Machine learning-powered, high-affinity modification strategies for aptamers by Gubu Amu, Xin Yang, Hang Luo, Sifan Yu, Huarui Zhang, Yuan Tian, Yuanyuan Yu, Shijian Ding, Yufei Pan, Zefeng Chen, Yixin He, Yuan Ma, Baoting Zhang, Ge Zhang

“…In the current study, an interactive methodology involving the exchange of mutual information between experimental endeavors and machine learning was initially proposed to design a high-affinity post-SELEX modification strategy for aptamers. After four rounds of interactive training (a total of 422 modified aptamer-target affinity datasets with diverse modification types and sites), an antifcial intelligence model with high predictive accuracy with a correlation coefficient of 0.82 between the predicted and actual binding affinities was obtained. …”
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Investigating the Influence of Process Parameters of ZNC EDM on Machinability of A6061/10% SiC Composite by Balbir Singh, Jatinder Kumar, Sudhir Kumar

“…The composite has been experimentally investigated for its machinability using Z-axis numerically controlled (ZNC) electrodischarge machining (EDM) process. The effects of the four process parameters, namely, current, gap voltage, pulse-on time, and pulse-off time are investigated on material removal rate (MRR), tool wear rate (TWR), and surface roughness (SR) by varying one parameter at a time approach. …”
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A New Method Based on Operational Strategies for Early Detection of Breast Cancers by Samira Khajehkhasan, Soheil Fakheri

“…This article proposes an algorithm for diagnosing breast cancer that includes four steps. The first stage is the preprocessing stage; the second stage is for image analysis, which uses wavelet transform to analyze images; the third stage is the extraction of valuable features that we use the results of wavelet transform to obtain; and the fourth stage That is, we use fuzzy logic to identify two types of benign or malignant images. …”
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Prediction of PM2.5 via precursor method using meteorological parameters by Naeem Sadiq, Zaheer Uddin

“…The model consists of an input layer with four input variables, a hidden layer with 10 neurons, and an output layer consisting of  PM2.5. …”
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Review of the Influence of non-singular higher order terms on the stress field of thin welded lap joints and small inclined cracks in plates by F. Berto, M.R. Ayatollahi, S. Vantadori, A. Carpinteri

“…The present paper indicates that the local stresses as well as the strain energy averaged over a control volume which embraces the slip tip, can be evaluated with satisfactory precision only by taking into account a further four terms besides KI, KII and T-stress.…”
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Measuring spatial - temporal of Yazd urban form using spatial metrics by saeed zanganeh

“…The conclusion revealed that in four periods of study, complexity or irregularity of the urban patch shapes has increased, centrality or average distance of the dispersed parts to the city center has decreased, compactness or the number and area of patches their distance from each other has decreased, porosity or ratio of open space has increased and finally population density of city has decreased in a large amount. …”
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Deep Learning for Predicting Spheroid Viability: Novel Convolutional Neural Network Model for Automating Quality Control for Three-Dimensional Bioprinting by Zyva A. Sheikh, Oliver Clarke, Amatullah Mir, Narutoshi Hibino

“…The model was trained to automatically classify spheroids into one of four distinct categories based on their predicted viability: 0–20%, 20–40%, 40–70%, and 70–100%. …”
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Development and psychometric evaluation of the ethical conflict assessment instrument in nursing: A mixed-method protocol study by Ebrahim Falahati, Mousa Alavi, Mohsen Shahriari

“…MATERIALS AND METHODS: This is an exploratory mixed-method study that will be conducted using a sequential qualitative–quantitative design (QUAL → quan) consisting of four sequential phases to develop the instrument. …”
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Fluctuations in Seminal Quality throughout the Year: How do Temperature, Humidity and Atmospheric Pressure Impact on Human Sperm Quality? by Nicolás David Ramírez, Andrea Tissera, Rosa Molina, Jose Olmedo, Héctor Guillermo Molina, Arnaldo Mangeaud, Ana Carolina Martini

“…Materials and Methods: Patients (n: 15665) were categorised into four groups (summer, winter, spring and autumn) according to the date of assistance at the fertility centre. …”
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Diversity across Seasons of Culturable Pseudomonas from a Desiccation Lagoon in Cuatro Cienegas, Mexico by Alejandra Rodríguez-Verdugo, Valeria Souza, Luis E. Eguiarte, Ana E. Escalante

“…We sampled Pseudomonas populations from a seasonally variable water system at four different sampling dates (August 2003, January 2004, January 2005, and August 2005). …”
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Variants and social interaction: A study of the Acehnese Daya Dialect by Teuku Alamsyah, Razali Razali, Teuku Munawar, Ramli Ramli

“…Data collection involved observation and interviews, with data analysis conducted using the interactive model analysis, which includes four stages: data reduction, data categorization, data presentation, and conclusion. …”
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Factors Improvement of Sustainable livelihoods from the Perspective of Local People, Case Study: Ardabil County by vakil heidari sarban, Alireza Abdpour

“…In order to analyze the data, factor analysis model was used and the results of this model showed the most important factor improvement of sustainable livelihoods from the perspective of local people in studied region includes four components (entrepreneurship and fortification of economical infrastructures, support of demand- side and governmental interventional action, fortification of social capital and social empowerment and environmental management and fortification of physical infrastructures) that explained variance and the cumulative variance by the five factors 60.66. …”
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Are doctors feeling burnout? – Multicenter cross-sectional study on burnout syndrome and its determinants during the ongoing pandemic by Ashutosh Kumar, Kavita Chawla, Arun Mishra, Geetu Singh, Achyut K. Pandey, Praveen Rikhari

“…Materials and Methods: This was a multicentric cross-sectional study that included medical faculty from four tertiary care government teaching hospitals in north India. …”
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Coupling Coordination Degree Measurement and Forecast of Poverty Alleviation, Energy Conservation, and Ecological Protection: Evidence from 30 Provinces and Cities in China by Shuai Guan, Qichun Zhang

“…Third, in the following years, development level will still be on an upwards trend in the four regions of China from 2020 to 2025. The development level of the ecological protection system will be the highest in China, and poverty alleviation and energy conservation will rank second and third. …”
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Unequal weathering: How immigrants’ health advantage vanishes over the life-course by Silvia Loi, Peng Li, Mikko Myrskylä

“…This paper aims at contributing to this strand of research by addressing four research questions: is the health of immigrants declining at a faster pace over the life-course, compared to non-immigrants? …”
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Controlled Capture of Magnetic Nanoparticles from Microfluidic Flows by Ferromagnetic Antidot and Dot Nanostructures by Reyne Dowling, Mikhail Kostylev

“…In this paper, we demonstrate the capture of magnetic nanoparticles from a microfluidic flow by four variants of antidot array nanostructures etched into 30 nm thick Permalloy films. …”
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Phenotypic Diversity Assessment of Okra (Abelmoschus Esculentus (L.) Moench) Genotypes in Ethiopia Using Multivariate Analysis by Jemal Mohammed, Wassu Mohammed, Eleni Shiferaw

“…The 36 genotypes were grouped into four distinct clusters from the Euclidean distance matrix using the unweighted pair group method with arithmetic mean (UPGMA). …”
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Exploring the relationship between corporate governance and firm value: evidence from LQ45 companies (2010-2014) by David David, Setyani Dwi Lestari, Adi Saputro

“…However, simultaneously, the four variables have a significant impact on firm value, with probability values below 0.05, indicating that these factors work together in influencing firm value. …”
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FIKHULLUGA VE İLMULLUGA TERİMLERİNİN ANLAMLARI / THE MEANINGS OF THE FIKHULLUGA AND THE ILMULLUGA TERMS by Mahmut KAFES

“…Fıkhulluga terimi Arap edebiyatında ilk defa IV./X. yüzyılda, ikinci defa da XX. yüzyılın ortalarında ortaya çıkmıştır. …”
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Breast Diffuse Large B-cell Lymphoma, Activated B-cell like Subtype: A Case Report by Sneha Samir Babaria, Jinalben Shaileshbhai Patel

“…By sharing this case, authors aimed to contribute to the growing knowledge of this rare entity, which has steadily increased over the past four decades, to ensure timely and accurate diagnosis for the implementation of appropriate therapy.…”
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