Introducing 3D printed models of fractures in osteology learning improves clinical reasoning skills among first-year medical students: a pilot study by Abhishek Agarwal, Anne D Souza, B. Jyostna, Ashwija Shetty, Nandini Bhat

“…Conclusion Incorporating 3D-printed models of fractures was a novel approach to help students comprehend the clinical correlations. …”
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Dual-stream disentangled model for microvascular extraction in five datasets from multiple OCTA instruments by Xiaoyang Hu, Xiaoyang Hu, Jinkui Hao, Quanyong Yi, Yitian Zhao, Jiong Zhang

“…These challenges typically results in less precise segmentation performance.MethodsTherefore, we propose a novel and robust Dual-stream Disentangled Network (D2Net) for retinal OCTA microvascular segmentation. …”
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A computational role of blood nanofluid induced by a stenosed artery with porous medium and thermophoretic particle deposition effects by Shivalila Hangaragi, N. Neelima, N. Beemkumar, Ankur Kulshreshta, Umair Khan, Noreen Sher Akbar, Mohammad Kanan, Mona Mahmoud

“…Deep learning models demonstrate significant efficacy in analyzing and predicting stenotic conditions. The novel outcomes of this research highlight the effectiveness of deep learning models in predicting and analyzing stenotic blood flow conditions, contributing to improved diagnostic approaches to improve the patient's healthcare and reduce the mortality rate.…”
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Effect of Exogenous Melatonin Administration in Critically Ill Patients on Delirium and Sleep: A Randomized Controlled Trial by Judith Bellapart, Vinesh Appadurai, Melissa Lassig-Smith, Janine Stuart, Christopher Zappala, Rob Boots

“…This study applies a previously published novel regimen of melatonin with proven sustained levels of melatonin during a 12 h period. …”
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Calcium Activation of the Androgen Receptor in Prostate Cells by Zeina W. Sharawi, Sawsan M. Khatrawi, Qiaochu Wang, Hongzhao Zhou, Kedra Cyrus, Gai Yan, Becky Hoxter, Bassem R. Haddad, Mary Beth Martin

“…Taken together, the results suggest a novel role of calcium in the castration-resistant phenotype.…”
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Gaussian process latent variable models-ANN based method for automatic features selection and dimensionality reduction for control of EMG-driven systems by Maham Nayab, Asim Waris, Muhammad Jawad Khan, Dokhyl AlQahtani, Ahmed Imran, Syed Omer Gilani, Umer Hameed Shah

“…To overcome such issues, this paper proposes a novel approach that integrates feature reduction techniques with an artificial neural network (ANN) classifier to enhance the accuracy of high-dimensional EMG classification. …”
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G-quadruplex-forming small RNA inhibits coronavirus and influenza A virus replication by Ryoya Sekine, Kouki Takeda, Tsukasa Suenaga, Satsuki Tsuno, Takumi Kaiya, Maki Kiso, Seiya Yamayoshi, Yoshihide Takaku, Shiho Ohno, Yoshiki Yamaguchi, Seiichi Nishizawa, Kazuhiro Sumitomo, Kazufumi Ikuta, Teru Kanda, Yoshihiro Kawaoka, Hidekazu Nishimura, Shusuke Kuge

“…Abstract Future pandemic threats may be caused by novel coronaviruses and influenza A viruses. Here we show that when directly added to a cell culture, 12mer guanine RNA (G12) and its phosphorothioate-linked derivatives (G12(S)), rapidly entered cytoplasm and suppressed the propagation of human coronaviruses and influenza A viruses to between 1/100 and nearly 1/1000 of normal virus infectivity without cellular toxicity and induction of innate immunity. …”
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Unlocking the therapeutic mechanism of Caesalpinia sappan: a comprehensive review of its antioxidant and anti-cancer properties, ethnopharmacology, and phytochemistry by Estéfani Alves Asevedo, Estéfani Alves Asevedo, Livia Ramos Santiago, Livia Ramos Santiago, Hyo Jeong Kim, Rony Abdi Syahputra, Moon Nyeo Park, Rosy Iara Maciel Azambuja Ribeiro, Bonglee Kim

“…Herbal medicine are an invaluable reservoir of bioactive compounds, offering immense potential for novel drug development to address a wide range of diseases. …”
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Fast-Read Storage Performance by Thyristor Operation in 3-D Flash Memory by Tomoya Sanuki, Hideto Horii, Takashi Maeda

“…., 2020), we have suggested novel WL bias conditions, referred to as the wide barrier mode, that can suppress the cell-to-cell interference effect. …”
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EZH2 Mediates miR-146a-5p/HIF-1α to Alleviate Inflammation and Glycolysis after Acute Spinal Cord Injury by Shuangfei Ni, Bo Yang, Lei Xia, Huafeng Zhang

“…Therefore, EZH2/miR-146a-5p/HIF-1α might be a novel potential target for treating ASCI.…”
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Indonesian Newcastle Disease Virus Field Isolate Reduces c-Jun Expression in Rat Mammary Cancer Models by Fransiska Gratia Sonita Marson, Palagan Senopati Sewoyo, I Nyoman Mantik Astawa, Anak Agung Ayu Mirah Adi, Ida Bagus Kade Suardana, Ida Bagus Oka Winaya, I Ketut Berata

“…This finding is considered novel, as there have been no previous reports of decreased c-Jun expression following virotherapy with NDV.…”
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Integrating artificial Intelligence-Based metaheuristic optimization with Machine learning to enhance Nanomaterial-Containing latent heat thermal energy storage systems by Ali Basem, Hanaa Kadhim Abdulaali, As’ad Alizadeh, Pradeep Kumar Singh, Komal Parashar, Ali E. Anqi, Husam Rajab, Pancham Cajla, H. Maleki

“…The present study proposes a novel strategy to provide optimal data-driven models for predicting the latent heat of NePCMs. …”
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Être étranger dans 'La Nouvelle Héloïse' by Nathalie Ferrand

“…Yet there are many ways to be foreign in La Nouvelle Héloïse, and this issue extends far beyond that of mere nationalities. This great novel is populated by a multitude of foreign figures who correspond closely to those encountered by the historian Simona Cerutti in the course of her research for her book Étrangers: étude d’une condition d’incertitude dans une société d’Ancien Régime. …”
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Lipidomic and Instrumental Evaluation of a Melatonin-Based In & Out Strategy Versus Topical Treatment in Skin Aging: A Randomized Prospective Trial by Francesca Colombo, Stefano Alfano, Massimo Milani

“…This study aimed to evaluate the efficacy of a novel “In & Out” strategy, combining topical and oral melatonin supplementation, in managing skin aging compared to topical treatment alone. …”
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Development of the pulmonary fibrosis, pulmonary vascular resistance, six minute walk distance, B-type natriuretic peptide, age (PVD-B65) risk score for patients with chronic lung... by Shameek Gayen, Jay Pescatore, Matthew Bittner, Mario Naranjo, Gerard J. Criner, Sheila Weaver, Temple Lung Center Pulmonary Vascular Disease Working Group

“…Conclusion The PVD-B65 risk assessment tool is a novel, internally validated one-year mortality risk calculator for patients with chronic lung disease and PH that encompasses factors related to pulmonary parenchymal and vascular remodeling. …”
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Magnetic field characterization of edge currents in quantum spin Hall insulators by Felipe A Pinto, Ricardo C Heitzer, Eitan Dvorquez, Roberto Rodriguez, Qiang Sun, Andrew D Greentree, Brant C Gibson, Jerónimo R Maze

“…This work provides insights that could be useful for the characterization of topological materials and the development of novel electro-optical devices.…”
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Deep Learning-Enabled Integration of Histology and Transcriptomics for Tissue Spatial Profile Analysis by Yongxin Ge, Jiake Leng, Ziyang Tang, Kanran Wang, Kaicheng U, Sophia Meixuan Zhang, Sen Han, Yiyan Zhang, Jinxi Xiang, Sen Yang, Xiang Liu, Yi Song, Xiyue Wang, Yuchen Li, Junhan Zhao

“…GIST provides a generalizable framework for integrating histology with spatial transcriptome analysis, revealing novel insights into spatial organization and functional dynamics.…”
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Finite-Time Output Robust Control for Restricted Joint Flight Emulator Robotic Arm With Adaptive Tangent Barrier Gains by Isaac Chairez, Alejandra Hernandez-Sanchez, Caridad Mireles, Arthur Mukhamedov, Grigory Bugriy, Stepan Lemak, Viktor Chertopolokhov

“…This research presents a novel, robust controller for acceleration tracking in robotic manipulators with time-varying joint limitations, accounting for articulation constraints. …”
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Prevalence of psychological distress: a scientific approach towards the mental health and wellbeing of population during the SARS-COV-2 outbreak [version 2; peer review: 2 approved... by Shazia Sadaf, Sara Noreen, Ahmed Alsubaie, Inayat Shah, Saman Tauqir, Saqib Ali

“…Background The global challenge of the novel coronavirus has led to an unprecedented downturn, adversely affecting the health and mental wellbeing of communities worldwide. …”
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Early Detection of Multiwavelength Blazar Variability by Hermann Stolte, Jonas Sinapius, Iftach Sadeh, Elisa Pueschel, Matthias Weidlich, David Berge

“…For this purpose, we have developed a novel deep learning analysis framework, based on data-driven anomaly detection techniques. …”
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