The MAPK MEK1/2-ERK1/2 Pathway and Its Implication in Hepatocyte Cell Cycle Control by Jean-Philippe Guégan, Christophe Frémin, Georges Baffet

“…In this paper, we will focus on MEK1/2-ERK1/2 activations and roles in normal rodent hepatocytes in vitro and in vivo after partial hepatectomy and in human hepatocarcinoma cells. …”
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Synthesis, Crystal Structure, and Spectra Properties of the Cadmium (II) Complex with Bis(N-allylbenzimidazol-2-ylmethyl)benzylamine by Huilu Wu, Jingkun Yuan, Ying Bai, Fan Kou, Fei Jia, Bin Liu

“…A novel complex of cadmium (II) picrate (pic) with V-shaped ligand bis(N-allylbenzimidazol-2-ylmethyl)benzylamine (babb), with composition [Cd(babb)2](pic)2, was synthesized and characterized by elemental analyses and electrical conductivity, IR, and UV/visible spectra. …”
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Natural killer cells occupy unique spatial neighborhoods in HER2- and HER2+ human breast cancers by Femke A. I. Ehlers, Katie E. Blise, Courtney B. Betts, Shamilene Sivagnanam, Loes F. S. Kooreman, E. Shelley Hwang, Gerard M. J. Bos, Lotte Wieten, Lisa M. Coussens

“…Owing to the clinical evidence supporting a significant role for NK cells in HER2+ breast cancer in mediating responses to Trastuzumab, we further evaluated HER2- and HER2+ specimens separately. …”
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Large anomalous transverse transport properties in atomically thin 2D Fe3GaTe2 by Brahim Marfoua, Jisang Hong

“…Motivated by the recent fabrication of two-dimensional (2D) ferromagnetic thin film Fe3GaTe2, we investigate the thickness-dependent anomalous transverse conductivities of the 2D Fe3GaTe2 system (from one to four layers). …”
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Reconciling the IPC and Two-Hit Models: Dissecting the Underlying Cellular and Molecular Mechanisms of Two Seemingly Opposing Frameworks by Carlos F. M. Morris, Muhammad Tahir, Samina Arshid, Mariana S. Castro, Wagner Fontes

“…This seemingly contradictory role that the two models attribute to a first inflammatory hit, as priming in the former and protective in the latter, has set these two theories on opposing corners of the literature. …”
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Electronic Structure and Room Temperature of 2D Dilute Magnetic Semiconductors in Bilayer MoS2-Doped Mn by Sintayehu Mekonnen Hailemariam

“…It is also found that two dopants in different layers of BL MoS2 communicate ferromagnetically. …”
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Association of Toll-Like Receptor 2 (TLR2) Expression in Placenta and Intrauterine Exposure to Hepatitis B Virus by Dian Utami, Maisuri T. Chalid, Rina Masadah, Rizalinda Sjahril, Andi Dwi Bahagia Febriani

“…Statistical analysis results showed that placental TLR2 expression did not indicate any association with hepatitis B virus DNA identified in cord blood with a p value of 0.730 and an OR of 0.650 (95% CI 0.173–2.440). …”
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The Molecular Effects of SGLT2i Empagliflozin on the Autophagy Pathway in Diabetes Mellitus Type 2 and Its Complications by Ranin Saad, Hagar Tadmor, Offir Ertracht, Nakhoul Nakhoul, Farid Nakhoul, Farber Evgeny, Shaul Atar

“…We aim to investigate the molecular effect of sodium-glucose transporter 2 inhibitor (SGLT2i) on the expression of ATG5 and its downstream collaborator LC3-II in diabetic nice model. …”
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Performance Analysis and Dimensional Optimization of 2RUP_aR-2RRU Parallel Mechanism by Linxian Che, Bing He, Jie Li, Haiyi Jiang

“…A novel plane symmetric 2RUP_aR-2RRU parallel mechanism with two translational and two rotational degrees of freedom is proposed， and it is can be used as the main body structure of a vibrating screen. …”
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Exome sequencing of UK birth cohorts [version 2; peer review: 2 approved, 1 approved with reservations] by Petr Danecek, Amy Hough, John Wright, Karen Ho, Nicholas J. Timpson, Sarah J. Lindsay, Davide Bonfanti, Daniel S. Malawsky, Rafaq Azad, Deborah Plowman, Sara Widaa, Gemma Shireby, Emla Fitzsimons, David Bann, Matthew E. Hurles, Hilary C. Martin, Susan M. Ring, Dan Mason, Michael A. Quail, Wei Huang, Vivek Iyer, Mahmoud Koko, Iaroslav Popov, Laurie Fabian, Gennadii Zakharov, Ruth Y. Eberhardt, Emma E. Wade, Qin Qin Huang

“…Here we present quality-controlled whole exome sequencing data from three UK birth cohorts: the Avon Longitudinal Study of Parents and Children (8,436 children and 3,215 parents), the Millenium Cohort Study (7,667 children and 6,925 parents) and Born in Bradford (8,784 children and 2,875 parents). The overall objective of this coordinated effort is to make the resulting high-quality data widely accessible to the global research community in a timely manner. …”
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A CO₂–Δ¹⁴CO₂ inversion setup for estimating European fossil CO₂ emissions by C. Gómez-Ortiz, G. Monteil, G. Monteil, S. Basu, S. Basu, M. Scholze

“…<p>Independent estimation and verification of fossil <span class="inline-formula">CO₂</span> emissions on a regional and national scale are crucial for evaluating the fossil <span class="inline-formula">CO₂</span> emissions and reductions reported by countries as part of their nationally determined contributions (NDCs). …”
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Silver Trimolybdate (Ag2Mo3O10.2H2O) Nanorods: Synthesis, Characterization, and Photo-Induced Antibacterial Activity under Visible-Light Irradiation by Maria Karollyna do Nascimento Silva Leandro, João Victor Barbosa Moura, Ana Carolina Justino de Araújo, Priscilla Ramos Freitas, Cicera Laura Roque Paulo, Amanda Karine de Sousa, Janaina Esmeraldo Rocha, Lívia Maria Garcia Leandro, Rakel Olinda Macedo da Silva, Clenilton Costa dos Santos, Jaime Ribeiro-Filho, Cleânio da Luz Lima, Abolghasem Siyadatpanah, Zahra Seifi, Bonglee Kim, Henrique Douglas Melo Coutinho

“…The present study reports the synthesis, characterization, and antibacterial properties of silver trimolybdate (Ag2Mo3O10.2H2O) nanorods. The synthesis was performed using a conventional hydrothermal method. …”
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Synthesis, Characterization, and Antibacterial Activities of 1H-Imidazo [5, 6-f] [1,10] Phenanthroline-2(3H)-Thione and Its Ni(II) and Cu(II) Complexes by Radiet Anbessie Tirkeso, Tilahun Wubalem Tsega, Gebru G/Tsadik Amdemichael

“…In line with this, 1H-imidazo [5, 6-f] [1,10] phenanthroline-2(3H)-thione and its complexes (Ni(II) and Cu(II)) were synthesized, characterized, and evaluated against bacterial strains. …”
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Crystal structure of (E)-7-hydroxy-2-((6-methoxypyridin-2-yl)methylene)-3,4-dihydronaphthalen-1(2H)-one, C17H15NO3 by Liang Lun-Hai, Zhao Feng-Lan, Meng Qing-Guo

“…C17H15NO3, triclinic, P1‾$P&#x203e;{1}$ (no. 2), a = 7.5016(4) Å, b = 13.6750(8) Å, c = 14.8557(9) Å, α = 115.469(6)°, β = 91.726(5)°, γ = 97.325(5)°, V = 1358.48(15) Å3, Z = 4, Rgt(F) = 0.0442, wRref(F2) = 0.1095, T = 100 K.…”
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Toll样受体4在乙型肝炎组织及细胞株HepG2/HepG2.2.15内的表达特征 by 郭云蔚, 尉秀清, 李永伟, 杨绍基

“…[目的]探讨Toll样受体4（TLR4）在乙型肝炎组织及细胞株HepG2/HepG2.2.15内的表达特征。[方法]采用免疫组化染色法检测慢性乙型病毒性肝炎（CHB）63例、慢性重型肝炎（CSH）11例及健康对照组10例肝组织TLR4的表达,综合评分法判断结果。…”
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Synthesis and Bioactivity of Some New 3-Alkyl-2,4-diisopropyl-1,2,4,5-tetrahydro-benzo[e][1,3,2]-diazaphosphepine 3-sulfides/selenides by Ch. Mohan, C. Naga Raju, A. Janardhan Rao

“…The synthetic route involves α,α′-dibromo-o-xylene (1) with two moles of isopropylamine (2) in the presence of triethylamine (TEA) in dry tetrahydrofuran (THF) at low temperature to form the compound 3. …”
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Design and Enantiopure Synthesis of(R)-2-((2-Oxooxazolidin-5-yl)methyl)isoindoline-1,3-dione: A Key Precursor to Build 2-Oxazolidinone Class of Antibacterial Agents by T. Rajesh, P. Suryanarayana Reddy, M. Manidhar, M. Vijaya Lakshmi, G. Madhusudhan

“…One among the two proposed approaches, is succeeded in preparing enantiopure targeted chiral building block using (R)-2-(chloromethyl)oxirane ((R)-epichlorohydrin) as precursor. …”
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The crystal structure of 1,2-bis(pyridinium-4-yl)ethane diperchlorate, C12H14N2·2ClO4 – a second polymorph by Qiu Qi-Ming, Song Jian-Biao, Yan Li, Dong Ai-Guo, Li Chuan-Tao, Zheng Zhi-Yuan

“…C12H14N2·2ClO4, monoclinic, P21/c (no. 14), a = 5.3170(4) Å, b = 12.8711(8) Å, c = 11.6788(7) Å, β = 100.888(2)°, V = 784.86(9) Å3, Z = 2, Rgt(F) = 0.0434, wRref(F2) = 0.1211, T = 298 K.…”
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Theoretical Study of CO, NO, NO₂, Cl₂, and H₂S Adsorption Interactions with PdO–Graphene Composites for Gas Sensor Applications by Piumantha Samaranayake, Azeez Ahamed, Visal de Silva, Nadeesha Manohari Wickramage, Muhammad Raziq Rahimi Kooh, Roshan Thotagamuge

“…NO₂ demonstrated the highest sensitivity, at 1285.2% for the PdO–graphene composite, and the lowest were Cl₂ and H₂S, with a sensitivity of 99.9%, while Cl₂ had the shortest recovery time of 7.66 × 10⁻¹¹ s, and CO had the longest recovery time of 2.55 × 10⁻¹⁰ s. …”
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Crystal structure and Hirshfeld surface analysis of supramolecular aggregate of 2,2,6,6-tetramethylpiperidin-1-ium bromide with 1,2,3,4-tetrafluoro-5,6-diiodobenzene by Atash V. Gurbanov, Tuncer Hökelek, Gunay Z. Mammadova, Khudayar I. Hasanov, Tahir A. Javadzade, Alebel N. Belay

“…The asymmetric unit of the title compound, C9H20N+·Br−·C6F4I2, contains one 2,2,6,6 tetramethylpiperidine-1-ium cation, one 1,2,3,4-tetrafluoro-5,6-diiodobenzene molecule, and one uncoordinated bromide anion. …”
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