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17561
Advanced Path Planning for UAV Swarms in Smart City Disaster Scenarios Using Hybrid Metaheuristic Algorithms
Published 2025-01-01“…This paper presents a novel hybrid path planning approach combining affinity propagation clustering (APC) with genetic algorithms (GA), aimed at maximizing coverage, and ensuring quality of service (QoS) compliance across diverse environmental conditions. …”
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17562
Synthesis and evaluation of nitrochromene derivatives as potential antileishmanial therapeutics through biological and computational studies
Published 2025-01-01“…This study endeavors to address this critical need by focusing on the design and synthesis of a series of novel compounds. Fifteen derivatives incorporating the nitrochromene pharmacophore were meticulously synthesized using the Henry reaction. …”
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17563
Synthesis, characterization, In silico, and In vitro studies of CuS–ZnO nanocomposite using mushroom extract
Published 2025-03-01“…These biological activities relationship of experimental data's were evaluated through the novel computational tool of In Silico approach. It is essential to identify thread of emerging diseases. …”
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17564
Molecular Mechanisms Underlying Substance Transport, Signal Transduction, and Anti-Stress Regulation, as Well as Anti-Alkaline Regulation via <i>Bursicon</i> in the Cerebral Gangli...
Published 2025-01-01“…Furthermore, it was discovered for the first time that <i>bursicon</i> plays a positive regulatory role in the adaptation of <i>E. sinensis</i> to alkalinity. (4) Conclusions: The present study elucidates the molecular regulatory pattern of the cerebral ganglion in <i>E. sinensis</i> under acute alkaline stress as well as revealing a novel role of <i>bursicon</i> in facilitating adaptation to alkalinity in <i>E. sinensis</i>, providing valuable theoretical insights into the molecular regulatory mechanisms underlying the responses of cerebral ganglia to saline–alkali environments. …”
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17565
Antibody response to Plasmodium vivax in the context of Epstein-Barr virus (EBV) co-infection: A 14-year follow-up study in the Amazon rainforest.
Published 2025-01-01“…The experimental approach focused on monitoring antibodies to the major blood-stage P. vivax vaccine candidate, the Duffy binding protein region II (DBPII-Sal1), including a novel engineered DBPII-based vaccine targeting conserved epitopes (DEKnull-2). …”
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17566
Hepatic Cerebroside Sulfotransferase Is Induced by PPARα Activation in Mice
Published 2012-01-01“…These results suggest that PPARα activation enhances hepatic sulfatide synthesis via CST induction and implicate CST as a novel PPARα target gene.…”
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17567
UAV rice panicle blast detection based on enhanced feature representation and optimized attention mechanism
Published 2025-02-01“…This study introduces ConvGAM, a novel semantic segmentation model leveraging the ConvNeXt-Large backbone network and the Global Attention Mechanism (GAM). …”
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17568
Metasurface higher-order poincaré sphere polarization detection clock
Published 2025-01-01“…We actualize this concept through a novel meta-device known as the metasurface photonics polarization clock, which offers an intuitive display of SoP using four distinct pointers. …”
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17569
Software-Defined Value Stream Process Systems
Published 2025-01-01“…This paper introduces software-defined value stream process systems (SVPSs), a novel approach that extends the concept of software-defined manufacturing into autonomous, reconfigurable production systems. …”
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17570
Liquid-induced heat treatment strategy for eliminating anisotropy of IN718 fabricated by laser powder bed fusion
Published 2025-02-01“…However, the lack of driving force for recrystallization during the post-heat treatment within laser powder bed fusion (LPBF) makes this method inapplicable to the process. Here, we develop a novel liquid-induced heat treatment (LIHT) post-processing. …”
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17571
Temperature-dependent luminescence of europium-doped Ga₂O₃ ceramics
Published 2025-02-01“…While intrinsic Ga₂O₃ emission exhibits thermal quenching above 100 K, Eu³⁺-related emissions, notably the 611 nm red emission, show thermal stability, retaining ∼90 % of their intensity at 300 K. Additionally, a novel low-temperature emission peak at 1.74 eV, potentially associated with electron beam-induced defects, was detected, meriting further exploration. …”
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17572
Banxia Xiexin Decoction Ameliorates t-BHP-Induced Apoptosis in Pancreatic Beta Cells by Activating the PI3K/AKT/FOXO1 Signaling Pathway
Published 2020-01-01“…BXXD protected MIN6 cells against t-BHP-induced apoptosis and improved insulin secretory function through modulation of the PI3K/AKT pathway and the downstream FOXO1, thus suggesting a novel therapeutic approach for type 2 diabetes mellitus (T2DM).…”
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17573
Medialization of shaft of humerus to provide medial buttress and prevent varus collapse in 3- and 4-part proximal humerus fractures: review of the surgical technique
Published 2025-02-01“…Addressing this, we review a novel intraoperative technique of medialization of the humerus shaft to provide medial buttress support to the humerus head. …”
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17574
DLAT is involved in ovarian cancer progression by modulating lipid metabolism through the JAK2/STAT5A/SREBP1 signaling pathway
Published 2025-01-01“…Conclusion This study uncovers a novel DLAT/JAK2/STAT5/SREBP1 axis that reprograms lipid metabolism in OC, providing insights into metabolic vulnerabilities and potential therapeutic targets for OC treatment.…”
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17575
Anatomy-Informed Multimodal Learning for Myocardial Infarction Prediction
Published 2024-01-01“…In this work, we propose a novel anatomy-informed multimodal deep learning framework to predict future MI from clinical data and Invasive Coronary Angiography (ICA) images. …”
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17576
ADAMTS1, CRABP1, and NR3C1 Identified as Epigenetically Deregulated Genes in Colorectal Tumorigenesis
Published 2006-01-01“…In the present study, we aimed to identify and validate novel target genes inactivated through promoter hypermethylation in colorectal tumor development. …”
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17577
S100A8-CAMKK2-AMPK axis confers the protective effects of mild hypothermia against cerebral ischemia-reperfusion injury in rats
Published 2025-01-01“…By targeting the S100A8-initiated CAMKK2/AMPK signaling pathway, we may unlock a novel therapeutic intervention or develop a refined MH therapeutic strategy against cerebral IR injury.…”
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17578
A randomized comparative effectiveness trial to evaluate two programs for promotion of physical activity after spinal cord injury in manual wheelchair users
Published 2025-02-01“…ObjectiveThe goal of this study was to determine the effectiveness of a novel whole of day activity accumulation (WODAA) physical exercise program. …”
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17579
Driving brain state transitions via Adaptive Local Energy Control Model
Published 2025-02-01“…Network control theory offers a novel framework for investigating the dynamic characteristics of brain state transitions. …”
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17580
A Real-Time Human Pose Measurement System for Human-In-The-Loop Dynamic Simulators
Published 2025-01-01“…The system exploits pre-trained 2D human pose detection models and integrates an <inline-formula> <tex-math notation="LaTeX">$\alpha \text {-}\beta \text {-}\gamma $ </tex-math></inline-formula> filter to reduce fluctuations in detected key points. It also introduces a novel Weighted Direct Linear Triangulation method, enhancing 3D reconstruction accuracy by assigning higher weights to key points consistent across current and previous frames. …”
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