Prognostic factors for outcomes of idiopathic sudden sensorineural hearing loss: protocol for the SeaSHeL national prospective cohort study by Helen Blackshaw, Anne GM Schilder, Rishi Mandavia, Gerjon Hannink, Muhammad Nayeem Ahmed, Yaami Premakumar, Timothy Shun Man Chu, Tanjinah Ferdous, Nishchay Mehta, Joseph Manjaly, Maha Khan

“…Publication will be on behalf of study sites and collaborators.Trial registration number ClinicalTrials.gov Registry (NCT04108598).…”
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A Live Video Resiliency Dyadic Intervention for Persons With Dementia and Their Care-Partners Early After Diagnosis: Protocol for Open Pilot of Resilient Together for Dementia by Sydney McCage, Kristin Walker, Talea Cornelius, Robert A Parker, Kristen Dams-O'Connor, Brad Dickerson, Christine Ritchie, Ana-Maria Vranceanu, Sarah Bannon

“…ResultsThis study has been approved by the MSH institutional review board and is registered on ClinicalTrials.gov (NCT06421545). We anticipate that the study will be completed by late 2024. …”
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evoke and evoke+: design of two large-scale, double-blind, placebo-controlled, phase 3 studies evaluating efficacy, safety, and tolerability of semaglutide in early-stage symptomat... by Jeffrey L. Cummings, Alireza Atri, Howard H. Feldman, Oskar Hansson, Mary Sano, Filip K. Knop, Peter Johannsen, Teresa León, Philip Scheltens

“…Trial registration Clinicaltrials.gov, NCT04777396 and NCT04777409. Date: 02/03/2021…”
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Device endothelialization and morphology assessments at 1 year using computed tomography angiography: comparison of traditional with novel puncturable atrial septal defect occluder... by Yanxing Fang, Kai Hou, Dawei Lin, Daxin Zhou, Wenzhi Pan, Junbo Ge

“…Trial registration Trial registry: ClinicalTrials.gov. Unique identifying number: NCT05371366. Date of registration: 04/05/2022. …”
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Effects of minocycline on patients with acute anterior circulation ischaemic stroke undergoing intravenous thrombectomy (MIST-A): the study protocol for a multicentre, prospective,... by Xiao Zhang, Li Yao, Jingjing Zhao, Hao Zhu, Bin Wang, Huiping Zhang, Wen Jiang, Dong Wei, Wen Liu, Zhongqing Sun, Weiwang Li, Xiangjun Yuan, Xingshun Ma, Junpeng Meng, Yi Jia, Na Qin

“…The primary outcome will be assessed using a mixed-effects model to determine the association between treatment and outcomes.Ethics and dissemination The study is approved by the Ethics Committee of Xijing Hospital (XJLL-KY20222186) and is registered at ClinicalTrials.gov (NCT05487417). This trial is estimated to end in the first quarter of 2025 and study findings are expected to be published in scientific journals that undergo peer review and also to be showcased at scientific conferences.Trial registration number NCT05487417.…”
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The effectiveness of providing training and ongoing support to foster cultural humility in volunteers serving as mentors to youth of color: a mixed-methods study protocol by Bernadette Sánchez, Amy J. Anderson, Carla Herrera, David L. DuBois, Kay Thursby Bourke, Jean K. Sack, So Jung Lee, Karen Burchwell, Lidia Y. Monjaras-Gaytan, Yesenia Garcia-Murillo

“…Trial registration www.clinicaltrials.gov —Clinical Trial #NCT05391711; original 05.21.2022; Amendment 07.01.2022: study status was updated and more details were provided on outcome measures; Amendment 11/13/2022: sample size was modified, a few mentor outcome measures were added in the 12-months survey, the timing of a mentor measure was updated.…”
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Clinician’s perceptions and experiences with tobacco treatment in people who use cannabis: a qualitative study by Cristina Martínez, Marga Pla, Ariadna Feliu, Marta Enríquez, Judith Saura, Carmen Cabezas, Joan Colom, Josep M. Suelves, Sílvia Mondon, Pablo Barrio, Magalí Andreu, Antònia Raich, Jordi Bernabeu, Xavier Roca, Maite Narváez, Esteve Fernández, Group of clinicians of the ACT_ATAC study

“…Trial registration The ACT-ATAC project has been successfully registered at Clinicaltrials.gov [NCT04841655].…”
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Association Between Weight-Adjusted Waist Index and Cognitive Function in Older Adults Without Diabetes: A Cross-Sectional Study by Wang Q, Yin Y, Liu W, Li L, Wang Z, Tian Y, Fan J

“…Attaining an optimal WWI may be vital for cognitive decline, highlighting its role in a potential preventative approach.Clinical Trial Registry Number and Website Where It Was Obtained: The study design and data are publicly accessible at www.cdc.gov/nchs/nhanes/.Keywords: cognitive function, non-diabetic, NHANES, cross-sectional study, weight-adjusted-waist index, WWI…”
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Polysomnographic titration of non-invasive ventilation in motor neurone disease (3TLA): study protocol for a randomised controlled trial by David J. Berlowitz, Dominic Rowe, Mark E. Howard, Amanda Piper, Marnie Graco, Sabine Braat, Bhajan Singh, Tanara Viera Souza, Natasha Lannin, Alistair McLean, Abbey Sawyer, Kate A. Carey, Yasmin Ahamed, on behalf of the 3TLA Trial Group

“…Trial registration ClinicalTrials.gov NCT05136222. Registered on November 25, 2021.…”
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Effectiveness of eHealth literacy interventions: a systematic review and meta-analysis of experimental studies by Chiara Barbati, Elvira Maranesi, Cinzia Giammarchi, Matteo Lenge, Manila Bonciani, Elisa Barbi, Giacomo Pietro Vigezzi, Mauro Dragoni, Tania Bailoni, Anna Odone, Roberta Bevilacqua

“…Methods Following the PRISMA guidelines, we conducted a systematic review in PubMed/Medline, Scopus, Web of Science, Embase, Cochrane Library and ClinicalTrials.gov, including original experimental studies quantifying the effectiveness of interventions aimed at increasing eHL, as assessed by the eHealth Literacy Scale (eHEALS) or other validated scales. …”
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The effect of an app-based dietary education on dietary intake and cardiometabolic risk markers in people with type 2 diabetes: results from a randomized controlled trial by Linnea Sjöblom, Essi Hantikainen, Anna Dahlgren, Ylva Trolle Lagerros, Stephanie E. Bonn

“…Trial registration Registered at ClinicalTrials.gov ( NCT03784612 ). Registered 24 December 2018.…”
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Rapamycin-resistant polyclonal Th1/Tc1 cell therapy (RAPA-201) safely induces disease remissions in relapsed, refractory multiple myeloma by Lawrence G Lum, Parameswaran Hari, Aniko Szabo, Michele Donato, Jee Hyun Park, Daniel H Fowler, Binod Dhakal, Saurabh Chhabra, Deborah D Glass, David S Siegel, Tania C Felizardo

“…RAPA-201 therapy overcomes previous barriers to effective autologous polyclonal T-cell therapy, as it is feasible to manufacture, exquisitely safe to administer, and mediates remission in patients with RRMM.Trial registration number ClinicalTrials.gov: NCT04176380.…”
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Performance evaluation of the smartphone-based AI cough monitoring app - Hyfe Cough Tracker against solicited respiratory sounds [version 2; peer review: 1 approved, 2 approved wit... by Isabel Blavia, Juliane Chaccour, Eric M. Keen, Virginia Orrillo, Mindaugas Galvosas, Matthew Rudd, Juan C. Gabaldón-Figueira, Simon Grandjean Lapierre, Carlos Chaccour, Peter M. Small, Gerard Giménez

“…Methods: This study was embedded in a larger digital acoustic surveillance study (clinicaltrial.gov NCT04762693). Forty-nine participants were included and instructed to produce a diverse series of solicited sounds in 10-minute sessions. …”
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Generation Victoria (GenV): protocol for a longitudinal birth cohort of Victorian children and their parents by Elizabeth K. Hughes, William Siero, Alisha Gülenç, Susan A. Clifford, Tony Frugier, Simon M. Hall, Jatender Mohal, Kathryn North, Natasha Zaritski, Sharon Goldfeld, Richard Saffery, Melissa Wake

“…Trial registration ClinicalTrials.gov: NCT05394363; retrospectively registered 23 May 2022 (8 months into recruitment).…”
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Enhanced Recovery after Intensive Care (ERIC): study protocol for a German stepped wedge cluster randomised controlled trial to evaluate the effectiveness of a critical care telehe... by Ulrich Mansmann, Claudia Spies, Ursula Marschall, Reinhard Busse, Christine Adrion, Bjoern Weiss, Nicolas Paul, Elke Berger, Jörg Caumanns, Simone Rosseau

“…Study findings will also be disseminated via the website (www.eric-projekt.net).Trial registration number ClinicalTrials.gov Registry (NCT03671447).…”
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Inspiratory muscle training facilitates liberation from mechanical ventilation in subacute critically ill patients—a randomized controlled trial by Shu-Jane Wang, Tien-Pei Fang, Tien-Pei Fang, Daniel D. Rowley, Nan-Wei Liu, Jui-O Chen, Jui-Fang Liu, Jui-Fang Liu, Hui-Ling Lin, Hui-Ling Lin, Hui-Ling Lin

“…A moderate correlation between increased creatinine levels and respiratory muscle strength was observed, suggesting that creatinine may be a potential biomarker for muscle recovery during IMT.Clinical trial registrationThis study was registered at ClinicalTrials.gov (NCT06611683).…”
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Direct targeting of risk factors significantly increases the detection of liver cirrhosis in primary care: a cross-sectional diagnostic study utilising transient elastography by Guruprasad P Aithal, Indra Neil Guha, Stephen D Ryder, Emilie A Wilkes, David J Harman, Martin W James, Matthew Jelpke, Dominic S Ottey, Timothy R Card

“…Targeting risk factors using a non-invasive biomarker approach identified a substantial number of patients with previously undetected cirrhosis.Trial registration number The diagnostic algorithm utilised for this study can be found on clinicaltrials.gov (NCT02037867), and is part of a continuing longitudinal cohort study.…”
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RNA editing-based biomarker blood test for the diagnosis of bipolar disorder: protocol of the EDIT-B study by Andrea Miranda-Mendizabal, Diana Vetter, Juan Zambrano, Jeff Zarp, Victor Chavarría, Anna Giménez-Palomo, Meritxell Gonzalez-Campos, Marc Valenti, Lara Walczer Baldinazzo, Sara Siddi, Maurizio Ferrari, Dinah Weissmann, Chantal Henry, Josep Maria Haro, Lars Vedel Kessing, Eduard Vieta

“…Study registration: This study has been registered on clinicaltrials.gov (NCT05603819). Registration date: 28-10-2022.…”
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Risk analysis of cardiovascular toxicity in patients with lymphoma treated with CD19 CAR T cells by Yang Liu, Xiaoshuang Yuan, Xu Yang, Bo Yang, Guangyang Liu, Xiao Xu, Sanbin Wang, Zhixu He, Feiqing Wang, Yanju Li

“…Methods The PubMed, Embase, Cochrane library, and Web of Science databases were comprehensively searched from the time of their establishment to May 2024. The ClinicalTrials.gov English database is a comprehensive repository of the original studies of CD19 CAR T cell therapy and associated adverse outcomes, such as arrhythmia, CV events, and hypotension, in patients with lymphoma. …”
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Effectiveness of app-based cognitive behavioral therapy for insomnia on preventing major depressive disorder in youth with insomnia and subclinical depression: A randomized clinica... by Si-Jing Chen, Jian-Yu Que, Ngan Yin Chan, Le Shi, Shirley Xin Li, Joey Wing Yan Chan, Weizhen Huang, Chris Xie Chen, Chi Ching Tsang, Yuen Lam Ho, Charles M Morin, Ji-Hui Zhang, Lin Lu, Yun Kwok Wing

“…<h4>Trial registration</h4>ClinicalTrials.Gov (NCT04069247).…”
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