Role of Insulin-Like Growth Factor Binding Protein-3 in 1, 25-Dihydroxyvitamin-D3-Induced Breast Cancer Cell Apoptosis by C. Brosseau, G. Pirianov, K. W. Colston

“…Insulin-like growth factor I (IGF-I) is implicated in breast cancer development and 1, 25-dihydroxyvitamin D3 (1, 25-D3) has been shown to attenuate prosurvival effects of IGF-I on breast cancer cells. …”
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Synthesis and Antidepressant Activity of Some New 5-(1H-Indol-3-yl)-3-(substituted aryl)-4,5-dihydroisoxazoline Derivatives by Pravin O. Patil, Sanjay B. Bari

“…The antidepressant activity of the synthesized compounds (3a–3n) was evaluated by forced swim test in mice and their locomotor activity was assessed using actophotometry. …”
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Shuyu Capsules Relieve Premenstrual Syndrome Depression by Reducing 5-HT3AR and 5-HT3BR Expression in the Rat Brain by Fang Li, Jizhen Feng, Dongmei Gao, Jieqiong Wang, Chunhong Song, Sheng Wei, Mingqi Qiao

“…The effects of the Shuyu capsule on 5-HT3AR and 5-HT3BR expression in a rat model of premenstrual syndrome (PMS) depression and on 5-HT3AR and 5-HT3BR expression and hippocampal neuron 5-HT3 channel current were investigated, to elucidate its mechanism of action against PMS depression. …”
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Deciphering molecular and cellular ex vivo responses to bispecific antibodies PD1-TIM3 and PD1-LAG3 in human tumors by Alfred Zippelius, Petra Herzig, Pratiksha Gulati, Christian Klein, Marta Trüb, Kirsten D Mertz, Robert Rosenberg, Viola Heinzelmann-Schwarz, Mark Wiese, Didier Lardinois, Pablo Umana, Marina Natoli, Klas Hatje, Fabian Junker, Zhiwen Jiang, Iakov I Davydov, Markus Germann, Daniel Marbach, Adrian Zwick, Patrick Weber, Stefan Seeber, Lothar Tietze, Laura Codarri-Deak, Henry Kao

“…Background Next-generation cancer immunotherapies are designed to broaden the therapeutic repertoire by targeting new immune checkpoints including lymphocyte-activation gene 3 (LAG-3) and T cell immunoglobulin and mucin-domain containing-3 (TIM-3). …”
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PRL-3调节PI3K信号通路在促进结肠癌细胞增殖侵袭中的作用

Subjects: “…肝再生磷酸酶-3…”
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NEIL3 Mediates Lung Cancer Progression and Modulates PI3K/AKT/mTOR Signaling: A Potential Therapeutic Target by Hongbo Huang, Qingwang Hua

“…Nei endonuclease VIII-like 3 (NEIL3) is widely involved in pathophysiological processes of the body; however, its role in lung cancer has not been conclusively determined. …”
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NLRP3 inflammasome-modulated angiogenic function of EPC via PI3K/ Akt/mTOR pathway in diabetic myocardial infarction by Jia-Peng Li, Shu Qiu, Guang-Jie Tai, Yi-Ming Liu, Wei Wei, Meng-Meng Fu, Pan-Qi Fang, Joseph Nicolao Otieno, Tungalag Battulga, Xiao-Xue Li, Ming Xu

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Transdifferentiation of rat keratinocyte progenitors to corneal epithelial cells by limbal niche via the STAT3/PI3K/AKT signaling pathway by Bei Wang, Jiang-Lan Zhao, Gong-Yue Wang, Wan-Ying Cai, Yu-Ting Xiao, Jia-Song Wang, Chao Wang, Yu-Zhi Li, Xi Peng, Tian-Yu Yao, Ming-Chang Zhang, Hua-Tao Xie

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La reconstitution 3D du chevet de Cluny III : clôture de chœur, stalles, pavement, peintures murales et vitraux by Juliette Rollier-Hanselmann, Guillaume Schotté, Jérémie Landrieu, Nicolas Poupart, avec la collaboration de Françoise Perrot et Brigitte Maurice-Chabard 1

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Single-cell RNA sequencing reveals intrahepatic signature related to pathobiology of duck hepatitis A virus type 3 (DHAV-3) infection by Yunsheng Zhang, Dingbang Ding, Shaofei Li, Qiong Pan, Jinlong Ru, Haonan Zhao, Guang Yao, Jie Wei, Shuaiqin Wang, Shuisheng Hou, Xia Wang

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Comparative Analysis of the Occurrence and Role of CX3CL1 (Fractalkine) and Its Receptor CX3CR1 in Hemophilic Arthropathy and Osteoarthritis by Piotr Wojdasiewicz, Łukasz A. Poniatowski, Andrzej Kotela, Marta Skoda, Michał Pyzlak, Aleksandra Stangret, Ireneusz Kotela, Dariusz Szukiewicz

“…Hemophilic arthropathy is characterized by recurrent bleeding episodes in patients with hemophilia leading to irreversible joint degeneration. The involvement of CX3CL1 (fractalkine) and its receptor CX3CR1 was observed in the pathogenesis of numerous arthritis-associated diseases. …”
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Enhanced UV–Vis Rejection Ratio in Metal/BaTiO3/β‐Ga2O3 Solar‐Blind Photodetectors by Nathan Wriedt, Lingyu Meng, Dong Su Yu, Chris Chae, Kyle Liddy, Ashok Dheenan, Sushovan Dhara, Roberto C. Myers, Oleg Maksimov, Richard Blakeley, Sanjay Krishna, Jinwoo Hwang, Hongping Zhao, Joe McGlone, Siddharth Rajan

Subjects: “…BaTiO3…”
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Synthesis and luminescence properties of Na3SrB5O10:Eu3+ glass samples for solid-state lighting application by Amruta Gaikwad, Yatish R. Parauha, Kamlesh V Dabre, S.J. Dhoble

“…Borate materials are very beneficial for optical materials due to its wide transparency range, huge electronic band gap, thermal and chemical durability, low preparative temperature, and high optical damage threshold. Na3SrB5O10 glasses were synthesized through a melt quenching technique followed by a sintering process, incorporating various concentrations of Eu3+ ions. …”
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PTEN depletion reduces H3K27me3 levels to promote epithelial-to-mesenchymal transition in epithelial colorectal cancer cells. by Ahmed H Ghobashi, Jane W Kimani, Christopher A Ladaika, Heather M O'Hagan

“…Interestingly, PTEN KD reduced the global levels of trimethylation of histone 3 at lysine 27(H3K27me3) in an EZH2-phosphorylation-dependent manner. …”
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ENGINEERING THE NaYF4:Yb3+/Tm3+ UPCONVERSION NANOPARTICLE LUMINESCENCE ENERGY TRANSFER FOR A RATIOMETRIC pH INDICATOR by Nhat Nam Nguyen

“…Fluorescent dye 8-hydroxypyrene-1,3,6-trisulfonic acid (HPTS) is used to develop a ratiometric pH indicator based on NaYF4:Yb3+/Tm3+ upconversion nanoparticles (UCNPs). …”
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lncRNA NORAD modulates STAT3/STAT1 balance and innate immune responses in human cells via interaction with STAT3 by Amir Argoetti, Dor Shalev, Galia Polyak, Noa Shima, Hadas Biran, Tamar Lahav, Tamar Hashimshony, Yael Mandel-Gutfreund

“…In NORAD-deficient cells, STAT3 remains cytoplasmic, allowing STAT1 to enhance antiviral activity. …”
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Novel Catalyst-Free Synthesis of Some 3‑Alkylaminoquinoxaline-2(1H)‑thiones and 3‑Alkyloxyquinoxaline-2(1H)‑thiones in Ethanol by Samir M. El Rayes, Ibrahim A. I. Ali, Walid Fathalla, Mohamed A. Ghanem, Afaf H. El-Sagheer

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Engineered T cells secreting αB7-H3-αCD3 bispecific engagers for enhanced anti-tumor activity against B7-H3 positive multiple myeloma: a novel therapeutic approach by Punchita Rujirachaivej, Teerapong Siriboonpiputtana, Kornkan Choomee, Kamonlapat Supimon, Thanich Sangsuwannukul, Pucharee Songprakhon, Krissada Natungnuy, Piriya Luangwattananun, Pornpimon Yuti, Mutita Junking, Pa-thai Yenchitsomanus

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Synthesis and crystal structure of 1-(7-hydroxy-3-(4-hydroxy-3-nitrophenyl)-4-oxo-4H-chromen-8-yl)-N,N-dimethylmethanaminiumnitrate, C18H17N3O9 by Chen Hai-Lin, Yao Dong-Mei, Luo Ze-Ping, Wang Yan-Ping, Tang Yu-Mei

“…C18H17N3O9, monoclinic, P21/c (no. 14), a = 15.3768(3) Å, b = 7.4510(2) Å, c = 15.6673(5) Å, β = 102.700(3)∘, V = 1751.13(8) Å3, Z = 4, Rgt(F) = 0.0405, wRref(F2) = 0.1157, T = 100 K.…”
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Synthesis and crystal structure of (S,E)-4-hydroxy-3-(2-((4aR,6aS,7R,10aS,10bR)-3,3,6a,10b-tetramethyl-8-methylenedecahydro-1H-naphtho[2,1-d][1,3]dioxin-7-yl)ethylidene)dihydrofuran-2(3H)-one, C23H34O5 by Li Shi-Qing, Zhou Jian, Dong Zhang-Chao, Pan Bo Wen, Shi Yang, Zhou Ying

“…C23H34O5, orthorhombic, P212121 (no. 19), a = 11.1838(3) Å, b = 11.7824(3) Å, c = 16.3160(5) Å, V = 2149.99(10) Å3, Z = 4, Rgt ${R}_{\mathrm{g}\mathrm{t}}$ (F) = 0.0399, wRref $w{R}_{\mathrm{r}\mathrm{e}\mathrm{f}}$ (F 2) = 0.1097, T = 293 K.…”
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