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18801
Frictional heat-assisted performance enhancement in dynamic Schottky contact of Al/Ag2Se-based tribovoltaic nanogenerator
Published 2025-01-01“…The tribovoltaic nanogenerator (TVNG) has evolved in recent years as a novel type of nanogenerator designed to address the limitations of the standard triboelectric nanogenerator in terms of output signal and charge generation. …”
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18802
Effectiveness and Side Effect Incidence in a Real-World Digital Weight-Loss Service Using Compounded Semaglutide: A Retrospective Comparative Study
Published 2024-10-01“…Although compounding has been relatively common over the past century, prominent medical bodies have argued that compounding a relatively novel medication such as Semaglutide represents a major safety risk. …”
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18803
Identification of a 5-Gene-Based Scoring System by WGCNA and LASSO to Predict Prognosis for Rectal Cancer Patients
Published 2021-01-01“…Our present study was aimed at developing a novel prognostic signature panel for RC. Methods. …”
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18804
Blood-brain barrier breakdown in brain ischemia: Insights from MRI perfusion imaging
Published 2025-01-01“…Finally, in this review, we explore the implications of the mentioned neuroimaging findings, which emphasize the potential of neuroimaging biomarkers to guide personalized treatment and inform novel neuroprotective strategies. This review highlights the importance of investigating BBB changes in brain ischemia and the critical role of advanced neuroimaging in improving patient care and advancing stroke research.…”
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18805
Coactivation of Tie2 and Wnt signaling using an antibody–R-spondin fusion potentiates therapeutic angiogenesis and vessel stabilization in hindlimb ischemia
Published 2024-12-01“…These results indicate that the agonistic synergism of Tie2 and Wnt/β-catenin signaling achieved using T11–RF12 is a novel therapeutic option with potential for treating limb ischemia and other ischemic diseases.…”
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18806
Radiation dose and fraction in immunotherapy: one-size regimen does not fit all settings, so how does one choose?
Published 2021-04-01“…Hypofractionation or other modifications of standard fractionation may improve radiation’s ability to promote immune responses to tumors. Other novel delivery options may also affect immune responses, including T-cell activation and tumor-antigen presentation changes. …”
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18807
Biomimetic polydopamine loaded with janus kinase inhibitor for synergistic vitiligo therapy via hydrogel microneedles
Published 2025-01-01“…Results In this study, we introduce a novel therapeutic agent called PDA-JAKi, which is capable of both eliminating oxidative stress and inhibiting T cell activation. …”
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18808
Kinetic origin of hysteresis and the strongly enhanced reversible barocaloric effect by regulating the atomic coordination environment
Published 2024-10-01“…These results reveal the atomic-scale mechanism regulating hysteresis and provide insights into tailoring the functional properties of novel caloric refrigeration materials.…”
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18809
Overexpression of multiple cytochrome P450 genes with and without knockdown resistance mutations confers high resistance to deltamethrin in Culex quinquefasciatus
Published 2025-01-01“…The kdr L1014F mutation was found in Cq_SP-R and its parent Cq_SP strains with a significantly higher mutant allele frequency in the survivor mosquitoes than in dead mosquitoes (P < 0.0001). The V240M and novel L925F mutations were found only in Cq_SP-R strain. …”
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18810
Ecological impacts of single-axis photovoltaic solar energy with periodic mowing on microclimate and vegetation
Published 2025-02-01“…In the state of California’s Great Central Valley (United States), we developed a novel experimental framework to characterize five distinct “micro-patches” that capture the full spectrum of microclimate and vegetation zones modulated by the tracking PV system and O&M. …”
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18811
Carbohydrate ligand engagement with CD11b enhances differentiation of tumor-associated myeloid cells for immunotherapy of solid cancers
Published 2023-06-01“…These findings could pave the way for the development of safe and novel BG34-200-based therapies that modulate myeloid-derived cell functions, thereby enhancing immunotherapy for solid cancers.…”
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18812
Mapping QTL for Root and Shoot Morphological Traits in a Durum Wheat × T. dicoccum Segregating Population at Seedling Stage
Published 2017-01-01“…Moreover, meta-QTL analysis was performed to compare the QTL identified in the “Simeto” × “Molise Colli” segregating population with those described in previous studies in wheat, with three novel QTL defined. Due to the complexity of phenotyping for root traits, further studies will be helpful to validate these regions as targets for breeding programs for optimization of root function for field performance.…”
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18813
Identifying disulfidptosis-related biomarkers in epilepsy based on integrated bioinformatics and experimental analyses
Published 2025-02-01“…Disulfidptosis, a proposed novel cell death mechanism, is thought to play a part in the pathogenesis of epilepsy, but the exact role is unclear. …”
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18814
Mycochemistry, antioxidant, anticancer activity, and molecular docking of compounds of F12 of ethyl acetate extract of Astraeus asiaticus with BcL2 and Caspase 3
Published 2025-02-01“…In conclusion, F12 fraction of AAEA extract of this mushroom containing six bioactive compounds was a promising antioxidant and anticancer agent and the use of this fraction in cancer treatment will be a novel study for future drug development.…”
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18815
Alpinetin Attenuates Persistent Inflammation, Immune Suppression, and Catabolism Syndrome in a Septic Mouse Model
Published 2021-01-01“…These findings suggested that alpinetin could be a potential novel therapeutic approach to prevent sepsis-induced PICS.…”
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18816
Color Stability and Surface Properties of PMMA/ZrO2 Nanocomposite Denture Base Material after Using Denture Cleanser
Published 2021-01-01“…Statement of Problem. Novel polymethyl methacrylate (PMMA) containing zirconium dioxide nanoparticles (nano-ZrO2) was suggested as a denture base material but there is a lack of information regarding denture cleanser effects. …”
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18817
Influence of Ni, Al, W doping on microstructure, corrosion and wear resistance of HVOF spraying Fe-based amorphous alloy coatings
Published 2025-03-01“…A series of novel Fe-based amorphous alloy coatings (AACs) with outstanding corrosion and wear resistance, composed of Fe57Cr15Mo4P10C7B3M4 (M = Fe, Ni, Al and W, in at. %) with various alloying elements, were fabricated using high-velocity oxygen fuel (HVOF) technique. …”
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18818
Iodine promoted one-pot synthesis of flavones
Published 2025-01-01“…A novel one-pot methodology for the synthesis of flavones starting from simple precursors such as 2′-hydroxyacetophenone and benzaldehyde derivatives in pentan-1-ol (a green solvent), without additives, mediated by iodine and with short reaction times (1 h) is described. …”
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18819
A three-dimensional mouse liver organoid platform for assessing EDCs metabolites simulating liver metabolism
Published 2025-01-01“…These results indicate that mLOs provides a novel biological method to screen for potential endocrine-disrupting activities of EDC metabolites.…”
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18820
Using microfluidic shear to assess transfusion requirements in trauma patients
Published 2024-05-01“…We hypothesize the CA and PCF from this novel assay will provide information that correlates with trauma-induced coagulopathy and transfusion requirements.Methods Blood samples were collected on adult trauma patients from a single-institution prospective cohort study of high-level activations. …”
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