Susceptibility map-weighted MRI can distinguish tremor-dominant Parkinson’s disease from essential tremor by Sungyang Jo, Chong Hyun Suh, Sangjin Lee, Jihyun Lee, MyungKi Yoon, Hwon Heo, Woo Hyun Shim, Sang Joon Kim, Eung Yeop Kim, Sun Ju Chung

“…Patients with PD exhibit loss of the dorsal nigral hyperintensity on brain magnetic resonance imaging (MRI). Novel MRI-based approaches, including susceptibility map-weighted imaging (SMwI), allow visualization of the dorsal nigral hyperintensity at an increased resolution. …”
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CASP5 associated with PANoptosis promotes tumorigenesis and progression of clear cell renal cell carcinoma by Kangkang Yang, Yushuang Wang, Yuli Jian, Bo Wang, Hao Du, Yuqing Xia, Jianlei Bi, Meihua Guo, Zhi Li, Ning Wang

“…Together, the innovative risk model using PANoptosis-associated genes effectively forecasts the tumor microenvironment and survival rates for ccRCC, offering a novel approach to the early, precise diagnosis of ccRCC and the advancement of personalized treatment strategies.…”
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Evaluation of allergenic protein profiles in three Chinese high-oleic acid peanut cultivars using NanoLC-Orbitrap mass spectrometry by Xinke Yang, Haochen Bai, Lijun Yin, Jin Wang, Wentong Xue, Xin Jia

“…Through the peptide-filtering pipeline, three novel peptide markers, IVQIEAKPNTLVLPK, SSNPDIYNPQAGSLR and AQSENYEYLAFK surrogate to Ara h 1, Ara h 3 with high abundance, good MS response and highly reliability were identified, which can be used as candidate peptide markers for the detection of peanut allergens in different food matrices.…”
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Synergistic effects of PS-NPs and Cd on ovarian toxicity in adolescent rats: Ferroptosis by induction of mitochondrial redox imbalance via the SIRT3-SOD2/Gpx4 pathway by Hua Wu, Lihua Feng, Huang Wu, Lihong Wang, Hengyi Xu, Fen Fu

“…Our results suggested that co-exposure to PS-NPs and Cd may trigger ferroptosis by inhibiting the SIRT3-SOD2/Gpx4 pathway, leading to mitochondrial redox imbalance, which provided novel insights into reproductive toxicity due to the interaction of PS-NPs and Cd during adolescence.…”
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Tailored biomimetic nanoreactor improves glioma chemodynamic treatment via triple glutathione depletion and prompt acidity elevation by Ya Wen, Qiansai Qiu, Feng Feng, Yujuan Zhu, Jianquan Zhang, Zesheng Sun, Tuodi Zhang, Wei Shi, Jinlong Shi

“…Through in vitro and in vivo experiments, we demonstrate the exhaustive and synchronous regulation of Fenton chemistry could potentially serve as a novel CDT strategy for glioma.…”
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A Large Ship Detection Method Based on Component Model in SAR Images by Tiancheng Dong, Taoyang Wang, Xuefei Li, Jianzhi Hong, Maoqiang Jing, Tong Wei

“…This article decomposes the large ship detection problem into the detection of individual ship components (including tail, hull, and head), proposing a novel component-based detection method for large ship targets in SAR images. …”
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Triplet Electron Exchange in Carbon Nanodots‐assisted Long‐persistent near‐infrared Chemiluminescence for Oncology Synergistic Imaging and Therapy by Run‐Wei Song, Tian‐Ci Jiang, Xue‐Yang Zhang, Cheng‐Long Shen, Qing Lou, Chong‐Xin Shan

“…As a proof‐of‐concept, the photosensitizers of carbon nanodots (CDs)‐loaded chlorin e6 (CDs‐Ce6) are designed and integrated with the peroxalate molecules, and the as‐prepare polymer carbon nanodots (p‐CDs) exhibit novel tumor microenvironment (TME)‐responsive long‐persistent near‐infrared CL and photochemical reactions, evoking the in vivo imaging and synergistic dynamic therapy in tumor tissue. …”
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Dual-Polarized Wideband Filtering Antenna Array Based on Stacked-PCB Structure by Matti Kuosmanen, Sten E. Gunnarsson, Johan Malmstrom, Juha Ala-Laurinaho, Jari Holopainen, Ville Viikari

“…The low-pass filtering in the antenna elements reduces the requirement for the front-end filtering between the antenna and the microwave electronics, resulting in improved overall out-of-band suppression, size reduction, and lower cost. The array employs a novel stacked-PCB structure, where simple two-sided PCBs are stacked on top of each other. …”
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Offsite modular construction adoption in developing countries: Partial least square approach for sustainable future by Syed Saad, Kumeel Rasheed, Syed Ammad, Muhammad Hasnain, Habib Ullah, Abdul Hannan Qureshi, Aawag Mohsen Alawag, Muhammad Altaf, Touseef Sadiq

“…This study fills a critical gap by developing a novel framework that integrates the analysis of Offsite Modular Adoption Barriers (OMABs), i.e. resource availability, process management, and issues/perceptions, with the pursuit of overall sustainable future needs (OSFN) in residential projects. …”
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Influence of single-pass caliber rolling on the microstructural evolution and mechanical properties of Mg10Gd binary alloy by H. Yu, Z.K. Liu, Y. Liu, W. Yu, Y.L. Xu, C. Liu, B.A. Jiang, S.H. Park, K.S. Shin

“…In addition, caliber rolling also provides a novel approach for the design of Mg alloys with uniform bimodal structures that exhibit both high strength and ductility.…”
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New Lightning‐Derived Vertical Total Electron Content Data Provide Unique Global Ionospheric Measurements by Erin H. Lay, Jeffery D. Tippmann, Kyle C. Wiens, Sarah E. McDonald, Anthony J. Mannucci, Xiaoqing Pi, Anthea Coster, R. Marc Kippen, Michael J. Peterson, Rob Redmon

“…Abstract A newly released, novel ionospheric data set of global gridded vertical total electron content (VTEC) is introduced in this paper. …”
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Study of dynamic brain function in irritable bowel syndrome via Hidden Markov Modeling by Chuan Jing, Tianci Liu, Qingzhou Li, Chuan Zhang, Baijintao Sun, Xuezhao Yang, Yutao You, Jixin Liu, Hanfeng Yang

“…The reconfiguration of HMM states over time scales in IBS patients was associated with abnormal activity in the default mode network (DMN), sensorimotor network (SMN), and cingulo-opercular network (CON).ConclusionThis study offers novel insights into the dynamic reorganization of brain activity patterns in IBS and elucidates potential links between these patterns and IBS-related emotional regulation and symptom experience, thereby contributing to a deeper understanding of the neural mechanisms underlying IBS.…”
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HPV E6/E7, hTERT, and Ki67 mRNA RT-qPCR Assay for Detecting High-Grade Cervical Lesion with Microscope Slides by Geehyuk Kim, Jemberu Taye, Kwangmin Yu, Sunyoung Park, Jungho Kim, Sunghyun Kim, Dongsup Lee, Hye-young Wang, Kwang Hwa Park, Hyeyoung Lee

“…And the study suggests clinical slide cell samples could be effectively used in the context of retrospective studies to identify novel biomarkers.…”
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Physically Meaningful Surrogate Data for COPD by Harry J. Davies, Ghena Hammour, Hongjian Xiao, Patrik Bachtiger, Alexander Larionov, Philip L. Molyneaux, Nicholas S. Peters, Danilo P. Mandic

“…To this end, we introduce a novel COPD-simulator, a physical apparatus with an easy to replicate design which enables rapid and effective generation of a wide range of COPD-like data from healthy subjects, for enhanced training of deep learning frameworks. …”
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Infusion of Autologous Retrodifferentiated Stem Cells into Patients with Beta-Thalassemia by Ilham Saleh Abuljadayel, Tasnim Ahsan, Huma Quereshi, Shakil Rizvi, Tamseela Ahmed, Sabiha Mirza Khan, Jawaid Akhtar, Ghazi Dhoot

“…No adverse side effects in response to the infusion of autologous RSC were noted.This novel clinical procedure may profoundly modify the devastating course of many genetic disorders in an autologous setting, thus paving the way to harnessing pluripotency from differentiated cells to regenerate transiently an otherwise genetically degenerate tissue such as thalassemic blood.…”
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Encapsulation of Hydrogen Peroxide in PVA/PVP Hydrogels for Medical Applications by Natalie Mounayer, Sivan Shoshani, Elena Afrimzon, Taly Iline-Vul, Moris Topaz, Ehud Banin, Shlomo Margel

“…The present study introduces a novel, straightforward method for preparing biodegradable hydrogels based on polyvinyl alcohol (PVA) and polyvinyl pyrrolidone (PVP) for medical applications. …”
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How to convert a 3D printer to a personal automated liquid handler for life science workflows by Dulguunnaran Naranbat, Benjamin Phelps, John Murphy, Anubhav Tripathi

“…The PALH system was evaluated through common life science assays, including preparing real-time PCR samples, end-point PCR with novel pipet-based downstream purification, and genomic DNA extraction from peripheral whole blood. …”
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Lymph Node Adiposity and Metabolic Dysfunction-Associated Steatotic Liver Disease by Jessica M. Rubino, Natalie Yanzi Ring, Krishna Patel, Xiaoqing Xia, Todd A. MacKenzie, Roberta M. diFlorio-Alexander

“…Lymph node adiposity (LNA) is a novel marker of adiposity identified within axillary lymph nodes on screening mammography. …”
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Human Action Recognition Using Difference of Gaussian and Difference of Wavelet by Gopampallikar Vinoda Reddy, Kongara Deepika, Lakshmanan Malliga, Duraivelu Hemanand, Chinnadurai Senthilkumar, Subburayalu Gopalakrishnan, Yousef Farhaoui

“…The major challenge in HAR is the design of an action descriptor that makes the HAR system robust for different environments. A novel action descriptor is proposed in this study, based on two independent spatial and spectral filters. …”
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Evaluation of the Antioxidant and Cytotoxic Activities on Cancer Cell Line of Extracts of Parasitic Plants Harvested in Tunisia by Imen Ben Attia, Paolo Zucca, Flaminia Cesare Marincola, Mariella Nieddu, Alessandra Piras, Antonella Rosa, Antonio Rescigno, Mohamed Chaieb

“…These data suggest that, despite the extreme climate conditions and the damage that can result, the studied desert parasitic plants can represent a novel and precious source of metabolites, with promising biological activities.…”
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