Donafenib combined with sintilimab for advanced hepatocellular carcinoma: a single arm phase II trial by Xiaoyang Hong, Yongjian Guo, Wenbo Shi, Kangshun Zhu, Licong Liang, Liteng Lin, Ye Chen, Jingwen Zhou, Jingjun Huang, Jiabai Huang, Yaozhu Wu, Wensou Huang, Mingyue Cai

“…Trial registration ClinicalTrials.gov (identifier: NCT05162352; date of registration: December 4, 2021).…”
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Adverse events of hepatic anti-fibrotic agents in phase 3 and above clinical trials: a descriptive analysis of the WHO-VigiAccess database by Yuwei Liu, Yuwei Liu, Xu Zhao, Xu Zhao, Xinrui Wang, Xinrui Wang, Qiang Zhou, Qiang Zhou

“…This study assessed ADRs associated with anti-fibrotic agents as reported in the World Health Organization (WHO) VigiAccess database and compared the adverse reaction characteristics of these agents for optimizing therapeutic strategies.MethodsA detailed search was conducted on ClinicalTrial.gov to identify phase 3 or 4 clinical trials involving hepatic anti-fibrotic agents. …”
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A randomized controlled, trial on effects of mobile phone text messaging in combination with motivational interviewing versus standard infant feeding counselling on breastfeeding a... by Moleen Zunza, Lehana Thabane, Louise Kuhn, Christine Els, Carl Lombard, Mark F. Cotton, Taryn Young

“…Trial registration The trial was registered on ClinicalTrials.gov (NCT05063240) and Pan African Clinical Trial Registries (PACTR202110870407786) before recruitment of the first subject.…”
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Vagal Blocking Improves Glycemic Control and Elevated Blood Pressure in Obese Subjects with Type 2 Diabetes Mellitus by S. Shikora, J. Toouli, M. F. Herrera, B. Kulseng, H. Zulewski, R. Brancatisano, L. Kow, J. P. Pantoja, G. Johnsen, A. Brancatisano, K. S. Tweden, M. B. Knudson, C. J. Billington

“…This trial is registered with ClinicalTrials.gov NCT00555958.…”
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SNP-array profiling data from breast cancer patients and healthy women's blood DNA samplesGEO by Rafika Indah Paramita, Sonar Soni Panigoro, Fadilah Fadilah, Septelia Inawati Wanandi, Noorwati Sutandyo

“…The idat raw data files have been added to the Gene Expression Omnibus (GEO) with accession number: GSE245794 (https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE245794).…”
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Can home care work be organized to promote musculoskeletal health for workers? Results from the GoldiCare cluster randomized controlled trial by Fredrik Klæboe Lohne, Marius Steiro Fimland, Javier Palarea-Albaladejo, Svend Erik Mathiassen, Andreas Holtermann, Skender Redzovic

“…Trial registration Clinicaltrials.gov ID: NCT05487027, submitted: 03/08/2022.…”
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Peripheral neuropathy in the phase 3 ASPEN study of Bruton tyrosine kinase inhibitors for Waldenström macroglobulinemia by Benjamin M. Heyman, Stephen S. Opat, Björn E. Wahlin, Meletios-Athanasios C. Dimopoulos, Jorge J. Castillo, Alessandra Tedeschi, Constantine S. Tam, Christian Buske, Roger G. Owen, Véronique Leblond, Judith Trotman, Gisoo Barnes, Wai Y. Chan, Jingjing Schneider, Heather Allewelt, Aileen Cohen, Jeffrey V. Matous

“…This trial was registered at www.clinicaltrials.gov as #NCT03053440.…”
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Almond snacking modestly improves diet quality and waist circumference but not psychosocial assessments and other cardiometabolic markers in overweight, middle-aged adults: A rando... by Vernon Uganiza Rayo, Lauren Okamoto, Maricarmen Cervantes, Mee Young Hong, Nathaniel Jason, Mark Kern, Changqi Liu, Elise North, Svitlana Storm, Oliver C. Witard, Shirin Hooshmand

“…Future mechanistic studies are warranted to understand the effect of almond supplementation on cardiometabolic health in various populations. ClinicalTrials.gov Identifier: NCT04787718.…”
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Fetal cardiac function in pregnancy affected by congenital heart disease: protocol for a multicentre prospective cohort study by Anna Erenbourg, Tracie Barber, Vera Cecotti, Stefano Faiola, Ilaria Fantasia, Tamara Stampaljia, Hagai Avnet, Beata Radzymińska-Chruściel, Neama Meriki, Alec Welsh

“…Trial registration The study protocol has been registered in the ClinicalTrials.gov Protocol Registration System, identification number NCT05698277.…”
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Diagnosing and managing patients with heart failure with preserved ejection fraction: a consensus survey by Christi Deaton, Robin Fox, Ian Wellwood, Carolyn Chew-Graham, Katherine Brown, Sharon Dixon, Thomas Blakeman, Alistair Brown, Julie Smith, Nick Thomas, Adam Jones, Basilio Hernandez-Diaz, Christopher Keast, Heather Rutter, Kyle Knox, Matthew Gaw, Nick Wooding, Christine A'Court, Hannah Swayze, Helen Ashdown, Victoria Glover, Rosalynn Austin, Eva Khair, Muhammad Zakir Hossain, Emma Sowden, Faye Forsyth, Mollika Chakravorty, Sophie Maclachlan, Edward Kane, Jessica Odone, Natasha Thorley, Susana Borja-Boluda, Muhammed Hossain, John Sharpley, Brain Gordon, Joanna Taffe, Aaron Long, Affan Aziz, Chris Schramm, Sine MacDonald, Helena Papworth, Craig Needs, David Cronk, Chris Newark, Duncan Blake, Amman Basuita, Emma Gayton, Jonathan Crawshaw, Rachael Ayerst, Shamila Wanninayake, Elisabetta Angeleri-Rand

“…Creation of collaborative care pathways is needed to support the increasing number of older patients with HFpEF.Trial registration number ClinicalTrials. gov (reference number: NCT03617848).…”
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The prolonged health sequelae “of the COVID-19 pandemic” in sub-Saharan Africa: a systematic review and meta-analysis by Melsew Setegn Alie, Getayeneh Antehunegn Tesema, Getayeneh Antehunegn Tesema, Gossa Fetene Abebe, Desalegn Girma

“…It is crucial for individuals who have recovered from COVID-19 to receive careful follow-up care to assess and reduce any potential organ damage and maintain their quality of life.Systematic review registrationClinicaltrial.gov, identifier CRD42024501158.…”
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Efficacy and Safety of Aprocitentan in the Treatment of Hypertension: A Meta-Analysis of Evidence from Randomized Controlled Trials by Li Zheng, Ming Liu, Xiaotong Gu, Yatong Zhang, Yan Wang

“…Methods: We searched PubMed, Embase, ClinicalTrials.gov, and the Cochrane Library databases from inception to June 3, 2024, for randomized controlled trials (RCTs) that compared the efficacy and safety between aprocitentan and placebo in treating hypertension. …”
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Myofascial trigger points therapy increases neck mobility and reduces headache pain in migraine patients – pilot study by Maciej Olesiejuk, Małgorzata Chalimoniuk, Tomasz Sacewicz

“…Trial registration The study protocol was retrospectively registered on December 2, 2022, as a clinical trial in the international clinical trial database ClinicalTrials.gov (identifier: NCT05646160). Clinical trial number: not applicable.…”
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Proportional Assist Ventilation for Minimizing the Duration of Mechanical Ventilation (the PROMIZING study): update to the statistical analysis plan for a randomized controlled tri... by Karen J. Bosma, Myriam Lafreniere-Roula, Arlene Jiang, Anna Heath, Yongdong Ouyang, Kaitlyn Wade, Pingzhao Hu, Karen E. A. Burns, Claudio M. Martin, Yoanna Skrobik, Sorcha Mulligan, Kevin E. Thorpe, Laurent Brochard, members of the Canadian Critical Care Trials Group and the REVA Network

“…Trial registration ClinicalTrials.gov Identifier: NCT02447692 prospectively registered May 19, 2015.…”
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Developing and testing the feasibility of a theory-based brief counseling intervention to promote physical activity in breast cancer survivors enrolled in the PAC-WOMAN trial by Sofia Franco, Eliana V. Carraça, Inês Nobre, Bruno Rodrigues, Vítor Ilharco, Lea Kahlert, Marlene N. Silva

“…Trial registration NCT05860621, registered 20 April 2023 — retrospectively registered, https://clinicaltrials.gov/study/NCT05860621 . Registered 21 April 2023 — retrospectively registered, https://doi.org/10.17605/OSF.IO/ZAQ9N . …”
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Phase II study with sorafenib plus radiotherapy for advanced HCC with portal and/or hepatic vein tumor thrombosis by Yirui Zhai, Liming Wang, Hong Zhao, Fan Wu, Lingxia Xin, Feng Ye, Wei Sun, Yan Song, Lijuan Niu, Huiying Zeng, Jingbo Wang, Yuan Tang, Yongwen Song, Yueping Liu, Hui Fang, Ningning Lu, Hao Jing, Shunan Qi, Wenwen Zhang, Shulian Wang, Ye-Xiong Li, Jianxiong Wu, Bo Chen

“…Clinical trials registration: This study is registered at ClinicalTrials.gov (NCT03535259).…”
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The analgesic effectiveness of auriculotherapy for acute postoperative pain: A systematic review and meta-analysis by Guilin Zhang, Guixing Xu, Yao Tang, Lingxue Zhang, Xi Chen, Xingyu Liang, Ling Zhao, Dehua Li

“…Methods: We searched the MEDLINE, Web of Science, Embase, Cochrane Library, CINAHL Complete, and ClinicalTrials.gov from inception to January 23, 2024 for all randomized controlled trials (RCTs) of auriculotherapy in the treatment of APP. …”
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CHAT-S study protocol: A randomized controlled trial of a health insurance literacy education program for young adult cancer survivors by Mary Killela, Cindy A. Turner, Amy Chevrier, Monique Stefanou, Perla L. Vaca Lopez, Heydon K. Kaddas, Karely M. van Thiel Berghuijs, Echo L. Warner, Giselle K. Perez, Austin R. Waters, Douglas B. Fair, Richard E. Nelson, Mark A. Lewis, Elyse R. Park, Anne C. Kirchhoff

“…We will also conduct cost-effectiveness and budget impact analyses.Discussion: Anticipated results from this trial could identify key information that YA cancer survivors need to improve health insurance literacy and survivorship care.Trial registration: ClinicalTrials.gov identifier: NCT05829070. Registered on April 25, 2023.…”
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Absence of Standard Modifiable Risk Factors in Middle Eastern Patients with Atherosclerotic Cardiovascular Disease. The Jordan Absence of Standard Modifiable Risk Factors (SMuRF-Le... by Hammoudeh AJ, Aldalal’ah M, Smadi EA, Alrishoud D, Alomari A, Alkhawaldeh M, Rizik A, Okour MF, Araydah M

“…SMuRF-less patients were younger, had less comorbid disease, received less secondary prevention pharmacotherapy and had higher rate of one year mortality than those with SMuRFs.Clinical Trials: The study is registered with ClinicalTrials.gov, unique identifier number NCT06199869.Keywords: atherosclerotic cardiovascular disease, standard modifiable risk factors, SMuRF-less patients, Middle Eastern patients…”
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Prior Anticoagulation and Risk of Hemorrhagic Transformation in Acute Stroke: A Post Hoc Analysis of the PRODAST Study by Gerrit M. Grosse, Anika Hüsing, Andreas Stang, Nils Kuklik, Marcus Brinkmann, Martin Grond, Jens D. Rollnik, Lars Marquardt, Andrea Kraft, Eckhard Schlemm, Carsten Eggers, Christoph C. Eschenfelder, Christian Weimar, Hans‐Christoph Diener

“…Registration URL: https://www.clinicaltrials.gov; Unique identifier: NCT02507856.…”
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