A class imbalance aware hybrid model for accurate rice variety classification by Hanumesh Vaidya, K.V. Prasad, C. Rajashekhar, D Tripathi, Renuka S, Jyoti Shetty, Kumar Swamy, Shobha Y

“…To tackle this critical gap in rice classification, we introduce a novel hybrid model: the XGBoost Multi-Layer 33Perceptron (XGB-MLP). …”
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MyVivarium: A cloud-based lab animal colony management application with realtime ambient sensing by Robinson Vidva, Mir Abbas Raza, Jaswant Prabhakaran, Ayesha Sheikh, Alaina Sharp, Hayden Ott, Amelia Moore, Christopher Fleisher, Hailey Netherton, Evan Goldstein, Pothitos M. Pitychoutis, Tam V. Nguyen, Aaron Sathyanesan

“…Taken together, MyVivarium is a novel, open-source, cloud-based application template that provides a low-cost, simple, and efficient way to digitally manage research-animal colonies.…”
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Connotation, research status, and development directions of clean coal geology in China by Yuegang TANG, Shaoqing WANG, Xiaoshuai WANG, Xin GUO, Yafeng WANG, Liping XUE, Harold H. Schobert

“…In the next decade, important research and development directions will include the spatiotemporal distribution of clean coals; the green, intelligent, quality-based combined production of paragenetic and associated minerals like coal gas; clean coal gasification; coal-based novel materials; underground coal-to-chemicals, and ecological restoration. …”
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Machine learning reveals sex differences in distinguishing between conduct-disordered and neurotypical youth based on emotion processing dysfunction by Gregor Kohls, Erik M. Elster, Peter Tino, Graeme Fairchild, Christina Stadler, Arne Popma, Christine M. Freitag, Stephane A. De Brito, Kerstin Konrad, Ruth Pauli

“…The “differential threshold” hypothesis suggests greater emotion dysfunction in conduct-disordered girls than boys, but previous research using conventional statistical analyses has failed to support this hypothesis. Here, we used novel analytic techniques such as machine learning (ML) to uncover potentially sex-specific differences in emotion dysfunction among girls and boys with CD compared to their neurotypical peers. …”
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Effects of Limosilactobacillus reuteri on gastrointestinal microbiota, muscle fiber formation and meat quality of Sunit sheep by Ting Liu, Chenlei Wang, Mirco Corazzin, Taiwu Zhang, Maoqin Zhai, Yue Zhang, Qiaoge Zhang, Xin Zhao, Ye Jin, Lina Sun

“…In conclusion, supplementation with L. reuteri may affect muscle fiber characteristics, enhance intestinal health, and facilitate carbohydrate digestion of Sunit sheep. This study offers novel insights into the use of feed additives for improving meat quality.…”
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Evaluating Pericoronary Adipose Tissue Attenuation to Predict Cardiovascular Events by Takahiro Nishihara, MD, PhD, Toru Miyoshi, MD, PhD, Kentaro Ejiri, MD, PhD, Kazuhiro Osawa, MD, PhD, Soichiro Fuke, MD, PhD, Kousuke Seiyama, MD, Masayuki Doi, MD, PhD, Mitsutaka Nakashima, MD, PhD, Takashi Miki, MD, PhD, Shinsuke Yuasa, MD, PhD

“…Background: Pericoronary adipose tissue attenuation (PCATA) is a novel imaging biomarker of pericoronary inflammation associated with coronary artery disease. …”
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Combination of reverse shock index and simplified motor score as a strong discriminator of trauma outcomes by Meng-Yu Wu, Giou-Teng Yiang, Ding-Kuo Chien, Sy-Jou Chen, Chi-Ming Chu, Jui-Yuan Chung, Hon-Ping Ma, Mau-Roung Lin

“…Background The reverse shock index multiplied by simplified motor score (rSI-sMS) is a novel and rapid measure for assessing injury severity in patients with trauma in prehospital settings; however, its discriminant ability requires further validation.Methods A retrospective cohort study was conducted from trauma database of Taipei Tzu Chi Hospital to compare the accuracy of the rSI-sMS with that of the shock index, modified shock index, reverse shock index multiplied by the Glasgow Coma Scale (rSI-GCS), and the reverse shock index multiplied by GCS motor subscale (rSI-GCSM) for discriminating in-hospital mortality, intensive care unit (ICU) admissions, prolonged ICU stays ≥14 days, and prolonged hospital stays ≥30 days in patients with trauma.Results A total of 11,760 patients from the trauma database were included. rSI-sMS had significantly better accuracy in discriminating in-hospital mortality, ICU admissions, prolonged ICU stays (≥14 days), and prolonged hospital stays (≥30 days) than the shock index, modified shock index, and rSI-GCSM, whereas its accuracy was similar to that of the rSI-GCS. …”
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Stature estimation and sex determination from contemporary Northeastern Thai clavicles using discriminant function and linear regression analyses by Chanasorn Poodendaen, Poonikha Namwongsakool, Sitthichai Iamsaard, Nareelak Tangsrisakda, Rarinthron Samrid, Chadaporn Chaimontri, Worrawit Boonthai, Suthat Duangchit

“…Conclusion: Multi-variable discriminant functions provide more reliability in sex determination while the combined-sex equations is the most effective method to estimate stature for contemporary Northeastern Thais. This novel method can be used to apply in the forensic anthropological analysis for Thai clavicle remain.…”
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Determination of distance away and depth of transmitters relative to a vertical acoustic telemetry array in the open ocean by Eric V. C. Schneider, Brendan S. Talwar, David M. Bailey, Shaun S. Killen, Dale M. Webber, Courtney E. MacSween, Travis E. Van Leeuwen, Frank I. Smith

“…Results Herein, we detail the development of a novel vertical acoustic telemetry array that can be mounted on, or suspended from, various moored and free-floating structures in the open ocean, thus facilitating high resolution tracking of structure-associated epipelagic animals. …”
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Preoperative liquid biopsy transcriptomic panel for risk assessment of lymph node metastasis in T1 gastric cancer by Ping’an Ding, Jiaxiang Wu, Haotian Wu, Wenqian Ma, Tongkun Li, Peigang Yang, Honghai Guo, Yuan Tian, Jiaxuan Yang, Limian Er, Renjun Gu, Lilong Zhang, Ning Meng, Xiaolong Li, Zhenjiang Guo, Lingjiao Meng, Qun Zhao

“…Conclusions We developed and validated a novel liquid biopsy-based RSA model that accurately predicts LNM in T1 GC patients. …”
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Integrative Bioinformatics Analysis to Identify Key Ferroptosis-Related Genes and Immune Infiltration in Aortic Aneurysm and Dissection: Implication of PTGS2 by An W, Luo J, Zhang C, Xiao Q

“…Functional studies also suggest a functional role of PTGS2 in ferroptosis and AAD development, offering novel insights into pathogenesis of human AAD.Keywords: aortic aneurysm and dissection, PTGS2, macrophage, ferroptosis, integrative bioinformatics analysis…”
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Spatial profiling of endoplasmic reticulum stress markers in tumor associated cells predicts patient outcomes in pancreatic cancer by Georgia Porter, Murray D. Norris, Minoti Apte, Angelica M. Merlot

“…The correlation of high ER stress in immune cells with poor patient survival highlights the importance of the TME and the use of spatial analysis for the identification of novel biomarkers.…”
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Glucose‐induced LINC01419 reprograms the glycolytic pathway by recruiting YBX1 to enhance PDK1 mRNA stability in hepatocellular carcinoma by Yanfang Liu, Junjiao Song, Qili Shi, Bing Chen, Wenying Qiu, Yizhe Liu, Shenglin Huang, Xianghuo He

“…Abstract Metabolic reprogramming provides the necessary energy for the development of malignant tumours and is emerging as a novel tumour treatment strategy. However, the widespread expression of metabolic enzymes in diverse cell types makes the development of specific drugs that target cancer cells without affecting normal cellular functions challenging. …”
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Generation of a genetically engineered porcine melanoma model featuring oncogenic control through conditional Cre recombination by Dongjin Oh, Nayoung Hong, Kiyoung Eun, Joohyeong Lee, Lian Cai, Mirae Kim, Hyerin Choi, Ali Jawad, Jaehyung Ham, Min Gi Park, Bohye Kim, Sang Chul Lee, Changjong Moon, Hyunggee Kim, Sang-Hwan Hyun

“…This melanoma-inducing system, heritably transmitted to offspring, supports large-scale studies. The novel porcine model provides a valuable tool for elucidating melanoma development and metastasis mechanism, advancing translational medicine, and facilitating preclinical evaluation of new anticancer drugs.…”
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Application of ATR-FTIR spectroscopy and multivariate statistical analysis in cancer diagnosis by Ao Song, Wanli Yang, Jun Wang, Yisa Cai, Lizheng Cai, Nan Pang, Ruihua Yu, Zhikun Liu, Chao Yang, Feng Jiang

“…The current study aims to explore novel diagnostic approaches for lung cancer by employing attenuated total reflection-Fourier transform infrared (ATR-FTIR) spectroscopy in conjunction with multiple machine learning models. …”
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Stretchable plasmonic metasurfaces for deformation monitoring by Li Peiyang, Gao Kaikai, Ma Ruize, Pan Kai, Li Dong, Liu Feng, Li Peng, Gan Xuetao, Zhao Jianlin, Wen Dandan

“…These results pave the way for developing microdevices with novel capabilities based on flexible metamaterials.…”
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Short Report – Birth Weight is Not Associated With Cataracts or Pseudophakia – Results from the Gutenberg Health Study by Fieß A, Gißler S, Grabitz S, Wild PS, Lackner KJ, Beutel ME, Urschitz MS, Tüscher O, Münzel T, Schattenberg JM, Konstantinides SV, Pfeiffer N, Schuster AK

“…No association was found between low BW and pseudophakia or the frequency of cataract surgery within 5 years. The study reveals novel insights from a large population-based study specifically exploring this association.Keywords: Cataract, pseudophakia, birth weight, epidemiology, population-based study…”
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The first application of flush probe arrays on HL-3 tokamak by Z.H. Huang, L.W. Yan, K.Y. Yi, Na Wu, W.J. Chen, W.C. Wang, Yu He, J. Chen, J. Cheng, W. Zhao, J.M. Gao, L. Nie, Z.B. Shi, X.Q. Ji, W.L. Zhong

“…It gradually increases with major radius. A novel design of ceramic isolation ring with a labyrinth can ensure reliable electrical insulation between the CFC tip and the divertor target plate where plasma dust and impurities are continuously deposited into their gaps due to long experimental operation. …”
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USC-Derived Small Extracellular Vesicles-Functionalized Scaffolds Promote Scarless Vaginal Defect Repair via Delivery of Decorin and DUSP3 Proteins by Xu Y, Li J, Qiu Y, Wu F, Xue Z, Liu B, Fan H, Zhou Y, Wu Q

“…This study highlights the potential of sEVs-loaded scaffolds as a promising strategy for scarless vaginal repair following vaginoplasty, offering a novel approach for regenerative medicine with significant translational potential for clinical application. …”
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Interneuron FGF13 regulates seizure susceptibility via a sodium channel-independent mechanism by Susan Lin, Aravind R Gade, Hong-Gang Wang, James E Niemeyer, Allison Galante, Isabella DiStefano, Patrick Towers, Jorge Nunez, Maiko Matsui, Theodore H Schwartz, Anjali Rajadhyaksha, Geoffrey S Pitt

“…To overcome these challenges, we generated a set of novel cell-type-specific conditional knockout mice. …”
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