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Sexual Differences in response to Mid- or Low-Premixed Insulin Analogue in Patients with Type 2 Diabetes
Published 2020-01-01Get full text
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Synthesis and in-situ Mo microalloying of CuCr alloy by aluminothermic self-propagating reduction
Published 2025-03-01Get full text
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Changes induced in mouse lipid metabolism by simultaneous impact of antisense oligonucleotide derivatives to <i>apoB</i>, <i>PCSK9</i>, and <i>apoCIII</i> mRNAs
Published 2020-01-01“…Triple weekly administration of these ASO combinations resulted in a decrease in non-HDL CHL by 25, 16, 35, 47, 60, and 7 %, respectively, as compared with the control and 1.8-, 1.5-, 1.9-, 2.4-, 3.1, and 1.24-fold higher HDL CHL/ non-HDL CHL ratio. …”
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A Truncated Multi-Thiol Aptamer-Based SARS-CoV-2 Electrochemical Biosensor: Towards Variant-Specific Point-of-Care Detection with Optimized Fabrication
Published 2025-01-01“…Thus, reducing fabrication time from 24 to 3 h and increasing the stability and sparseness for multi-thiol aptasensors compared to a standard aptasensor using single thiols, without a reduction in aptamer density. …”
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A Population Analysis of 20 Exoplanets Observed from Optical to Near-infrared Wavelengths with the Hubble Space Telescope: Evidence for Widespread Stellar Contamination
Published 2025-01-01“…To obtain spectral information from the near-ultraviolet to the near-infrared, we reanalyzed 16 WFC3 and over 50 STIS archival data sets with our dedicated HST pipeline. We also include 24 WFC3 data sets previously reduced with the same software. …”
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Trends in depressive symptoms among high school students with and without health-risk behaviors in the United States: A population-based studyResearch in context
Published 2025-02-01“…Depressive symptoms increased more among students engaging in ≤1 risk category (BAPC = 4.6% [3.6–5.7%]) than students engaging in 4–5 risk categories (BAPC = 2.9% [2.4–3.3%]) (interaction, p = 0.037) and there was a general trend toward decreasing engagement in risk behaviors among students with depressive symptoms. …”
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Hobbit: Providing Fall Detection and Prevention for the Elderly in the Real World
Published 2018-01-01Get full text
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311
Neural Correlates of Social Perception Deficit in Schizophrenia: An Event-related Potential Study
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Effects of entinostat, quisinostat, and tubastatin-A on alcohol consumption in male high ethanol consuming rats
Published 2025-02-01“…The objective of the current study was to test the effects of different HDACi on ethanol intake in two rat lines selectively bred for high ethanol-consumption.MethodAdult naïve male high alcohol drinking line 1 (HAD1) or alcohol-preferring (P) rats were given continuous 24-h, 3-bottle, free-choice access to 15%, 30% ethanol concurrently with water for 8 weeks prior to testing entinostat (selective HDAC1i and HADC3i, 0, 1.25, 2.5, 5 mg/kg, i. p.), quisinostat (pan HADCi, 0, 0.5, 1.0, 2.0 mg/kg, i. p.), or tubastatin-A (selective HDAC6i, 0, 1.25, 2.5, 5 mg/kg, i. p.) over 4-5 consecutive days.ResultsIn HAD1 rats, entinostat reduced 2-, 4-, and 24-h ethanol intake across the 2nd – 5th test days; while, in P rats, entinostat’s effect was primarily seen at the 24-h time-point, at the highest dose and only across three test days. …”
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Sustainable development model toward environmentally friendly hospital
Published 2023-11-01Get full text
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Keeping Active with Texting after Stroke (KATS): a single-arm feasibility and acceptability study of a behavioural intervention to promote community-based physical activity after s...
Published 2025-02-01“…Effect sizes (Cohen’s d; per cent change) were demonstrated in step count (0.2; 13%), extended activities of daily living (0.24; 8.3%) and mental well-being (0.35; 7%). Participants perceived KATS as acceptable, valuing messages and motivational prompts, but personalised tailoring was desired by some.Conclusions Recruitment, retention and outcome measure completion were feasible, and KATS was perceived as acceptable. …”
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Analysis of Risk Factors for Postoperative Progressive Segment Degeneration at the Decompression and Non-decompression Segments after Minimally Invasive Lumbar Decompression Surger...
Published 2025-01-01“…A logistic regression model identified that Cobb angle 10° (OR 2.53, 95% CI 1.50-4.24), spondylolisthesis 3 mm (OR 4.447, 95% CI 2.06-9.58), and level of segments were more likely to have PSD at the non-decompression level; additionally, lateral listhesis 3 mm (OR 2.91, 95% CI 1.08-7.81) was more likely to have PSD in the decompression segments. …”
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Insights Into Causal Effects of Genetically Proxied Lipids and Lipid‐Modifying Drug Targets on Cardiometabolic Diseases
Published 2025-02-01“…Moreover, significant Mendelian randomization and strong colocalization associations for the expression of LPL in blood and subcutaneous adipose tissue were linked with myocardial infarction (OR, 0.918 [95% CI, 0.872–0.967], P=1.24×10−3; PP.H4, 0.99) and coronary heart disease (OR, 0.991 [95% CI, 0.983–0.999], P=0.041; PP.H4=0.92). …”
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Triglyceride-glucose index: carotid intima-media thickness and cardiovascular risk in a European population
Published 2025-01-01“…Participants were generally non-obese, with an average BMI of 24.6 ± 3.5 Kg/m2. Among the women, 83.1% were postmenopausal. …”
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