Upadacitinib in active non-radiographic axial spondyloarthritis: 2-year data from the phase 3 SELECT-AXIS 2 study by Filip Van den Bosch, Atul Deodhar, Denis Poddubnyy, Walter P. Maksymowych, Désirée van der Heijde, Tae-Hwan Kim, Mitsumasa Kishimoto, Xenofon Baraliakos, Xianwei Bu, Ivan Lagunes-Galindo, In-Ho Song, Peter Wung, Koji Kato, Anna Shmagel

“…Abstract Background In SELECT-AXIS 2, upadacitinib improved the signs and symptoms of active non-radiographic axial spondyloarthritis (nr-axSpA) through 52 weeks versus placebo and was well tolerated. …”
Get full text

An Efficient and Practical Method for the Synthesis of Saxagliptin Intermediate 2-(3-Hydroxy-1-adamantane)-2-oxoacetic Acid and Its Optimization by Qi Liao, Lan Jiang, Cong Li, Yaling Shen, Min Wang, Chengkun Cao, Xiangnan Hu

“…A mild and relatively simple way for preparation of 2-(3-hydroxy-1-adamantane)-2-oxoacetic acid (I) was reported. …”
Get full text

Systematic Coronary Risk Evaluation 2 (SCORE2), arterial stiffness, and subclinical coronary atherosclerosis in a population-based study by Susanna Strömberg, Andreas Stomby, Jan Engvall, Carl Johan Östgren

“…Aim To investigate the association between Systematic Coronary Risk Evaluation 2 (SCORE2) and subclinical damage in two vascular beds: atherosclerosis in the coronary arteries and aortic arterial stiffness, in a large population-based cohort without cardiovascular disease or diabetes.Methods Design: A cross-sectional study based on Swedish CArdio Pulmonary bioImaging Study (SCAPIS) data. …”
Get full text

Optical and Electrical Properties of TiO2/Co/TiO2 Multilayer Films Grown by DC Magnetron Sputtering by Marcos G. Valluzzi, Lucas G. Valluzzi, Marcos Meyer, María A. Hernández-Fenollosa, Laura C. Damonte

“…Transparent oxide multilayer films of TiO2/Co/TiO2 were grown on glass substrate by DC magnetron sputtering technique. …”
Get full text

The crystal structure of 5,5′-diselanediyl-bis(2-hydroxybenzaldehyde), C14H10O4Se2 by Tingting Lin, Qiuling Peng, Meiyun Lv, Mengping Guo

“…C14H10O4Se2, triclinic, P1‾ $P\overline{1}$ (no. 2), a = 6.6836(11) Å, b = 8.9933(11) Å, c = 11.5062(19) Å, α = 77.128(12)°, β = 87.684(14)°, γ = 89.975(12)°, V = 673.65(18) Å3, Z = 2, R gt(F) = 0.0564, wR ref(F 2) = 0.1512, T = 293 K.…”
Get full text

Self-Care Practices and the Associated Socio-Demographic Variables of Persons with Type 2 Diabetes Mellitus (T2dm) in Southeast, Nigeria. by Okafor, Christiana Nkiru, Okonkwo, Uchenna Prosper, Ani, Kenneth Umezulike, Onuora, Ethel Ogoemeka, Nwokike, Mathew, Byabagambi, Jane Turyasingura, Tamu, JohnBosco Munezero, Mfitumukiza, Valence, Nwankwo, Mercy Chinenye, Tumusiime, Alex

Subjects: “…T2DM…”
Get full text

Self-Care Practices and the Associated Socio-Demographic Variables of Persons With Type 2 Diabetes Mellitus (T2dm) in Southeast, Nigeria. by Okafor, Christiana Nkiru, Okonkwo, Uchenna Prosper, Ani, Kenneth Umezulike, Onuora, Ethel Ogoemeka, Nwokike, Mathew, Turyasingura, Jane Byabagambi, Munezero, Tamu JohnBosco, Mfitumukiza1, Valence, Nwankwo, Mercy Chinenye, Tumusiime, Alex

Subjects: “…T2DM…”
Get full text

(E)-2-((E)-4-(2,6,6-trimethylcyclohex-1-en-1-yl)but-3-en-2-ylidene)hydrazine-1-carbothioamide C14H23N3S1 by Rong Zeng, Cong Huang, Yu-Fang Wu, Da-Yong Peng, Shang-Xing Chen

“…[C14H23N3S1], monoclinic, P21/c (no. 14), a = 15.1642(8) Å, b = 6.9215(3) Å, c = 15.2182(7) Å, β = 112.675(2)°, V = 1473.83(12) Å3, Z = 4, R gt(F) = 0.0453, wR ref(F 2) = 0.1240, T = 296(2) K.…”
Get full text

Comparative study on photocatalytic efficiency of Mg doped CuFeO2 versus TiO2 doped CuFeO2 delafossite based on their application for the removal of tartrazine yellow dye by Sayam Bhattacharyya, Sk Aakash Hossain, Sampad Sarkar, Papita Das

Subjects: “…CuFeO2 composite…”
Get full text

Crystal structure of (Z)-2-(1-bromo-2-phenylvinyl)-5-ethyl-2-methyl-1,3-dioxane-5-carboxylic acid, C15H17Br1O4 by Jia Guo-Kai, Yuan Xian-You

“…C15H17Br1O4, monoclinic, P21/n (no. 14), a = 7.1178(16) Å, b = 8.752(2) Å, c = 24.554(6) Å, β = 94.761(3)°, V = 1524.3(6) Å3, Z = 4, Rgt(F) = 0.0275, wRref(F2) = 0.0694, T = 296(2) K.…”
Get full text

Synthesis, crystal structure, Hirshfeld surface analysis and DFT calculations of the coordination compound tetraaquabis{2-[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]acetato-κO}cobalt(II) by Ekaterina Kinshakova, Batirbay Torambetov, Simranjeet Kaur, Jamshid Ashurov, Shakhnoza Kadirova

Subjects: Get full text

Sodium glucose co-transporter 2 (SGLT2) inhibitors versus dipeptidyl peptidase-4 (DPP-4) inhibitors and the risk of Atrial Fibrillation in patients with type 2 diabetes mellitus: a meta-analysis by Xiaoyan Liang, Jianghong Dai, Feifei Wang

Subjects: Get full text

Click Synthesis and Biologic Evaluation of ()- and ()-2-Amino-3-[1-(2-[F]Fluoroethyl)-1-[1,2,3]Triazol-4-yl]Propanoic Acid for Brain Tumor Imaging with Positron Emission Tomography by Jonathan McConathy, Dong Zhou, Stephany E. Shockley, Lynne A. Jones, Elizabeth A. Griffin, Hsiaoju Lee, Susan J. Adams, Robert H. Mach

“…The ( R )- and ( S )-enantiomers of 2-amino-3-[1-(2-[ 18 F]fluoroethyl)-1 H -[1,2,3]triazol-4-yl]propanoic acid (4) were synthesized and evaluated in the rat 9L gliosarcoma brain tumor model using cell uptake assays, biodistribution studies, and micro-positron emission tomography (microPET). …”
Get full text

Nucleosides 8 [18]: Ribosylation of Fused Quinazolines—Synthesis of New [1,2,4]Triazolo[5,1-b]- and [1,2,4]Triazino[3,2-b]quinazoline Nucleosides of Fluorescence Interest by Laila Mohamed Break, Mosselhi Abdelnabi Mosselhi, Nagi Mohamed Elshafai

“…[1,2,4]Triazolo[5,1-b]- and [1,2,4]triazino[3,2-b] quinazolines have been ribosylated by coupling with 1-O-acetyl-2,3,5-tri-O-benzoyl-β-D-ribofuranose and by using the silylation method, followed by debenzoylation by methanolic sodium methoxide to afford the corresponding free N-nucleosides. …”
Get full text

Crystal structure and Hirshfeld surface analysis of the chalcone derivative (2E)-3-[4-(diphenylamino)phenyl]-1-[4-(prop-1-yn-2-yloxy)phenyl]prop-2-en-1-one by Sundarasamy Madhan, M. NizamMohideen, Vijayan Viswanathan, Devadasan Velmurugan

“…In the crystal structure of the title chalcone derivative, C30H23NO2, the molecule adopts an s-cis conformation with respect to the C=O and C=C bonds. …”
Get full text

Evaluation of Anti-Cancer, Pro-Apoptotic, and Anti-Metastatic Effects of Synthetic Analogue Compound 2-Imino-7-Methoxy-4-(4-fluorophenyl)-2H-1,3-Thiazino [3,2-a] Benzimidazole on Pancreatic PaCa-2 and Melanoma A375 Cancer Cells by Mpho Ndou, Marthe C. D. Fotsing, Michael H. K. Kengne, Edwin M. Mmutlane, Derek T. Ndinteh, Mthokozisi B.C. Simelane, Lesetja Motadi, Mpho Choene

Subjects: Get full text

Crystal structure of di-μ-acetato-κ4O:O′-bis{(acetato-κ2O,O′)tetraaqua[1-(pyridin-2-ylmethylidene-κN)-2-(pyridin-2-yl-κN)hydrazine-κN1]lanthanum(III)} dinitrate hemihydrate by Mbossé Ndiaye-Gueye, Bocar Traoré, Ibrahima Elhadji Thiam, Ousmane Diouf, Emmanuel Wenger, Abdou Salam Sall, Claude Lecomte, Mohamed Gaye

Subjects: Get full text

Crystal structure of catena-poly[bis(μ2-azido-k2N:N′)-(nitrato-K2N:N′)-bis(1,10-phenanthroline-K2N:N′)samarium(III)], C24H16N11O3Sm by Feng Yu-Quan

“…C24H16N11O3Sm, monoclinic, P21/c (no. 14), a = 6.745(6) Å, b = 21.943(19) Å, c = 16.132(14) Å, β = 95.362(13)°, V = 2378(4) Å3, Z = 4, Rgt(F) = 0.0446, wRref(F2) = 0.1162, T = 296 K.…”
Get full text

Crystal structure of catena-poly[tetrakis(butyl)-μ2-2-((oxido(phenyl)methylene)hydrazineylidene)propanoato-κ4 O:O,O′,N-μ2-2-((oxido(phenyl)methylene)hydrazineylidene)propanoato-κ4 O,N,O′:N′-ditin(IV)], C34H50N6O6Sn2 by Gao Zhongjun, Zhang Haifeng

“…C34H50N6O6Sn2, triclinic, P 1‾ $\overline{1}$ , a = 12.110(2) Å, b = 12.406(2) Å, c = 13.744(3) Å, α = 79.547(2)° $79.547(2){}^{\circ}$ , β = 82.072(2)° $82.072(2){}^{\circ}$ , γ = 87.257(2)° $87.257(2){}^{\circ}$ , V = 2010.7(7) Å3, Z = 2, R gt(F) = 0.0471, wR ref(F 2) = 0.1392, T = 298 K.…”
Get full text

Brucea javanica oil inhibited the proliferation, migration, and invasion of oral squamous carcinoma by regulated the MTFR2 pathway by Yihan Lai, Yihan Lai, Mingkang Li, Mingkang Li, Juan Zhan, Juan Zhan, Lin Jiang, Lin Jiang, Yuan Wu, Zhiyi Fang, Jianhan Zhou, Jianhan Zhou, Yujie Ma, Yisen Shao, Yisen Shao, Wei Wang, Wei Wang

Subjects: Get full text