Interface enhancement mechanism of rolled Mg/Al clad plate with particle interface control by Xiaobao Ma, Peng Li, Tao Wang, Zhongkai Ren, Peng Chen, Jiang Ji

“…In this study, the cold-spraying process was utilized to deposit Al particles onto an Al slab, an Mg slab, and both Al and Mg slabs to form an ultra-thin interlayer, and then the clad slabs were rolled at 400 °C, developing three roll-bonding processes: the roll-bonding process with cold-sprayed Al powder on the Al slab (CS-Al), the roll-bonding process with cold-sprayed Al powder on the Mg slab (CS-Mg), and the roll-bonding process with cold-sprayed Al powder on both the Al slab and the Mg slab (CS-Both). …”
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Monitoring M-Protein, Therapeutic Antibodies, and Polyclonal Antibodies in a Multiparametric Mass Spectrometry Assay Provides Insight into Therapy Response Kinetics in Patients wit... by Charissa Wijnands, Peter G. A. Karel, Jolein Gloerich, Gad Armony, Anastasia Tzasta, Corrie M. de Kat Angelino, Luciano Di Stefano, Vincent Bonifay, Theo M. Luider, Martijn M. VanDuijn, Sandra J. Croockewit, Elizabeth A. de Kort, Daan A. R. Castelijn, Claudia A. M. Stege, Hans J. C. T. Wessels, Alain J. van Gool, Niels W. C. J. van de Donk, Joannes F. M. Jacobs

“…Recently, we developed an ultra-sensitive mass spectrometry method to quantify minimal residual disease (MS-MRD) by targeting unique M-protein peptides. …”
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Melanin-like nanoparticles slow cyst growth in ADPKD by dual inhibition of oxidative stress and CREB by Yongzhan Sun, Quan Zou, Huizheng Yu, Xiaoping Yi, Xudan Dou, Yu Yang, Zhiheng Liu, Hong Yang, Junya Jia, Yupeng Chen, Shao-Kai Sun, Lirong Zhang

“…In this study, we synthesized ultra-small polyethylene glycol-incorporated Mn2+-chelated MNP (MMPP). …”
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Deep-Learning-Based Reconstruction of Single-Breath-Hold 3 mm HASTE Improves Abdominal Image Quality and Reduces Acquisition Time: A Quantitative Analysis by Felix Kubicka, Qinxuan Tan, Tom Meyer, Dominik Nickel, Elisabeth Weiland, Moritz Wagner, Stephan Rodrigo Marticorena Garcia

“…<b>Conclusions</b>: DL-HASTE is a robust abdominal MRI technique that improves image quality while at the same time reducing acquisition time compared with the routine clinical HASTE sequence. Using ultra-thin DL-HASTE-3 mm results in an even greater improvement with a similar SNR.…”
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Personalized allele-specific antisense oligonucleotides for GNAO1-neurodevelopmental disorder by Inna Shomer, Nofar Mor, Shaul Raviv, Noga Budick-Harmelin, Tanya Matchevich, Sharon Avkin-Nachum, Yoach Rais, Rebecca Haffner-Krausz, Ariela Haimovich, Aviv Ziv, Reut Fluss, Bruria Ben-Ze’ev, Gali Heimer, Denis N. Silachev, Vladimir L. Katanaev, Dan Dominissini

“…GNAO1-associated disorders are ultra-rare autosomal dominant conditions, which can manifest, depending on the exact pathogenic variant in GNAO1, as a spectrum of neurological phenotypes, including epileptic encephalopathy, developmental delay with movement disorders, or late-onset dystonia. …”
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Design and validation of a-SiC/SiN hybrid photonic platform for integrated quantum photonics by Naresh Sharma, Zizheng Li, Bruno Lopez-Rodriguez, Joey Vrugt, Stijn van der Waal, Luozhen Li, Roald van der Kolk, Philip J Poole, Dan Dalacu, Iman Esmaeil Zadeh

“…For example, the thin-film silicon nitride (SiN) platform provides ultra-low loss on the order of 0.1 dB m ^−1 , but is incompatible with dense integration , requiring large bending radii. …”
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Degradation kinetics, pathways, transformation products, and toxicity assessment of fluorochloridone in agricultural soils by Dong Zhao, Hongyu Chen, Shuo Shen, Enyu Lu, Junlong Feng, Hui Zhi, Lei Wang, Wei Li

“…Nine TPs were identified in soil using Ultra-Performance Liquid Chromatography Quadrupole-Orbitrap Mass Spectrometry (UPLC-Q-Exactive Orbitrap MS) and Compound Discoverer software, employing suspect and nontarget screening strategies. …”
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From the depths of the Java Trench: genomic analysis of Priestia flexa JT4 reveals bioprospecting and lycopene production potential by Ocky K. Radjasa, Ray Steven, Yosua Natanael, Husna Nugrahapraja, Septhy K. Radjasa, Tati Kristianti, Maelita R. Moeis, Joko P. Trinugroho, Haekal B. Suharya, Alfito O. Rachmatsyah, Ari Dwijayanti, Mutiara R. Putri, Charlie E. de Fretes, Zen L. Siallagan, Muhammad Fadli, Rafidha D. A. Opier, Jandinta D. Farahyah, Viana Rahmawati, Meirifa Rizanti, Zalfa Humaira, Ary S. Prihatmanto, Nugroho D. Hananto, R. Dwi Susanto, Agus Chahyadi, Elfahmi, Neil Priharto, Kamarisima, Fenny M. Dwivany

“…The presence of lycopene in the P. flexa JT4 cells was verified using Ultra-performance liquid chromatography-mass spectrometry (UPLC-MS/MS) in multiple reaction modes. …”
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Early risk assessment in paediatric and adult household contacts of confirmed tuberculosis cases by novel diagnostic tests (ERASE-TB): protocol for a prospective, non-interventiona... by Ursula Panzner, Katharina Kranzer, Tsitsi Bandason, Kuda Mutasa, Sandra Rukobo, Charles Sandy, Bariki Mtafya, Andrea Rachow, Norbert Heinrich, Michael Hoelscher, Judith Bruchfeld, Olena Ivanova, Nyanda Elias Ntinginya, Doreen Pamba, Laura Olbrich, Issa Sabi, Simeon Mwanyonga, Elmar Saathoff, Willyhelmina Olomi, Junior Mutsvangwa, Hazel M Dockrell, Edson Tawanda Marambire, Denise Banze, Alfred Mfinanga, Theodora D Mbunda, Khosa Celso, Gunilla Kallenius, Claire J Calderwood, Christof Geldmacher, Kathrin Held, Tejaswi Appalarowthu, Friedrich Rieß, Anna Shepherd, Christopher Sundling, Mishelle Mugava, Martha Chipinduro, Lwitiho Sudi, Antelmo Haule, Emmanuel Sichone, Paschal Qwaray, Harrieth Mwambola, Lilian Minja, Peter Edwin, Dogo Ngalison, Stella Luswema, Celina Nhamuave, António Machiana, Carla Madeira, Emelva Manhiça, Nádia Sitoe, Jorge Ribeiro

“…Individuals screening positive (WHO symptom screen or dCXR) will be requested to provide sputum for Xpert MTB/Rif Ultra. At baseline, HHCs will also be screened for HIV, diabetes (HbA1c), chronic lung disease (spirometry), hypertension and anaemia. …”
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Elucidating the pharmacological foundations and mechanisms of the Sihai Shuyu formula in treating Graves’ disease through integrated serum metabolomics and network pharmacology wit... by Xiaoju Liu, Xingjia Li, Wenbin Huang, Yifan Cui, Fengyun Cheng, Guofang Chen, Guofang Chen, Xiaodong Mao, Chao Liu, Chao Liu, Shuhang Xu

“…Hematoxylin-Eosin (H&amp;E) staining assessed the effects of these pharmacological interventions on thyroid gland tissues. Ultra-High Performance Liquid Chromatography with Quadrupole Time-of-Flight Mass Spectrometry (UPLC-Q-TOF-MS) was used in conjunction with network pharmacology and molecular docking to identify and predict SHSY’s active chemical components and targets. …”
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Human hair biochar to remove malachite green dye and bisphenol-A contamination by M. Kamaraj, P. Kamali, R. Kaviya, K. Abishek, B. Navinkumar, T.G. Nithya, L.S. Wong, J. Aravind

“…Data obtained from an Ultra Violet-Visible spectrophotometer was used to design expert software to calculate adsorption efficiency.  …”
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Indoor, outdoor, and personal exposure to PM2.5 and associated health risk in community-dwelling elderly residents in Fuzhou city, 2021: a cross-sectional study by Shuling KANG, Xin LIN, Kan LIN, Baoying LIU, Chuancheng WU, Jianjun XIANG, Jingwen CHEN, Quan ZHOU

“…PM2.5 concentration was measured with the weighing method; polycyclic aromatic hydrocarbons (PAHs) and metal elemental components in collected PM2.5 were determined by ultra-high performance liquid chromatography and inductively coupled plasma mass spectrometry. …”
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Features of expression of immunohistochemical markers in local and generalized clear cell kidney cancer by E. M. Frantsiyants, A. N. Shevchenko, E. A. Dzhenkova, N. S. Karnaukhov, T. A. Gudtskova, A. A. Breus, E. V. Filatova, D. A. Shvyrev

“…Used system detection UltraVision Quanto Detection System (Thermo Fisher Scientific), and the Chromogen DAB. …”
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Effect of Yanshiqiangxin Decoction on Cardiomyocyte Apoptosis in Heart Failure Rats Based on PI3K/Akt/Caspase-9 Signaling Pathway by ZHU Sixing, YAN Shiyun, XU Yan, QIN Yan, CHEN Liyun, JIA Meijun

“…One day after the last gavage, M-mode echocardiography [left ventricular ejection fraction (LVEF), left ventricular short-axis shortening (LVFS), left ventricular internal dimension diastole (LVIDd) and left ventricular internal dimension systole (LVIDs)] was performed through an ultra-high resolution small animal ultrasound imaging system; B-type natriuretic peptide (BNP) was measured by ELISA method; the apoptosis of cardiomyocytes was observed through laser confocal microscopy and the apoptosis index was calculated; the expression of apoptosis-related proteins Bax, Bcl-2 and PI3K/Akt/Caspase-9 signalling pathway proteins were detected by Western blot method.Results① Cardiac ultrasound test results: compared with the normal group, the left ventricular anterior wall motion waveform of the model group was not obvious, close to linear motion, and LVEF and LVFS decreased significantly (<italic>P</italic>&lt;0.05), LVIDd and LVIDs increased significantly (<italic>P</italic>&lt;0.05), the left ventricle was significantly enlarged and the contractility was reduced. …”
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Biological activities of Usnea lethariiformis lichen extracts and UHPLC-ESI-QTOF-MS analysis of their secondary metabolites by Mauricio Piñeiro, Mauricio Piñeiro, Sofía Manrique, Jessica Gómez, Jessica Gómez, Juan Manuel Rodriguez, Patricia Barrera, Duilio Caballero, Miguel A. Sosa, Gabriel Vargas-Arana, Gabriel Vargas-Arana, Alejandro Tapia, Beatriz Lima, Beatriz Lima, Mario J. Simirgiotis

“…The metabolite profiling was obtained using ultra-high-resolution liquid chromatography coupled with electrospray ionization quadrupole time-of-flight mass spectrometry (UHPLC-ESI-QTOF-MS) system. …”
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Evaluating small coronary stents with dual-source photon-counting computed tomography: effect of different scan modes on image quality and performance in a phantom by Thomas Stein, Constantin von zur Muhlen, Niklas Verloh, Till Schürmann, Tobias Krauss, Martin Soschynski, Dirk Westermann, Jana Taron, Elif Can, Christopher L. Schlett, Fabian Bamberg, Christopher Schuppert, Muhammad Taha Hagar

“…METHODS: Utilizing a phantom setup mimicking the average patient’s water-equivalent diameter, we examined six distinct coronary stents inflated in a silicon tube, with stent sizes ranging from 2.0 to 3.5 mm, applying four different CT acquisition modes of a dual-source PCD-CT scanner: “high-pitch,” “sequential,” “spiral” (each with collimation of 144 × 0.4 mm and full spectral information), and “ultra-high-resolution (UHR)” (collimation of 120 × 0.2 mm and no spectral information). …”
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The PANORAMIC Survey: Pure Parallel Wide Area Legacy Imaging with JWST/NIRCam by Christina C. Williams, Pascal A. Oesch, Andrea Weibel, Gabriel Brammer, Aidan P. Cloonan, Katherine E. Whitaker, Laia Barrufet, Rachel Bezanson, Rebecca A. A. Bowler, Pratika Dayal, Marijn Franx, Jenny E. Greene, Anne Hutter, Zhiyuan Ji, Ivo Labbé, Sinclaire M. Manning, Michael V. Maseda, Mengyuan Xiao

“…Pure parallel observing naturally creates a “wedding cake” survey with both wide and ultra-deep tiers, with 5 σ point-source depths at F444W ranging from 27.8–29.4 (ABmag), and with minimized cosmic variance. …”
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Ice-nucleating particles active below −24&thinsp;°C in a Finnish boreal forest and their relationship to bioaerosols by F. Vogel, F. Vogel, M. P. Adams, L. Lacher, P. B. Foster, G. C. E. Porter, G. C. E. Porter, B. Bertozzi, B. Bertozzi, K. Höhler, J. Schneider, T. Schorr, N. S. Umo, J. Nadolny, Z. Brasseur, P. Heikkilä, E. S. Thomson, N. Büttner, M. I. Daily, R. Fösig, A. D. Harrison, J. Keskinen, U. Proske, U. Proske, U. Proske, J. Duplissy, J. Duplissy, M. Kulmala, T. Petäjä, O. Möhler, B. J. Murray

“…Using the 6 <span class="inline-formula">min</span> time resolution PINE data, we present several lines of evidence that INPs below <span class="inline-formula">−</span>24 <span class="inline-formula">°C</span> in this location are also from biological sources: (i) an INP parameterization developed for a pine forest site in Colorado, where many INPs were shown to be biological, produced a good fit to our measurements; a moderate correlation of INPs with aerosol concentration larger than 0.5 <span class="inline-formula">µm</span> and the fluorescent bioaerosol concentration; (ii) a negative correlation with relative humidity that may relate to enhanced release of bioaerosol at low humidity from local sources such as the prolific lichen population in boreal forests; and (iii) the absence of correlation with ultra-fine particles (3.5 to 50 <span class="inline-formula">nm</span>), indicating that new particle formation events are not sources of INPs. …”
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Key experimental technologies and their development directions for the exploration and production of deep coalbed methane by Xia YAN, Fengyin XU, Xianyue XIONG, Feng WANG, Chunhu LI, Jiyuan ZHANG, Borui XU, Qianhui CHENG, Xiong HU, Xueguang ZHU, Wei LIANG, Pu YUAN, Yanqing FENG, Zhenji WEI

“…ProspectsThis study posits seven development directions for deep CBM production and in-situ coal conversion experiments: (1) Clear, direct observation techniques for micropores (< 2 nm) in deep coal seams with ultra-low porosity and permeability, full-scale pore size splicing technology for multiscale pore structure characterized by abundant micropores, a few mesopores, and many macropores, and assessment techniques for pore-fracture connectivity. (2) Isothermal adsorption test technologies for raw coals considering the effects of deep coal seam wettability, fracturing fluid invasion, and high total dissolved solids (TDS) under high-temperature, high-pressure in-situ conditions; (3) Sealed coring devices and in-situ pressure-retaining coring technologies featuring high pressure retaining success rates, heat preservation rates, and traceable gas volume. (4) Nanoscience-based assessment technologies for gas and water occurrence in micropores in deep coal seams under high-temperature and high-pressure multi-field coupling, and experimental technologies for desorption, diffusion, and seepage across nano-micro-millimeter scales. (5) Techniques for developing and testing multifunctional mechanical experiment equipment applicable to in-situ conditions of deep coal seams featuring high stress, low modulus of elasticity, and high Poisson's ratio. (6) Experimental techniques for the purpose of enhancing CBM recovery of deep coal seams, including reservoir stimulation (microwaves, laser, and electric heating), stimulation for permeability enhancement (electromagnetic pulses, pulsed ultrasonic waves, and controlled shockwaves), displacement via CO2 injection, and mechanical pulsation with supercritical CO2. (7) Experimental techniques for in-situ coal conversion and utilization, including pyrolysis, underground coal gasification (UCG), geothermal utilization, and CO2 geological storage. …”
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Implication of Galaxy-scale Negative Feedback by One of the Most Powerful Multiphase Outflows in a Hyperluminous Infrared Galaxy at Intermediate Redshift by Xiaoyang Chen, Masayuki Akiyama, Kohei Ichikawa, Yoshiki Toba, Toshihiro Kawaguchi, Takuma Izumi, Toshiki Saito, Daisuke Iono, Masatoshi Imanishi, Kianhong Lee, Hiroshi Nagai, Hirofumi Noda, Abdurro’uf, Mitsuru Kokubo, Naoki Matsumoto

“…Powerful galactic outflows driven by active galactic nuclei (AGNs) are commonly considered as one of the main mechanisms to regulate star formation in massive galaxies. Ultra- and hyperluminous IR galaxies (U/HyLIRGs) are thought to represent a transition phase of galaxies from a rapidly growing period to a quiescent status as gas is swept out by outflows, providing a laboratory in which to investigate outflows and their feedback effects on hosts. …”
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