What have we learnt from histology about the efficacy of coronary imaging modalities in assessing plaque composition? by Nathan Angelo Lecaros Yap, Zahid Khan, Zahid Khan, Xingwei He, Jae-Geun Lee, Soe Maung, Kimberley R. Morgan, Tingquan Zhou, Helle Precht, Patrick W. Serruys, Patrick W. Serruys, Hector M. Garcia-Garcia, Yoshinobu Onuma, Sean Hynes, Sebastian Kelle, Anthony Mathur, Anthony Mathur, Andreas Baumbach, Andreas Baumbach, Christos V. Bourantas, Christos V. Bourantas

“…This review aims to provide a comprehensive evaluation of the performance of intravascular imaging in characterizing plaque phenotypes using histology as a reference standard; it summarizes the studies comparing the available invasive imaging techniques against histology, discusses the findings and limitations of these studies and highlights the potential of novel intravascular imaging approaches that were introduced for a more complete and comprehensive evaluation of plaque pathobiology.…”
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Design and validation of a programmable dual-tunnel soft pneumatic origami actuator with a large maximum shrinkage rate for reciprocating motion by R. Xu, R. Xu, R. Xu, Q. Meng, Q. Meng, Q. Meng, Q. Xie, Q. Xie, Q. Xie, Y. Zheng, Y. Zheng, Y. Zheng, C. Fei, C. Fei, C. Fei, V. Parenti Castelli, H. Yu, H. Yu, H. Yu

“…This paper presents a novel dual-tunnel soft pneumatic origami actuator capable of providing a large maximum shrinkage rate for reciprocating motion. …”
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Proactive and Integrated Management and Empowerment in Parkinson’s Disease: Designing a New Model of Care by Emma Tenison, Agnes Smink, Sabi Redwood, Sirwan Darweesh, Hazel Cottle, Angelika van Halteren, Pieter van den Haak, Ruth Hamlin, Jan Ypinga, Bastiaan R. Bloem, Yoav Ben-Shlomo, Marten Munneke, Emily Henderson

“…A multidisciplinary team of professionals in the United Kingdom and the Netherlands, all with a long history of caring for patients with movement disorders, used knowledge of deficiencies with the current model of care, an understanding of integrated care in chronic disease and the process of logic modelling, to develop a novel approach to the care of patients with Parkinson’s disease. …”
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Capital structure, profitability, and short-term solvency of nascent SMEs in Ghana: An empirical study by Karikari Amoa-Gyarteng, Shepherd Dhliwayo

“…ORIGINALITY AND VALUE: The study’s conceptualization that capital structure and profitability relate significantly to short-term solvency and, therefore, buffers the liability of newness is novel. Second, by showing that the trade-off theory’s tenets are relevant to the short-term solvency of nascent SMEs, the study demonstrates that capital structure theories apply equally to SMEs, just as much as large firms…”
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Utilizing kombucha culture for coffee fermentation and biochemical characteristic analysis by Hayeong Kim, Jihyeon Jeon, Jiyeon Lee, Chaeri Song, Boncheol Gu, Nahyun Mariah Kim, Tae-hui Yang, Sejin Oh, Soochul Park, Kunal Pal, Ghahyun Jeffrey Kim, Doman Kim

“…These results support the feasibility of kombucha fermentation as a novel approach to develop specialty coffees with enhanced flavour and nutritional profiles.…”
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Therapeutic effect of low-dose BMSCs-Loaded 3D microscaffold on early osteonecrosis of the femoral head by Minzheng Guo, Baochuang Qi, Zijie Pei, Haonan Ni, Junxiao Ren, Huan Luo, Hongxin Shi, Chen Meng, Yang Yu, Zhifang Tang, Yongqing Xu, Qingyun Xue, Chuan Li

“…In this study, we employed a novel cell carrier material termed ''3D Microscaffold'' to deliver BMSCs, addressing these issues and enhancing the therapeutic effects of cell therapy for ONFH. …”
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MSC-EXs inhibits uranium nephrotoxicity by competitively binding key proteins and inhibiting ROS production by Xinrui Yang, Jing Liu, Yaru Yin, Luxun Yang, Mingquan Gao, Zifei Wu, Binghui Lu, Shenglin Luo, Weidong Wang, Rong Li

“…This study identifies MSC-EXs as a novel therapeutic strategy against depleted uranium poisoning, presenting potential advancements in treatment methodologies.…”
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Nutritional and antioxidative characterization, antimicrobial and sensorial stability of flaxseed powder supplemented mutton patties by Raheel Suleman, Hira Choudhary, Muhammad Waseem, Jaza Maqbl Alshammari, Muhammad Muzamil, Huan Liu, Tariq Ismail, Muhammad Ammar Khan, Muhammad Qamar, Crossby Osei Tutu

“…Conclusively, owing to better potential of FP in improving the nutritional and microbial quality of mutton patties, the study further suggests its ability to act as a novel functional ingredient of choice in shelf-life extension of other food products.…”
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Towards a better understanding of biofoams: Multi-technique characterization of various tannin-furanic foams to assist in material selection for product design by Thomas Sepperer, Giulia Saccomano, Diana E. Bedolla, Raphael J.F. Berger, Primoz Šket, Elena Longo, Gregor A. Zickler, Saeed Borhani, Diego Dreossi, Lisa Vaccari, Maurizio E. Musso, Francesco D’Amico

“…With the objective of developing novel foam production strategies, three different tannin-furanic foams, namely mechanical, sulfuric and nitric, were thoroughly chemically characterized, and their morphological and macroscopic properties were compared with those of commercial plastic foams made of polystyrene and of polyethylene terephthalate. …”
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Evaluating the potential of Kalanchoe pinnata, Piper amalago amalago, and other botanicals as economical insecticidal synergists against Anopheles gambiae by Sheena Francis, William Irvine, Lucy Mackenzie-Impoinvil, Lucrecia Vizcaino, Rodolphe Poupardin, Audrey Lenhart, Mark J. I. Paine, Rupika Delgoda

“…Conclusion This study demonstrates that extracts from P. amalago var. amalago and K. pinnata, with inhibitory properties, IC50 < 6.95 μg/ml, against recombinant anopheline CYPs may be developed as natural synergists against anopheline mosquitoes. Novel synergists can help to overcome metabolic resistance to insecticides, which is increasingly reported in malaria vectors. …”
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Assessment of relative energy deficiency in sport and malnutrition prevalence in female endurance runners by energy availability questionnaire, bioelectrical impedance analysis and... by Samantha Sharp, Roni Mashiach-Fransis, Nicola Keay, Adrian Slee

“…BIA indicators of malnutrition, including FFMI, FMI, PA, may function as useful and novel clinical indicators of REDs in female runners. …”
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Genetic insights into MIS-C Post-COVID-19 in Kuwaiti children: investigating monogenic factors by Mohammed Dashti, Hessa AlKandari, Hessa AlKandari, Md Zubbair Malik, Rasheeba Nizam, Sumi Elsa John, Sindhu Jacob, Arshad Channanath, Fouzeyah Othman, Safa Al-Sayed, Osama Al-Hindi, Mona Al-Mutari, Thangavel Alphonse Thanaraj, Fahd Al-Mulla

“…The candidate variants approach identified 33 rare, predicted deleterious heterozygous variants across 19 unique genes in 19 of the 24 probands, including both previously described and novel candidate variants for MIS-C. Pathway analysis of the identified genes from both approaches revealed significant involvement in immune response, viral defence, and inflammatory pathways.ConclusionThis study underscores the monogenic susceptibility to MIS-C, enhancing the evidence base through comprehensive genetic analysis. …”
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Diagnosis and genomic characterization of the largest western equine encephalitis virus outbreak in Uruguay during 2023–2024 by Gonzalo Tomás, Ana Marandino, Sirley Rodríguez, Gabriel Luz Wallau, Filipe Zimmer Dezordi, André Luiz Sá de Oliveira, Claudia Techera, Lucía Calleros, Sofía Grecco, Joaquín Williman, Ramiro Pérez, Lucía Bassetti, Raúl Negro, Lucía Moreira Marrero, Adriana Delfraro, Roberto Vidal, Yanina Panzera, Ruben Pérez

“…We obtained genomes from 15 strains using a novel multiplex PCR assay combined with next-generation Illumina sequencing. …”
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Serum-derived small extracellular vesicles as biomarkers for predicting pregnancy and delivery on assisted reproductive technology in patients with endometriosis by Ayako Muraoka, Akira Yokoi, Akira Yokoi, Akira Yokoi, Kosuke Yoshida, Kosuke Yoshida, Masami Kitagawa, Bayasula, Mayuko Murakami, Natsuki Miyake, Reina Sonehara, Tomoko Nakamura, Satoko Osuka, Hiroaki Kajiyama

“…Although no predictors were found from miRNAs in serum EVs without endometriosis, miRNAs in serum EVs of patients with endometriosis could provide novel noninvasive biomarkers to predict pregnancy and have potential clinical applicability in ART.DiscussionFurther studies are required to examine the functional importance of these miRNAs to elucidate the pathological mechanisms of endometriosis and pregnancy.…”
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Chain-type multi-mode polarization-sensitive metamaterial absorber in infrared band by Xinyu Wang, Zhongzhu Liang, Fuming Yang, Xiaoyan Shi, Jinhuan Li, Yongjun Dong, Weizhen Liu, Yan Jia, Wenwen Sun, Zhe Wu, Xiangtao Chen, Siyu Guo

“…Despite the challenges in achieving broadband polarization-sensitive absorption in both the mid-infrared and long-wave infrared spectrums, this paper introduces a novel multi-mode polarization-sensitive infrared metamaterial absorber designed with a chain-type structure. …”
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Biomechanical Modeling and Evaluation of Buttocks Automatic Assisted Repositioning in Bedridden Patients by Liqing Yang, Ganjun Song, Di Luo, Haotian Xu, Jiamei Han, Mingzhao Xiao, Dingqun Bai, Shan Tian, Wensheng Hou, Jisi Tang, Xin Zhang, Lin Chen

“…Therefore, this study developed a novel computational model that integrates the buttocks with a support mattress to simulate automatic assisted repositioning, thereby analyzing deep tissue responses and optimizing tilt angles for effective load offloading. …”
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Chemopreventative potential of Salsola tuberculatiformis Botch and Compound A in the differential regulation of IL-1Ra:IL-1α in UVB exposed skin keratinocytes by T. Magcwebeba, L. McEvoy, S. Hayward, T. Tait, J.L Quanson, L. Kelbe, WCA Gelderblom, M. Lilly, A.C Swart, P. Swart

“…Compound A displayed a novel indirect anti-inflammatory effect by removing inflamed and damaged cells via apoptosis and ROS production. …”
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The Clinical Value of the Combined Detection of Systemic Immune-Inflammation Index (SII), Systemic Inflammation Response Index (SIRI), and Prognostic Nutritional Index (PNI) in Ear... by Zheng J, Zheng L, Wang X, Mao X, Wang Q, Yang Y, Mo D

“…The study delves into novel hematological inflammatory markers, such as systemic immune-inflammation index (SII), systemic inflammation response index (SIRI), and prognostic nutritional index (PNI), to explore their potential applications in early diagnosis of GC.Methods: From October 2020 and August 2024, 1339 GC patients admitted to our hospital were enrolled in this study. …”
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Training for Sustainable and Healthy Building for 2050: New Methodologies for an Integrated and Transnational Education Approach Targeting Skills Development for the Transition Tow... by Maria K. Koukou, Susana Lucas, Julia Justino, Silviano Rafael, Antonios D. Livieratos, Nelson Carriço, John Konstantaras, Michail Gr. Vrachopoulos, Anna Chiara Benedetti, Cecilia Mazzoli, Annarita Ferrante, Mohammad Abdollah Fadel Abdollah, Rossano Scoccia, Jacopo Famiglietti, Tomasz Bakoń, Joanna Aleksiejuk-Gawron

“…In responding to those challenges, the main objective of the research is to design, implement, and evaluate a novel, integrated, and transnational educational approach aimed at equipping professionals and students in the construction sector with the necessary skills to achieve sustainable and energy-efficient buildings. …”
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Isolation, purification, structural characteristic and antioxidative property of polysaccharides from A. cepa L. var. agrogatum Don by Hongcheng Liu, Hongxiu Fan, Jing Zhang, Shanshan Zhang, Wenting Zhao, Tingting Liu, Dawei Wang

“…Allium cepa L. var. agrogatum Don (ALAP) is commonly consumed in China as well as other regions and has various beneficial health effects. A novel acidic polysaccharide (named ALAP-21) was obtained from ALAP by ultrasonic and microwave-assisted extraction and purification using DEAE-52 anion exchange and Sephadex G-100 columns. …”
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