Targeting the NOTCH2/ADAM10/TCF7L2 Axis‐Mediated Transcriptional Regulation of Wnt Pathway Suppresses Tumor Growth and Enhances Chemosensitivity in Colorectal Cancer by Zhen Xiang, Yiwei Wang, Xiao Ma, Shuzheng Song, Yuanqiao He, Jiamin Zhou, Longhai Feng, Su Yang, Yibin Wu, Bingran Yu, Guangkai Xia, Weiqi Xu, Yiming Zhao, Lu Wang

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Bone marrow mesenchymal stem cell‐derived exosomes improve renal fibrosis by reducing the polarisation of M1 and M2 macrophages through the activation of EP2 receptors by Yuqing Lu, Lulu Yang, Xiao Chen, Jing Liu, Anqi Nie, Xiaolan Chen

Subjects: “…EP2…”
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Fabrication of self-standing hyperbranched poly(ethyleneimine) film with shape-memory and copper adsorption behavior via simple polymer reaction with tetraazacalix[2]arene[2]triazine dichloride by Tomohiro Suzuki, Ryota Shibata, Tadashi Tsukamoto, Yuji Shibasaki

“…Hyperbranched poly(ethyleneimine) (PEI, Mn 10 kDa) was simply reacted with tetraazacalix[2]arene[2]triazine (ACAT) dichloride in a feed ratio from 1:1 to 1:5 under diluted conditions to produce self-standing PEI modified films with good mechanical strength and thermal properties. …”
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HER2-related biomarkers predict clinical outcomes with trastuzumab deruxtecan treatment in patients with HER2-expressing metastatic colorectal cancer: biomarker analyses of DESTINY-CRC01 by Salvatore Siena, Kanwal Raghav, Toshiki Masuishi, Kensei Yamaguchi, Tomohiro Nishina, Elena Elez, Javier Rodriguez, Ian Chau, Maria Di Bartolomeo, Hisato Kawakami, Fumitaka Suto, Makito Koga, Koichiro Inaki, Yusuke Kuwahara, Issey Takehara, Daniel Barrios, Kojiro Kobayashi, Axel Grothey, Takayuki Yoshino

“…Abstract DESTINY-CRC01 (NCT03384940) was a multicentre, open-label, phase 2 study that investigated the safety and efficacy of trastuzumab deruxtecan (T-DXd) in patients with human epidermal growth factor receptor 2 (HER2)-expressing metastatic colorectal cancer (CRC). …”
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T3P- A Novel Catalyst for Aza-Diels-Alder Reaction: One-Pot Synthesis of Pyrano[3,2-c]quinolines and furano[3,2-c]quinolines by T. S. R. Prasanna, K. Mohana Raju

“…T3P was found to be an efficient catalyst for the Aza-Diels–Alder reactions of aldimines with dihydropyran or dihydrofuran to afford the corresponding pyrano-and furo [3,2-c]quinolines in high yields with high diastereoselectivity in a short period of time.…”
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Multi-method evaluation of a 2-(1,3,4-thiadiazole-2-yl)pyrrolidine corrosion inhibitor for mild steel in HCl: combining gravimetric, electrochemical, and DFT approaches by Ahmed Al-Amiery, Wan Nor Roslam Wan Isahak, Waleed Khalid Al-Azzawi

“…Abstract The corrosion inhibition properties of 2-(1,3,4-thiadiazole-2-yl)pyrrolidine (2-TP) on mild steel in a 1 M HCl solution were investigated using weight loss, potentiodynamic polarization, electrochemical impedance spectroscopy (EIS) and open circuit potential (OCP) measurements. …”
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How science and policy came together and made a global impact: The EU common list of COVID-19 antigen tests [version 2; peer review: 2 approved] by Maddalena Querci, Barbara Raffael, Gabriele Leoni, Mauro Petrillo, Tobias Wiesenthal, Yoline Kuipers

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Phytotoxic Activity Analysis of 2-Methoxyphenol and 2,6-Di-<i>tert</i>-butyl-4-methylphenol Present in <i>Cistus ladanifer</i> L. Essential Oil by Diego Orellana Dávila, David F. Frazão, Amélia M. Silva, Teresa Sosa Díaz

“…The evaluation of the wide variety of allelochemicals present in allelopathic plants allows the detection of safer bioherbicides with new mechanisms of action. This study tested two phenolic compounds of <i>Cistus ladanifer</i> essential oil (2-Methoxyphenol and 2,6-Di-<i>tert</i>-butyl-4-methylphenol), which are commercially available. …”
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Study of Complexation Patterns in the System Ni2+, MoO42–, P2O74–, Cit3–for the Development of Poly-Ligand Electrolytes (Study of complexation patterns) by T. Nenastina, M. Sakhnenko, S. Oksak, G. Yar-Mukhamedova, D. Zellele, G. Mussabek, A. Imanbayeva

“… The complexation behavior in systems containing Ni2+, MoO42−, P2O74−, Cit3− - ions have been thoroughly investigated. …”
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Enhanced renoprotective effects of combined glucagon‐like peptide‐1 receptor agonists and sodium‐glucose cotransporter 2 inhibitors in type 2 diabetes mellitus: Real‐world evidence by Jian‐Yu Jhu, Yu‐Wei Fang, Chung‐Yen Huang, Hung‐Hsiang Liou, Mon‐Ting Chen, Ming‐Hsien Tsai

Subjects: “…Sodium–glucose cotransporter 2 inhibitors…”
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B3LYP Study on Reduction Mechanisms from O2 to H2O at the Catalytic Sites of Fully Reduced and Mixed-Valence Bovine Cytochrome 𝑐 Oxidases by Yasunori Yoshioka, Masaki Mitani

“…The MV C𝑐O catalyses reduction to produce one water molecule, while the FR C𝑐O catalyses to produce two water molecules. One water molecule is added into vacant space between His240 and His290 in the catalytic site. …”
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Enhanced Electrochemical Performance of γ-Fe2O3/Cr2O3/Graphene Oxide/Sodium Alginate Hybrid Nanocomposite Aerogels for High-Efficiency Ultracapacitors by Rasha Shakir Mahmood, Dhia Hadi Hussain

“…These impressive results belong to the excellent surface area of the γ-Fe2O3/Cr2O3/GO/SA hybrid aerogel, provided by adding two types of semiconductors (γ-Fe2O3 and Cr2O3), which reduces the graphene oxide sheets agglomeration. …”
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Interaction between Angiotensin II and Insulin/IGF-1 Exerted a Synergistic Stimulatory Effect on ERK1/2 Activation in Adrenocortical Carcinoma H295R Cells by An-li Tong, Fen Wang, Yun-ying Cui, Chun-yan Li, Yu-xiu Li

“…Compared to the control, 100 nM Ang II increased phospho-ERK1/2 approximately 3-fold. …”
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Antimony recovery from recycled terminals of lead-acid batteries with Na2CO3 and SiC after firstly SsB2O3 formation by Jiménez-Lugos J.C., Sánchez-Alvarado R.G., Cruz-Ramírez A., Romero-Serrano J.A., Hernández-Ramírez A., Rivera-Salinas J.E.

“…Terminals obtained from spent lead-acid batteries in Mexico contain around 2 wt% Sb. The terminals were melted in an electric furnace and then oxygen was injected at 750 °C with a gas flow rate of 2 L/min to produce high purity Sb2O3. …”
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Exploring Breastfeeding Mothers’ and Lactation Consultants’ Experiences of Lactation Consultancy Throughout the Restrictions Put in Place Due to the COVID-19 Pandemic [version 2; peer review: 2 approved] by Anne Matthews, Anna Connolly

“…Results Five key themes were identified: ‘Lack of Support’, ‘Adapting to COVID-19 Restrictions’, Emotional Response to COVID-19 and Restrictions’, Vaccination against SARS-CoV-2 as a Barrier to and Facilitator of Support’ and Inconsistency of Lactation Support Across Ireland’. …”
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Quasinormal modes of three $$(2+1)$$ ( 2 + 1 ) -dimensional black holes in string theory, conformal gravity, and Hu–Sawicki F(R) theory via the Heun function by F. Naderi, A. Rezaei-Aghdam

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Electrochemical behavior of lanthanum and yttrium ions in two molten chlorides with different oxoacidic properties: The eutectic LiCl-KCl and the equimolar mixture CaCl2-NaCl by Castrillejo Y., Bermejo M.R., Martínez A.M., Díaz Arocas P.

“…The electrochemical behavior of LaCl3 and YCl3 was studied in two molten chloride mixtures with different oxoacidic properties, the eutectic LiCl-KCl and the equimolar CaCl2-NaCl melt at different temperatures. …”
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CYP2C19 polymorphism and coronary in-stent restenosis: A systematic review and meta-analysis [version 3; peer review: 2 approved, 1 approved with reservations] by Ivana Purnama Dewi, Irawan Yusuf, Agussalim Bukhari, Muzakkir Amir, Vitriyaturrida ., Yusra Pintaningrum, Idar Mappangara, Hendy Bhaskara Perdana Putra

Subjects: “…CYP2C19…”
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Deep Learning Unravels Differences Between Kinematic and Kinetic Gait Cycle Time Series from Two Control Samples of Healthy Children Assessed in Two Different Gait Laboratories by Alfonso de Gorostegui, Damien Kiernan, Juan-Andrés Martín-Gonzalo, Javier López-López, Irene Pulido-Valdeolivas, Estrella Rausell, Massimiliano Zanin, David Gómez-Andrés

“…We investigate the application of deep learning in comparing gait cycle time series from two groups of healthy children, each assessed in different gait laboratories. …”
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The crystal structure of dimethyl 2,2ʹ-((adamantane-1,3-diylbis(4,1-phenylene)) bis(oxy))diacetate, C28H32O6 by Chen Xiao-Ming, Zeng Fei

“…C28H32O6, orthorhombic, Pnma (no. 62), a = 7.752(2) Å, b = 29.959(8) Å, c = 10.176(3) Å, V = 2363.5(11) Å3, Z = 4, R gt(F) = 0.1145, wR ref(F 2) = 0.1076, T = 296(2) K.…”
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