Voice EHR: introducing multimodal audio data for health by James Anibal, James Anibal, Hannah Huth, Ming Li, Lindsey Hazen, Veronica Daoud, Dominique Ebedes, Yen Minh Lam, Hang Nguyen, Phuc Vo Hong, Michael Kleinman, Shelley Ost, Christopher Jackson, Laura Sprabery, Cheran Elangovan, Balaji Krishnaiah, Lee Akst, Lee Akst, Ioan Lina, Iqbal Elyazar, Lenny Ekawati, Stefan Jansen, Richard Nduwayezu, Charisse Garcia, Jeffrey Plum, Jacqueline Brenner, Miranda Song, Emily Ricotta, Emily Ricotta, David Clifton, C. Louise Thwaites, Yael Bensoussan, Bradford Wood

“…Existing technologies depend on limited datasets collected with expensive recording equipment in high-income countries, which challenges deployment in resource-constrained, high-volume settings where audio data may have a profound impact on health equity.MethodsThis report introduces a novel protocol for audio data collection and a corresponding application that captures health information through guided questions.ResultsTo demonstrate the potential of Voice EHR as a biomarker of health, initial experiments on data quality and multiple case studies are presented in this report. …”
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Mitral Valve Repair by Irbaz Hameed, MD, Adham Ahmed, BS, Christina Waldron, BS, Percy T. Algarate, MD, Michal Kawczynski, MD, Maurish Fatima, MBBS, BS, Amnah Alhazmi, MBBS, Samantha Colon, BS, Alexandria Brackett, MA, MLIS, Samuel Heuts, MD, PhD, Peyman Sardari Nia, MD, PhD, Mario Gaudino, MD, PhD, Vinay Badhwar, MD, Arnar Geirsson, MD

“…The primary outcomes were long-term survival, freedom from reoperation, and freedom from recurrent mitral regurgitation (moderate-severe). A novel meta-analytic volume-outcome approach using reconstructed Kaplan-Meier-derived individual patient data from the original studies was used. …”
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Binding of LncDACH1 to dystrophin impairs the membrane trafficking of Nav1.5 protein and increases ventricular arrhythmia susceptibility by Genlong Xue, Jiming Yang, Yang Zhang, Ying Yang, Ruixin Zhang, Desheng Li, Tao Tian, Jialiang Li, Xiaofang Zhang, Changzhu Li, Xingda Li, Jiqin Yang, Kewei Shen, Yang Guo, Xuening Liu, Guohui Yang, Lina Xuan, Hongli Shan, Yanjie Lu, Yang Baofeng, Zhenwei Pan

“…The human homologue of lncDACH1 inhibited the membrane distribution of Nav1.5 in human iPS-differentiated cardiomyocytes. The findings provide novel insights into the mechanism of Nav1.5 membrane targeting and the development of ventricular arrhythmias.…”
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Investigating and Completing Khanlari’s Theory on Metrical Units by Abbas Jahed Jah

“…This study demonstrates that by completing and refining Khanlari’s approach, it is capable of describing Persian poetic meter, providing a novel understanding of the nature of metrical patterns, and can aid in simplifying the teaching of prosody while deepening its comprehension. …”
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From plants to patterns: Constructing a comprehensive online strontium isoscape for Belgium (IsoBel) using high density grid mapping by Amanda Sengeløv, Giacomo Capuzzo, Sarah Dalle, Hannah F. James, Charlotte Sabaux, Elisavet Stamataki, Marta Hlad, Carina T. Gerritzen, Emma M. Legrand, Barbara Veselka, Guy De Mulder, Rica Annaert, Mathieu Boudin, Kevin Salesse, Eugène Warmenbol, Nadine Mattielli, Christophe Snoeck, Martine Vercauteren

“…Sampling sites were selected to cover diverse lithological formations and soil types, ensuring representative coverage of the region’s geological heterogeneity, by using a novel high density grid mapping method. Sixty-four previously published plants from 21 locations are also included in this study, bringing the total amount of plant samples used to 604 from 220 locations. …”
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Retrieving the atmospheric concentrations of carbon dioxide and methane from the European Copernicus CO2M satellite mission using artificial neural networks by M. Reuter, M. Hilker, S. Noël, A. Di Noia, M. Weimer, O. Schneising, M. Buchwitz, H. Bovensmann, J. P. Burrows, H. Bösch, R. Lang

“…Since CO2M will not be launched until 2026, our study exploits simulated measurements over land surfaces from a comprehensive observing system simulation experiment (OSSE) that includes realistic meteorology, aerosols, surface bidirectional reflectance distribution function (BRDF), solar-induced chlorophyll fluorescence (SIF), and CO<span class="inline-formula">₂</span> and CH<span class="inline-formula">₄</span> concentrations. We created a novel hybrid learning approach that combines advantages of simulation-based and measurement-based training data to ensure coverage of a wide range of XCO<span class="inline-formula">₂</span> and XCH<span class="inline-formula">₄</span> values, making the training data representative of future concentrations as well. …”
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Single-Photon Detectors for Quantum Integrated Photonics by Thu Ha Dao, Francesco Amanti, Greta Andrini, Fabrizio Armani, Fabrizio Barbato, Vittorio Bellani, Vincenzo Bonaiuto, Simone Cammarata, Matteo Campostrini, Samuele Cornia, Fabio De Matteis, Valeria Demontis, Giovanni Di Giuseppe, Sviatoslav Ditalia Tchernij, Simone Donati, Andrea Fontana, Jacopo Forneris, Roberto Francini, Luca Frontini, Gian Carlo Gazzadi, Roberto Gunnella, Ali Emre Kaplan, Cosimo Lacava, Valentino Liberali, Leonardo Martini, Francesco Marzioni, Claudia Menozzi, Elena Nieto Hernández, Elena Pedreschi, Paolo Piergentili, Paolo Prosposito, Valentino Rigato, Carlo Roncolato, Francesco Rossella, Matteo Salvato, Fausto Sargeni, Jafar Shojaii, Franco Spinella, Alberto Stabile, Alessandra Toncelli, Gabriella Trucco, Valerio Vitali

“…This review explores the state of the art of single-photon detector research and examines the potential breakthroughs offered by novel low-dimensional materials in this field.…”
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Triglyceride-glucose-body mass index and the incidence of cardiovascular diseases: a meta-analysis of cohort studies by Xiyun Rao, Ziyi Xin, Qingwen Yu, Lanlan Feng, Yongmin Shi, Ting Tang, Xuhan Tong, Siqi Hu, Yao You, Shenghui Zhang, Jiake Tang, Xingwei Zhang, Mingwei Wang, Ling Liu

“…This study aims to summarize the correlation between the triglyceride-glucose-body mass index (TyG-BMI index), a novel surrogate indicator of insulin resistance, and the incidence of CVD in patients without CVD at baseline through meta-analysis. …”
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WALLABY Pilot Survey: Star Formation Enhancement and Suppression in Gas-rich Galaxy Pairs by Qifeng Huang, Jing Wang, Xuchen Lin, Se-Heon Oh, Xinkai Chen, B. Catinella, N. Deg, H. Dénes, B. -Q. For, B. S. Koribalski, K. Lee-Waddell, J. Rhee, A. X. Shen, Li Shao, K. Spekkens, L. Staveley-Smith, T. Westmeier, O. I. Wong, A. Bosma

“…We obtain individual masses of atomic hydrogen (H i ) for these paired galaxies using a novel deblending algorithm for H i data cubes. Quantifying the interaction stages and strengths with parameters motivated by first-principles analysis, we find that, at fixed stellar and H i mass, the alteration in the SFR of galaxy pairs starts when their dark matter halos are encountered. …”
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Niraparib restricts intraperitoneal metastases of ovarian cancer by eliciting CD36-dependent ferroptosis by Ning Jin, Yi-yu Qian, Xiao-fei Jiao, Zhen Wang, Xin Li, Wen Pan, Jin-kai Jiang, Pu Huang, Si-yuan Wang, Ping Jin, Qing-lei Gao, Dan Liu, Yu Xia

“…Our findings demonstrate ferroptosis as a novel mechanism underlying the regression of OC metastases induced by niraparib, thereby offering tantalizing prospects for the frontline application of this agent in the management of OC.…”
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Subgenome asymmetry of gibberellins-related genes plays important roles in regulating rapid growth of bamboos by Ling Mao, Cen Guo, Liang-Zhong Niu, Yu-Jiao Wang, Guihua Jin, Yi-Zhou Yang, Ke-Cheng Qian, Yang Yang, Xuemei Zhang, Peng-Fei Ma, De-Zhu Li, Zhen-Hua Guo

“…The subgenome asymmetry was found to be correlated with the subgenome-specific gene structure, particularly UTRs and core promoters. Our study provides novel insights into the molecular mechanism and evolution of rapid shoot growth following allopolyploidization in woody bamboos, particularly via subgenome asymmetry. …”
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Cancer cells avoid ferroptosis induced by immune cells via fatty acid binding proteins by Maria Angelica Freitas-Cortez, Fatemeh Masrorpour, Hong Jiang, Iqbal Mahmud, Yue Lu, Ailing Huang, Lisa K. Duong, Qi Wang, Tiffany A. Voss, Claudia S. Kettlun Leyton, Bo Wei, Wai-Kin Chan, Kevin Lin, Jie Zhang, Efrosini Tsouko, Shonik Ganjoo, Hampartsoum B. Barsoumian, Thomas S. Riad, Yun Hu, Carola Leuschner, Nahum Puebla-Osorio, Jing Wang, Jian Hu, Michael A. Davies, Vinay K. Puduvalli, Cyrielle Billon, Thomas P. Burris, Philip L. Lorenzi, Boyi Gan, James W. Welsh

“…Conclusions Our study uncovers a novel mechanism by which cancer cells evade immune-mediated ferroptosis through Fabp7 upregulation. …”
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New Horizons In The Treatment Of Metastatic Castrate Resistant Prostate Cancer by Zein El Amir

“…If anything, the conditions of anatomy learning, despite the incorporation of novel technologies, are worsening in medical institutions, leading to potentially grave consequences for the future of healthcare. …”
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The study of interactome in Russian patients with Usher syndrome to select priority approaches in pathogenetically oriented treatment by M.E. Ivanova, D.S. Atarshchikov, A.M. Demchinsky, V.V. Strelnikov, D. Barh, G.V. Poryadin, L.M. Balashova, J.M. Salmasi

“…MYO7A: p.Q18* was the most common (27.27%) mutation associated with early and the most severe clinical manifestations. Two novel mutations (p.E1301* и c.158-?_318+?del) were identified in PCDH15 gene. …”
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Anatomy In The Undergraduate Medical Curriculum; Blending The Old And New by Ayesha Yousaf

“…If anything, the conditions of anatomy learning, despite incorporation of novel technologies, are worsening in medical institutions, leading to potentially grave consequences for the future of healthcare. …”
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Individualized prediction of multi-domain intelligence quotient in bipolar disorder patients using resting-state functional connectivity by Xiaoyu Li, Wei Wei, Linze Qian, Xiaojing Li, Mingli Li, Ioannis Kakkos, Qiang Wang, Hua Yu, Wanjun Guo, Xiaohong Ma, George K. Matsopoulos, Liansheng Zhao, Wei Deng, Yu Sun, Tao Li

“…It is a step toward the development of applicable techniques for quantitative and objective cognitive assessment in BD patients and contributes novel insights into understanding the complex neural mechanisms underlying different IQ domains.…”
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Microbial metabolites and immune modulation by Hassan Ghasemi

“…These findings underscore the potential of leveraging microbial metabolites to improve vaccine efficacy, particularly in immunocompromised populations or during outbreaks of novel pathogens.13 However, challenges in this field persist. …”
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Protocol for engineering bone organoids from mesenchymal stem cells by Jian Wang, Dongyang Zhou, Ruiyang Li, Shihao Sheng, Guangfeng Li, Yue Sun, Peng Wang, Yulin Mo, Han Liu, Xiao Chen, Zhen Geng, Qin Zhang, Yingying Jing, Long Bai, Ke Xu, Jiacan Su

“…This in vivo bone organoid model offers a novel platform for studying bone development, exploring congenital diseases, testing drugs, and developing therapeutic applications.…”
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Human GM-CSF/IL-3 enhance tumor immune infiltration in humanized HCC patient-derived xenografts by Kelley Weinfurtner, David Tischfield, George McClung, Jennifer Crainic, John Gordan, Jing Jiao, Emma E. Furth, Wuyan Li, Erena Tuzneen Supan, Gregory J. Nadolski, Stephen J. Hunt, David E. Kaplan, Terence P.F. Gade

“…Leveraging xenograft tumors derived from patients with unresectable HCCs and a commercially available immunodeficient mouse strain that expresses human GM-CSF and IL-3, we demonstrate a novel but accessible approach for modeling the HCC tumor microenvironment.…”
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NSUN5 Facilitates Hepatocellular Carcinoma Progression by Increasing SMAD3 Expression by Hexu Han, Chengcheng zhang, Wenbo Shi, Jiawei Wang, Wenhui Zhao, Yanping Du, Zhibin Zhao, Yifan Wang, Maosong Lin, Lei Qin, Xiaoxue Zhao, Qianqian Yin, Yiyi Liu, Zhongqi Wang, Jing Zhang, Xiaomin You, Guoxiong Zhou, Honghui Wu, Jun Ye, Xianzhong He, Weizhong Tian, Hong Yu, Yin Yuan, Qiang Wang

“…Collectively, this study identifies NSUN5 as a novel driver of metastasis in HCC and provides a theoretical foundation for potential therapeutic strategies against this malignancy.…”
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