang

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The crystal structure of 4-(((3-bromo-5-(trifluoromethyl)pyridin-2-yl)oxy)methyl)benzonitrile, C28H16Br2F6N4O2 by Lu Zhi-Qiang

“…C28H16Br2F6N4O2, triclinic, P1‾$\overline{1}$ (no. 2), a = 8.0085(4) Å, b = 13.6578(7) Å, c = 14.1964(6) Å, α = 96.950(4)°, β = 105.376(4)°, γ = 106.772(5)°, V = 1400.32(12) Å3, Z = 2, Rgt(F) = 0.0570, wRref(F2) = 0.1268, T = 293(2) K.…”
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Remarkable Conversion of 2-Thioxo-2,3-dihydroquinazolin-4(1H)-ones into the Corresponding Quinazoline-2,4(1H,3H)-diones: Spectroscopic Analysis and X-Ray Crystallography by Adel S. El-Azab, Nasr Y. Khalil, Alaa A.-M. Abdel-Aziz

“…A simple and efficient new synthetic method to obtain 3-substituted quinazolin-2,4-diones 9–16 by the reaction of 3-substituted 2-thioxo-quinazolin-4-ones 1–8 with sodamide under mild conditions was presented. …”
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Genetic characteristics and pathogenesis of clade 2.3.4.4b H5N1 high pathogenicity avian influenza virus isolated from poultry in South Korea, 2022–2023 by Ra Mi Cha, Min-Ji Park, Yoon-Gi Baek, Yu-Na Lee, Yunyueng Jang, Yong-Myung Kang, Gyeong-Beom Heo, Se-Hee An, Kwang-Nyeong Lee, Jae-Kyeom Kim, Hye-Ryoung Kim, Youn-Jeong Lee, Eun-Kyoung Lee

“…During the 2022–2023 winter season in South Korea, a novel clade 2.3.4.4b H5N1 HPAIV was first detected in wild birds, which then subsequently caused multiple outbreaks in poultry farms and wild birds. …”
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The crystal structure of dichlorido-bis(3-methyl-3-imidazolium-1-ylpropionato-κ2)-cadmium(II), C14H20CdCl2N4O4 by Yang Fei, Wang Zongwei, Liu Pengju, Guo Libing, Xian Dong

“…C14H20CdCl2N4O4, monoclinic, P21/n (no. 14), a = 8.261(3) Å, b = 16.390(5) Å, c = 13.967(4) Å, β = 95.850(4)°, V = 1881.3(10) Å3, Z = 4, Rgt(F) = 0.0342, wRref(F2) = 0.0873, T = 296 K.…”
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The Adducts Lipid Peroxidation Products with 2′-DeoxyNucleosides: A Theoretical Approach of Ionisation Potential by Boleslaw T. Karwowski

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Eugenol targeting CrtM inhibits the biosynthesis of staphyloxanthin in Staphylococcus aureus by Jiang Chang, Bo Chen, Zeqian Du, Bowen Zhao, Jiahui Li, Ziyi Li, Kannappan Arunachalam, Ting Shi, Dongqing Wei, Chunlei Shi

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Equilibrium Adsorption of Organic Compounds (Nitrobenzene Derivative, Synthetic Pesticide, Dye, and Surfactant) on Activated Carbon from Single- and Multi-Component Systems by Magdalena Blachnio, Malgorzata Zienkiewicz-Strzalka, Anna Derylo-Marczewska

Subjects: “…4-chlorophenoxyacetic acid…”
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Role of interleukin-4 receptor α polymorphism in patients with asthma and its correlation with asthma severity by Nidhi Girdhar, Karan Sharma, Satyajit Deshpande, Siddharth Sharma, Vishal Chopra, Anil Sontakke

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Adoption of drone, sensor, and robotic technologies in organic farming systems of Visegrad countries by Bojana Petrovic, Yevhen Kononets, László Csambalik

Subjects: “…V4 countries…”
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Crystal structure of 3-(3-bromophenyl)-1′,3′-dimethyl-2′H,3H,4H-spiro[furo[3, 2-c]chromene-2,5′-pyrimidine]-2′,4,4′,6′(1′H,3′H) tetraone, C22H15BrN2O6 by Jiang Dong-Li, Fan Lian-Lian, Yin Peng, Liang Di, Li Rui

“…C22H15BrN2O6, monoclinic, P21/c (No. 14), a = 5.1760 (5) Å, b = 17.5652(19) Å, c = 21.734(2) Å, β = 94.690(3) °, Z = 4, V = 1969.3(3) Å3, Rgt(F) = 0.0569, wRref(F2) = 0.1206, T = 170 K.…”
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Crystal structure of (2R,3S,4S,5R,6S)-2-(acetoxymethyl)-6-((1-acetyl-5-bromo-4-chloro-1H-indol-3-yl)oxy)tetrahydro-2H-pyran-3,4,5-triyl triacetate hemihydrate C24H25BrClNO11 by Liu Yucong, Wang Pingqiao, Ding Haixin

“…C24H25BrClNO11, monoclinic, C2 (no. 5), a = 28.914(5) Å, b = 7.9349(14) Å, c = 13.062(2) Å, β = 114.867(3)°, V = 2718.9(8) Å3, Z = 4, Rgt(F) = 0.0352, wRref(F2) = 0.0888, T = 296.15 K.…”
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