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1301
Identification and molecular docking mechanism of novel anti-inflammatory peptides from Lactobacillus paraplantarum fermented Cannabis sativa L. (hemp) seeds
Published 2025-07-01“…Overall, these findings indicate that hemp seeds have potential to be a source of bioactive peptides for functional foods with anti-inflammatory properties.…”
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1302
Construction of cuproptosis-related genes risk model predicts the prognosis of Uterine Corpus Endometrial Carcinoma
Published 2025-01-01“…Differential gene expression was determined using LIMMA analysis, and functional enrichment analysis was conducted on identified cuproptosis-related genes. …”
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1303
Exploring Autophagy-Related Gene Expression in Hepatocellular Carcinoma via TCGA, GEPIA2, and HPA Databases: Implications for Prognosis
Published 2025-07-01“…RT-qPCR analysis further confirmed significant upregulation of mRNA expression levels of randomly selected BAG3, EIF2AK2, KIF5B, and RAB24 in HCC cell lines, consistent with the bioinformatics analysis findings.Conclusion: This study showed that the 41 obtained ARGs, such as ATG16L1, ATG4B, BAG3, KIF5B, MAPK1, RAB24, and SOGA1, these findings suggest that ARGs may serve as prognostic biomarkers for HCC, warranting further validation in clinical cohorts and functional studies.Keywords: hepatocellular carcinoma, bioinformatics, autophagy, prognostic markers, TCGA…”
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1304
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1305
Production of Bacterial β-Galactosidase Using Wastes of Dairy Industry
Published 2025-06-01“…A peak β-galactosidase activity of 5.523 U/ ml was recorded at a pH 7, a lactose concentration of 4.6 %, UF-cheese permeate serving as a carbon source, 2 % potassium nitrate (KNO₃) as a nitrogen source, an inoculum size of 5%, and incubated at 37 ºC for 24 h. …”
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1306
An effective fluorescence strategy based on xanthine oxidase catalysis and the carbon dots’ specific response to ·OH for aminophylline pharmacokinetic studies
Published 2025-08-01“…In this study, high quantum yield carbon dots (CA/EDA-CDs) were synthesized via a hydrothermal method using riboflavin as the carbon source, citric acid and ethylenediamine as functionalizing agents and dopants. …”
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1307
Humic acids as drivers of plant growth: regulating root development and photobiology through redox modulation
Published 2025-05-01“…These effects may be attributed to the interplay between the pro-oxidant (e.g., quinones and semiquinone radicals) and the antioxidant functionalities (e.g., polyphenols) inherent in HA, both contributing to the observed eustress response. …”
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1308
Methods for Adaptive Transformation of Content in Hypertext Format on Corporate TV and Information Kiosks of Educational Institutions
Published 2024-07-01“…The article also discusses how to level out the nuances associated with different resolutions of graphic images and screen orientation.Conclusion: the final paragraphs of the article conclude on the nuances of the functioning of the developed system, the effectiveness of which directly depends on methods of implementation and technologies used, chosen and discussed in the article. …”
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1309
An Evaluation of the Possibility of Using Buckwheat Hulls as an Addition to Bread
Published 2024-02-01“…Due to the high nutritional value of buckwheat hulls, which can be a great source of fibre, phenolics, minerals and some vitamins, the aim of the study was to assess the possibility of using it as a functional addition in bread production. …”
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1310
PEDAGOGICAL CONTENT THREE-FACTOR MODEL OF EDUCATING HIGH-SCHOOL STUDENTS FOR PROFESSIONAL ACTIVITIES
Published 2016-09-01“…The methods involve the analysis of a condition of higher education and the provisions of the Federal Law on Education regulating its functioning in the Russian Federation; text-centered approach to education of the person of culture – the professional specialist, responsible for the activities.Results and scientific novelty. …”
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1311
Bioinformatics-driven exploration of key genes and mechanisms underlying oxidative stress in traumatic brain injury
Published 2025-04-01“…This study aims to elucidate the potential molecular interactions between key genes associated with oxidative stress and their influence on TBI pathogenesis.MethodsTBI dataset and oxidative stress-related genes sourced from Public databases. Differential expression analysis and machine learning models were executed to select key genes, which were further validated using receiver operating characteristic (ROC) curves. …”
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1312
Fate and risks of potentially toxic elements associated with lacustrine groundwater discharge: quantification, modeling, and biogeochemistry
Published 2025-08-01“…Thus, self-organizing maps (SOM) and positive matrix factorization (PMF) were employed in present work to decipher source of selected PTE (Li, V, Mn, Cr, Co, Ni, Cu, Zn, Ba, Pb, U, Sr) in Ulansuhai Lake basin (Inner Mongolia, China). …”
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1313
Additive Manufacturing for Automotive Radar Sensors Using Copper Inks and Pastes
Published 2025-03-01“…Using the use-case “printing of heating coils on the inside of the front housing (primary radome)” needed for de-icing in winter, it is demonstrated that additive manufacturing (AM) can provide economic and functional benefits for manufacturing of the sensors. …”
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1314
Degradation of Tetracycline in Wastewater by Persulfate Activated by Sulfidated Nanometer Zero-valent Iron
Published 2024-07-01“…The primary pathways of TC degradation involve specific functional group cleavage and ring-opening reactions, ultimately leading to oxidative degradation into CO<sub>2</sub> and H<sub>2</sub>O.…”
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1315
Prediction of Alzheimer’s Disease Based on Multi-Modal Domain Adaptation
Published 2025-06-01“…<b>Background/Objectives:</b> Structural magnetic resonance imaging (MRI) and 18-fluoro-deoxy-glucose positron emission tomography (PET) reveal the structural and functional information of the brain from different dimensions, demonstrating considerable clinical and practical value in the computer-aided diagnosis of Alzheimer’s disease (AD). …”
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1316
Exploring exhaled breath biomarkers for lactose intolerance diagnosis: the Lactobreath pilot study protocol
Published 2025-08-01“…Diagnosis is complicated as food intolerance is often associated with functional GI disorders, while FODMAPs may exert their effects individually or in combination. …”
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1317
Decellularized porcine liver scaffold for maintaining the viability and capacity of pancreatic islets
Published 2025-03-01“…Bioengineered pancreatic constructs based on scaffolds made from decellularized tissues and pancreatic islets (PIs) may be used to extend the functional activity of transplanted PIs in patients with type I diabetes. …”
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1318
HERV-derived epitopes represent new targets for T-cell-based immunotherapies in ovarian cancer
Published 2025-08-01“…Human endogenous retroviruses (HERVs) are aberrantly expressed by tumor cells and may represent a source of shared T-cell epitopes for cancer immunotherapy regardless of the tumor mutational burden.Methods A transcriptomic analysis based on RNA sequencing was developed to quantify the expression of HERV-K sequences containing the selected epitopes. …”
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1319
Feasibility, Added Value, and Radiation Dose of Combined Coronary CT Angiography and Stress Dynamic CT Myocardial Perfusion Imaging in Moderate Coronary Artery Disease: A Real-Worl...
Published 2025-06-01“…Conclusion: The combined CCTA and dynamic CT-MPI protocol is feasible in real-world clinical practice and offers a comprehensive morphological and functional assessment of moderate CAD, with a manageable radiation dose and examination time.…”
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1320
Evaluation of Southern African wild edible plants for potential herb-drug interactions through ex vivo p-glycoprotein and in vitro cytochrome P450 3A4 inhibitory effects
Published 2025-02-01“…The herb/food-drug interactions also present opportunities for discovery of new functional excipients for enhancing the permeability of poorly absorbed orally administered drugs that are substrates of P-gp and CYP3A4.…”
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