Antifibrotic Effect of Combination of Nilotinib and Stem Cell-Conditioned Media on CCl4-Induced Liver Fibrosis by Gamal Shiha, Ahmed Nabil, Ahmed Lotfy, Reham Soliman, Ayman A. Hassan, Islam S. Ali, Doaa F. Gad, Faten Zahran

“…This study was carried out to examine the antifibrotic effect of Nilotinib and stem cell exosomes on CCl4-induced liver fibrosis in rats. Male Wistar rats were injected intraperitoneally with CCl4 twice a week for 9 weeks and given daily treatments of Nilotinib (20 mg/kg), stem cell exosomes (0.5 ml/rat), and the combination treatment of Nilotinib and stem cell exosomes during the last 5 weeks of CCl4 intoxication. …”
Get full text

On the number of representations of positive integers by quadratic forms as the basis of the space S4(Γ0(47),1) by Ahmet Tekcan, Osman Bızım

“…The number of representations of positive integers by quadratic forms F1=x12+x1x2+12x22 and G1=3x12+x1x2+4x22 of discriminant −47 are given. Moreover, a basis for the space S4(Γ0(47),1) are constructed, and the formulas for r(n;F4), r(n;G4), r(n;F3⊕G1), r(n;F2⊕G2), and r(n;F1⊕G3) are derived.…”
Get full text

Unusual Findings of Human-Associated Four-Nucleated <i>Entamoeba</i> Species in Captive Wild Animals by Lorena Esteban-Sánchez, Juan José García-Rodríguez, Francisco Ponce-Gordo

“…Several species of amoebae in the genus <i>Entamoeba</i> forming four-nucleated mature cysts are pathogenic, but their identification is challenging due to a lack of distinctive morphological traits. …”
Get full text

Multiple Periodic Solutions of Delayed Predator-Prey Systems with Type IV Functional Responses on Time Scales by Shengbin Yu, Haihui Wu, Jiangbin Chen

“…With the help of a continuation theorem based on Gaines and Mawhin's coincidence degree, easily verifiable criteria are established for the existence of multiple positive periodic solutions of delayed predator-prey systems with type IV functional responses on time scales. Our results not only unify the existing ones but also widen the range of applications.…”
Get full text

新的具有大线性复杂度的4值低相关序列集 by 陈俊, 唐小虎, 陈运, 吴震

Get full text

Deep learning–based assessment of missense variants in the COG4 gene presented with bilateral congenital cataract by Shaohua Zhang, Yang Sun, Yinghong Ji, Li Ning, Binghe Xiao, Maierdanjiang Ainiwaer, Houyi Liu, Yingying Hong

“…Objective We compared the protein structure and pathogenicity of clinically relevant variants of the COG4 gene with AlphaFold2 (AF2), Alpha Missense (AM), and ThermoMPNN for the first time.Methods and analysis The sequences of clinically relevant Cog4 missense variants (one novel identified p.Y714F and three pre-existing p.G512R, p.R729W and p.L769R from Uniprot Q9H9E3) were imported into AF2 for protein structural prediction, and the pathogenicity was estimated using AM and ThermoMPNN. …”
Get full text

A Novel Analytical Method for Trace Ammonium in Freshwater and Seawater Using 4-Methoxyphthalaldehyde as Fluorescent Reagent by Ying Liang, Yingming Pan, Qing Guo, Hongzhi Hu, Chancui Wu, Qian Zhang

“…A novel fluorescent reagent for determination of ammonium, 4-methoxyphthalaldehyde (MOPA), was successfully synthesized in this study. …”
Get full text

CD4 Cell Counts at HIV Diagnosis among HIV Outpatient Study Participants, 2000–2009 by Kate Buchacz, Carl Armon, Frank J. Palella, Rose K. Baker, Ellen Tedaldi, Marcus D. Durham, John T. Brooks

“…Background. It is unclear if CD4 cell counts at HIV diagnosis have improved over a 10-year period of expanded HIV testing in the USA. …”
Get full text

Electrolyte and Interphase Chemistry for 4.6-V Lithium Metal Batteries Operated below −30 °C by Zhongsheng Wang, Chunlei Zhu, Jiandong Liu, Shihan Qi, Jianmin Ma

“…The dual interphases with a LiPO2F2 additive could accelerate Li+ migration, reduce impedance, prevent electrolyte consumption, alleviate cathode degradation, and even mitigate the severe polarization of the Li anode at −50 °C. As a result, a 4.6-V Li||NCM811 cell with an optimized electrolyte sustained 160 cycles before reaching the 80% threshold and sustained a 92% capacity retention rate (139.9 mAh g−1) at 20 mA g−1/−30 °C after 50 cycles. …”
Get full text

Upper and Lower Solution Method for Fourth-Order Four-Point Boundary Value Problem on Time Scales by Ilkay Yaslan Karaca

“…We consider a fourth-order four-point boundary value problem for dynamic equations on time scales. …”
Get full text

Quantum-Ordering Ambiguities in Weak Chern—Simons 4D Gravity and Metastability of the Condensate-Induced Inflation by Panagiotis Dorlis, Nick E. Mavromatos, Sotirios-Neilos Vlachos

Get full text

Creativity in numbers: Uncovering students' potential through diagnostic learning evaluation at SMK Pasundan 4 Bandung by Ainil Kaafil Hasanah, Lulu Banusalam, Muhammad Rizqi Febrian

“…This research shows that diagnostic learning evaluation with a creative approach can transform the learning paradigm at SMK Pasundan 4 Bandung. SMK Pasundan 4 Bandung can produce graduates ready to face the ever-changing business world by involving students in the evaluation process and harnessing modern technology.…”
Get full text

Solution of Motion Position and Machining Simulation for Spiral Bevel Gear based on Four Axis Generative Movement by Ganglei Lü, Jun Liu, Zhengying Liu

“…Abstract Aiming to develop economical and practical milling machine， and reduce the production cost of spiral bevel gear， the processing method based on four axis milling machine is proposed. Firstly， the machine model of four axis milling machine is established， and the processing motion is analyzed. …”
Get full text

A Comparison of Two Land Use Simulation Models under the RCP4.5 Scenario in China by Feng Wu, Jinyan Zhan, Qian Xu, Yihui Xiong, Zhongxiao Sun

Get full text

Expression and localization of two β-carbonic anhydrases in Bienertia, a single-cell C4 plant by Tho Nguyen, Nakyoung Lee, Fabian J. Frömling, Toni L. Meister, Toni L. Meister, Toni L. Meister, Jung Sun Kim, Sascha Offermann, Inhwan Hwang

“…Here, we characterized at the molecular, cellular and biochemical levels two β-type CAs in Bienertia sinuspersici, a plant that operates a C4 carbon concentrating mechanism within individual cells without the Kranz anatomy. …”
Get full text

Cognitively Stimulating Activities: Effects on Cognition across Four Studies with up to 21 Years of Longitudinal Data by Meghan B. Mitchell, Cynthia R. Cimino, Andreana Benitez, Cassandra L. Brown, Laura E. Gibbons, Robert F. Kennison, Steven D. Shirk, Alireza Atri, Annie Robitaille, Stuart W. S. MacDonald, Magnus Lindwall, Elizabeth M. Zelinski, Sherry L. Willis, K. Warner Schaie, Boo Johansson, Roger A. Dixon, Dan M. Mungas, Scott M. Hofer, Andrea M. Piccinin

“…Using observational studies of naturalistic cognitive activities, we report a series of mixed effects models that include baseline and change in cognitive activity predicting cognitive outcomes over up to 21 years in four longitudinal studies of aging. Consistent evidence was found for cross-sectional relationships between level of cognitive activity and cognitive test performance. …”
Get full text

Knowledge, Attitude, and Practices (KAP) of Human Populations towards Malaria Control in Four Ecoepidemiological Settings in Cameroon by Nelly Armanda Kala Chouakeu, Laura Gilberine Ngingahi, Roland Bamou, Abdou Talipouo, Carmen Sandra Ngadjeu, Marie Paul Audrey Mayi, Edmond Kopya, Parfait Awono-Ambene, Timoléon Tchuinkam, Christophe Antonio Nkondjio

“…The present study seeks to assess the knowledge, attitude, and practices (KAP) of populations towards malaria prevention in four ecoepidemiological settings in Cameroon. A cross-sectional malaria KAP survey was conducted from August to September 2019 in households of the localities of Kaélé, Tibati, Bertoua, and Santchou. …”
Get full text

Scutellarein Inhibits Osteosarcoma Growth by Targeting the TLR4/TRAF6/NF-&kappa;B Pathway by Shi Y, Tang Y, Sun Z, Sui P, Shao Y, Wang Z, Zhang J, Gao M

Subjects: Get full text

A 7-nm-Based 5R4W High-Timing Reliability Regfile Circuit by Wanlong Zhao, Yuejun Zhang, Liang Wen, Pengjun Wang

“…To address the read/write conflict and timing error problems of register heap, this paper proposes a 5R4W high-timing reliability Regfile circuit design scheme. …”
Get full text

MADONNA’S FOUR-DECADE INFLUENCE: BRAND STRATEGY AND GLOBAL IMPACT OF THE CELEBRATION TOUR RIO DE JANEIRO by Pedro BELTRÁN CUERVO, Cecilia VALLEJOS PARÁS

Get full text