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681
3D printing-biomimetic local stiff niche enhances glycolysis to boost PDAC cell stem-like phenotype via N6-methyladenosine-suppressed YAP1 mRNA decay
Published 2025-10-01“…Cancer stem cells (CSCs), the primary source of therapy resistance in pancreatic ductal adenocarcinoma (PDAC), exist in a dynamic equilibrium through tumor microenvironment (TME)-driven plasticity. …”
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682
A co-feeding strategy of formate and H2 for methanogens – Enhancing growth parameters and methane production
Published 2025-03-01“…In this study, formate served as an energy and carbon source for methane production with a formatotrophic mixed culture. …”
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683
ROS and cGMP signaling modulate persistent escape from hypoxia in Caenorhabditis elegans.
Published 2022-06-01“…The ability to detect and respond to acute oxygen (O2) shortages is indispensable to aerobic life. …”
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684
Regulation of xanthine dehydrogensase gene expression and uric acid production in human airway epithelial cells.
Published 2017-01-01“…<h4>Introduction</h4>The airway epithelium is a physical and immunological barrier that protects the pulmonary system from inhaled environmental insults. Uric acid has been detected in the respiratory tract and can function as an antioxidant or damage associated molecular pattern. …”
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685
Polymorphisms of an innate immune gene, toll-like receptor 4, and aggressive prostate cancer risk: a systematic review and meta-analysis.
Published 2014-01-01“…<h4>Background</h4>Toll-like receptor 4 (TLR4) is one of the best known TLR members expressed on the surface of several leukocytes and tissue cells and has a key function in detecting pathogen and danger-associated molecular patterns. …”
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686
Intercropping and Nitrogen Fertilization Altered the Patterns of Leaf Senescence in Sorghum
Published 2021-01-01“…Effects of competition in sorghum-legume intercropping and source-sink relationships on the patterns of leaf senescence deserve further investigation.…”
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687
The 4–400 GHz Survey for the 32 Class II Disks in the Taurus Molecular Cloud
Published 2025-01-01“…We have compiled the ∼4–400 GHz broad spectra of 32 Class II protoplanetary disks (PPDs) in the Taurus-Auriga region, which represents the brightest one-third of sources detected in the submillimeter band in this region. …”
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688
Feeding black soldier fly (Hermetia illucens) larvae with mushrooms and then exposing them to UVB produces larvae extremely rich in vitamins D2 and D3
Published 2025-12-01“…Black soldier fly larvae (BSFL) are a sustainable source of protein for feed but they can also be a sustainable source of some phytochemicals due to their ability to bioaccumulate them. …”
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689
State of the art in remote sensing monitoring of carbon dynamics in African tropical forests
Published 2025-03-01“…Future developments in remote sensing should examine how multi-sensor integration of high-resolution data from instruments such as Planet, Tandem-X, SPOT and improved AI methods can refine forest composition, carbon storage and function maps, enhance large-scale monitoring of tree height and biomass dynamics, and improve forest degradation and deforestation detection down to tree level. …”
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690
REVISITING THE ORGANIZATION OF A CLINICAL (MEDICAL) PSYCHOLOGIST WORK AT THE FIRST STAGE OF MEDICAL REHABILITATION IN THE CONDITIONS OF THE INTENSIVE CARE UNIT (ICU) BY THE EXAMPLE...
Published 2025-03-01“…There is currently a pressing need to devise a way of neurophycological diagnostics of higher mental functions which would allow to detect cognitive impairment in patients in the ICU during the first stages of medical rehabilitation taking into account working hours constraints.…”
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691
The Role of High-mass Stellar Binaries in the Formation of High-mass Black Holes in Dense Star Clusters
Published 2025-01-01“…Recent detections of gravitational waves from mergers of binary black holes (BBHs) with premerger source-frame individual masses in the so-called upper mass gap, expected due to (pulsational) pair instability supernovae ((P)PISNe), have created immense interest in the astrophysical production of high-mass black holes (BHs). …”
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692
De Novo Synthesis of Anticholinergic Hyoscyamine and Scopolamine in <i>Nicotiana benthamiana</i> Based on Elucidating Tropane Alkaloid Biosynthetic Pathway of <i>Anisodus luridus</...
Published 2024-10-01“…Its high yield of hyoscyamine makes <i>A. luridus</i> a valuable plant source for commercially producing TAs. In this study, we conduct homologous gene research across transcriptome data of different tissues together with functionally tested sequences in <i>Atropa belladonna</i> as a reference and identify 13 candidate genes for TAs biosynthesis in <i>A. luridus</i>. …”
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693
Assessing the impact of a rare synonymous variant in the <i>KNG1</i> gene on the development of hereditary angioedema
Published 2024-01-01“…Therefore, (1) the mutant high-molecular-weight kininogen is more easily activated by kallikrein and becomes a source of bradykinin formation through the kallikrein-kinin system; (2) the mechanism of bradykinin formation undergoes significant changes and results in the formation of functionally active but aberrant bradykinin, which alters its inactivation by enzymes with a consequent increase in its half-life, (3) the changes in positions 380-389 bring about modifications in Lys-bradykinin reproduction such that in subsequent steps it is “easily” cleaved to bradykinin by arginine aminopeptidase. …”
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694
Enabling beam-scanning antenna technologies for terahertz wireless systems: A review
Published 2025-03-01“…While producing a scannable highly-directive antenna beam proves to be indispensable in the period of microwaves, the significance of such functionality is more critical in the THz era, considering that THz waves have more intractable challenges such as the severity of free-space propagation losses, the susceptibility to atmospheric environments, and the unavailability of efficient signal sources. …”
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695
Thermally radiative water-based hybrid nanofluid with nanoparticles and gyrotactic microorganisms past a stretching surface with convective conditions and porous media
Published 2025-01-01“…The analysis is done via the bvp4c MATLAB function in order to analyze the current model numerically by implementing convective boundary conditions. …”
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696
Differential expression of five genes during sclerotium formation of Rhizoctonia solani
Published 2013-01-01“…Rhizoctonia solani is an important plant pathogenic fungus with a wide host range and worldwide distribution, and the sclerotia are the main source of infection for the diseases caused by this pathogen. …”
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697
Complexation with Alginate in Pumpkin Leaf Protein Solutions for the Encapsulation of Folic Acid: The Effect of Extraction Protocols
Published 2024-11-01“…This study aimed to assess pumpkin leaves as a protein source and determine the feasibility of these proteins to form complexes with alginate for the encapsulation of folic acid. …”
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698
Bioactives and Other Nutritional Components in the Jaggery Production Process
Published 2024-02-01“…Jaggery, a non-centrifugal sugar (NCS), is a naturally produced sweetener and a good source of minerals, essential vitamins and bioactives. …”
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699
Solar background radiation temperature calibration of a pure rotational Raman lidar
Published 2025-03-01“…It also allows a lidar not co-located with a routine external source to be continuously calibrated once an initial external calibration is done. …”
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700
Identification of multiple power quality disturbances in hybrid microgrid using deep stacked auto-encoder based bi-directional LSTM classifier
Published 2025-03-01“…In recent years microgrid technology has created widespread interest for the integration of renewable energy sources into main utility grid to supply clean energy to the end users. …”
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