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Suggested Topics within your search.
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Case Report: Targeted treatment by fluoxetine/norfluoxetine of a KCNC2 variant causing developmental and epileptic encephalopathy
Published 2025-01-01“…The Kv3.2 subfamily of voltage activated potassium channels encoded by the KCNC2 gene is abundantly expressed in neurons that fire trains of fast action potentials that are a major source of cortical inhibition. Gain-of-function (GOF) de novo pathogenic variants in KCNC1 and KCNC2, encoding Kv3.1 and Kv3.2 respectively, cause several types of epilepsy including developmental and epileptic encephalopathy (DEE). …”
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Features of the morphological structure of plants and biochemical properties of introduced and domestic varieties of Cannabis sativa L.
Published 2020-12-01“…Nowadays C. sativa is the main source of phyto material for industrial production of natural CBD. …”
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885
Tracing the Earliest Stages of Star and Cluster Formation in 19 Nearby Galaxies with PHANGS-JWST and HST: Compact 3.3 μm Polycyclic Aromatic Hydrocarbon Emitters and Their Relation...
Published 2025-01-01“…We establish a selection criteria based on a median color threshold of F300M − F335M = 0.67 at F335M = 20 and identify 1816 sources. …”
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Long-read sequencing of 945 Han individuals identifies structural variants associated with phenotypic diversity and disease susceptibility
Published 2025-02-01“…Abstract Genomic structural variants (SVs) are a major source of genetic diversity in humans. Here, through long-read sequencing of 945 Han Chinese genomes, we identify 111,288 SVs, including 24.56% unreported variants, many with predicted functional importance. …”
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Pollution Characteristics and Water Quality Status of Water Storage Pond in Xianyang City of Shaanxi Province
Published 2022-10-01“…Treatment methods suitable for the rural environment should be selected according to the characteristics of water pollution.…”
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Reduction of Total Phenols in Virgin Olive Oil as a Preservation Medium during Cold Storage of Whey Cheese and Tofu
Published 2024-01-01“…Virgin olive oil, known as a good source of health-promoting hydrophilic phenols, is traditionally used as a medium for preserving various foods. …”
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Spatial database applications for network analysis: Case study of bicycle accessibility of forested areas in the Poznań Metropolitan Area, Poland
Published 2024-12-01“…The solution includes a complete description of how to perform network analysis using a spatial database with SQL and pgRouting. The implemented functionalities consist of solutions for finding the equidistance or isochrone area for any selected point location. …”
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890
Building a Collaborative Editorial Workbench for Legal Texts with Complex Structures
Published 2020-05-01“…It introduces the reasons for selecting WordPress as the project’s CMS, the workflows established (including a sophisticated XSL-scripting pipeline), as well as three plug-ins created to integrate certain functionalities. …”
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Innovative Sandia Frequency Shift Islanding Detection for Microgrids Using Interval Type-II Fuzzy Logic and VP-PSO Optimization
Published 2025-01-01“…Using probability density functions (PDFs), multiple uncertainty scenarios were generated, with representative scenarios selected via Monte Carlo simulation (MCS) for IDM development. …”
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Memory Mining and Spatial Transformation of Daily Landscape in Renewal of Tianjin Old City
Published 2025-03-01“…Three novels by renowned Tianjin author Feng Jicai — Yin-Yang Eight Trigams, Three-Inch Golden Lotus, and Faces in the Crowd — are selected as primary data sources. Through text mining and semantic sentiment analysis, these works reveal three distinct emotional characteristics of daily landscapes. 1) Bustling Scenes: Positive emotional spaces, such as religious sites and venues associated with traditional artisans and eccentric figures, reflect the region’s commitment to preserving traditions and fostering a sense of collective enjoyment. …”
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Effects of exogenous sugars on root sugar metabolism and antioxidant system under sub-low root-zone temperature in Malus baccata Borkh.
Published 2025-07-01“…And, sugar not only serves as structural material and an energy source but also has signaling functions to regulate the expression of relevant genes and activities of relevant enzymes. …”
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mbctools: A User-Friendly Metabarcoding and Cross-Platform Pipeline for Analyzing Multiple Amplicon Sequencing Data across a Large Diversity of Organisms
Published 2024-12-01“…It provides functions for various tasks such as dereplication, clustering, chimera detection, and taxonomic assignment. …”
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Features of Visual Dysfunctions in Patients with Primary Hypothyroidism and Thyrotoxicosis
Published 2022-10-01“…The pattern of photosensitivity disorders, the topography of the location of the loci of local defects revealed by the short-wave infrared perimetry, indicate that the earliest signs of optical neuropathy are manifested at the level of photoreceptors — selectively in the S-cones. Decreased sensitivity to blue stimulus (440 nm) refers to an acquired color anomaly called tritanopia; which can be present with high visual function, is most often associated with a decrease in the number of S-cones and a deficiency of retinol (the source of cyanolab synthesis).…”
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Healthcare professional perspective on barriers and facilitators of multidisciplinary team working in acute care setting: a systematic review and meta-synthesis
Published 2025-03-01“…The aim of this study is to synthesise the factors that may act as barriers and facilitators to the work of multidisciplinary teams in managing labour within acute care settings.Design A systematic qualitative review and meta-synthesis was conducted following the five-step methodology proposed by Sandelowski et al.Data source Three databases (Medline, Embase and Scopus) were systematically searched without time restrictions up to 25 May 2024.Eligibility criteria for selecting studies Qualitative studies exploring perspectives, experiences and other similar factors were included. …”
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Spells and the Holy Tradition: On the Reception of the Biblical Heritage in the Verbal Magic of the Eastern Slavs
Published 2024-09-01“…The author investigates how these events and images get into the oral tradition, how they are assimilated into folklore, and what functions they perform in charms. The author relies on Holy Scripture and Sacred Tradition and uses apocryphal writings, liturgics, prayers, sermons, and other sources. …”
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German Colonists of Northwest Russia in Conditions of Post-Revolutionary Reality (1918-1922)
Published 2023-09-01“…The condition and functioning of German farms largely depended on the extraordinary revolutionary economic measures carried out by the Bolsheviks within the framework of equalizing land use and “war communism”, where the German village was considered as an easily accessible and high-performance source of agricultural resources for the Red Army and the urban population, which resulted in an excessively high economic burden on the colonies and a selective approach to accounting for national the specifics of the economic life of the Germans and their current economic opportunities. …”
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Methodology of recreation in the structure of the educational space
Published 2022-06-01“…Materials and Methods. Sources of information are publications in domestic literature. …”
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Association of microtubule-based processes gene expression with immune microenvironment and its predictive value for drug response in oestrogen receptor-positive breast cancer
Published 2025-07-01“…Transwell and cell viability assays were used to examine the biological functions of CHORDC1.ResultsTwo molecular subgroups with significantly different survival outcomes were identified. …”
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