Clinical Characteristics of Asymptomatic Patients with SARS-CoV-2 in Zhejiang: An Imperceptible Source of Infection by Wei Dai, Xinmiao Chen, Xiaoting Xu, Zhefeng Leng, Wenwen Yu, Hui Lin, Huiying Li, Jie Lin, Zhangwei Qiu, Yuanrong Dai

“…Coronavirus disease 2019 (COVID-19), caused by the novel coronavirus SARS-CoV-2, was first identified in December 2019 in Wuhan, China, and has since spread globally, resulting in an ongoing pandemic. …”
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Utilisation of the Innovative [18F]-Labelled Radiotracer [18F]-BIBD-071 Within HR+ Breast Cancer Xenograft Mouse Models by Di Fan, Xin Wang, Xueyuan Ling, Hongbin Li, Lu Zhang, Wei Zheng, Zehui Wu, Lin Ai

“…The MCF-7 cell line, which is hormone receptor-positive (HR+), was used in the assessment of the novel [18F]-labelled radiotracer [18F]BIBD-071 via positron emission tomography (PET) imaging of an HR+ breast cancer xenograft model. …”
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Study on the antioxidant and antiosteoporotic activities of the oyster peptides prepared by ultrasound-assisted enzymatic hydrolysis by Zhengze Quan, Zonghan Wang, Zixu Wang, Zuoxu Hou, Bin Liu, Xiaoming Guo, Beiwei Zhu, Yuanyuan Hu

“…Importantly, TOPH-200 effectively enhanced osteogenic cell proliferation, differentiation, and mineralization in H2O2-treated MC3T3-E1 cells. Additionally, two novel peptides, DSQLAPFRF and HFNPRL, were screened from the TOPH-200 using PeptideRanker and molecular docking. …”
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Microinvasive interventions in the management of proximal caries lesions in primary and permanent teeth- systematic review and meta-analysis by Robina Tasleem, Saleh Ali Alqahtani, Naif Abogazalah, Hussain Almubarak, Ammara Riaz, Sarosh Sher Ali, Zeeshan Allana

“…Various interventions are available for the management, of which microinvasive techniques such as infiltration, sealants, glass ionomers, are novel and convenient. The purpose of this systematic review and meta-analysis was to compare microinvasive techniques with noninvasive or invasive treatment modalities in terms of effectiveness in halting interproximal caries lesion progression radiographically assessed. …”
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Genomic strategies to facilitate breeding for increased β-Glucan content in oat (Avena sativa L.) by Sumandeep Kaur Bazzer, Guilherme Oliveira, Jason D. Fiedler, Raja Sekhar Nandety, Jean-Luc Jannink, Melanie Caffe

“…The overall GWAS identified 73 loci, of which 15 coincided with loci identified for individual environments and 37 coincided with previously reported β-glucan QTLs not identified when performing the GWAS in single years. In addition, 21 novel loci were identified that were not reported in the previous studies. …”
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Innovative CO2-NBs-assisted ultrasonication for the phytochemical extraction of peanut (Arachis hypoga) shells: Synthesis and characterization of CO2-nanobubbles by Nayyar Iqbal, Miral Javed, Ramy M. Khoder, Areej Areej, Renyu Zheng, Shanbai Xiong, Ibrahim Khalifa, Hassan Barakat, Youming Liu

“…This study was designed to obtain the maximum extraction yield of peanut shell (PS) polyphenols using a novel carbon dioxide nanobubbles (CO2-NBs) assisted ultrasonic extraction method. …”
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STAT4, TRAF3IP2, IL10, and HCP5 Polymorphisms in Sjögren’s Syndrome: Association with Disease Susceptibility and Clinical Aspects by Serena Colafrancesco, Cinzia Ciccacci, Roberta Priori, Andrea Latini, Giovanna Picarelli, Francesca Arienzo, Giuseppe Novelli, Guido Valesini, Carlo Perricone, Paola Borgiani

“…We confirmed the association of SS with the STAT4 and IL10 genes and we describe a novel association with HCP5. In particular, we describe an association of this specific SNP of HCP5 not only with disease development but also with autoantibody production and focus score suggesting a potential contribution of this variant to a more severe phenotype.…”
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Exploring the metabolic dynamics, storage stability, and functional potential of Lacticaseibacillus rhamnosus Probio-M9-fermented milk by Xiaoye Liu, Kaiyang Liu, Jie Yang, Hui Qiao, Lai-Yu Kwok, Wenyi Zhang

“…Functional metabolites like syringaldehyde, leucic acid, and gentianose accumulated toward the end of fermentation, whereas peptides emerged as the main differential metabolites after the 28-d storage period. The study offers novel insights into the metabolic dynamics of Probio-M9 during fermentation and storage, which may inform the optimization of Probio-M9-fermented milk production processes. …”
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ANN-based two hidden layers computational procedure for analysis of heat transport dynamics in polymer-based trihybrid Carreau nanofluid flow over needle geometry by Adil Darvesh, Fethi Mohamed Maiz, Basma Souayeh, Luis Jaime Collantes Santisteban, Hakim AL. Garalleh, Afnan Al Agha, Lucerito Katherine Ortiz García, Nicole Anarella Sánchez-Miranda

“…This geometry facilitates the heat transfer mechanism, which could be crucial in many real-world applications such as cooling of electronic devices, heat exchangers and advanced manufacturing techniques. Purpose: A novel investigation of polymer-based trihybrid Carreau nanofluid flow subjected to thermal radiation and magnetohydrodynamic consequences (MHD) over a continuously moving thin needle has been made in this research attempt. …”
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Diagnostic value of the MZXBTCH scoring system for acute complex appendicitis by Tianyi Ma, Qian Zhang, Hongwei Zhao, Peng Zhang

“…Abstract The objective of this study was to develop a novel scoring model, assess its diagnostic value for complex appendicitis, and compare it with existing scoring systems. …”
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Subcytotoxic transepidermal delivery using low intensity cold atmospheric plasma by Ga Ram Ahn, Hyung-Joon Park, Yu Jin Kim, Min Gyo Song, Hye Sung Han, Woo Geon Lee, Hyuck Ki Hong, Kwang Ho Yoo, Joon Seok, Kyu Back Lee, Beom Joon Kim

“…Under our study conditions, LICAP treatment seems to be a novel approach to facilitate TED with low safety concerns in vitro. …”
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A Small-Area 2nd-Order Adder-Less Continuous-Time ΔΣ Modulator With Pulse Shaping FIR DAC for Magnetic Sensing by Manish Srivastava, Alessandro Ferro, Aleksandr Sidun, Jose M. De La Rosa, Kilian O'Donoghue, Padraig Cantillon-Murphy, Daniel O'Hare

“…A cascade of integrators in a feed-forward architecture implemented with an adder-less architecture has been proposed to minimise the silicon area. In addition, a novel continuous-time pulse-shaped digital-to-analog converter (CT-PS DAC) is proposed for excess loop delay (ELD) compensation to simplify the current drive requirements of the reference voltage buffer. …”
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Strain rebound and inhomogeneity in glass-to-metal seals: Radial vs axial strain evolution by Keqian Gong, Zheng Liu, Zifeng Song, Chao Zhou, Zhangjing Shi, Siyue Nie, Weisong Zhou, He Yan, Zhichun Fan, Yong Zhang

“…This study employs advanced fiber Bragg grating (FBG) in situ monitoring to decouple and independently analyze radial and axial strain evolution, providing novel insights into the mechanical anisotropy of sealing glass. …”
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In situ detection of piRNA‐651 in exosomes and cells for cancer diagnosis by a new gold nanoparticle nucleic acid probe by Qin‐Xin Gao, Qian‐Qian Wu, Zhi‐Ying Dong, Xiao‐Yuan Qin, Lin‐Yan Zhai, Bao‐Ping Xie, Wen‐Jun Duan

“…Abstract Increasing studies have demonstrated that PIWI‐interacting RNAs (piRNAs) in circulating exosomes can serve as novel molecular biomarkers for tumor liquid biopsy. …”
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Fiber length distribution characterizes the brain network maturation during early school-age by Yanlin Yu, Qing Cai, Longnian Lin, Chu-Chung Huang

“…This study proposes fiber length distribution as a novel nodal metric to capture the continuous maturation of brain network. …”
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Evaluation of exo-long noncoding RNA MALAT1 in OSCC in comparison to dysplastic and normal: A cross-sectional study by Ramya Sekar, Selvaraj Jayaraman, VishnuPriya Veeraraghavan, Kalaiselvi Krishnamoorthy, Shubhra Chauhan Aramanai, Sathan Raj Natarajan

“…Continued research into MALAT1's regulatory roles and its interactions within the tumor microenvironment holds promise for uncovering novel therapeutic targets and biomarkers that could redefine the management of OSCC in the future.…”
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Rnd3 protects against doxorubicin-induced cardiotoxicity through inhibition of PANoptosis in a Rock1/Drp1/mitochondrial fission-dependent manner by Wen Ge, Xiaohua Zhang, Jie Lin, Yangyang Wang, Xiao Zhang, Yu Duan, Xinchun Dai, Jiye Zhang, Yan Zhang, Mengyuan Jiang, Huanhuan Qiang, Zhijing Zhao, Xuebin Zhang, Dongdong Sun

“…Our findings suggest that the Rnd3/Rock1/Drp1 signaling pathway represents a novel target for mitigating DIC, and modulating Rnd3 expression could be a strategic approach to safeguarding cardiac function in patients undergoing Dox treatment. …”
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Comparison of Suture Anchor Repair and Suture Tape Augmentation for Reconstruction of the Anterior Talofibular Ligament: A Biomechanical Study by Qingfeng Shao, Dahai Hu, Xinru Chen, Huajun Wang, Lei Xiao, Qiang Teng, Jinsong Hong, Huige Hou, Xiaofei Zheng

“…Conclusions In terms of failure load and stiffness, the reconstructive outcome of ATFL reconstruction with STA is markedly superior to that of SAR reconstruction of the ATFL and the intact ATFL. Additionally, the novel technique of the SAR was a reliable technique that offered biomechanical properties similar to intact ATFL.…”
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Disturbed shear stress promotes atherosclerosis through TRIM21‐regulated MAPK6 degradation and consequent endothelial inflammation by Feng Wang, Shu‐Yu Wang, Yue Gu, Shuai Luo, Ai‐Qun Chen, Chao‐Hua Kong, Wen‐Ying Zhou, Li‐Guo Wang, Zhi‐Mei Wang, Guang‐Feng Zuo, Xiao‐Fei Gao, Jun‐Jie Zhang, Shao‐Liang Chen

“…Conclusions Our study illuminates the advantages of MAPK6 in decelerating plaque progression, highlighting the potential of safeguarding MAPK6 as a novel therapeutic strategy against atherosclerosis. …”
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Lattice-based interpenetrating phase composite metamaterial fabricated with hybrid material extrusion process for tunable mechanical properties by Ritik Raj, Jung-Ting Tsai, Mayur Jiyalal Prajapati, Jeng-Ywan Jeng

“…This study introduces a novel hybrid material extrusion (MEX) technique to fabricate lattice-based IPC metamaterials. …”
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