ORCHAMP: an observation network for monitoring biodiversity and ecosystem functioning across space and time in mountainous regions by Thuiller, Wilfried, Saillard, Amélie, Abdulhak, Sylvain, Augé, Vincent,  Birck, Carole, Bonet, Richard, Choler, Philippe, Delestrade, Anne,  Kunstler, Georges, Leccia, Marie-France, Lienard, Bertrand, Poulenard, Jérome, Valay, Jean-Gabriel, Bayle, Arthur, Bonfanti, Nicolas, Brousset, Lenka,  Bizard, Léa,  Calderón-Sanou, Irene, Dentant, Cédric, Desjonquères, Camille, Gielly, Ludovic, Guéguen, Maya, Guiter, Frédéric, Hedde, Mickael,  Hustache, Eric, Kedhim, Norine, Lapenu, Pierre, Le Guillarme, Nicolas,  Marchal, Lise, Mahieu, Chloé, Martin, Gabrielle, Martinez-Almoyna, Camille,  Miele, Vincent, Murienne, Jérôme, Paillet, Yoan, Rome, Maxime,  Renaud, Julien, The Orchamp Consortium

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Large-scale production of Mansonella perstans infective larvae from engorged Culicoides milnei by Chi Anizette Kien, Chi Anizette Kien, Rene Ebai, Rene Ebai, Fanny Fri Fombad, Fanny Fri Fombad, Frederick Esofi, Frederick Esofi, Anna Ning Ntuh, Anna Ning Ntuh, Emmanuel Ouam, Emmanuel Ouam, Narcisse Victor Tchamatchoua Gandjui, Narcisse Victor Tchamatchoua Gandjui, Valerine Chawa Chunda, Valerine Chawa Chunda, Relindis Ekanya, Relindis Ekanya, Franck Noel Nietcho, Franck Noel Nietcho, Juluis Visnel Foyet, Juluis Visnel Foyet, Lucy Cho Nchang, Lucy Cho Nchang, Chefor Magha, Chefor Magha, Abdel Jelil Njouendou, Abdel Jelil Njouendou, Peter Enyong, Peter Enyong, Achim Hoerauf, Achim Hoerauf, Achim Hoerauf, Manuel Ritter, Manuel Ritter, Samuel Wanji, Samuel Wanji

“…However, research about novel drugs against this filarial nematode is missing because of the lack of parasite material. …”
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Advances in CAR T cell therapy: antigen selection, modifications, and current trials for solid tumors by Safwaan H. Khan, Safwaan H. Khan, Yeonjoo Choi, Mysore Veena, Mysore Veena, John K. Lee, John K. Lee, Daniel Sanghoon Shin, Daniel Sanghoon Shin

“…Furthermore, we highlight key structural innovations, including cytokine-armored CARs, protease-regulated CARs, and CARs engineered with chemokine receptors, to enhance tumor infiltration and activity within the immunosuppressive microenvironment. Additionally, novel manufacturing approaches, such as the Sleeping Beauty transposon system, mRNA-based CAR transfection, and in vivo CAR T cell production, are discussed as scalable solution to improve the accessibility of CAR T cell therapies. …”
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Pathological and Molecular Characterization of Grass Carp Co-Infected with Two <i>Aeromonas</i> Species by Wenyao Lv, Zhijie Zhou, Lingli Xie, Xinyue Wang, Yifei Zhou, Lang Gui, Xiaoyan Xu, Yubang Shen, Jiale Li, Junqiang Qiu

“…These findings provide novel insights into the host–pathogen interactions during <i>Aeromonas</i> co-infection in grass carp, which may facilitate the development of effective prevention and control strategies.…”
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Development of a transportable High-Performance Liquid Chromatograph with Ultraviolet detection and a method for the rapid analysis of 13 carbonyl compounds hydrazones by Audrey Grandjean, Anaïs Becker, Mathilde Mascles, Franck Amiet, Jean-Philippe Amiet, Damien Bazin, Stéphane Le Calvé

“…This study proposes a simultaneous analysis of 13 carbonyl compounds, according to the ISO 16,000–3 reference method, adapted for a novel transportable High-Performance Liquid Chromatograph (HPLC) system. …”
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Integrating machine learning with mendelian randomization for unveiling causal gene networks in glioblastoma multiforme by Lixin Du, Pan Wang, Xiaoting Qiu, Zhigang Li, Jianlan Ma, Pengfei Chen

“…Conclusions This study demonstrates the power of combining machine learning and Mendelian Randomization to uncover novel genetic markers for GBM. The identified genes offer promising potential as biomarkers for GBM diagnosis and therapy, providing new avenues for personalized treatment strategies.…”
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CALPHAD-aided synthesis and characterization of an Al–Co–Cr–Fe–Ni–W high-entropy alloy prepared by arc melting and spark plasma sintering by L. Fenocchio, A. Saviot, S. Gambaro, S. Le Gallet, F. Valenza, M.R. Ardigo-Besnard, G. Cacciamani

“…In the present work, the novel Al0.15CoCrFeNiW0.15 High-Entropy Alloy (HEA) has been designed by CALPHAD (CALculation of PHAse Diagrams) computations with the in-house built Genova High-Entropy Alloys (GHEA) database, aiming to a mostly monophasic face-centered cubic (FCC) alloy strengthened by the precipitation of secondary μ phase. …”
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Stock price prediction with attentive temporal convolution-based generative adversarial network by Ying Liu, Xiaohua Huang, Liwei Xiong, Ruyu Chang, Wenjing Wang, Long Chen

“…To address this issue, we propose a novel stock price prediction method based on the Generative Adversarial Networks (GANs) framework, utilizing an Attentive Temporal Convolutional Network (ATCN) as the generator, termed Attentive Temporal Convolution-based Generative Adversarial Network (ATCGAN). …”
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Exosomes from Human Gingiva-Derived Mesenchymal Stem Cells Combined with Biodegradable Chitin Conduits Promote Rat Sciatic Nerve Regeneration by Feng Rao, Dianying Zhang, Tengjiaozi Fang, Changfeng Lu, Bo Wang, Xiao Ding, Shuai Wei, Yiran Zhang, Wei Pi, Hailin Xu, Yanhua Wang, Baoguo Jiang, Peixun Zhang

“…In summary, this study suggests that GMSC-derived exosomes combined with biodegradable chitin conduits are a useful and novel therapeutic intervention in peripheral nerve repair.…”
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Identification of natural compound inhibitors for substrate-binding site of MTHFD2 enzyme: Insights from structure-based drug design and biomolecular simulations by Nisarg Rana, Priyanka Solanki, Rukmankesh Mehra, Anu Manhas

“…By integrating multicomplex pharmacophore modeling, molecular dynamics, protein-ligand interaction energy analysis, and free energy calculations, this study offers a framework for identifying novel anticancer agents.…”
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qPRF: A system to accelerate population receptive field modeling by Sebastian Waz, Yalin Wang, Zhong-Lin Lu

“…The qPRF may facilitate the development and use of more elaborate models based on the PRF framework and may pave the way for novel clinical applications.…”
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The Role of Pentacyclic Triterpenoids in Non-Small Cell Lung Cancer: The Mechanisms of Action and Therapeutic Potential by Young-Shin Lee, Ryuk Jun Kwon, Hye Sun Lee, Jae Heun Chung, Yun Seong Kim, Han-Sol Jeong, Su-Jung Park, Seung Yeon Lee, Taehwa Kim, Seong Hoon Yoon

“…This underscores the growing need for novel therapeutic strategies to complement existing treatments and improve patient outcomes. …”
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Fluid structure Interaction analysis for rupture risk assessment in patients with middle cerebral artery aneurysms by Jozsef Nagy, Wolfgang Fenz, Stefan Thumfart, Julia Maier, Zoltan Major, Harald Stefanits, Maria Gollwitzer, Johannes Oberndorfer, Nico Stroh, Michael Giretzlehner, Michael Sonnberger, Andreas Gruber, Philip-Rudolf Rauch, Matthias Gmeiner

“…We also introduce the HGD index, a novel composite metric combining HESA, GLN, and Maximum Wall Displacement, designed to enhance predictive accuracy. …”
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Identification and verification of autophagy-related gene signatures and their association with immune infiltration and drug responsiveness in epilepsy by Han-han He, Xiao-ge Zhang, Fen-fang Chen

“…PIK3R1 expression level was found to be related with carbamazepine resistance.ConclusionThis study elucidated the autophagy-related gene signatures in epilepsy and clarified their association with immune infiltration and anti-epileptic drug responsiveness, providing a novel target for future therapeutic interventions and disease markers in epilepsy.…”
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Portable X-ray fluorescence of zinc and selenium with nail clippings-Mother and Infant Nutrition Investigation (MINI). by David E B Fleming, Nelly Madani, Michaela G Kaiser, Jong Sung Kim, Erin Keltie, Natashia Drage, Ying Jin, Jane Coad, Louise Brough

“…This work investigates a novel portable X-ray fluorescence (XRF) method with the ability to rapidly assess zinc and selenium in nail clippings. …”
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Dietary Supplementation with Inulin Modulates the Gut Microbiota and Improves Insulin Sensitivity in Prediabetes by Xiaojing Wang, Tong Wang, Qian Zhang, Li Xu, Xinhua Xiao

“…These findings suggest that insulin may be a potentially novel and inexpensive intervention for prediabetes.…”
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Multiomics approach identifies dysregulated lipidomic and proteomic networks in Parkinson’s disease patients mutated in TMEM175 by Federica Carrillo, Marco Ghirimoldi, Giorgio Fortunato, Nicole Piera Palomba, Laura Ianiro, Veronica De Giorgis, Shahzaib Khoso, Tiziana Giloni, Sara Pietracupa, Nicola Modugno, Elettra Barberis, Marcello Manfredi, Teresa Esposito

“…Altogether, these data provide novel insights into the molecular and metabolic alterations underlying TMEM175 mutations and may be relevant for PD prediction, diagnosis and treatment.…”
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Unique Case Reports Associated with Ovarian Failure: Necessity of Two Intact X Chromosomes by Lakshmi Rao Kandukuri, Venkata Padmalatha, Murthy Kanakavalli, Raseswari Turlapati, Mangalipally Swapna, Metuku Vidyadhari, Govindaraghavan Saranaya, Kattera Himaja, Mamata Deenadayal, Bipin Kumar Sethi, Prasun Deb, Nalini Gupta, Baidyanath Chakraborthy, Pratibha Nallari, Lalji Singh

“…Interestingly, majority of the abnormalities involved the X-chromosome and we report two unique abnormalities, (46,XXdel(Xq21-22) and q28) and (mos,45XO/46,X+ringX) involving X chromosome in association with ovarian failure. This study revealed novel X chromosome abnormalities associated with ovarian defects and these observations would be helpful in genetic counseling and apart from, infertility clinics using the information to decide suitable strategies to help such patients.…”
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Generalizing the Brady-Yong Algorithm: Efficient Fast Hough Transform for Arbitrary Image Sizes by Danil D. Kazimirov, Ekaterina O. Rybakova, Vitalii V. Gulevskii, Arseniy P. Terekhin, Elena E. Limonova, Dmitry P. Nikolaev

“…In this paper, we proposed 5 novel algorithms that incorporate the core idea of the Brady-Yong algorithm and are suitable for computing the fast HT for images of arbitrary size. …”
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Atherogenic index of plasma and coronary artery disease: a systematic review and meta-analysis of observational studies by Ramin Assempoor, Mohammad Shahabaddin Daneshvar, Aryan Taghvaei, Alireza Sattari Abroy, Amir Azimi, John R. Nelson, Kaveh Hosseini

“…Abstract Background Atherogenic index of plasma (AIP), a novel logarithmic index that combines fasting triglyceride and high-density lipoprotein cholesterol concentrations, is associated with the burden of atherosclerosis. …”
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