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17981
Preoperative prediction of multiple biological characteristics in colorectal cancer using MRI and machine learning
Published 2025-01-01“…Alteration in molecular characteristic expression is closely related to tumor invasiveness and can serve a novel biomarker for predicting cancer prognosis. …”
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17982
Identification and validation of glucose metabolism-related gene signature in endometrial cancer
Published 2025-01-01“…Conclusions In this study, we developed six novel prognostic genes in EC based on glycolysis, and corresponding prognostic models were developed. …”
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17983
Structural and electronic features enabling delocalized charge-carriers in CuSbSe 2
Published 2025-01-01“…A limitation of these novel materials, which is being increasingly commonly found, is carrier localization, which substantially reduces mobilities and diffusion lengths. …”
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17984
Effects of a social participation-focused virtual reality intervention for community-dwelling stroke survivors with physical disabilities: a randomised controlled trial protocol
Published 2022-07-01“…The intervention group will receive a newly developed 6-week novel custom-made SP-VR application comprising two sessions weekly. …”
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17985
The first multiple center prospective study of rhFSH CTP in patients undergoing assisted reproductive technology in China
Published 2025-01-01“…Abstract We assessed the safety and efficacy of rhFSH-CTP, a novel long-acting FSH agent, in controlled ovarian hyperstimulation for patients undergoing ART. …”
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17986
Vector Field Heterogeneity for the Assessment of Locally Disorganised Cardiac Electrical Propagation Wavefronts From High-Density Multielectrodes
Published 2024-01-01“…These are often characterised by abnormal electrical conduction, which may cause locally disorganised propagation wavefronts. To quantify it, a novel heterogeneity parameter based on vector field analysis is proposed, utilising finite differences to measure direction changes between adjacent cliques. …”
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17987
Changes in the shape of the lumbar curve during growth: a geometric morphometric approach
Published 2025-01-01“…In this study, we used a novel method to estimate the shape of the lumbar curve (LC) using the landmark-based geometric morphometric method to explore changes in LC during growth, examine the effect of size and sex on LC shape, and examine the associations between angular measurements and shape. …”
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17988
DSMF-Net: Dual Semantic Metric Learning Fusion Network for Few-Shot Aerial Image Semantic Segmentation
Published 2025-01-01“…In this article, we propose to tackle these challenging problems via dual semantic metric learning and multisemantic features fusion and introduce a novel few-shot segmentation Network (DSMF-Net). On the one hand, we consider the inherent semantic gap between the feature of graph and grid structures and metric learning of few-shot segmentation. …”
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17989
Robust Band-Pass Filter-Based PLL-Less Approach for Three-Phase Nonsinusoidal Grid Conditions
Published 2024-01-01“…In order to remove even and odd-order harmonics and extract the fundamental frequency positive sequence (FFPS), the proposed method employs a combination of band pass filters (CBPFs). Additionally, a novel frequency estimation algorithm is developed, which accurately estimates the angular three-phase grid frequency. …”
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17990
A tale for two roles: Root-secreted methyl ferulate inhibits P. nicotianae and enriches the rhizosphere Bacillus against black shank disease in tobacco
Published 2025-01-01“…The great dual effect of methyl ferulate on the control of phytopathogens and its low cost enable a novel potential avenue for controlling soil-borne fungal diseases. …”
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17991
Phosphorylation of Arabidopsis NRT1.1 regulates plant stomatal aperture and drought resistance in low nitrate condition
Published 2025-01-01“…This finding identified a novel drought resistance mechanism enabled by post-transcriptional regulation of plasma membrane transporter.…”
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17992
An Experience of Jigsaw as a New Educational Method in Dentistry
Published 2024-11-01“…Background: Considering that simply relying on conventional education methods no longer suffices, educational systems have attempted to employ novel and active learning methods in their curriculum. …”
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17993
Biofilmed-PGPR: Next-Generation Bioinoculant for Plant Growth Promotion in Rice under Changing Climate
Published 2025-01-01“…We concluded that CBB could be used as a novel biofilm-based bio-inoculant to increase rice productivity and crop fitness as a component in integrated nutrient management and sustainable organic farming strategies with reduced chemical fertilizers.…”
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17994
Dissecting Causal Relationships Between Antihypertensive Drug, Gut Microbiota, and Type 2 Diabetes Mellitus and Its Complications: A Mendelian Randomization Study
Published 2025-01-01“…Colocalization supports these results (KCNJ11: 98% for diabetic retinopathy; SLC12A2: 99% for T2DM). Findings provide novel targets for the treatment of T2DM and its complications, emphasize the importance of KCNJ11 and SLC12A2 in future drug development, and highlight the significant mediating role of the genus Ruminococcus.…”
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17995
Unveiling new therapeutic horizons in rheumatoid arthritis: an In-depth exploration of circular RNAs derived from plasma exosomes
Published 2025-01-01“…This research screened differentially expressed circRNAs in RA patient plasma exosomes for novel diagnostic biomarkers. In this study, samples of RA patients with insufficient response to methotrexate (MTX-IR), combined use of tumor necrosis factor inhibitors (TNFi) were followed up for half a year, and 56 circRNA samples of self-test data were stratified into training, testing, and external validation cohorts according to whether American College of Rheumatology 20% improvement criteria (ACR20) was achieved. …”
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17996
Advanced Machine Learning to Predict Coronary Artery Disease Severity in Patients with Premature Myocardial Infarction
Published 2025-01-01“…Finally, an online calculator based on the XGBoost was established to measure the severity of coronary artery lesions in PMI patients Conclusions: In summary, we established a novel and convenient prediction system for the severity of lesions in PMI patients. …”
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17997
Elucidating stearoyl metabolism and NCOA4-mediated ferroptosis in gastric cancer liver metastasis through multi-omics single-cell integrative mendelian analysis: advancing personal...
Published 2025-01-01“…This investigation delves into the mechanisms underlying the intricate tumor microenvironment (TME) heterogeneity triggered by stearoyl metabolism in gastric cancer with liver metastasis (LMGC), offering novel perspectives for LMGC. Objective Utilizing Mendelian randomization, we determined that stearoyl metabolism significantly contributes to the progression of gastric cancer (GC). …”
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17998
Single-Cell RNA-Seq Uncovers Cellular Heterogeneity from Deep Fascia in Necrotizing Fasciitis Patients
Published 2025-01-01“…These proteins may act as a biomarker or even as a candidate therapy for NF.Conclusion: Our findings revealed the potential anti-infection role of deep fascia during the procession of NF, helping us understand the immunologic function of fascia and provide novel insights for its therapeutic strategies for NF.Keywords: necrotizing fasciitis, deep fascia, single-cell RNA-seq, M1/M2 polarization, fibroblast…”
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17999
Microbial keratitis in Southern Malawi: a microbiological pilot study
Published 2024-05-01“…We investigated the feasibility of using a novel corneal impression membrane (CIM) for obtaining and processing samples by culture, PCR and whole-genome sequencing (WGS) in patients presenting with suspected MK in Malawi.Methods and analysis Samples were collected from patients presenting with suspected MK using a 12 mm diameter polytetrafluoroethylene CIM disc. …”
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18000
Instructional design of smart technology use in teacher digital educational environment
Published 2023-11-01“…According to the provisions mentioned in Digital Kazakhstan Programme and Digital Teacher national project, the teacher today is regarded not just as an active user of the novel digital and smart technologies, but as the creator and transmitter of the authors’ digital educational content. …”
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