Three-dimensional (3D) augmented reality during Retzius-sparing robot-assisted radical prostatectomy (RS-RARP): First experience by Silvia Secco, Alberto Olivero, Stefano Tappero, Paolo Dell’Oglio, Luca Carbonaro, Alessandro Marando, Angelo Vanzulli, Emanuela Bonoldi, Aldo Massimo Bocciardi, Antonio Galfano

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Effect of H2O2 induced oxidative stress on volatile organic compounds in differentiated 3T3-L1 cells by Adebowale Samuel Oyerinde, Vaithinathan Selvaraju, Melissa Boersma, Jeganathan Ramesh Babu, Thangiah Geetha

“…The objective is to investigate the impact of OS on cell metabolism by analyzing the release or alterations of VOCs in the headspace of differentiated 3T3-L1 adipocytes. An OS model in differentiated 3T3-L1 cell lines was constructed using hydrogen peroxide (H2O2) treatment. …”
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Palladium-Catalyzed C(sp3)-H Arylation of Benzo[b]thiophen-3(2H)-one 1,1-Dioxide by Hailong Liu, Wenjing Li, Haiyan Fu, Hua Chen, Ruixiang Li, Yu Li

“…A new concise synthesis route of 2-phenylbenzo[b]thiophen-3(2H)-one 1,1-dioxide from benzo[b]thiophen-3(2H)-one 1,1-dioxide was developed using palladium-catalyzed C(sp3)-H arylation. …”
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LINC01271 promotes fracture healing via regulating miR-19a-3p/PIK3CA axis by Qinghua Chen, Lina Huang, Wenjun Ji, Miao Huang, Jincheng Sima, Jin Li, Hao Song, Wei Xiong, Bin Chen

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Synthesis of New (E)-2-(1H-Indole-3-ylcarbonyl)-3-heteroaryl-acrylonitriles via Microwave-Assisted Knoevenagel Condensation by Adriana V. Treuer, Pedro De-La-Torre, Margarita I. Gutiérrez

“…We report a stereoselective synthesis of a series of new (E)-2-(1H-indole-3-ylcarbonyl)-3-heteroaryl-acrylonitriles (3a–3i) obtained from 3-(cyanoacetyl)indole and heteroaryl-aldehydes under microwave-assisted Knoevenagel reaction at 300 W of potency and 100°C. …”
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A TRAILR2/CDH3 bispecific antibody demonstrates selective apoptosis and tumor regression in CDH3-positive pancreatic cancer by Peter Jung, Stefan P. Glaser, Jing Han, Alexandra Popa, Laura Pisarsky, Ningping Feng, Antonia Geyer, Franziska Haderk, Donat Alpar, Christopher Bristow, Susanne Schmittner, Paula-Elena Traexler, Mikhila Mahendra, Birgit Poehn, Poojabahen Gandhi, Roberto Fiorelli, Sanket Awate, Nicole Budano, Florian Martin, Christoph Albrecht, Barbara Drobits-Handl, Sathanandam S. Anand, Srinath Kasturirangan, Francesca Trapani, Norbert Schweifer, Joseph R. Marszalek, Ulrike Tontsch-Grunt, Mark Pearson, Timothy P. Heffernan, Norbert Kraut, Christopher P. Vellano, Juan Manuel García-Martínez

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Synthesis, Antibacterial, Antioxidant, and Molecular Modeling Studies of Novel [2,3′-Biquinoline]-4-Carboxylic Acid and Quinoline-3-Carbaldehyde Analogs by Zeleke Digafie, Yadessa Melaku, Zerihun Belay, Rajalakshmanan Eswaramoorthy

“…Hence, this project aims to design, synthesize, and evaluate their antibacterial and antioxidant activities of new series of [2,3′-biquinoline]-4-carboxylic acid and quinoline-3-carbaldehyde analogs. …”
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The Role of Quercetin and Exercise in Modulating Apoptosis and Cardiomyopathy via PI3K/AKT/FOXO3 Pathways in Diabetic Obese Rats by Mojdeh Khajehlandi, Lotfali Bolboli

“…In addition, bothtraining protocols showed potentially successful diabetic cardiomyopathy treatments through modulating the FOXO3and PI3K/AKT pathways.…”
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Inhibition of the PERK/TXNIP/NLRP3 Axis by Baicalin Reduces NLRP3 Inflammasome-Mediated Pyroptosis in Macrophages Infected with Mycobacterium tuberculosis by Yan Fu, Jingjing Shen, Yinhong Li, Fanglin Liu, Bangzuo Ning, Yuejuan Zheng, Xin Jiang

“…In conclusion, baicalin reduced pyroptosis by inhibiting the PERK/TXNIP/NLRP3 axis and might thus be a new adjuvant host-directed therapy (HDT) drug.…”
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Evaluation and Measurement of Health-Related Quality of Life for Individuals with Diabetes Mellitus by Health Utilities Index Mark 3 (HUI3) System by Frank Mo, Howard Morrison, Bernard C.K. Choi, Lianne Vardy

“…The Health Utilities Index Mark 3 (HUI3) is an important indicator when measuring the health-related quality of life (HRQOL) and assessing the burden of disease, especially for chronic conditions such as diabetes mellitus (DM). …”
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Inhibition of Horseradish Peroxidase Activity by Boroxine Derivative, Dipotassium-trioxohydroxytetrafluorotriborate K2[B3O3F4OH] by Jelena Ostojic, Safija Herenda, Semira Galijasevic, Borivoj Galic, Mladen Milos

“…Thus, the inhibition of HRP activity by dipotassium-trioxohydroxytetrafluorotriborate K2[B3O3F4OH] was investigated for possible explanation of previously observed antitumour activities of this promising drug. …”
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Sintering-induced multiferroicity in 0.93(NaBi)TiO3–0.07BaTiO3 ceramics by Hongbo Liu, Jianguo Chen

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3D-QSAR Study on a Series of VEGFR-2 Kinase Inhibitors: 3-Pyrrole Substituted Indolin-2-Ones Compounds by Shunlai Li, Rutao Zhang, Hongguang Du

“…Self-organizing molecular field analysis (SOMFA) (a simple three-dimensional quantitative structure-activity relationship (3D-QSAR) method) is used to study the structure-activity correlation of 3-pyrrole substituted indolin-2-ones VEGFR-2 inhibitors. …”
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3D Printing/Additive Manufacturing Single Titanium Dental Implants: A Prospective Multicenter Study with 3 Years of Follow-Up by Samy Tunchel, Alberto Blay, Roni Kolerman, Eitan Mijiritsky, Jamil Awad Shibli

“…This prospective 3-year follow-up clinical study evaluated the survival and success rates of 3DP/AM titanium dental implants to support single implant-supported restorations. …”
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SCO6564, a novel 3-ketoacyl acyl carrier protein synthase III, contributes in fatty acid synthesis in Streptomyces coelicolor. by Jian-Rong Ma, Jia-Ying Lin, Yuan-Yin Zhang, Yun Chen, Wen-Bing Zhang, Xian-Pu Ni, Yong-Hong Yu

“…Fatty acid synthesis has been intensively studied in the model strain Streptomyces coelicolor, in which 3-ketoacyl-acyl carrier protein synthase III (KAS III, FabH) is essential for growth and fatty acid biosynthesis. …”
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Promising Response with PI3K Inhibitor for a Patient with Heavily Pretreated PIK3CA Mutation Head-and-Neck Cancer by Ming-Jing Lee, Hsiang-Fong Kao

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两种不同来源的EBV LMP1 基因在Balb/c 3T3 细胞中的表达 by 陈　元, 郭辉玉, 方丹云, 晏辉钧

“…【目的】研究来源于鼻咽癌细胞株SUNE1 及EBV 标准株B95 -8 细胞中两种EBV LMP1 基因在真核细胞Balb/c 3T3 中的表达, 为进一步研究EBV LMP1 基因的核酸疫苗打基础。【方法】将两种不同来源EBV LMP1 基因的真核表达质粒, 经 脂质体法转染Balb/ c 3T3 细胞后, 用Western blot、免疫组化及PCR 的方法检测不同转染细胞中EBV LMP1 蛋白的表达及核酸片 段。…”
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Speciation Studies of Diorganotin(IV) Complexes with 3,3-Bis(1-methylimidazol-2-yl)propionate—Displacement Reaction by DNA Constituents by Mohamed M. Shoukry, Safaa S. Hassan

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H3K79me3T80ph is a Novel Histone Dual Modification and a Mitotic Indicator in Melanoma by Danielle R. Martinez, Hunter W. Richards, Qiushi Lin, Carlos A. Torres-Cabala, Victor G. Prieto, Jonathan L. Curry, Estela E. Medrano

“…The current study characterizes the mitosis-associated histone dual modification on the core of histone H3: trimethylation of histone H3 lysine 79 and simultaneous phosphorylation of H3 threonine 80 (H3K79me3T80ph). …”
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Structural insights into isoform-specific RAS-PI3Kα interactions and the role of RAS in PI3Kα activation by Daniel Czyzyk, Wupeng Yan, Simon Messing, William Gillette, Takashi Tsuji, Mitsuhiro Yamaguchi, Shinji Furuzono, David M. Turner, Dominic Esposito, Dwight V. Nissley, Frank McCormick, Dhirendra K. Simanshu

“…Abstract Mutations in RAS and PI3Kα are major drivers of human cancer. Their interaction plays a crucial role in activating PI3Kα and amplifying the PI3K-AKT-mTOR pathway. …”
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