Genome-Wide Association Study of Liver Enzymes in Korean Children by Tae-Joon Park, Joo-Yeon Hwang, Min Jin Go, Hye-Ja Lee, Han Byul Jang, Youngshim Choi, Jae Heon Kang, Kyung Hee Park, Min-Gyu Choi, Jihyun Song, Bong-Jo Kim, Jong-Young Lee

“…We performed a genome-wide association study to identify new genetic loci for liver enzyme levels in a Korean childhood cohort (n = 484). We observed three novel loci (rs4949718, rs80311637, and rs596406) that were multiply associated with elevated levels of alanine transaminase and aspartate transaminase. …”
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Effects of message framing on self-management behaviour among patients with type 2 diabetes: a randomised controlled trial protocol by Xin Zhang, Feng Li, Hui Guo, Yue Pang, Yandi Liu, Ruitong Gao, Xiaoqian Lian, Tianyue Yu, Lanyu Zhu

“…However, with a rapid rise in the number of people with diabetes cases and the increasing burden on healthcare, it is often difficult for healthcare providers to find suitable time to provide health education to meet their needs. Thus, more novel and effective ways are needed to conduct education. …”
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Copper Super-Dosing Improves Performance of Heat-Stressed Broiler Chickens through Modulation of Expression of Proinflammatory Cytokine Genes by Sudipto Haldar, Amrita Kumar Dhara, Sayantani Sihi Arora, Arpana Verma Mukherjee, Arup Nayak

“…It was concluded from the present experiment that during conditions of impending HS, dietary supplementation of 112.5 to 150 mg Cu/kg diet as Cu-P may be a novel strategy to alleviate the negative effects of HS without involving any apparent risk of Cu toxicity.…”
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An Overview of Hybrid DC–DC Converters: From Seeds to Leaves by Yan Lu, Junwei Huang, Zhiguo Tong, Tingxu Hu, Wen-Liang Zeng, Mo Huang, Xiangyu Mao, Guigang Cai

“…Meanwhile, battery-powered portable or wearable devices favor extremely high-power-density solutions, calling for novel power conversion topologies, which have been the hottest topic in the power management IC area in the past decade. …”
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A Deep Learning for Optimization and Visualization of Expressway Toll Lane Management by Pattarapon Klaykul, Wilaiporn Lee, Kanabadee Srisomboon, Luepol Pipanmekaporn, Akara Prayote

“…This paper proposes a novel framework combining deep learning and multi-objective optimization to improve toll plaza efficiency. …”
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Hybrid parking space prediction model: integrating ARIMA, Long short-term memory (LSTM), and backpropagation neural network (BPNN) for smart city development by Anchal Dahiya, Pooja Mittal, Yogesh Kumar Sharma, Umesh Kumar Lilhore, Sarita Simaiya, Mohd Anul Haq, Mohammed A. Aleisa, Abdullah Alenizi

“…The present research mainly focuses on proposing a novel scalable hybrid model for accurately predicting parking space. …”
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stormTB: a web-based simulator of a murine minimal-PBPK model for anti-tuberculosis treatments by Roberto Visintainer, Anna Fochesato, Anna Fochesato, Daniele Boaretti, Stefano Giampiccolo, Stefano Giampiccolo, Shayne Watson, Micha Levi, Federico Reali, Luca Marchetti, Luca Marchetti

“…Various modeling efforts have emerged, offering tailored data-driven and physiologically-based solutions for novel and historical compounds. However, this diverse modeling panorama may lack consistency, limiting result comparability. …”
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Elucidation of α-glucosidase inhibitory activity and UHPLC-ESI-QTOF-MS based metabolic profiling of endophytic fungi Alternaria alternata BRN05 isolated from seeds of Swietenia mac... by Piyush Kumar, Sai Anand Kannakazhi Kantari, Ranendra Pratap Biswal, Prasanth Ghanta, Malleswara Dharanikota

“…This study aims to explore and identify novel bioactive metabolites with anti-diabetes potential from Alternaria alternata BRN05, an endophytic fungus isolated from a well-known medicinal plant Swietenia macrophylla King. …”
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Random antimicrobial peptide mixtures as non-antibiotic antimicrobial agents for cultured meat industry by Idan Yakir, Einav Cohen, Sharon Schlesinger, Zvi Hayouka

“…Hence, there is an urgent need to develop novel and safe non-antibiotic antimicrobial agents. …”
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UNet-Att: a self-supervised denoising and recovery model for two-photon microscopic image by Yuer Lu, Yongfa Ying, Chen Lin, Yan Wang, Jun Jin, Xiaoming Jiang, Jianwei Shuai, Xiang Li, Jinjin Zhong

“…To improve two-photon microscopy image denoising effectiveness, by experimenting on real two-photon microscopy images, we propose a novel deep learning framework, the UNet-Att model, which integrates a specifically tailored UNet++ architecture with attention mechanisms. …”
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Assessing static balance control improvement following cataract surgery using a smartphone by Lorrana de Souza Azevedo, Newton Quintino Feitosa, Enzo Gabriel Rocha Santos, Márcio Augusto Moraes Alvarez, Lucciano Augusto Ximenes Norat, Gabriel Izan Santos Botelho, Anderson Belgamo, Gustavo Henrique Lima Pinto, Ketlin Jaqueline Santana Castro, Bianca Callegari, Anselmo de Athayde Costa e Silva, Raílson Cruz Salomão, André dos Santos Cabral, Alexandre Antônio Marques Rosa, Givago Silva Souza

“…Cataract removal surgery has been established as a means to enhance visual acuity and balance control. The advent of novel technologies, such as accelerometers integrated into smartphones, provides an opportunity to assess static balance control. …”
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Bibliometric insights into astrocytic roles in depression and treatment by Linsun Lin, Linsun Lin, Ziyi Guo, Zhuoyu Ren, Yanchen Feng, Peigang Fang, Tao Wang, Min Chen, Min Chen

“…We hope that this study will facilitate a broader integration of basic and clinical research, offering novel approaches for the treatment of depression.…”
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High-Resolution Geochemical Data Mapping With Swin Transformer-Convolution-Based Multisource Geoscience Data Fusion by Ye Yuan, Shuguang Zhou, Jianhua Bian, Jinlin Wang, Wei Han, Jining Yan

“…This article proposes a novel multimodal spatial–spectral fusion model with swin transformer and convolutional networks for regression (MSSF-SCR). …”
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A Hybrid Fuzzy Wavelet Neural Network Model with Self-Adapted Fuzzy c-Means Clustering and Genetic Algorithm for Water Quality Prediction in Rivers by Mingzhi Huang, Di Tian, Hongbin Liu, Chao Zhang, Xiaohui Yi, Jiannan Cai, Jujun Ruan, Tao Zhang, Shaofei Kong, Guangguo Ying

“…Water quality prediction is the basis of water environmental planning, evaluation, and management. In this work, a novel intelligent prediction model based on the fuzzy wavelet neural network (FWNN) including the neural network (NN), the fuzzy logic (FL), the wavelet transform (WT), and the genetic algorithm (GA) was proposed to simulate the nonlinearity of water quality parameters and water quality predictions. …”
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Redox-dependent purine degradation triggers postnatal loss of cardiac regeneration potential by Yuichi Saito, Yuki Sugiura, Akane Sakaguchi, Tai Sada, Chihiro Nishiyama, Rae Maeda, Mari Kaneko, Hiroshi Kiyonari, Wataru Kimura

“…These findings highlight a novel role of xanthine metabolism as a redox-dependent metabolic regulator of cardiac regeneration potential.…”
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Autogenous Electron Acceleration by Ion Flow Vortex in Space Plasmas by C. M. Liu, J. B. Cao, Y. Y. Liu, E. A. Kronberg, X. N. Xing, B. N. Zhao, P. W. Daly

“…Our observations, suggesting that the ion flow vortex can serve as novel electron accelerators, can be fundamentally important for understanding energetic phenomena in the cosmos, such as nonthermal emissions near astrophysical jets and killer electrons in geospace.…”
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Improving diagnostic precision in thyroid nodule segmentation from ultrasound images with a self-attention mechanism-based Swin U-Net model by Changan Yang, Muhammad Awais Ashraf, Mudassar Riaz, Pascal Umwanzavugaye, Kavimbi Chipusu, Kavimbi Chipusu, Hongyuan Huang, Yueqin Xu

“…These challenges directly affect the precision of thyroid disorder diagnoses, which are crucial for metabolic and hormonal regulation.MethodsThis study proposes a novel segmentation approach utilizing a Swin U-Net architecture enhanced with a self-attention mechanism. …”
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Sequential transcriptome profiling: comparative analysis of normal and canine lymphoma preceding detailed T-cell and B-cell subtype comparison by Yeji Kim, Yeji Kim, Jihyun Kim, Jihyun Kim, Yunji Song, Yunji Song, Keunhwan Jang, Se Eun Kim, Se Eun Kim, Se Eun Kim, Ha-Jung Kim, Ha-Jung Kim

“…Ongoing research spans multiple domains, aiming to uncover novel therapeutic targets, including small molecular weight inhibitors, antibody treatments, and subtype-specific selective agents.MethodsTranscriptional profiling was performed on canine lymphoma samples to identify genes and functional pathways associated with pathogenesis, treatment response, and prognosis. …”
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Tear Film Proteome of Healthy Domestic Cats by Jéssica Fontes Veloso, Paula Elisa Brandão Guedes, Luciana Carvalho Lacerda, Juliano Oliveira Santana, Irma Yuliana Mora-Ocampo, Carlos Priminho Pirovani, Arianne Pontes Oriá, Alexandre Dias Munhoz, Renata Santiago Alberto Carlos

“…Others were considered novel in tear film samples of all species: cyclin-dependent protein kinase, serine/arginine repetitive matrix protein, apelin receptor, secretory protein related to C1q/TNF, Wee1, α-1,4 glucan phosphorylase, and WD repeat domain 1. …”
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Designing multi-function rapid right angle set slurry compositions for a high pressure-high temperature well by Pooria Kianoush, Mostafa Gomar, Nasser Keshavarz Faraj Khah, Seyednooroldin Hosseini, Ali Kadkhodaie, Shahaab Varkouhi

“…This study aimed to design a novel multi-target cement formula to deter gas penetration and prevent complications such as formation creep and cement deterioration. …”
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