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17581
Microscopic Analysis of Temperature Effects on Surface Colonization and Biofilm Morphology of <i>Salmonella enterica</i>
Published 2025-01-01“…We developed methods using scanning electron microscopy and confocal microscopy with a novel image analysis software tool to investigate the temperature influence on <i>S. enterica</i> cell colonization and biofilm formation by directly visualizing and comparing the biofilm matrix’s morphological differences under various temperatures. …”
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17582
Integrated information theory reveals the potential role of the posterior parietal cortex in sustaining conditioning responses in classical conditioning tasks
Published 2025-01-01“…By applying the core complex framework to investigate neural substrates of sustained behavior, we provide novel insights into the interaction of cortical networks during classical conditioning, offering promising directions for future research in associative learning and behavior.…”
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17583
Predicting the tumor microenvironment composition and immunotherapy response in non-small cell lung cancer from digital histopathology images
Published 2024-12-01“…Here, we introduce HistoTME, a novel weakly supervised deep learning approach to infer the tumor microenvironment (TME) composition directly from histopathology images of NSCLC patients. …”
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17584
Comprehensive Evaluation of Inflammatory Biomarkers in Cervical Cancer Treated with Chemoradiotherapy
Published 2025-01-01“…Among the emerging biomarkers, the pan-immune-inflammation value (PIV) has recently been introduced as a novel indicator representing both the immune response and the systemic inflammatory state. …”
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17585
LipBengal: Pioneering Bengali lip-reading dataset for pronunciation mapping through lip gesturesHugging Face
Published 2025-02-01“…Captured under diverse and uncontrolled conditions, LipBengal stands as the most extensive Bengali lip-reading dataset to date, designed to facilitate robust benchmarking and validation of novel deep learning architectures. Detailed annotations extend from phoneme- level classifications to full sentence constructions, providing a granular and comprehensive dataset. …”
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17586
Ribosomal proteins mediate non-canonical regulation of gut inflammatory signature by crop contaminant deoxynivalenol
Published 2025-01-01“…In this study, we elucidate a novel regulatory mechanism involving ribosomal proteins (RPs) RPL13A and RPS3, which mediate proinflammatory chemokine production in DON-exposed gut epithelial cells. …”
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17587
Bibliometric Analysis of Neuroinflammation and Postoperative Cognitive Dysfunction
Published 2025-01-01“…This bibliometric analysis aims to provide novel insights into the research trajectory, key research topics, and potential future development trends in the field of neuroinflammation‐induced POCD. …”
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17588
Experimental procedures, influencing parameters, and future prospects of geological sequestration of carbon dioxide
Published 2025-01-01“…In addition, ongoing and future research avenues are also discussed, which include the development of novel monitoring technologies, new possibilities for evaluating long-term storage impacts, and improvements to CO2 capture and conversion methods. …”
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17589
IMU Sensor-Based Worker Behavior Recognition and Construction of a Cyber–Physical System Environment
Published 2025-01-01“…Therefore, in this study, we developed a novel miniaturized IMU (inertial measurement unit) sensor that can be simultaneously attached to multiple body parts of construction workers (head, body, hands, and legs). …”
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17590
The endocannabinoid system’s genetic polymorphisms in sickle cell anemia patients
Published 2024-12-01“…Since activating the type 2 cannabinoid receptor (CB2) decreases RhoA activation, we suggest a novel approach to SCA priapism involving CB2.…”
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17591
Black Soldier Fly (<i>Hermetia illucens</i>) Larvae as a Protein Substitute in Adverse Food Reactions for Canine Dermatitis: Preliminary Results Among Patients
Published 2025-01-01“…We evaluated BSF larvae’s safety, tolerance, and effectiveness as a novel protein source in dogs with AFRs. Sixteen dogs, including eight healthy controls and eight diagnosed with AFRs, were fed a diet containing BSF larvae for four weeks. …”
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17592
Alteration in the Cytokine Secretion of Bone Marrow Stromal Cells from Patients with Chronic Myelomonocytic Leukemia Contribute to Impaired Hematopoietic Supportive Activity
Published 2018-01-01“…These results suggested that BMSCs may contribute to the pathogenesis of CMML by altering their cytokine secretion, which will shed light on the further investigation to develop novel therapeutic strategies for CMML patients.…”
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17593
Modeling and experimental validation of nanophotonics-enhanced solar membrane distillation technology for treating reverse osmosis brine
Published 2024-12-01“…Abstract A novel, cost-efficient Nanophotonic Enhanced Solar Membrane Distillation (NESMD) system, a solar-driven water desalination technology, was studied. …”
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17594
Nootkatone Derivative Nootkatone-(E)-2-iodobenzoyl hydrazone Promotes Megakaryocytic Differentiation in Erythroleukemia by Targeting JAK2 and Enhancing JAK2/STAT3 and PKCδ/MAPK Cro...
Published 2024-12-01“…In conclusion, N2 shows great promise as a differentiation therapy for erythroleukemia, offering a novel approach by targeting JAK2-mediated signaling pathways to induce megakaryocytic differentiation.…”
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17595
SPC25 upregulates CCND1 to promote the progression of esophageal squamous cell carcinoma by inhibiting MDM2-mediated E2F1 ubiquitination
Published 2025-03-01“…These findings propose novel insights into the role of SPC25 in ESCC and provide potential therapeutic strategies for targeting SPC25 in ESCC patients.…”
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17596
Bioactivity and metabolic profiling of crude extracts from endophytic bacteria linked to Solanum mauritianum scope: Discovery of antibacterial and anticancer properties
Published 2025-01-01“…Bacterial endophytes associated with Solanum mauritianum Scop. represent a promising source of novel bioactive compounds with potential antibacterial and anticancer properties. …”
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17597
Identification of prognostic biomarkers of sepsis and construction of ceRNA regulatory networks
Published 2025-01-01“…GSPT1 and NPRL3 were lowly expressed in the sepsis Survivor group, compared with Non-survivor group, which may become novel prognostic biomarkers for sepsis. A sepsis-related ceRNA networks, which consists of 4 circRNA, 26 miRNA, and 2 core gene, may guide mechanistic studies.…”
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17598
Regulatory role of S1P and its receptors in sepsis-induced liver injury
Published 2025-01-01“…By elucidating the role of S1P and its receptor in the pathogenesis of sepsis liver injury, this review established a molecular targeting framework, providing novel insights into clinical and drug development.…”
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17599
Comprehensive analysis of ESCRT transcriptome-associated signatures and identification of the regulatory role of LMO7-AS1 in osteosarcoma
Published 2025-01-01“…In conclusion, our ESCRT transcriptome-associated signatures can act as prognostic biomarkers for OS, and LMO7-AS1 is a novel therapeutic target for the treatment of OS.…”
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17600
Community credit scores and community socioeconomic deprivation in association with type 2 diabetes across an urban to rural spectrum in Pennsylvania: a case–control study
Published 2024-04-01“…Stratified models assessing independent effects of CCS and CSD showed mainly consistent associations, indicating each community-level measure was independently associated with T2D.Conclusion CCS may capture novel, health-salient aspects of community socioeconomic conditions, though questions remain regarding the mechanisms by which it influences T2D and how these differ from CSD.…”
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