Efficacy and safety of Xiongzhitongluo granules in the treatment of acute ischemic stroke: study protocol for a randomized controlled trial by Yunmeng Chen, Jingjing Wei, Xiao Liang, Yue Liu, Lina Miao, Di Zhao, Yunfan Zhang, Hongxi Liu, Yunling Zhang

“…Written informed consent was obtained from all participants.Clinical trial registrationhttps://clinicaltrials.gov/, identifier, ChiCTR2200061859.…”
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Hand acceleration time (HAT) as a diagnostic tool in the assessment of haemodialysis access-induced distal ischaemia (HAIDI): study protocol for a prospective cohort study in the B... by Sebastian Videla, Begoña Gonzalo, Emma Espinar, Siloé Palacios, Carolina Herranz, Elena Iborra Ortega

“…Results will be published in peer-reviewed journals.Trial registration number ClinicalTrial.gov: NCT06187207. Pre Results.…”
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Ezetimibe Improves Rosuvastatin Effects on Inflammation and Vascular Endothelial Function in Acute Coronary Syndrome Patients Undergoing PCI by Changqing Sun, Wuyang Zheng, Ling Liang, Zuheng Liu, Wenchao Sun, Rong Tang

“…This trial is registered with https://clinicaltrials.gov/ct2/show/ChiCTR-IPR-17012219 (Chinese Clinical Trial Registry, http://www.chictr.org.cn on 02/08/2017).…”
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Long-term efficacy and safety of alemtuzumab in participants with highly active MS: TOPAZ clinical trial and interim analysis of TREAT-MS real-world study by Tjalf Ziemssen, Ann D. Bass, Bart Van Wijmeersch, Sara Eichau, Stephan Richter, Frank Hoffmann, Nicole M. Armstrong, Magdalena Chirieac, Janete Cunha-Santos, Barry A. Singer

“…Trial registration: ClinicalTrials.gov (CARE-MS I, NCT00530348; CARE-MS II, NCT00548405; CARE-MS Extension Study, NCT00930553; TOPAZ, NCT02255656). …”
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Health-Related Quality-of-Life Utility Values in Adults With Late-Onset Pompe Disease: Analyses of EQ-5D Data From the PROPEL Clinical Trial by Alison Griffiths, Simon Shohet, Neil Johnson, Alasdair MacCulloch

“…PROPEL was a Phase 3, double-blind, randomized controlled trial, which evaluated cipaglucosidase alfa plus miglustat, vs alglucosidase alfa plus placebo in 123 adult patients with LOPD (clinicaltrials.gov: NCT03729362). **Objectives:** To analyze EQ-5D health-related quality of life (HRQoL) utility data from PROPEL. …”
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Safety profile of EZH2 inhibitors for cancer: a systematic review and meta-analysis by Zhou Zhao, Xiufeng Chen, Huayang Pang, Yan Shi, Hao Sun

“…Databases searched included PubMed, Embase, CENTRAL (Cochrane Central Register of Controlled Trials), and ClinicalTrials.gov. Studies included were those involving patients treated with EZH2 inhibitors as monotherapy or in combination, specifically detailing the incidence of TRAEs. …”
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LMS MOODLE ЯК ЗАСІБ ОРГАНІЗАЦІЇ СЕРЕДОВИЩА ЗДОБУТТЯ ПЕДАГОГАМИ ПІСЛЯДИПЛОМНОЇ ОСВІТИ by Ірина Доманецька, Олена Федусенко, Олег Іларіонов, Ганна Красовська

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Interdisciplinary Team Pilot to Reduce Time to Administration of Piperacillin/Tazobactam in the Emergency Department at a Veterans Affairs Medical Center by DiVittorio MM, Fisher T, Steadman B, Cone B, Elfessi Z

“…Madeline M DiVittorio,1 Tracy Fisher,2 Brendan Steadman,2 Brian Cone,2 Zane Elfessi1– 3 1Department of Pharmacy, Jesse Brown Veterans Affairs Medical Center, Chicago, IL, USA; 2Department of Emergency Medicine, Jesse Brown Veterans Affairs Medical Center, Chicago, IL, USA; 3University of Illinois-Chicago College of Pharmacy, Chicago, IL, USACorrespondence: Zane Elfessi, Email zane.elfessi@va.govBackground: Sepsis is a condition of life-threatening organ dysfunction caused by a dysregulated host response to an infection. …”
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How and why a multifaceted intervention to improve adherence post-MI worked for some (and could work better for others): an outcome-driven qualitative process evaluation by Holly O Witteman, Laura Desveaux, Justin Presseau, Noah Michael Ivers, Marianne Saragosa, Kirstie Russell, Nicola McCleary, J-D Schwalm

“…To reach a broader and more diverse population, future iterations of the intervention should target aberrant beliefs about consequences, memory and decision-making and emotion.Trial registration number ClinicalTrials.gov registry; NCT02382731…”
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Performance and carcass characteristics of cattle with different castration practices by M. M. Anjos, V. S. Miler, B. N. Barboza, E. O. Queiroz, B. R. C. N. Pazdiora, G. A. Viana, R. D. Pazdiora

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СТРУКТУРА ІНФОРМАЦІЙНО - ОСВІТНЬОГО СЕРЕДОВИЩА МЕДИЧНОГО УНІВЕРСИТЕТУ by Наталя Іванькова, Олексій Рижов

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Improving the accUracy of Referrals to the emerGency departmEnt of patieNts with chesT pain using the modified HEART score in Emergency Medical Transport (URGENT 2.0): protocol for... by Joan G Meeder, Frits H M Van Osch, Robert T A Willemsen, Braim M Rahel, Lisa D S Frenk, Cees B de Vos, Fabiana G Prestigiacomo, Marcel J W Janssen, Arnoud W van 't Hof

“…The results of this trial will be disseminated in one main paper and in additional papers with subgroup analyses.Trial registration ClinicalTrials.gov, NCT04904107.…”
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ДОСВІД ВИКОРИСТАННЯ ХМАРНИХ СЕРВІСІВ ДЛЯ СПІЛЬНОЇ РОБОТИ НАУКОВОГО КЕРІВНИКА ТА АСПІРАНТІВ by Тетяна Вакалюк, Олег Спірін, Віктор Євдокимов, Анна Яцишин

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Feasibility of a pragmatic randomized adaptive clinical trial to evaluate a brief negotiational interview for harmful and hazardous alcohol use in Moshi, Tanzania. by Catherine A Staton, Kaitlyn Friedman, Ashley J Phillips, Mary Catherine Minnig, Francis M Sakita, Kennedy M Ngowi, Brian Suffoletto, Jon Mark Hirshon, Monica Swahn, Blandina T Mmbaga, Joao Ricardo Nickenig Vissoci

“…<h4>Trial registration</h4>Trial registration number NCT02828267. https://classic.clinicaltrials.gov/ct2/show/NCT02828267.…”
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Covid-19 e Câncer do Colo do Útero: Análise do Registro Hospitalar de Câncer do Instituto Nacional de Câncer no Rio de Janeiro by Monique Villa Real Ayala, Maria Tereza Fonseca da Costa

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Neuromuscular monitoring and incidence of postoperative residual neuromuscular blockade: a prospective observational study by Alessandra Piersanti, Rossella Garra, Fabio Sbaraglia, Miryam Del Vicario, Rosa Lamacchia, Marco Rossi

“…Trial registration The study was registered at ClinicalTrials.gov ( NCT06193213 , date of registration: 05/01/2024).…”
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Impact of multimorbidity on long-term outcomes in older adults with non-ST elevation acute coronary syndrome in the North East of England: a multi-centre cohort study of patients u... by Chris Wilkinson, Vijay Kunadian, Benjamin Beska, Abdulla A Damluji, Hanna Ratcovich, Greg B Mills

“…For each additional CCI comorbidity, on average, there was a 20% increased risk of the primary composite endpoint at 5 years (aHR 1.20 (1.09 to 1.33), p&lt;0.001).Conclusions In older adults with NSTE-ACS referred for coronary angiography, the presence of multimorbidity is associated with an increased risk of long-term adverse cardiovascular events, driven by a higher risk of all-cause mortality.Trial registration number NCT01933581; ClinicalTrials.gov.…”
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Opioid-free versus opioid-based anesthesia in laparoscopic sleeve gastrectomy: a single-center, randomized, controlled trial by Hanane Barakat, Linda Gholmieh, Jessy Abou Nader, Vanda Yazbeck Karam, Obey Albaini, Mohamad El Helou, Rony Al Nawwar

“…Trial registration ClinicalTrials.gov (NCT03507634); first trial registration date: 12/04/2018; first posted date: 25/04/2018.…”
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THE COLLABORATIVE DESIGNING OF A PERSONALIZED HYBRID LMS USING A VIRTUAL MACHINE IN A CLOUD ENVIRONMENT by Lina Čeponienė, Péter Galambos, Tamás Haidegger, Dariusz Mikulowski, Branislav Mišota, Oliver Moravcik, Enikő Nagy, Mariya P. Shyshkina, Pavel Smolka, Stefan Svetsky

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Cálculos de Estimativas de Câncer Regionais pela Razão Incidência/Mortalidade: Tutorial com Apoio de Scripts do Software R by Gil Patrus Pena, Sara Oliveira Ribeiro

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