Determinación del polimorfismo pro12ala en el receptor activado por proliferadores de peroxisomas gamma-2 en pacientes que padecen diabetes mellitus tipo 2 by Evelyn Visuete, Tomás A. Diez, Edgardo Castro, Magaly de Chial, Ana E. Tejada, Carlos W. Ramos D.

Subjects: “…PPARγ2…”
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Synthesis, crystal structure and Hirshfeld surface analysis of 5-oxo-N-phenyl-3-(thiophen-2-yl)-2,3,4,5-tetrahydro-[1,1′-biphenyl]-4-carboxamide by Khatira N. Aliyeva, Tuncer Hökelek, Victor N. Khrustalev, Rovnag M. Rzayev, Ajaya Bhattarai, Abel M. Maharramov, Namig G. Shikhaliyev

“…The asymmetric unit of the title compound, C23H19NO2S, contains two molecules that differ in the conformation of the two carboxamide moieties. …”
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Impact of pathogenic mutations of the GLUT1 glucose transporter on solute carrier dynamics using ComDYN enhanced sampling [version 2; peer review: 2 approved, 1 approved with reservations] by K. Anton Feenstra, Akiko Higuchi, Kei Yura, Sanne Abeln, Halima Mouhib

“…Several pathogenic mutations are reported in the glucose transporter subfamily SLC2, causing Glut1-deficiency syndrome (GLUT1DS1, GLUT1DS2), epilepsy (EIG2) and cryohydrocytosis with neurological defects (Dystonia-9). …”
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MEK1/2 Inhibitor (GDC0623) Promotes Osteogenic Differentiation of Primary Osteoblasts Inhibited by IL-1β through the MEK-Erk1/2 and Jak/Stat3 Pathways by Zeng-Qiao Zhang, Xiao-Shen Hu, Ye-Chen Lu, Jun-Peng Zhang, Wen-Yao Li, Wei-Yang Zhang, Wei Feng, Dao-Fang Ding, Jian-Guang Xu

“…However, blocking of the MEK-Erk1/2 signaling pathway by GDC0623 treatment reversed these effects. …”
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Experiences of the International In-Training Examination (I-ITE) by Rwandan pediatric residents – a survey-study describing candidate feedback [version 2; peer review: 1 approved, 2 approved with reservations] by Christian Umuhoza, Natalie McCall, Peter Thomas Cartledge

“…Five themes emerged from the qualitative analysis; 1) undertaking the I-ITE was a positive experience; 2) exam content; 3) formative nature of the assessment; 4) challenges to completing the exam; 5) practicalities to undertaking the exam. …”
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Prevalence, aetiology, and service mapping of dementia in rural Uganda. Part of DEPEND Uganda (Dementia Epidemiology, unmet Need and co-Developing Solutions in Uganda). [version 2; peer review: 2 approved] by Joseph Mugisha, Nicholas J Ashton, Claire J Steves, Racheal Alinaitwe, Josephine Prynn, Tunde Peto, Beatrice Kimono, Martin Prince

“…In Part 1, cohort participants are selected based on screening scores to undergo detailed cognitive assessment, using methods developed by the 10/66 Dementia Research Group. Part 2 is a case control study of people with and without dementia using antecedent data, questionnaires, physical assessment, retinal imaging, and Alzheimer’s blood-based biomarkers. …”
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A prospective, randomized, single-center, two-arm, open-label study to evaluate the efficacy of biotherapi®, a two-strain bacillus probiotic blend, as an adjunctive therapy in the treatment of rheumatoid arthritis by Arindam Nandy Roy, Yarram Ashok Kumar, Syeda Sana Fatima

“…Methods: In this prospective, randomized, single-center, two-arm, open-label study, patients were randomized (1:1) to receive twice-daily adjunctive Biotherapi® (n = 125) or standard of care alone (n = 125) for 12 weeks. …”
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Technology development, application and prospect of cellular vehicle-to-everything (C-V2X) by Shanzhi CHEN, Yuming GE, Yan SHI

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Narrow band based and broadband derived vegetation indices using Sentinel-2 Imagery to estimate vegetation biomass by A.B. Imran, K. Khan, N. Ali, N. Ahmad, A. Ali, K. Shah

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Designing a glass nanoshell on barium titanium trioxide to suppress nanocrystal growth during sintering for fine-grain dielectric ceramics by Jia Yu, Qi Jiang, Qingchao Jia, Liangzhu Zhang, Wenchun Chiu, Huidan Zeng

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Sulforaphane enhances Nrf2-mediated antioxidant responses of skeletal muscle induced by exhaustive exercise in HIIT mice by Yangwenjie Wang, Yang Xiang, Ruiqi Wang, Xiangning Li, Jianxiong Wang, Siwang Yu, Ying Zhang

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Assessment of Air Pollution and Lagged Meteorological Effects in an Urban Residential Area of Kenitra City, Morocco by Mustapha Zghaid, Abdelfettah Benchrif, Mounia Tahri, Amine Arfaoui, Malika Elouardi, Mohamed Derdaki, Ali Quyou, Moulay Laarbi Ouahidi

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Synthesis of thiophene and N-substituted thieno[3,2-d] pyrimidine derivatives as potent antitumor and antibacterial agents by Hafez Hend N., Alsalamah Sulaiman A., El-Gazzar Abdel-Rhman B. A.

Subjects: “…thieno[3,2-d]pyrimidines…”
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Lactobacillus plantarum J26 alleviates alcohol-induced oxidative liver injury by regulating the Nrf2 signaling pathway by Hongxuan Li, Shasha Cheng, Yuhong Wang, Yilin Sun, Jiaxin Zhang, Mingshuang Sun, Chaoxin Man, Yu Zhang, Yujun Jiang

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The mediating role of English learning motivation between socioeconomic status and pragmatic awareness by Xiaomeng Hui, Yuqing Chen

Subjects: “…L2 motivational self-system (L2MSS)…”
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Crystal structure of dibromido-(1-methyl-1H-imidazole-κ1N)-(3-(3-methyl-1H-imidazol-3-ium-1-yl)propanoato-κ1O)zinc(II), C11H16Br2N4O2Zn by Liu Pengju, Wang Zongwei, Guo Libing, Tang Junming

“…C11H16Br2N4O2Zn, monoclinic, Cc (no. 9), a = 15.534(7) Å, b = 7.956(4) Å, c = 14.589(7) Å, β = 119.094(8)°, V = 1575.5(13) Å3, Z = 4, Rgt(F) = 0.0296, wRref(F2) = 0.0703, T = 296 K.…”
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江苏盐城首次记录到彩鹮 by 刘 彬 1, 2 薛丹丹 2 安玉亭 2 王立波 2 孙大明 2 杨禹治 2 鲁长虎 1

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动物季节性迁徙研究进展 by 徐晶 1, 2 徐鸿洋 1, 2 刘春霞 1, 2 张焱如 1, 2 曹俊伟 1, 2 周欢敏 1, 2

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α-细辛醚对秦岭滑蜥断尾后芽基形成时期细胞增殖的影响 by 赵禹 1, 2, 李琳 2, 寇曌婷 2, 高燕燕 2, 邵晓忠 1, 杨纯 1, 2

“…结果显示：PCNA在不同实验分组和不同阶段尾组织中均有表达，在空白组18 d的脊髓中表达最弱，灰度值为188.09±1.98，而实验组20 d的脊髓中表达最强，灰度值为123.10±2.91。实验组的再生尾皮肤组织、肌肉组织和脊髓中PCNA的表达强度均高于空白组和对照组，且对照组与实验组的脊髓中的表达强度具有显著差异（P<0.05）。…”
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应用Illumina MiSeq测序技术对腹泻北平顶猴肠道菌群的分析 by 金洁 1, 2 张飞燕 1, 2 张庆宇 1, 2 王芸 1, 2 吕龙宝 1, 2

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