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Glia and TRPM2 Channels in Plasticity of Central Nervous System and Alzheimer’s Diseases
Published 2016-01-01“…These results potentially point TRPM2 channel to be involved in AD through glial cells. …”
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Complex regulation of Cav2.2 N-type Ca2+ channels by Ca2+ and G-proteins.
Published 2025-01-01“…G-protein coupled receptors inhibit Cav2.2 N-type Ca2+ channels by a fast, voltage-dependent pathway mediated by Gαi/Gβγ and a slow, voltage-independent pathway mediated by Gαq-dependent reductions in phosphatidylinositol 4,5-bisphosphate (PIP2) or increases in arachidonic acid. …”
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Lack of UBE3A-Mediated Regulation of Synaptic SK2 Channels Contributes to Learning and Memory Impairment in the Female Mouse Model of Angelman Syndrome
Published 2022-01-01“…The shunting effect of SK2 channels on NMDA receptor was significantly larger in female AS mice as compared to female WT mice. …”
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Effects of Prosopis farcta Root Extract in the Vascular Reactivity of Isolated Goat Coronary Artery
Published 2019-08-01Subjects: “…Prosopis farcta, vascular reactivity, K channels, Ca 2 channels, endothelium-derived relaxing factors, endothelium derived-hyperpolarizing factor…”
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Cordycepin Decreases Compound Action Potential Conduction of Frog Sciatic Nerve In Vitro Involving Ca2+-Dependent Mechanisms
Published 2015-01-01“…However, the depressive action of cordycepin on amplitude and conductive velocity was not observed in Ca2+-free medium or in the presence of Ca2+ channel blockers (CdCl2/LaCl3). Pretreatment with L-type Ca2+ channel antagonist (nifedipine/deltiazem) also blocked cordycepin-induced responses; by contrast, T-type and P-type Ca2+ channel antagonists (Ni2+) failed to block such responses. …”
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Relationship between Ca2+ and cAMP as second messengers in ACTH-induced cortisol production in bovine adrenal fasciculata cells
Published 2023-12-01“…ACTH-induced Ca2+ influx and cortisol production were suppressed by a voltage-sensitive L-type Ca2+ channel blocker but not by a T-type, N-type, or P-type Ca2+ channel blocker. …”
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Synaptic transistor implementing potentiation or depression via field distribution modulation of dual dielectric layers by single-polarity pulsed voltage stimuli
Published 2025-03-01“…The device is fabricated using a standard complementary metal-oxide-semiconductor process and is composed of a TiO2 channel deposited over a dual dielectric of SiOx on Al2O3. …”
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Single‐ended 2 ch. × 3.4 Gbit/s dual‐mode near‐ground transmitter IO driver in 45 nm CMOS process
Published 2017-03-01“…The measured eye shows 17.8% vertically and 19.5% horizontally with finite impulse response (FIR) tap control for 15.75″ FR4 channel. The proto‐type 2 channel single‐ended driver has been implemented in 45 nm CMOS process and occupies 0.022 mm2 chip area.…”
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Phylogenetic and structural analysis of annexins in pea (<i>Pisum sativum</i> L.) and their role in legume-rhizobial symbiosis development
Published 2021-09-01“…Quantitative RT-PCR analysis showed that PsAnn4 was upregulated at the early stages of symbiosis development, starting from 1–3 days after inoculation to up to 5 days after inoculation, while experiments with the Ca2+ channel blocker LaCl3 revealed its negative influence on this expression. …”
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A Novel Rat Infant Model of Medial Temporal Lobe Epilepsy Reveals New Insight into the Molecular Biology and Epileptogenesis in the Developing Brain
Published 2024-01-01“…Several candidates, such as the low-voltage-activated Ca2+ channel Cav3.2 and the auxiliary subunits β1 and β2, which were previously reported to be upregulated in the hippocampus of the adult pilocarpine mTLE model, were found to be downregulated (together with Cav2.1, Cav2.3, M1, and M3) in the hippocampus and cortex of our InfRPil-mTLE model. …”
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Suppression of Aldosterone Synthesis and Secretion by Channel Antagonists
Published 2012-01-01“…Recently, several groups have reported that some dihydropyridine Ca2+ channel blockers (CCBs) have inhibitory actions on aldosterone production in in vitro and in the clinical setting. …”
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Development of an ISOBUS-compliant communication node for multiple machine vision systems on wide boom sprayers for nozzle control in spot application schemes
Published 2025-03-01“…The MVN consists of an electronic control unit (ECU) built around a single-board computer, equipped with a 2-channel CAN hat and an Ethernet router. The ECU utilizes AgIsoStack++ library to maintain ISOBUS compliance, enabling data exchange between the MVN and other electronic components on the sprayer. …”
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LCZ696 Therapy Reduces Ventricular Tachyarrhythmia Inducibility in a Myocardial Infarction-Induced Heart Failure Rat Model
Published 2019-01-01“…Western blot analyses showed significant downregulation of NaV1.5, ERG, KCNE1, and KCNE2 channel proteins in the HF vehicle group compared with the sham group. …”
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Exploring Magnetic Fields in Molecular Clouds through Denoising Diffusion Probabilistic Models
Published 2025-01-01“…We trained three versions of the DDPM model: the 1-channel DDPM (using only column density), the 2-channel DDPM (incorporating both column density and polarization angles), and the 3-channel DDPM (which combines column density, polarization angles, and LOS nonthermal velocity dispersion). …”
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Vasorelaxant effects and its mechanisms of the rhizome of Acorus gramineus on isolated rat thoracic aorta
Published 2025-02-01“…Since vasodilatory mechanisms associated with VSMC are predominantly influenced by K+ and Ca2+ channels, we explored various channels, including calcium-activated K+, voltage-dependent (delayed rectifier) K+, ATP-sensitive K+, inwardly rectifying K+, receptor-operated Ca2+ (ROCC), and voltage-dependent Ca2+ channels (VDCC). …”
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Suppressing Jahn-Teller distortion of MnO2 via B-Ni dual single-atoms integration for methane catalytic combustion
Published 2025-01-01“…This paper describes the integration of B-Ni dual single-atoms within MnO2 channels to serve as an electronic reservoir to direct the electron transfer route during methane catalytic combustion. …”
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Alteration of Sarcoplasmic Reticulum Ca2+ Release in Skeletal Muscle from Calpain 3-Deficient Mice
Published 2009-01-01“…Inhibition of L-type Ca2+ channels (LCC) suppressed the caffeine-induced [Ca2+]i responses in −/− myotubes. …”
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Effects of the dynamics of noise-induced calcium signals in a biophysical model of the astrocytic process
Published 2025-01-01“…The model describes the process of generation of spontaneous Ca2+ signals induced by the stochastic activation of voltage-dependent Ca2+ channels on the plasma membrane of the astrocyte. …”
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